Keywords: منطقه تعریف مکمل; ADA; anti-drug antibody; ACP; assay cutpoint; CDM; compact disc microstructures; CDR; complementary determining region; Fc; Fragment crystallizable; F/T; ratio of free to total drug concentrations; iNAb; indirect NAb assessment; LLRD; lower limit of relia
مقالات ISI منطقه تعریف مکمل (ترجمه نشده)
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Keywords: منطقه تعریف مکمل; Polysialic acid; Tegaserod; Mimetic; Peripheral nerve; Regeneration; Glycan; Drug repurposing; CDR; complementary determining region; cGN; cerebellar granule neuron; DRG; dorsal root ganglion; ELISA; enzyme-linked immunosorbent assay; FBA; foot base angle
Keywords: منطقه تعریف مکمل; scFv; single-chain fragment variable; Fab; fragment antigen binding; PBMC; peripheral blood mononuclear cell; V; variable; VH; variable heavy chain; VL; variable light chain; Vκ; variable kappa light chain; Vλ; variable lambda light chain; PPE; periplas
Elimination of eosinophils using anti-IL-5 receptor alpha antibodies effectively suppresses IL-33-mediated pulmonary arterial hypertrophy
Keywords: منطقه تعریف مکمل; ADCC; antibody dependent cell-mediated cytotoxicity; IL; IL-5; IL-5Rα; IL-5 receptor α chain; ILC2; group 2 innate lymphoid cell; Th2; T helper type 2; PAH; pulmonary arterial hypertension; CDR; complementary determining region; SMA; smooth muscle actin
Developmental expression of B cell molecules in equine lymphoid tissues
Keywords: منطقه تعریف مکمل; CDR; complementary determining region; DG; days of gestation; DGKA; diacylglycerol kinase alpha; FCS; fetal calf serum; FGL2; fibrinogen-like protein 2; Ig; immunoglobulin; IGK; Ig kappa light chain; IGL; Ig lambda light chain; IGLJ; Ig lambda joining gen
Development and characterization of an αvβ6-specific diabody and a disulfide-stabilized αvβ6-specific cys-diabody
Keywords: منطقه تعریف مکمل; NOTA-maleimide; 1,4,7-triazacyclononane-1,4,7-triacetic acid maleimide; Ni-NTA; nickel nitrilotriacetic acid; RCY; radiochemical yield; RCP; radiochemical purity; mAbs; monoclonal antibodies; immuno-PET; immuno-positron emission tomography; kDa; kilodalto
Next-generation optimized biotherapeutics - A review and preclinical study
Keywords: منطقه تعریف مکمل; ADAs; anti-drug antibodies; ADC; antibody drug conjugate; ADCC; antibody-dependent cell-mediated cytotoxicity; ATL; adult T-cell leukemia-lymphoma; CCR4; CC chemokine receptor 4; CDC; complement-dependent cytotoxicity; CDR; complementary determining regio
Arrayed antibody library technology for therapeutic biologic discovery
Keywords: منطقه تعریف مکمل; CDR; complementary determining region; mAb; monoclonal antibody; V; variable; D; diversity; J; joining; GPCR; G-protein coupled receptor; CVB; culture vessel block; LIMS; laboratory information management system; Fab; fragment antigen-binding; SAR; struct
Innate autoreactive B cells as antigen-presenting cells in the induction of tolerance to conserved keratin polypeptide
Keywords: منطقه تعریف مکمل; BCRs; B cell receptors; APC; antigen presenting cells; AK auto-Ab; anti-keratin autoantibody; LN; lymph nodes; TCR; T-cell antigen receptor; Ig; immunoglobulin; CDR; complementary determining region; FR; framework region; NHSB; N-hydroxysuccinimido-biotin
Evaluation of three different formats of a neutralizing single chain human antibody against toxin Cn2: Neutralization capacity versus thermodynamic stability
Keywords: منطقه تعریف مکمل; CDR; complementary determining region; CH; constant domain heavy chain; CL; constant domain light chain; ELISA; enzyme-linked immunosorbent assay; FR; framework region; KD; dissociation constant; RMSD; root mean square deviation; SCM; spectra center of ma
Anticorps monoclonaux à usage thérapeutique : spécificités du développement clinique, évaluation par les agences, suivi de la tolérance à long terme
Keywords: منطقه تعریف مکمل; anticorps monoclonaux; essais cliniques, phase I; essais cliniques, phase II; essais cliniques, phase IV; AcMo; anticorps monoclonaux; ADCC; antibody dependent cellular cytotoxicity; Afssaps; Agence française de sécurité sanitaire des produits de santÃ
Light chain somatic mutations change thermodynamics of binding and water coordination in the HyHEL-10 family of antibodies
Keywords: منطقه تعریف مکمل; CDR; complementary determining region; HEL; hen egg white lysozyme; SPR; surface plasmon resonance; ITC; isothermal titration calorimetry; FR; framework residues; RU; response unit; IgG; immunoglobin G; SASA; solvent accessible surface area; Enthalpy; Van
Mutational and inhibitory analysis of a catalytic antibody. Implication for drug discovery
Keywords: منطقه تعریف مکمل; IgG; immunoglobulin G; LB; Luria-Bertani; SPR; surface plasmon resonance; CDR; complementary determining region; Catalytic antibody; scFv; β-Lactamase; Anti-idiotype; Idiotypic network; Cyclic peptide;
Recombinant polymeric IgG anti-Rh: a novel strategy for development of direct agglutinating reagents
Keywords: منطقه تعریف مکمل; Rh; Rhesus; RBC; red blood cell; Ig; immunoglobulin; mAbs; monoclonal antibodies; Ab; antibody; AHG; anti-human globulin; CHO; Chinese hamster ovary; IAT; indirect anti-globulin test; PBS; phosphate buffered saline solution; BSA; bovine serum albumin; EDT
Phage-display derived single-chain fragment variable (scFv) antibodies recognizing conformational epitopes of Escherichia coli heat-labile enterotoxin B-subunit
Keywords: منطقه تعریف مکمل; E. coli; Escherichia coli; scFv; single-chain Fv antibody fragment; ELISA; enzyme-linked immunosorbent assay; GM1; monoganglioside-GM1 (Galβ-3GalNacβ1-(neu5Acα2-3)-4Galβ1-4Glcβ1-cer); Etx; heat-labile enterotoxin; EtxB5; heat-labile enterotoxin B pen
Antibodies to the superantigenic site of HIV-1 gp120: Hydrolytic and binding activities of the light chain subunit
Keywords: منطقه تعریف مکمل; Ab; antibody; AMC; 7-amino-4-methylcoumarin; BCR; B cell receptor; BSA; bovine serum albumin; CDR; complementary determining region; CHAPS; 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonic acid; EP; electrophile; FR; framework region; gp120SAg; su
Display and selection of chicken IgA Fab fragments
Keywords: منطقه تعریف مکمل; Calpha1; first domain of the chicken alpha heavy chain; CDR; complementary determining region; PIII; geneIII capsid protein of M13 phage; RBS; ribosomal binding site; Phage display; IgA Fab; Chicken; Eimeria acervulina;
CDR3 sequence preference of TCRBV8S2+ T cells within the CNS does not reflect single amino acid dependent avidity expansion
Keywords: منطقه تعریف مکمل; CDR; complementary determining region; CNS; central nervous system; EAE; experimental autoimmune encephalomyelitis; FACS; fluorescence activated cell sorter; GP; guinea pig; MBP; myelin basic protein; RT1; MHC of rat; TCR; T cell receptor; TCRBV; T cell r
Detection of one VH antibody sequence in both healthy donors and urticaria patients
Keywords: منطقه تعریف مکمل; VH; variable heavy chain; VL; variable light chain; CDR; complementary determining region; CIU; chronic idiopathic urticaria; FcεRIα; α-chain of the high-affinity IgE receptor; CT; threshold cycle number; MGB; Minor groove binder; PBGD; porphobilinogen