
Vitamin E metabolite 13â²-carboxychromanols inhibit pro-inflammatory enzymes, induce apoptosis and autophagy in human cancer cells by modulating sphingolipids and suppress colon tumor development in mice
Keywords: 13â²-COOH; 13â²-carboxychromanol; αT, γT, or δT; α, γ, or δ-tocopherol; γTE or δTE; γ, δ-tocotrienol; δT-13'-COOH or δT-13â²; 13â²-COOH derived from δT; δTE-13â²-COOH or δTE-13â²; 13â²-COOH derived from δTE; COX; cyclooxygenase; 5