کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5589853 | 1404665 | 2016 | 36 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Mitochondrial genome of Cricetulus migratorius (Rodentia: Cricetidae): Insights into the characteristics of the mitochondrial genome and the phylogenetic relationships of Cricetulus species
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کلمات کلیدی
dNTPL-strandH-strandMCMCNADH dehydrogenaseETASdeoxy-ribonucleoside triphosphateddH2OMitogenomeCSBcytBGTRPcGCOXAICATP synthase - ATP سنتازMitochondrial DNA - DNA میتوکندریاdouble distilled water - آب دوتاییagarose gel electrophoresis - الکتروفورز ژل آگارزATPase - ایتیپیایزها conserved sequence blocks - بلوک توالی محافظت شدهBootstrap - بوت استرپBayesian inference - تخمین بیزین یا استنباط بیزیMaximum likelihood - حداکثر احتمالMaximum parsimony - حداکثر پارسیمونیD-loop - حلقه DmtDNA - دیانای میتوکندریاییheavy strand - رشته سنگینlight strand - رشته نورPhylogenetic relationships - روابط فیلوژنتیکgeneral time reversible - زمان عمومی برگشت پذیرMarkov chain Monte Carlo - زنجیره مارکف مونت کارلوAge - سنCytochrome b - سیتوکروم بcytochrome c oxidase - سیتوکروم سی اکسیدازAkaike information criterion - معیار اطلاعاتی آکائیکMyr - میرmillion years - میلیون سالpolymerase chain reaction - واکنش زنجیره ای پلیمرازPCR - واکنش زنجیرهٔ پلیمرازMitochondrial genome - ژنوم میتوکندریابی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
ژنتیک
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Cricetulus migratorius is widely distributed in the northwestern arid regions of China. Here, the complete mitochondrial genome (mitogenome) of C. migratorius is reported, to our knowledge, for the first time. It was found to be 16,246Â bp in length, including 13 protein-coding genes (PCGs), 2 rRNA genes, 22 tRNA genes, and one control region, and showed characteristics typical of the vertebrate mitogenome. Comparative analyses of mitogenomes of Cricetulus species showed that hamster mitogenomes had the same arrangement and organizational structure. The base composition was AT-rich for all Cricetulus species. We elaborated the PCG sequence and found that the main differences in the start and stop codons were in the ND3 gene; the most frequently used codons were AUU (Ile) and CUA (Leu), and the AT-content at the 3rd position was lower than that at 1st and 2nd positions in all Cricetulus species. The second tRNAser had lost the dihydrouridine stem-loop structure, which is found in all Cricetulus species. We also elucidated the structure of the control region (the extended termination associated sequences, the central conserved sequences, and the conserved sequence blocks), and the putative origin of replication for the light strand in all Cricetulus species. Based on mitogenome data with four reconstructed methods, phylogenetic trees showed high resolution in the divergent clades within Cricetulus. The results indicated that Cricetulus kamensis is at basal position, and has the earliest split among all Cricetulus species. Cricetulus griseus and Cricetulus longicaudatus clustered in a subclade, and were separate from C. kamensis. As previous studies have shown, Tscherskia triton is part of Cricetulus with high support value. It is noteworthy that C. migratorius is a young species, and has a close relationship with Allocricetulus eversmanni within Cricetulus, which is closer to the subgenus Allocricetulus.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Gene - Volume 595, Issue 1, 20 December 2016, Pages 121-129
Journal: Gene - Volume 595, Issue 1, 20 December 2016, Pages 121-129
نویسندگان
Li Ding, Wenjia Li, Jicheng Liao,