Keywords: T2DM; type 2 diabetes mellitus; CM; conditioned medium; ATM; adipose tissue macrophage; TNFα; tumor necrosis factor alpha; LPS; lipopolysaccharide; IFNγ; interferon gamma; iNOS; inducible nitric oxide synthase; COX-2; cyclooxygenase-2; MCP-1; monocyte c
مقالات ISI (ترجمه نشده)
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Keywords: ACPA; anticitrullinated protein antibody; CCP; cyclic citrullinated peptide; CTD; connective tissue disease; CXCL; CXC chemokine ligand; Dlco; diffusing capacity of lung for carbon monoxide; DMARD; disease-modifying antirheumatic drug; HRCT; high resoluti
Keywords: APC; antigen presenting cell; cCHP; cationic type of cholesteryl group-bearing pullulan; CCL; CC chemokine ligand; CCR; CC chemokine receptor; CMIS; common mucosal immune system; CT; cholera toxin; CTB; cholera enterotoxin B subunit; CXCL; CXC chemokine l
Keywords: Decorin; Lumican; Fibromodulin; Toll-like receptor; Matrix metalloproteinases; 5/6-Nx; 5/6-nephrectomized Sprague-Dawley rats; ADAMTS; a disintegrin and metalloproteinase with thrombospondin motifs; ALK; activin like kinase; ATS; hymocyte serum; BGN (Bgn)
Keywords: APC(s); antigen presentation cell(s); ARG1; arginase-1; Breg(s); regulatory B (cells); CAF(s); cancer-associated fibroblast(s); CD; cluster of differentiation protein; CD40L; cluster of differentiation protein 40 ligand; C/EBP; CAAT/enhancer binding prote
Keywords: Carotenes; Xanthophylls; NF-κB; Nrf2; Transcription factors; Chronic diseases; AMD; age-related macular degeneration; ARE; antioxidant response element; BCDO2; β-carotene dioxygenase 2; BCO1; β-carotene 15,15â²-oxygenase 1; CAT; catalase; CCL2; chemok
Keywords: A20; tumor necrosis factor, alpha-induced protein 3; ALT; alanine aminotransferase; AST; aspartate aminotransferase; Atf3; activating transcription factor 3; Cxcl; chemokine (C-X-C motif) ligand; Gapdh; glyceraldehydes-3-phosphate dehydrogenase; Glut2; gl
Keywords: CXCL; chemokines with an amino acid between the two N-terminal cysteine residues; CCL; chemokines with an amino acid neighbouring the two N-terminal cysteine residues; CT; threshold cycle; GAD; glutamic acid decarboxylase; HSP60; heat-shock protein 60; IF
A natural “GA” insertion mutation in the sequence encoding the 3â²UTR of CXCL12/SDF-1α: Identification, characterization, and functional impact on mRNA splicing
Keywords: aa; amino acid(s); AREs; AU-rich elements; ARMS; amplification refractory mutation system; bp; base pair(s); cDNA; DNA complementary to RNA; cpm; counts per minute; CXCL; C-X-C motif chemokine ligand; CXCR; C-X-C chemokine receptor; d; deoxyribo; DMSO; di
Transcriptome analysis of bovine lymphocytes stimulated by Atractylodis macrocephalae Koidz. polysaccharides in vitro
Keywords: RAMPtp; total polysaccharides from Atractylodis macrocephalae Koidz.; SMLN; supramammary lymph node; IFN; interferon; IFIT; interferon-induced protein; ISG; interferon-stimulated gene; OAS; 2â²-5â²-oligoadenylate synthetase; RSAD; radical S-adenosyl met
Sulfatase 1 mediates the attenuation of Ang II-induced hypertensive effects by CCL5 in vascular smooth muscle cells from spontaneously hypertensive rats
Keywords: Sulfatases; CCL5; Ang II type 2 receptor; Hypertension; CCL; CC-chemokine ligand; CXCL; CXC-chemokine ligand; Sulf1; sulfatase 1; Sulf2; sulfatase 2; VSMC; vascular smooth muscle cell; SHR; spontaneously hypertensive rat; Ang II; angiotensin II; AT1 R; An
Acute extracellular matrix, inflammatory and MAPK response to lengthening contractions in elderly human skeletal muscle
Keywords: LC; lengthening contractions; ECM; extracellular matrix; TGF-β; transforming growth factor-beta; TGF-βRII; transforming growth factor-beta receptor II; SMAD; Mothers against decapentaplegic homolog; MAPK; mitogen activated protein kinase; JNK; c-Jun N-t
Necroptosis in 3-chloro-1, 2-propanediol (3-MCPD)-dipalmitate-induced acute kidney injury in vivo and its repression by miR-223-3p
Keywords: 3-MCPD; 3-chloro-1,2-propanediol; 3â²UTR; 3â² un-translated region; AKI; acute kidney injury; BMD10; Benchmark doses; BMDL10; BMD Lower Confidence Limit; BW; body weight; CXCl; chemokine (C-X-C motif) ligand; DE; differentially expressed; DR6; death rec
Topically applied azaphenothiazines inhibit experimental psoriasis in mice
Keywords: TNF α; tumor necrosis factor α; IL; interleukin; LPS; lipopolysaccharide; IMQ; imiquimod; KERTr; human skin keratinocyte cell line; CXCL; C-X-C motif ligand; poly(I:C); polyinosinic:polycytidylic acid; LF; lipofectamine; Psoriasis; Mice; Azaphenothiazin
Effects of the stimuli-dependent enrichment of 8-oxoguanine DNA glycosylase1 on chromatinized DNA
Keywords: 8-oxoG; 8-oxo-7, 8-dihydroguanine; AP; apurinic/apyrimidinic site in DNA; APE1; apurinic/apyrimidinic endonuclease 1; BER; base excision repair; ChIP; chromatin immunoprecipitation assays; ChIP-seq; chromatin immunoprecipitation assays followed by DNA seq
HDAC2 Suppresses IL17A-Mediated Airway Remodeling in Human and Experimental Modeling of COPD
Keywords: airway inflammation; airway remodeling; COPD; HDAC2; IL-17A; CS; cigarette smoke; CSE; cigarette smoke extract; CXCL; chemokine (C-X-C motif) ligand; ECM; extracellular matrix; HBE; human bronchial epithelial; HDAC; histone deacetylase; HRCT; high-resolut
Galangin's potential as a functional food ingredient
Keywords: Galangin; Propolis; Alpinia officinarum; Functional food ingredient; Polypharmacology; Flavonoid; AChE; acetylcholinesterase; AD; Alzheimer's disease; ADME; Administration, Distribution, Metabolism and Excretion; AHR; airway hyperresponsive; AhR; aryl h
Human Fetal-Derived Enterospheres Provide Insights on Intestinal Development and a Novel Model to Study Necrotizing Enterocolitis (NEC)
Keywords: Necrotizing Enterocolitis; Fetal Organoids; Enteroids; AD; adult duodenal; AEnS; adult-derived enterospheres; CLDN; claudin; ÎÎCT; relative threshold cycle; CXCL; chemokine (C-X-C motif) ligand; DMEM; Dulbecco's modified Eagle medium; EGF; epidermal gro
MicroRNAs 15A and 16-1 Activate Signaling Pathways That Mediate Chemotaxis of Immune Regulatory B cells to Colorectal Tumors
Keywords: Immune Regulation; Tumor Immunosuppression; microRNA15A/16-1; Colon Cancer Model; AD; azoxymethane with dextran sodium sulfate; CAC; colitis-associated colorectal cancer; CRC; colorectal cancer; CXCL; chemokine (C-X-C motif) ligand; DSS; dextran sodium
Role of miRNAs in cell signaling of cancer associated fibroblasts
Keywords: ATG; autophagy related; CAF; cancer associated fibroblasts; CCL; C-C motif chemokine ligand; CDK2; cyclin-dependentkinase 2; CXCL; chemokine(C-X-C motif) ligand; DRAM; damage-regulated autophagy modulator; ECM; extracellular matrix; EMT; epithelialto mese
Toll-Like Receptor-Mediated Upregulation of CXCL16 in Psoriasis Orchestrates Neutrophil Activation
Keywords: CXCL; CXC chemokine ligand; CXCR; CXC chemokine receptor; DC; dendritic cell; LPS; lipopolysaccharide; NA; nucleic acid; PBMC; peripheral blood mononuclear cell; poly(IC); polyinosinic-polycytidylic acid; slan; 6-sulfo LacNAc; TNF-α; tumor necrosis fact
Optineurin Insufficiency Disbalances Proinflammatory and Anti-inflammatory Factors by Reducing Microglial IFN-β Responses
Keywords: ALS; amyotrophic lateral sclerosis; BMDM; bone marrow-derived macrophages; C9orf72; chromosome 9 open-reading frame 72; CNS; central nervous system; CXCL; CXC chemokine ligand; DAMPs; damage-associated molecular patterns; DMEM; Dulbecco's Modified Eagle
Peroxisome proliferator activated receptor gamma (PPAR-γ) ligand pioglitazone regulated gene networks in term human primary trophoblast cells
Keywords: BNF; beta-naphthoflavone; CCL; C-C motif chemokine ligand; CT; cytotrophoblast; CXCL; C-C-X-C motif chemokine ligand; CYP; cytochrome P450 enzyme superfamily; ELOVL4; fatty acid elongase 4; EVCT; extravillous cytotrophoblast; GEO; Gene Expression Omnibus;
Optimizing conventional DMARD therapy for Sjögren's syndrome
Keywords: 6-MP; 6-mercaptopurine; 6-T-GTP; 6-thioguanine triphosphate; ABT; abatacept; Ach; acetylcholine; ALAT; alanine amino transferase; AZA; azathioprine; BAFF; B cell activating factor; Bcl-6; B cell lymphoma 6; bDMARDs; biological disease modifying antirheuma
Therapeutic implication of vascular endothelial growth factor receptor-1 (VEGFR-1) targeting in cancer cells and tumor microenvironment by competitive and non-competitive inhibitors
Keywords: ADCC; antibody dependent cell-mediated cytotoxic activity; ALL; acute lymphoid leukemia; AML; acute myeloid leukemia; CXCL; C-X-C motif chemokine ligand; ECM; extra-cellular matrix; EGFR; epidermal growth factor receptor; ERK; extracellular signal-regulat
TRAF3IP2 mediates TWEAK/TWEAKR-induced pro-fibrotic responses in cultured cardiac fibroblasts and the heart
Keywords: Fn14; CIKS; Act1; adverse cardiac remodeling; migration; Act1; NF-kappa B Activator 1; ANP; atrial natriuretic peptide; AP-1; activator protein-1; CCL; C-C Motif Chemokine Ligand; CD; Cluster of Differentiation; CF; cardiac fibroblasts; CIKS; Connection t
Nanomedicines for the treatment of hematological malignancies
Keywords: BMSC; Bone marrow stromal cell; BM; bone marrow; VCAM1; Vascular cell adhesion molecule 1; VLA-4; Very late antigen-4; HM; hematological malignancy; CLL; Chronic lymphocytic leukemia; ICAM1; Intercellular adhesion molecule 1; VEGF; Vascular endothelial gr
Inflammatory serum cytokines and chemokines increase associated with the disease extent in pediatric Langerhans cell histiocytosis
Keywords: CCL; CC-chemokine ligand; CCR; CC-chemokine receptor; CXCL; CXC-chemokine ligand; ECD; Erdheim-Chester disease; FGF; fibroblast growth factor; G-CSF; granulocyte colony-stimulating factor; GM-CSF; granulocyte-macrophage colony-stimulating factor; HGF; h
Oral administration with diosgenin enhances the induction of intestinal T helper 1-like regulatory T cells in a murine model of food allergy
Keywords: CCL; chemokine (C-C motif) ligand; CCR; C-C chemokine receptor; CXCL; chemokine (C-X-C motif) ligand; CXCR; C-X-C chemokine receptor; Foxp3; forkhead box P3; IFN; interferon; Ig; immunoglobulin; IHC; immunohistochemical; IL; interleukin; OVA; ovalbumin; R
The good and the bad faces of STAT1 in solid tumours
Keywords: BAD; Bcl2-associated agonist of cell death; Bcl; B-cell lymphoma; CD; cluster of differentiation; CDK; cyclin-dependent kinase; CTL; cytotoxic T lymphocyte; CUG; cancer upregulated gene; CXCL; C-X-C motive ligand; DC; dendritic cells; DAMP; danger-associa
Compatibility of Tanshinone IIA and Astragaloside IV in attenuating hypoxia-induced cardiomyocytes injury
Keywords: AMI; Acute myocardial infarction; AsIV; Astragaloside IV; CCL; Chemokine (C-C motif) ligand; CXCL; Chemokine (C-X-C motif) ligand; DAPI; 40,6-diamidino-2-phenylindole; DMEM; Dulbecco's Modified Eagle Medium; ECL; Chemiluminescent autoradiography; ELISA; E
Palladium and Platinum Nanoparticles Activate AHR and NRF2 in Human Keratinocytes-Implications in Vitiligo Therapy
Keywords: AHR; aryl hydrocarbon receptor; CYP1A1; cytochrome P450 family 1 subfamily A member 1; CXCL; chemokine (C-X-C motif) ligand; NHEK; normal human epidermal keratinocyte; NRF2; nuclear factor (erythroid-derived 2)-like 2; NQO1; NAD(P)H quinone dehydrogen
Effect of PPAR-β/δ agonist GW0742 treatment in the acute phase response and blood-brain barrier permeability following brain injury
Keywords: APR; acute phase response; BBB; blood-brain barrier; CBF; cerebral blood flow; CCR; chemokine receptors; CNS; central nervous system; CXCL; chemokine (C-X-C motif) ligand; DAB; diaminobenzidine; EB; Evans Blue; GAPDH; glyceraldehyde 3-phosphate dehydrog
DHA-derived oxylipins, neuroprostanes and protectins, differentially and dose-dependently modulate the inflammatory response in human macrophages: Putative mechanisms through PPAR activation
Keywords: AP-1; activator protein 1; B94, TNFAIP2; TNF alpha induced protein 2; C/EBP; CCAAT-enhancer-binding protein; CCL; chemokine ligand; CEX-1; chemokine exodus protein 1; COX; cyclooxygenase; CXCL; chemokine (C-X-C motif) ligand; CYP; cytochrome P450 monooxyg
Semaphorin4D Drives CD8+ T-Cell Lesional Trafficking in Oral Lichen Planus via CXCL9/CXCL10 Upregulations in Oral Keratinocytes
Keywords: AKT; protein kinase B; CCL; C-C motif chemokine ligand; CXCL; C-X-C motif chemokine ligand; MIG; monokine induced by interferon-gamma; MMP; matrix metalloproteinase; OLP; oral lichen planus; OSF; oral submucous fibrosis; PBMC; peripheral blood mononuclear
Airway Goblet Cells Secrete Pro-Inflammatory Cytokines, Chemokines, and Growth Factors
Keywords: airway inflammation; allergic asthma; asthma; cilia; immunology asthma; ALI; air-liquid interface; bFGF; basic fibroblast growth factor; CCL; cysteine-cysteine motif chemokine; CXCL; cysteine-X-cysteine chemokine; MIP; macrophage inflammatory protein; NHB
Human herpesvirus 8-encoded chemokine vCCL2/vMIP-II is an agonist of the atypical chemokine receptor ACKR3/CXCR7
Keywords: ACKR; atypical chemokine receptor; CCKAR; cholecystokinin A receptor; CCL; chemokine (CC motif) ligand; CHO; Chinese hamster ovary; CXCL; chemokine (CXC motif) ligand; CX3CL; chemokine (CX3C motif) ligand; EBV; Epstein-Barr virus; ERK; extracellular rec
Kinetics of chemotaxis, cytokine, and chemokine release of NR8383 macrophages after exposure to inflammatory and inert granular insoluble particles
Keywords: BET; brunauer, emmett, teller; CCL; chemokine (C-C motif) ligand; CXCL; chemokine (C-X-C motif) ligand; dHL-60; differentiated human leukemia cells; DLS; dynamic light scattering; FCS; fetal calf serum; IC50; half maximal inhibitory concentration; PBS; ph
Full Length ArticleExpression of pro-inflammatory genes in human endothelial cells: Comparison of rivaroxaban and dabigatran
Keywords: ACTB; cytosolic β-actin; APC; activated protein C; B2M; β-2-microglobulin; CXCL; chemokine (C-X-C motif) ligand; MCP; chemokine (C-C motif) ligand; DMSO; dimethyl sulfoxide; ELAM; endothelial leukocyte adhesion molecule; EBM; endothelial cell basal medi
Mini reviewA gradient of glucocorticoid sensitivity among helper T cell cytokines
Keywords: ADAM17; ADAM Metallopeptidase Domain 17; ADH; alcohol dehydrogenase; AHR; aryl hydrocarbon receptor; AP-1; activator protein 1; BCL; B-cell lymphoma; BIM; Bcl-2 interacting mediator of cell death; CBP; CREB-binding protein; CCL; CC chemokine ligands; CXCL
Hepatocyte Toll-Like Receptor 5 Promotes Bacterial Clearance and Protects Mice Against High-Fat Diet-Induced Liver Disease
Keywords: Innate Immunity; TLR5; Hepatocytes; Inflammation; Steatosis; ALT; alanine aminotransferase; AST; aspartate aminotransferase; CCL4; carbon tetrachloride; CFU; colony-forming unit; ConA; concanavalin A; CXCL; chemokine (C-X-C motif) ligand 1; DC; dendritic
ReviewOpioid-induced hyperalgesia: Cellular and molecular mechanisms
Keywords: 5-HT; serotonin; β2-AR; β2-adrenergic receptor; β-FNA; β-funaltrexamine; BDNF; brain derived neurotrophic factor; CCK; cholecystokinin; CNS; central nervous system; CxCR; chemokine receptor; CxCL; chemokine; DAMGO; Tyr-D-Ala-Gly-NMe-Phe-Gly-ol; DOR; d
The Paracaspase MALT1
Keywords: NF-κB signaling; Protease; Caspase; Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1); ABC; activated B cell-like; ABC-DLBCL; activated B cell-like diffuse large B cell lymphoma; Ac; acetyl; ALL; acute lymphomblastic leukemia; AM
Microenvironment interactions and B-cell receptor signaling in Chronic Lymphocytic Leukemia: Implications for disease pathogenesis and treatment
Keywords: APRIL; a proliferation-inducing ligand; ATM; ataxia telangiectasia mutated; BAFF; B-cell activating factor; BAFFR; BAFF receptor; BAG6; BCL2-associated athanogene 6; BCMA; B-cell maturation antigen; BCL2; B-cell lymphoma 2; BCR; B cell receptor; bFGF; bas
Molecular and cellular mechanisms linking inflammation to insulin resistance and β-cell dysfunction
Keywords: AMPK; AMP-activated protein kinase; ATM; adipose tissue macrophages; CCL; chemokine (C-C motif) ligand; CCR2; chemokine (C-C motif) receptor 2; CX3CL1; chemokine (C-X3-C motif) ligand 1; CX3CR1; chemokine (C-X3-C motif) receptor; CXCL; CXC chemokine ligan
Interferons as components of the complex web of reactions sustaining inflammation in idiopathic inflammatory myopathies
Keywords: BAFF; B lymphocyte Activation factor; CCL; α-chemokine; CXCL; β-chemokine; DC; dendritic cell; DM; dermatomyositis; IBM; sporadic inclusion body myositis; IFNAR; type 1 IFN receptor; IFNGR; type 2 IFN receptor; IFNLR; type 3 IFN receptor; IM; idiopathic
Particle-induced cell migration assay (PICMA): A new in vitro assay for inflammatory particle effects based on permanent cell lines
Keywords: CCL2; chemokine (C-C motif) ligand 2; CD; cluster of differentiation; COPD; chronic obstructive pulmonary disease; CXCL; chemokine (C-X-C motif) ligand; dHL-60 cells; differentiated human leukemia-60 cells; DLS; dynamic light scattering; EDX; energy
Targeting human CD2 by the monoclonal antibody CB.219 reduces intestinal inflammation in a humanized transfer colitis model
Keywords: CCL; CC chemokine ligand; CXCL; CXC-motif ligand; FoxP3; forkhead box protein 3; hpf; high power field; huCD2tg; mice expressing human CD2; IBD; inflammatory bowel diseases; IFNγ; interferon γ; Ig; immunoglobulin; IL; interleukin; LPL; lamina propria ly
Conditioning solid tumor microenvironment through inflammatory chemokines and S100 family proteins
Keywords: CXCL; chemokine (C-X-C motif) ligand; CCL; chemokine (C-C motif) ligand; XCL1; chemokine (C motif) ligand; CXCR; chemokine (C-X-C motif) receptor; CCR; chemokine (C-C) motif receptor; RANTES; regulated on activation normal T cell expressed and
Successful Interferon-Free Therapy of Chronic Hepatitis C Virus Infection Normalizes Natural Killer Cell Function
Keywords: Immune Regulation; NS5A Inhibitor; NS3 Inhibitor; ISG; APC; allophycocyanin; ASV; asunaprevir; CXCL; chemokine C-X-C motif ligand; DAA; direct-acting antiviral; DCV; daclatasvir; EMA; ethidium monoazide; EOT; end of treatment; FBS; fetal bovine serum; FIT