Keywords: مهار کننده کیناز وابسته به سیکلین; 17-AAG; 17-(Allylamino)-17-demethoxygeldanamycin; 17-DMAG; 17-Dimethylaminoethylamino-17-demethoxygeldanamycin; AKT; v-akt murine thymoma viral oncogene homolog; APC; antigen presenting cell; ATM; Ataxia telangiectasia mutated; ATR; Ataxia telangiectasia
مقالات ISI مهار کننده کیناز وابسته به سیکلین (ترجمه نشده)
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Keywords: مهار کننده کیناز وابسته به سیکلین; ABC; ATP binding cassette; ADR; adverse drug reactions; ALA; alpha-linolenic acid; ALT; alanine aminotransferase; CVD; cardiovascular disease; AUC; area under the concentration-time curve; Cmax; maximal plasma concentration; CYP; cytochrome P; EGCG; epi
Keywords: مهار کننده کیناز وابسته به سیکلین; B2M; beta 2 microglobulin; CAR; cyclophophamide, alvocidib, rituximab; CDK; cyclin-dependent kinase; CLL; chronic lymphocytic leukemia; CR; complete response; CRS; cytokine release syndrome; DLT; dose limiting toxicity; ECOG; Eastern Cooperative Oncology
Keywords: مهار کننده کیناز وابسته به سیکلین; APC/C; anaphase-promoting complex/cyclosome; BM; bone marrow; CDK; cyclin-dependent kinase; CKI; cyclin-dependent kinase inhibitor; CXCL12; chemokine (C-X-C motif) ligand 12; HSC; hematopoietic stem cell; Hsc70; heat shock cognate protein 70; LAP; latency
Synthesis of 4,6-disubstituted pyrazolo[3,4-d]pyrimidine analogues: Cyclin-dependent kinase 2 (CDK2) inhibition, molecular docking and anticancer evaluation
Keywords: مهار کننده کیناز وابسته به سیکلین; Pyrazolo[3,4-d]pyrimidine; Cyclin-dependent kinase inhibitor; Anti-proliferative activity; Molecular docking; GLIDE;
Prohibitin-2 is a novel regulator of p21WAF1/CIP1 induced by depletion of γ-glutamylcyclotransferase
Keywords: مهار کننده کیناز وابسته به سیکلین; Gamma-glutamylcyclotransferase; p21WAF1/CIP1; Prohibitin-2; Protein-protein interaction; Cell cycle arrest; Cellular senescence; GGCT; gamma-glutamylcyclotransferase; p21; p21WAF1/CIP1; CDKI; cyclin-dependent kinase inhibitor; PHB; Prohibitin; ER; Estroge
Targeting CD26 suppresses proliferation of malignant mesothelioma cell via downmodulation of ubiquitin-specific protease 22
Keywords: مهار کننده کیناز وابسته به سیکلین; CD26; Ubiquitin-specific protease 22; Malignant pleural mesothelioma; Humanized anti-CD26 monoclonal antibody; CD26si; siRNA against CD26; CSC; cancer stem cell; Csh; control shRNA; Csi; control siRNA; CDKI; cyclin-dependent kinase inhibitor; HuCD26mAb; h
LC-MS/MS method for determination of cyclin-dependent kinase inhibitors, BP-14 and BP-20, and its application in pharmacokinetic study in rat
Keywords: مهار کننده کیناز وابسته به سیکلین; Cyclin-dependent kinase inhibitor; BP-14; BP-20; Pharmacokinetics; Tissue distribution;
Ribociclib shows potential for pharmacokinetic drug-drug interactions being a substrate of ABCB1 and potent inhibitor of ABCB1, ABCG2 and CYP450 isoforms in vitro
Keywords: مهار کننده کیناز وابسته به سیکلین; 95%CI; 95% confidential interval; AB; apical-to-basolateral; ABC; ATP-binding cassette; Abcb1; canine P-glycoprotein; ABCB1; human P-glycoprotein; ABCC1; multidrug resistance-associated protein 1; ABCG2; breast cancer resistance protein; BA; basolateral-t
Coordinated d-cyclin/Foxd1 activation drives mitogenic activity of the Sonic Hedgehog signaling pathway
Keywords: مهار کننده کیناز وابسته به سیکلین; Sonic Hedgehog signaling; Cell proliferation; Cyclins; Cyclin-dependent kinase inhibitor; Forkhead box;
Agastache rugosa Kuntze extract, containing the active component rosmarinic acid, prevents atherosclerosis through up-regulation of the cyclin-dependent kinase inhibitors p21WAF1/CIP1 and p27KIP1
Keywords: مهار کننده کیناز وابسته به سیکلین; AKT; phosphatidylinositol 3-kinase-linked protein kinase; A.rugose; Agastacherugosa Kuntze; BrdU; bromodeoxyuridine; CA; caffeic acid; CCK-8; cell counting Kit-8; CDK; cyclin-dependent kinase; CKI; cyclin-dependent kinase inhibitor; DAD; diode array UV/VI
Mini-reviewp27Kip1 and human cancers: A reappraisal of a still enigmatic protein
Keywords: مهار کننده کیناز وابسته به سیکلین; p27Kip1; Cyclin-dependent kinase inhibitor; Human cancers; Multiple endocrine neoplasia; Endocrine tumors; Hairy cell leukemia;
G protein-coupled receptor kinase 4-induced cellular senescence and its senescence-associated gene expression profiling
Keywords: مهار کننده کیناز وابسته به سیکلین; GPCR; G protein-coupled receptor; GRK; G protein-coupled receptor kinases; SA-β-Gal; senescence-associated-β-galactosidase; FACS; fluorescence-activated cell sorting; CCK-8; cell counting kit-8; CDK; cyclin-dependent kinase; CKI; cyclin-dependent kinase
Alteration of canonical and non-canonical WNT-signaling by crystalline silica in human lung epithelial cells
Keywords: مهار کننده کیناز وابسته به سیکلین; ACTA2; Actin, alpha, smooth muscle; ANGPTL4; Angiopoietin-like 4; ANOVA; Analysis of variance; AXIN; Axis inhibition protein; BMP; Bone morphogenic protein; BMPR1B; BMP receptor 1B; CACNA2D3; Calcium channel, voltage-dependent, alpha 2/delta subunit 3; CC
Upregulation of cyclin-dependent kinase inhibitors CDKN1B and CDKN1C in hepatocellular carcinoma-derived cells via goniothalamin-mediated protein stabilization and epigenetic modifications
Keywords: مهار کننده کیناز وابسته به سیکلین; Cyclin-dependent kinase inhibitor; CKI; Goniothalamin; Cell cycle; Hepatocellular carcinoma-derived cells; Epigenetic modification
Loss of p27 phosphorylation at Ser10 accelerates early atherogenesis by promoting leukocyte recruitment via RhoA/ROCK
Keywords: مهار کننده کیناز وابسته به سیکلین; apoEâ/â; apolipoprotein E-null; apoEâ/âp27Ser10Ala; apolipoprotein E-null p27 Serine-10-Alanine; BM; bone marrow; CKI; cyclin-dependent kinase inhibitor; DMEM; Dulbecco's modified eagle medium; EC(s); endothelial cell(s); ECGS; endothelial cell gr
Liver maturation deficiency in p57Kip2â/â mice occurs in a hepatocytic p57Kip2 expression-independent manner
Keywords: مهار کننده کیناز وابسته به سیکلین; Afp; α-fetoprotein; Bmp; bone morphogenic proteins; C/EBPα; CCAAT/enhancer-binding protein α; CK; cytokeratin; CKI; cyclin-dependent kinase inhibitor; Cyp; cytochrome P450; DAPI; 4â²,6-diamidino-2-phenylindole dihydrochloride; Dlk1; delta-like 1 homol
Liquid chromatography-tandem mass spectrometric assay for the cyclin-dependent kinase inhibitor AT7519 in mouse plasma
Keywords: مهار کننده کیناز وابسته به سیکلین; AUC0ââ; area under the plasma concentration-time curve; CDK; cyclin-dependent kinase; Cmax; maximum plasma concentration; EDTA; ethylenediaminetetraacetic acid; i.p.; intraperitoneal; IS; internal standard; MYCN; V-myc myelocytomatosis viral related
Tetrahydrocurcumin induces G2/M cell cycle arrest and apoptosis involving p38 MAPK activation in human breast cancer cells
Keywords: مهار کننده کیناز وابسته به سیکلین; AO; acridine orange; cdc 2; cell division cycle 2; CDK; cyclin-dependent kinase; CDKI; cyclin-dependent kinase inhibitor; DMSO; dimethyl sulfoxide; ERK; extracellular signal-regulated kinase; FBS; fetal bovine serum; JNK; Jun N-terminal kinase; MAPK; mito
PPARγ1 phosphorylation enhances proliferation and drug resistance in human fibrosarcoma cells
Keywords: مهار کننده کیناز وابسته به سیکلین; PPARγ; peroxisome proliferator-activated receptor γ; PPRE; PPAR-response elements; CDK; cyclin-dependent kinase; CKI; cyclin-dependent kinase inhibitor; PCNA; proliferating cell nuclear antigen; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium
Sec6 regulated cytoplasmic translocation and degradation of p27 via interactions with Jab1 and Siah1
Keywords: مهار کننده کیناز وابسته به سیکلین; Rho GDIα; Rho GDP-dissociation inhibitor α; GFP; green fluorescence protein; BrdU; bromodeoxyuridine; 7-AAD; 7-amino-actinomycin D; CDK; cyclin-dependent kinase; CKI; cyclin-dependent kinase inhibitor; siRNA; small interfering RNA; Siah1; seven in absen
5-aza-2â²-deoxycytidine-mediated c-myc Down-regulation Triggers Telomere-dependent Senescence by Regulating Human Telomerase Reverse Transcriptase in Chronic Myeloid Leukemia
Keywords: مهار کننده کیناز وابسته به سیکلین; C12FDG; fluorogenic substrate 5-dodecanoylaminofluorescein di-β-D-galactopyranoside; CDKN; cyclin-dependent kinase inhibitor; ChIP; chromatin immunoprecipitation; CML; chronic myeloid leukemia; CTCF; CCCTC-binding factor; DAC; 5-aza-2'-deoxycytidine; D
ReviewMechanisms regulating the development of oligodendrocytes and central nervous system myelin
Keywords: مهار کننده کیناز وابسته به سیکلین; AN2/NG2; neural/glial antigen 2; BDNF; brain-derived neurotrophic factor; BMP; bone morphogenic protein; bHLH; basic helix-loop-helix; (PI3K)/PKC; phosphoinositide 3-kinase; PKA; protein kinase A; cdkn1c; cyclin-dependent kinase inhibitor; CDK5; cyclin-de
Fission yeast LAMMER kinase Lkh1 regulates the cell cycle by phosphorylating the CDK-inhibitor Rum1
Keywords: مهار کننده کیناز وابسته به سیکلین; Fission yeast; LAMMER kinase; Lkh1; Cyclin-dependent kinase inhibitor; Rum1; Phosphorylation;
Jaceosidin, isolated from dietary mugwort (Artemisia princeps), induces G2/M cell cycle arrest by inactivating cdc25C-cdc2 via ATM-Chk1/2 activation
Keywords: مهار کننده کیناز وابسته به سیکلین; ATM; atazia-telagiectasia mutated; Caspase; cystein aspartyl-specific protease; Cdc 2; cell division cycle 2; Cdk; cyclin-dependent kinase; CDKI; cyclin-dependent kinase inhibitor; ERK; extracellular signal-regulated kinase; MAPK; mitogen activated protei
Interferon-γ Activates Expression of p15 and p16 Regardless of 9p21.3 Coronary Artery Disease Risk Genotype
Keywords: مهار کننده کیناز وابسته به سیکلین; 9p21.3; coronary artery disease; cyclin-dependent kinase inhibitor; interferon-γ; p15; p16CAD, coronary artery disease; HAoSMC, human primary aortic smooth muscle cells; HUVEC, human umbilical vein endothelial cell; LCL, lymphoblastoid cell; PCR, polymera
Nuclear Expression of p27Kip1 Is Associated with In Vivo Differentiation of Adult Human Odontoblasts
Keywords: مهار کننده کیناز وابسته به سیکلین; Cyclin-dependent kinase inhibitor; dentin caries; differentiation; odontoblast; p27; preodontoblast; reparative dentin; stromal cell;
Vitamin D in thyroid tumorigenesis and development
Keywords: مهار کننده کیناز وابسته به سیکلین; 1,25(OH)2D3; 1α,25-dihydroxyvitamin D3; 25-OHD3; 25-hydroxyvitamin D3; ATC; anaplastic thyroid cancer; CDK; cyclin-dependent kinase; CDKI; cyclin-dependent kinase inhibitor; CEA; carcinoembryogenic antigen; CT; calcitonin; CYP24A1; 24-hydroxylase; CYP27B
Synthesis and biological evaluation of benzo[d]imidazole derivatives as potential anti-cancer agents
Keywords: مهار کننده کیناز وابسته به سیکلین; RNA polymerase-II; Cyclin-dependent kinase inhibitor; Apoptosis; Anti-cancer therapy
Disruptive cell cycle regulation involving epigenetic downregulation of Cdkn2a (p16Ink4a) in early-stage liver tumor-promotion facilitating liver cell regeneration in rats
Keywords: مهار کننده کیناز وابسته به سیکلین; BNF; β-naphthoflavone; Cdc2; cell division cycle 2; Cdc25c; cell division cycle 25 homolog C (S. pombe); Cdk; cyclin-dependent kinase; Chk1; checkpoint kinase 1; CKI; cyclin-dependent kinase inhibitor; DEN; N-diethylnitrosamine; FB; fenbendazole; γH2AX;
Activation of the BRCA1/Chk1/p53/p21Cip1/Waf1 pathway by nitric oxide and cell cycle arrest in human neuroblastoma NB69 cells
Keywords: مهار کننده کیناز وابسته به سیکلین; AEBSF; 4-(2-aminoethyl)-benzenesulfonyl fluoride; ATM; ataxia telangiectasia mutated; ATR; AT- and Rad3-related; BRCA1; breast cancer susceptibility protein-1; CDKI; cyclin-dependent kinase inhibitor; DAF-DA; 4,5-diaminofluorescein diacetate; Cdk; cyclin-
Molecular characterization and expression profiles of cdc2 and cyclin B during oogenesis and spermatogenesis in green mud crab (Scylla paramamosain)
Keywords: مهار کننده کیناز وابسته به سیکلین; BCIP; (5-bromo-4-chloro-1H-indol-3-yl) dihydrogen phosphate; BSA; bovine serum albumin; CDC; cell division cycle; CDK; cyclin-dependent kinase; CKI; cyclin-dependent kinase inhibitor; GSI; gonadosomatic index; GVBD; germinal vesicle breakdown; MPF; matura
hCLP46 regulates U937 cell proliferation via Notch signaling pathway
Keywords: مهار کننده کیناز وابسته به سیکلین; hCLP46; human CAP10-like protein 46Â kDa; Poglut; protein O-glucosyltransferase; Poglut1; protein O-glucosyltransferase1 (mammalian); CDKI; cyclin-dependent kinase inhibitor; CDKN1B (p27); cyclin-dependent kinase inhibitor 1B; RB; retinoblastoma; CSL; CBF
Pioglitazone promotes preadipocyte proliferation by downregulating p16Ink4a
Keywords: مهار کننده کیناز وابسته به سیکلین; BrdU; 5-bromo-2-deoxyuridine; CDK; cyclin dependent kinase; CDKI; cyclin dependent kinase inhibitor; DAPI; 4â²,6-diamidino-2-phenylindole; FACS; fluorescence-activated cell sorting; PPAR; peroxisome proliferator-activated receptor; T2DM; type 2 diabetes
Anticancer activity of a low immunogenic protein toxin (BMP1) from Indian toad (Bufo melanostictus, Schneider) skin extract
Keywords: مهار کننده کیناز وابسته به سیکلین; Common Indian toad; Bufo melanostictus; BMP1; Anti-proliferative; Apoptogenic; CDK; Low immunogenic protein; AO; acridine orange; BMP1; Bufo melanostictus protein 1; CDKI; cyclin-dependent kinase inhibitor; DAPI; 4â²,6-diamidino-2-phenylindole; EAC; Ehrl
B lymphocyte proliferation is suppressed by the opioid growth factor–opioid growth factor receptor axis: Implication for the treatment of autoimmune diseases
Keywords: مهار کننده کیناز وابسته به سیکلین; Cell proliferation; Cyclin-dependent kinase inhibitor; [Met5]-enkephalin; Opioid growth factor; OGFr; T lymphocyte
Imaging Bone Morphogenetic Protein 7 Induced Cell Cycle Arrest in Experimental Gliomas
Keywords: مهار کننده کیناز وابسته به سیکلین; BMP; bone morphogenetic protein; Cdk; cyclin-dependent kinase; CdkI; cyclin-dependent kinase inhibitor; LITG; firefly luciferase-IRES-tkgfp; Rb; retinoblastoma protein;
Activin A, p15INK4b Signaling, and Cell Competition Promote Stem/Progenitor Cell Repopulation of Livers in Aging Rats
Keywords: مهار کننده کیناز وابسته به سیکلین; p16INK4a; p19ARF; p21/CIP1; Stem Cell Therapy; cdk; cyclin-dependent kinase; CKI; cyclin-dependent kinase inhibitor; FLSPC; fetal liver stem/progenitor cell; mRNA; messenger RNA; PH; partial hepatectomy; TGF-β; transforming growth factor-β;
Linalool preferentially induces robust apoptosis of a variety of leukemia cells via upregulating p53 and cyclin-dependent kinase inhibitors
Keywords: مهار کننده کیناز وابسته به سیکلین; Linalool; Leukemia; Apoptosis; p53 tumor suppressor; Cyclin-dependent kinase inhibitor
Indole-3-carbinol induces apoptosis through p53 and activation of caspase-8 pathway in lung cancer A549 cells
Keywords: مهار کننده کیناز وابسته به سیکلین; CDKI; cyclin-dependent kinase inhibitor; I3C; indole-3-carbinol; PARP; poly (ADP-ribose) polymerase; PI3K; phosphatidylinositol 3-kinase; z-IETD-FMK; benzyloxycarbonyl-Ile-Glu (OMe)-Thr-Asp (OMe)-fluoromethyl ketone; Indole-3-carbinol; Lung cancer; A549;
Recent developments in cyclin-dependent kinase biochemical and structural studies
Keywords: مهار کننده کیناز وابسته به سیکلین; CDK; cyclin-dependent kinase; CKI; cyclin-dependent kinase inhibitor; T160pCDK2/cyclinA; CDK2 phosphorylated on Thr160 bound to cyclinA; Y15pT160pCDK2/cyclinA; CDK2 phosphorylated on Tyr15 and on Thr160 bound to cyclinA; CBF; cyclin box fold; CDK; Cyclin;
Efficacy of lanreotide in preventing the occurrence of chemically induced hepatocellular carcinoma in rats
Keywords: مهار کننده کیناز وابسته به سیکلین; AAF; acetylaminofluorene; ALT; alanine aminotransferase; CdK; cyclin-dependent kinase; CKi; cyclin-dependent kinase inhibitor; CTL; control; CYP; cytochrome p450; DEN; diethylnitrosamine; FAH; foci of altered hepatocytes; GSTp; glutathione S-transferase o
Cell cycle regulation in the inner ear sensory epithelia: Role of cyclin D1 and cyclin-dependent kinase inhibitors
Keywords: مهار کننده کیناز وابسته به سیکلین; Inner ear; Hair cell; Supporting cell; Postmitotic; Cell cycle re-entry; Proliferation; Therapy; Cyclin D1; Cyclin-dependent kinase inhibitor; β-catenin;
Acute renal failure during sepsis: Potential role of cell cycle regulation
Keywords: مهار کننده کیناز وابسته به سیکلین; Renal failure; Acute; Cyclin; Cyclin-dependent kinase; Cyclin-dependent kinase inhibitor
Silencing p27 reverses post-mitotic state of supporting cells in neonatal mouse cochleae
Keywords: مهار کننده کیناز وابسته به سیکلین; RNA interference; Cyclin-dependent kinase inhibitor; Cochlea; Mitosis; Apoptosis; Regeneration
Cancer cell iron metabolism and the development of potent iron chelators as anti-tumour agents
Keywords: مهار کننده کیناز وابسته به سیکلین; 311; 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone; BpT; 2-benzoylpyridine thiosemicarbazone; CDK; cyclin-dependent kinase; CDKi; cyclin-dependent kinase inhibitor; DFO; desferrioxamine; DMT1; divalent metal ion transporter 1; DpT; di-2-pyridylketo
Mutational analysis of CDKN1B, a candidate tumor-suppressor gene, in refractory secondary/tertiary hyperparathyroidism
Keywords: مهار کننده کیناز وابسته به سیکلین; p27; p27Kip1; cyclin-dependent kinase inhibitor; parathyroid neoplasia; parathyroid hormone; secondary/tertiary hyperparathyroidism
Pyrogallol inhibits the growth of human lung cancer Calu-6 cells via arresting the cell cycle arrest
Keywords: مهار کننده کیناز وابسته به سیکلین; PG; pyrogallol; ROS; reactive oxygen species; FBS; fetal bovine serum; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; PI; propidium iodide; CDK; cyclin-dependent kinase; DHE; dihydroethidium; CDKI; cyclin-dependent kinase inhibitor; NA
Design, synthesis, and evaluation of 3,4-disubstituted pyrazole analogues as anti-tumor CDK inhibitors
Keywords: مهار کننده کیناز وابسته به سیکلین; Pyrazole analogues; Cyclin-dependent kinase inhibitor; Anti-tumor agents; Anti-proliferative agents
Cytoplasmic localization and ubiquitination of p21Cip1 by reactive oxygen species
Keywords: مهار کننده کیناز وابسته به سیکلین; Nuclear export; Ubiquitination; Degradation; Reactive oxygen species; Cyclin-dependent kinase inhibitor