دانلود مقالات ISI درباره CYP + ترجمه فارسی

Telaprevir is a substrate and moderate inhibitor of P-glycoprotein, a strong inductor of ABCG2, but not an activator of PXR in vitro

Keywords: CYP; Telaprevir; Drug transporters; CYPs; PXR; Interaction

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Inhibitory activity of sesaminol and sesaminol triglycoside on cytochrome P450 enzymes and their pharmacokinetics in rats

Keywords: CYP; STG; sesaminol triglycoside; CYPs; cytochrome P450; Cmax; the maximum plasma concentration; Tmax; the time to reach maximum plasma concentration; t1/2; the half-lives; AUC; the area under the drug concentration-time curve; Cl; clearance; Vd; volume of d

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Expression and methylation status of female-predominant GH-dependent liver genes are modified by neonatal androgenization in female mice

Keywords: CYP; GH; Liver; Cyps; Neonatal testosterone; Sexual differences; DNA methylation;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

The involvement of Nrf2 in the protective effects of diallyl disulfide on carbon tetrachloride-induced hepatic oxidative damage and inflammatory response in rats

Keywords: CYP; ALT; alanine aminotransferase; ANOVA; analysis of variance; ARE; antioxidant response element; AST; aspartate aminotransferase; Bax; Bcl-2-associated X; CCl4; carbon tetrachloride; Cox-2; cyclooxygenase-2; CYPs; cytochrome P450 isoenzymes; DADS; diallyl d

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Transport of estradiol-17β-glucuronide, estrone-3-sulfate and taurocholate across the endoplasmic reticulum membrane: evidence for different transport systems

Keywords: CYP; ABC; ATP binding cassette; CYPs; cytochrome P450s; DHEAS; dehydroepiandrosteronesulfate; ER; endoplasmic reticulum; E17βG; estradiol-17β-glucuronide; E3S; estrone-3-sulfate; G6P; glucose-6-phosphate; HPTLC; high performance thin layer chromatography; MR

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Sustained expression of CYPs and DNA adduct accumulation with continuous exposure to PCB126 and PCB153 through a new delivery method: Polymeric implants

Keywords: CYP; Polychlorinated biphenyls (PCBs); PCB126 (3,3′,4,4′,5-pentachlorobiphenyl); PCB153 (2,2′,4,4′,5,5′-hexachlorobiphenyl); Polymeric implants; DNA adducts; 32P-postlabeling; CYPs; Paraoxonase 1 (PON1)

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

The crab Carcinus maenas as a suitable experimental model in ecotoxicology

Keywords: CYP; 6PGDH; 6-phosphogluconate dehydrogenase; AChE; acetylcholinesterase; AWP; apparent water permeability; BChE; butyrylcholinesterase; BP; benzopyrene; BPH; benzopyrene hydroxylase; BPMO; benzopyrene monoxygenase; BRI; Biomarker Response Index; CAT; catalase

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2014 سفارش ترجمه

Plant flavonol isorhamnetin attenuates chemically induced inflammatory bowel disease via a PXR-dependent pathway

Keywords: CYP; CD; Crohn's disease; COX2; cyclooxygenase 2; CYPs; cytochromes P450; DSS; dextran sodium sulfate; ELISA; enzyme linked immunosorbent assay; GSTs; glutathione S-transferases; IBD; inflammatory bowel disease; ICAM-1; Intercellular adhesion molecule-1; IL-2/

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2014 سفارش ترجمه

Induction of cytochrome P450 enzymes in primary equine hepatocyte culture

Keywords: CYP; FBS; fetal bovine serum; CYPs; cytochrome P450 enzymes; HBSS; Hanks' balanced salt solution; HTK; histidine-tryptophan-ketoglutarate; WEM; Williams' medium E; DMEM; Dulbecco's Modified Eagle Medium; DMSO; dimethyl-sulphoxide; EGTA; ethylene glycol t

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Posttranslational mechanisms modulating the expression of the cytochrome P450 1A1 gene by methylmercury in HepG2 cells: A role of heme oxygenase-1

Keywords: CYP; AhR; aryl hydrocarbon receptor; MeHg; methyl mercury chloride; CYPs; cytochrome P450s; HO-1; heme oxygenase-1; TCDD; 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD); XRE; xenobiotic responsive element; ARE; antioxidant responsive element; SnMP; Tin mesoporphyr

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

FKBP52 is involved in the regulation of SOCE channels in the human platelets and MEG 01 cells

Keywords: CYP; Cyps; cyclophilins; FKBPs; immunophilin; FKBP52; FK506 binding protein (52); ER; rough endoplasmic reticulum; SERCA2b; sarco-endoplasmic Ca2 +-ATPase isotype 2b; IP3R II; inositol 1,4,5-trisphosphate receptor; TRPC; transient receptor potential channel;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Comparative xenobiotic metabolism capacities and pesticide sensitivity in adults of Solea solea and Solea senegalensis

Keywords: CYP; Benthic fish; Fluorometric substrates; CYPs; Carboxylesterases; Phase II enzymes; Pesticides

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Similarities in lindane induced alteration in cytochrome P450s and associated signaling events in peripheral blood lymphocytes and brain

Keywords: CYP; Lindane; CYPs; Lymphocytes; MAP kinases; Toxicity

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Beetroot juice protects against N-nitrosodiethylamine-induced liver injury in rats

Keywords: CYP; ALP; alkaline phosphatase; ALT; alanine aminotransferase; AST; aspartate aminotransferase; BUN; blood urea nitrogen; CDNB; 1-chloro-2,4-dinitrobenzene; CYPs; cytochromes P450; DPIP; 2,6-dichlorophenolindophenol; EROD; ethoxyresorufin-O-deethylase; GGT; ga

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Neonatal xenoestrogen exposure alters growth hormone-dependent liver proteins and genes in adult female rats

Keywords: CYP; ADH; alcohol dehydrogenase; AU; arbitrary units; BPA; bisphenol A; CIS; cytokine-inducible SH2-containing protein; CYP; cytochrome P450; Cyp2c11; cytochrome P450 gene 2C11; Cyp2c12; cytochrome P450 gene 2C12; GAPDH; glyceraldehyde 3-phosphate dehydrogenas

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Characterization of type “B” esterases and hepatic CYP450 isoenzimes in Senegalese sole for their further application in monitoring studies

Keywords: CYP; Characterization; Cholinesterases; Carboxylesterases Solea senegalensis; CYPs; Fluorimetric substrates

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Anti-inflammatory effect and modulation of cytochrome P450 activities by Artemisia annua tea infusions in human intestinal Caco-2 cells

Keywords: CYP; Artemisia annua; Artemisinin; Caco-2 cells; CYPs; Intestinal inflammation; Phenolic compounds; Rosmarinic acid;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Gene expression profiling and pathway network analysis of hepatic metabolic enzymes targeted by baicalein

Keywords: CYP; AKR1C1/2/3; aldo-keto reductase family 1, member C1/2/3; ALDH1L2; aldehyde dehydrogenase 1 family, member L2; ARE; antioxidant response element; CYPs; cytochrome P450 superfamily; DUSP1; dual specificity protein phosphatase 1; GCLC/M; glutamate cysteine l

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Mouse FKBP23 mediates conformer-specific functions of BiP by catalyzing Pro117cis/trans isomerization

Keywords: CYP; mBiP; mouse immunoglobulin binding protein; ER; endoplasmic reticulum; CyPs; cyclophilins; mFKBP; mouse FK506-binding protein; PPIase; peptidyl-prolyl cis/trans isomerase; Hsp; heat shock protein; mFKBP23N; N-terminus of mFKBP23; mBiPN; N-terminus of mBiP

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Time-course activities of Oct1, Mrp3, and cytochrome P450s in cultures of cryopreserved rat hepatocytes

Keywords: CYP; Hepatocyte cultures; Transport proteins; Oct1; Mrp3; CYPs; Functional activity

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Report from the EPAA workshop: In vitro ADME in safety testing used by EPAA industry sectors

Keywords: CYP; ADME; absorption, distribution, metabolism, and excretion; ADI; Acceptable Daily Intake; Colipa; the European Cosmetic Toiletry and Perfumery Association; CYPs; cytochrome P450s; DNEL; Derived No Effect Level; DG; Directorate General; ECHA; EU Chemicals A

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2011 سفارش ترجمه

Old and new generation lipid mediators in acute inflammation and resolution

Keywords: CYP; 5-HT; 5-hydroxytryptamine; HETEs; hydroxyeicosatetraenoic acids; 5-HEDH; 5-hydroxyeicosanoid dehydrogenase; 5(S)-HPETE; hydroperoxyeicosatetranoic acid; 15R-HETE; 15-R-hydroxyeicosatetraenoic acid; 17R-HDHA; 17R-hydroxydocosahexaenoic acid; AA; arachidoni

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2011 سفارش ترجمه

Long-term dose-dependent response of Mequindox on aldosterone, corticosterone and five steroidogenic enzyme mRNAs in the adrenal of male rats

Keywords: CYP; Mequindox; Aldosterone; Corticosterone; CYPs; Adrenal;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

The CYPome (Cytochrome P450 complement) of Aspergillus nidulans

Keywords: CYP; Cytochrome P450; CYPs; Haem-containing mono-oxygenases; Aspergillus nidulans

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Oxidative demethylenation and subsequent glucuronidation are the major metabolic pathways of berberine in rats

Keywords: CYP; BBR; pharmacokinetics; metabolic clearance; microsomes; enzyme kinetics; CYPs; UGTs;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Hybrid homology modeling and mutational analysis of cytochrome P450C24A1 (CYP24A1) of the Vitamin D pathway: Insights into substrate specificity and membrane bound structure–function

Keywords: CYP; Vitamin D; Calcitriol; 25-hydroxyvitamin D3 24R-hydroxylase; 1,25-dihydroxyvitamin D3; Vitamin D inactivation; Cytochrome P450; CYPs; P450C24A1; CYP24A1; Site-directed mutagenesis; Homology modeling; Affinity labeling; Monotopic membrane protein

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2007 سفارش ترجمه

Keratinocyte serum-free medium maintains long-term liver gene expression and function in cultured rat hepatocytes by preventing the loss of liver-enriched transcription factors

Keywords: CYP; W; Williams' medium E; KSFM; keratinocyte serum-free medium; Dex; dexamethasone; EGF or E; human epidermal growth factor; PGE or P; pituitary gland extract; C/EBP; CCAAT/enhancer-binding protein; HNF; hepatocyte nuclear factor; RXR; retinoid X receptor;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2007 سفارش ترجمه

Effects of genetic polymorphisms CYP1A1, GSTM1, GSTT1 and GSTP1 on urinary 1-hydroxypyrene levels in sugarcane workers

Keywords: CYP; Sugarcane workers; 1-Hydroxypyrene (1-OHP); Genetic polymorphisms; Polycyclic aromatic hydrocarbons (PAHs); CYPs; GSTs

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Effect of prenatal exposure of deltamethrin on the ontogeny of xenobiotic metabolizing cytochrome P450s in the brain and liver of offsprings

Keywords: CYP; Deltamethrin; In utero; Ontogeny; Brain; CYPs

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

Changes in cytochrome P450 isozymes (CYPs) protein levels during lactation in rat liver

Keywords: CYP; CYPs; F344 rat; Western blot analysis; Lactation;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2005 سفارش ترجمه

Effects of repeated administration with CP-55,940, a cannabinoid CB1 receptor agonist on the metabolism of the hepatic heme

Keywords: CYP; ALA-S; aminolevulinate synthase; CYPs; cytochrome P-450s; GSH; gluthation; HO; heme oxygenase; PBG-D; porphobilinogen deaminase; THC; Δ9-tetrahydrocannabinol; UROD; uroporphyrinogen decarboxylase; Cannabinoid CB1 receptor agonist CP-55,940; Hepatic porph

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

Effects of pregnancy on CYPs protein expression in rat liver

Keywords: CYP; CYPs; F344 rat; Immunohistochemistry; Pregnancy; Western blot analysis;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Chemoprevention of aflatoxicosis in poultry by dietary butylated hydroxytoluene

Keywords: CYP; AFB1; aflatoxin B1; AFBO; exo-aflatoxin B1-8,9-epoxide; BHA; butylated hydroxyanisole; BHT; butylated hydroxytoluene; BSA; bovine serum albumin; CDNB; 1-chloro-2,4-dinitrophenol; CYPs; cytochrome P450s; DCNB; 3,4-dichloronitrobenzene; DMSO; dimethylsulfox

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Disruption of microtubules leads to glucocorticoid receptor degradation in HeLa cell line

Keywords: CYP; AP-1; activator protein 1; BSA; bovine serum albumin; CAR; constitutive androstane receptor; COL; colchicine; CYPs; cytochromes P450; DEX; dexamethasone; DTT; dithiothreitol; GCs; glucocorticoids; GFP-GR; glucocorticoid receptor-green fluorescent protei

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

α-Tocopherol modulates Cyp3a expression, increases γ-CEHC production, and limits tissue γ-tocopherol accumulation in mice fed high γ-tocopherol diets

Keywords: CYP; α-TTP; α-tocopherol transfer protein; AVED; ataxia with vitamin E deficiency; CYPs; cytochrome P450s; α-CEHC; 2,5,7,8-tetramethyl-2-(2′-carboxyethyl)-6-hydroxychroman; γ-CEHC; 2,7,8-trimethyl-2-(2′carboxyethyl)-6-hydroxychroman; PBS; phosphate

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2005 سفارش ترجمه