کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6313726 | 1619058 | 2014 | 25 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The crab Carcinus maenas as a suitable experimental model in ecotoxicology
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کلمات کلیدی
G6PDHLT50LC50ERODDDTsHspethoxyresorufin-O-deethylaseLMSIBRIDHbutyrylcholinesteraseBChE6PGDHAWPDBFHexachlorocyclohexane isomersBiomarker response indexapparent water permeabilitydichlorodiphenyltrichloroethanesNADP+-dependent isocitrate dehydrogenaseGSIHSILPOGPXGSTGSHGSSGCATEC50CBE6-phosphogluconate dehydrogenase - 6-فسفوگلاوکونات دهیدروژنازCYPs - CYPHCHs - HCH هاHepatopancreas - hepatopancreascytochrome P450 enzymes - آنزیم های سیتوکروم P450AChE - آهیAcetylcholinesterase - استیل کولین استرازBRI - بریBenzopyrene - بنزوپیرنDAY - روزHour - ساعتHepatosomatic index - شاخص HepatosomaticCondition index - شاخص وضعیتgonadosomatic index - شاخص گنادوسوماتیکLDH - لاکتات دهیدروژناز به صورت مختصر شده LDH mean effective concentration - متوسط غلظت موثرHaemolymph - هموفیلیBPH - هیپرپلازی خوش خیم پروستات یا BPHIntegrated biomarker response - پاسخ بیومارکر یکپارچهLysosomal membrane stability - پایداری غشاء لیزوزومLipid peroxidation - پراکسیداسیون لیپیدStress proteins - پروتئین استرسCatalase - کاتالازreduced glutathione - کاهش گلوتاتیونcarboxylesterase - کربوکسی استرازCHE - کهCholinesterase - کولین استرازglutathione S-transferase - گلوتاتیون S-ترانسفرازoxidised glutathione - گلوتاتیون اکسید شدهglutathione reductase - گلوتاتیون ردوکتازglutathione peroxidase - گلوتاتیون پراکسیدازglucose-6-phosphate dehydrogenase - گلوکز 6-فسفات دهیدروژناز
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم محیط زیست
شیمی زیست محیطی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Aquatic ecotoxicology broadly focuses on how aquatic organisms interact with pollutants in their environment in order to determine environmental hazard and potential risks to humans. Research has produced increasing evidence on the pivotal role of aquatic invertebrates in the assessment of the impact of pollutants on the environment. Its potential use to replace fish bioassays, which offers ethical advantages, has already been widely studied. Nevertheless, the selection of adequate invertebrate experimental models, appropriate experimental designs and bioassays, as well as the control of potential confounding factors in toxicity testing are of major importance to obtain scientifically valid results. Therefore, the present study reviews more than four decades of published research papers in which the Green crab Carcinus maenas was used as an experimental test organism. In general, the surveyed literature indicates that C. maenas is sensitive to a wide range of aquatic pollutants and that its biological responses are linked to exposure concentrations or doses. Current scientific knowledge regarding the biology and ecology of C. maenas and the extensive studies on toxicology found for the present review recognise the Green crab as a reliable estuarine/marine model for routine testing in ecotoxicology research and environmental quality assessment, especially in what concerns the application of the biomarker approach. Data gathered provide valuable information for the selection of adequate and trustworthy bioassays to be used in C. maenas toxicity testing. Since the final expression of high quality testing is a reliable outcome, the present review recommends gender, size and morphotype separation in C. maenas experimental designs and data evaluation. Moreover, the organisms' nutritional status should be taken into account, especially in long-term studies. Studies should also consider the crabs' resilience when facing historical and concurrent contamination. Finally, experimental temperature and salinity should be harmonised so as to obtain reliable comparisons between different studies. Concerning future reaserch areas, data gathered in the present review reveals that in vitro assays derived from C. maenas are still lacking. Also, a complete C. maenas genome sequencing programme will be essencial for cutting-edge reseach.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Environment International - Volume 70, September 2014, Pages 158-182
Journal: Environment International - Volume 70, September 2014, Pages 158-182
نویسندگان
Elsa Teresa Rodrigues, Miguel Ãngelo Pardal,