Quantification of dopamine transporter density with [18F]FECNT PET in healthy humans
Keywords: Positron emission tomography; Dopamine transporter; Kinetic modeling; FECNT; DAT;
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Role of physiological mechanisms and EPSPS gene expression in glyphosate resistance in wild soybeans (Glycine soja)
Keywords: EPSPS; 5-enolpyruvylshikimate-3-phosphate synthase; GST; glutathione S-transferase; DAT; days after treatment; GR; glyphosate-resistant; GT; glyphosate treatment; R; resistant; S; susceptible; Glyphosate; Shikimic; Chlorophyll; GSTs; EPSPS mRNA levels;
Association of gene polymorphisms encoding dopaminergic system components and platelet MAO-B activity with alcohol dependence and alcohol dependence-related phenotypes
Keywords: MAO-B; monoamine oxidase type B; COMT; catechol-o-methyltransferase; DRD4; dopamine receptor D4; DAT; dopamine transporter; DBH; dopamine beta-hydroxylase; SNP; single nucleotide polymorphism; VNTR; variable number of tandem repeats; Alcohol dependence; A
Comparison of 99mTc-TRODAT-1 SPECT and 18 F-AV-133 PET imaging in healthy controls and Parkinson’s disease patients
Keywords: 18 F-AV-133; 99mTc-TRODAT-1; VMAT2; DAT; Parkinson's disease
H2O2- or l-DOPA-injured dopaminergic neurons trigger the release of soluble mediators that up-regulate striatal GDNF through different signalling pathways
Keywords: DA; dopaminergic; DAT; dopamine transporter; ECF; enhanced chemifluorescence; FBS; fetal bovine serum; FDU; 5-Fluorodeoxyuridine; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; GDNF; glial cell line-derived neurotrophic factor; IL; interleukin; IL-1ra;
Naloxone treatment alters gene expression in the mesolimbic reward system in 'junk food' exposed offspring in a sex-specific manner but does not affect food preferences in adulthood
Keywords: C; control diet; C-C; offspring exposed to a control diet before weaning and given saline injections; C-N; offspring exposed to a control diet before weaning and given naloxone injections; D1; dopamine receptor 1; D2; dopamine receptor 2; DAT; dopamine ac
Characterization by combined optical and FT infrared spectra of 3d-transition metal ions doped-bismuth silicate glasses and effects of gamma irradiation
Keywords: Bismuth silicate glass; Transition metal ions; Optical; FTIR spectroscopy; DAT; Gamma rays
Pharmacological profiles of aminoindanes, piperazines, and pipradrol derivatives
Keywords: Novel psychoactive substance; Monoamine; Transporter; Receptor; 2-AI; 2-aminoindane; BZP; 1-benzylpiperazine; DA; dopamine; DAT; dopamine transporter; D2PM; diphenyl-2-pyrrolidinemethanol; 2-DPMP; desoxypipradrol or 2-diphenylmethylpiperidine; HEK; human
Pharmacology of novel synthetic stimulants structurally related to the “bath salts” constituent 3,4-methylenedioxypyrovalerone (MDPV)
Keywords: 3,4-Methylenedioxypyrovalerone; α-PVP; Functional observational battery; Locomotor activity; Monoamine transporter; Synthetic cathinones; methylone; 3,4-methylenedioxymethcathinone; MDPV; 3,4-methylenedioxypyrovalerone; mephedrone; 4-methylmethcathinone;
The association of 5-HTR2A-1438A/G, COMTVal158Met, MAOA-LPR, DATVNTR and 5-HTTVNTR gene polymorphisms and borderline personality disorder in female heroin-dependent Chinese subjects
Keywords: ASPD; antisocial personality disorder; bp; base-pair; BPD; borderline personality disorder; COMT; catechol-O-methyltransferase gene; DA; dopamine; DAT; dopamine transporter gene; 5-HT; 5-hydroxytryptamine or serotonin; 5-HTR2A; 5-hydroxytryptamine recepto
Photosynthesis and fluorescence responses of Jatropha curcas to chilling and freezing stress during early vegetative stages
Keywords: DAT; Days after the end of the treatment; DAS; Days after sowing; Tc; Control treatment at outdoors everytime; Tb; Chamber control treatment subjected to continuous 15 ºC during 48 h; T4; Chilling treatment subjected to 4 ºC during 40 h; Tâ1; Free
Glutamate neurons within the midbrain dopamine regions
Keywords: DAT; dopamine transporter; EPSC; excitatory postsynaptic current; mPFC; medial prefrontal cortex; nAcc; nucleus accumbens; PBP; parabrachial pigmental nucleus; PN; paranigral nuclei; RRF; retrorubral field; SNC; substantia nigra pars compacta; TH; tyrosin
Aminorex, a metabolite of the cocaine adulterant levamisole, exerts amphetamine like actions at monoamine transporters
Keywords: SERT; serotonin transporter; NET; norepinephrine transporter; DAT; dopamine transporter; 5-HT; serotonin; DA; dopamine; KHB; Krebs-Ringer-HEPES buffer; HPLC; high performance liquid chromatography; LC-MS; liquid chromatography-mass spectrometry; L
RNA sequencing reveals high resolution expression change of major plant hormone pathway genes after young seedless grape berries treated with gibberellin
Keywords: ABA; abscisic acid; BR; brassinosteroid; DAT; days after treatment; GO; gene ontology; IAA; indoleacetic acid; qRT-PCR; quantitative real-time PCR; Additional berry enlargement; Gibberellin acid treatment; Plant hormone cross talk; Plant hormone gene expr
ReviewThe role of D2-autoreceptors in regulating dopamine neuron activity and transmission
Keywords: AC; adenylyl cyclase; D2-IPSCs; D2-autoreceptor-mediated inhibitory post-synaptic currents; DAT; dopamine transporter; GIRK; G-protein-activated inwardly rectifying potassium channels; GPCRs; G-protein-coupled receptors; LTD; long-term depression; VMAT; v
Subthalamotomy-induced changes in dopamine receptors in parkinsonian monkeys
Keywords: 6-OHDA; 6-hydroxydopamine; DA; dopamine; DAT; dopamine transporter; DL; dorsolateral; DM; dorsomedial; DOPAC; 3,4-dihydroxyphenylacetic acid; GPe; globus pallidus pars externa; GPi; globus pallidus pars interna; HFS; high-frequency stimulation; HPLC; high
Prolonged nicotine exposure down-regulates presynaptic NMDA receptors in dopaminergic terminals of the rat nucleus accumbens
Keywords: Nicotinic receptors; NMDA receptors; Calcium levels; Neurotransmitter release; Isolated nerve endings; Nucleus accumbens; ACh; acetylcholine; AMPA; α-Amino-3-hydroxy-5-methyl-4-isoxazolone propionate; DA; dopamine; DAT; dopamine transporter; ECL; enhance
An LED-based UV-B irradiation system for tiny organisms: System description and demonstration experiment to determine the hatchability of eggs from four Tetranychus spider mite species from Okinawa
Keywords: 6-4PP; pyrimidine (6-4) pyrimidone photoproduct; AT; air temperature; CPD; cyclobutane pyrimidine dimer; DAT; days after treatment; DR; duty ratio; λmax; peak wavelength; LD50; median lethal dose for 50% hatchability; LED; light-emitting diode; PC; perso
Effects of the Parkinsonian toxin MPP+ on electrophysiological properties of nigral dopaminergic neurons
Keywords: Dopamine; D2 autoreceptors; KATP channels; HCN channels; Brain slice; ACSF; artificial cerebrospinal fluid; ATP; adenosine triphosphate; DA; dopamine; DAT; dopamine transporter; GIRK; G protein-coupled inwardly rectifying potassium channels; HCN; hyperpol
Research reportPramipexole but not imipramine or fluoxetine reverses the “depressive-like” behaviour in a rat model of preclinical stages of Parkinson's disease
Keywords: Depression; Chronic pramipexole; Parkinson's disease; Preclinical stages; Rat model; 3-MT; 3-methoxytyramine; 5-HIAA; 5-hydroxyindoleacetic acid; 6-OHDA; 6-hydroxydopamine; CP; caudate-putamen; DAT; dopamine transporter; DOPAC; 3,4-dihydroxyphenylacetic a
Lack of BDNF expression through promoter IV disturbs expression of monoamine genes in the frontal cortex and hippocampus
Keywords: AdR; adrenergic receptor; BDNF; Brain-derived neurotrophic factor; Ct; cycle threshold; DAT; dopamine transporter; DRD2; dopamine D2 receptor; DRD4; dopamine D4 receptor; EDTA; ethylenediaminetetraacetic acid; EPSC; excitatory postsynaptic current; FC; fr
Defining the blanks - Pharmacochaperoning of SLC6 transporters and ABC transporters
Keywords: ABC transporters; ATP-binding cassette containing transporters; DAT; dopamine transporter; ER; endoplasmic reticulum; GAT; GABA transporter with 4 isoforms (GAT-1, GAT-2, GAT-3, GAT-4); NBD; nucleotide binding domains; NET; norepinephrine transporter; SLC
Increased dopaminergic innervation in the brain of conditional mutant mice overexpressing Otx2: Effects on locomotor behavior and seizure susceptibility
Keywords: 5-HT; serotonin; ANOVA; analysis of variance; DA; dopamine; Dat; dopamine transporter; EEG; electroencephalographic recordings; GAD65; glutamic acid decarboxylase 65Â kD; GCL; granule cell layer of the dentate gyrus; glyco-Dat; glycosylated active form of
A multivariate approach linking reported side effects of clinical antidepressant and antipsychotic trials to in vitro binding affinities
Keywords: 5-HT; 5-hydroxy tryptamine (serotonin); 5-HTT; serotonin transporter; AAP; atypical antipsychotics; ACH; acetylcholine; ADR; adverse drug reaction; AP; antipsychotic; CDSR; cochrane database of systematic reviews; CTZ; chemotrigger zone; DAT; dopamine tra
Increased DAT binding in the early stage of the dopaminergic lesion: A longitudinal [11C]PE2I binding study in the MPTP-monkey
Keywords: [11C]PE2I; (E)-N-(3-iodoprop-2-enyl)-2beta-carbomethoxy-3beta-(4â²-methylphenyl)-nortropane labeled with carbon 11; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP); PET; Positron Emission Tomography; NHP; non-human primate; DAT; Dopamine innerv
Salvinorin A regulates dopamine transporter function via a kappa opioid receptor and ERK1/2-dependent mechanism
Keywords: Kappa opioid receptor; Dysphoric; Pro-depressant; Dopamine transporter; Serotonin transporter; Trafficking; Salvinorin A; ASP+; trans 4-(4-(dimethylamino)-styryl)-N-methylpyridinium); BNI; nor-binaltorphimine; BRET; Biolumiescence resonance energy transfe
Flexible and biomimetic analogs of triple uptake inhibitor 4-((((3S,6S)-6-benzhydryltetrahydro-2H-pyran-3-yl)amino)methyl)phenol: Synthesis, biological characterization, and development of a pharmacophore model
Keywords: SSRI; selective serotonin reuptake inhibitors; SNRI; serotonin/norepinephrine reuptake inhibitors; MAO; monoamine oxidase inhibitors; TCA; tricyclic antidepressants; DAT; dopamine transporter; SERT; serotonin transporter; NET; norepinephrine transporters;
ReviewSex-dependent diversity in ventral tegmental dopaminergic neurons and developmental programing: A molecular, cellular and behavioral analysis
Keywords: AGT; antenatal glucocorticoid treatment; AR; androgen receptor; DA; dopamine; DAT; DA transporter; DHT; dihydrotestosterone; ER; estrogen receptor; HPA; hypothalamo-pituitary-adrenal; IR; immunoreactivity; mPFC; medial prefrontal cortex; NAc; nucleus
Drosophila melanogaster as a genetic model system to study neurotransmitter transporters
Keywords: 5HT; 5-hydroxytryptamine (serotonin); ACh; acetylcholine; ASD; autism spectrum disorder; ChT; choline transporter; ChAT; choline acetyl transferase; DA; dopamine; Ddc; dopa decarboxylase; EAAT; excitatory amino acid transporter; GABA; gamma amino butyric
Update on the pharmacology of selective inhibitors of MAO-A and MAO-B: Focus on modulation of CNS monoamine neurotransmitter release
Keywords: Enzyme active site structure; Presynaptic inhibition; Exocytotic and non-exocytotic release; Neuroprotection; Parkinson's disease; Affective disorders; MAO; monoamine oxidase; MAO-A; monoamine oxidase isoform A; MAO-B; monoamine oxidase isoform B; COMT; c
ReviewAn update on the connections of the ventral mesencephalic dopaminergic complex
Keywords: Acb; accumbens; BST; bed nucleus of the stria terminalis; c; caudal; CCK; cholecystokinin; CeA; central amygdaloid nucleus; CPu; caudate-putamen; DA; dopamine and dopaminergic; DAT; dopamine transporter; dc; dorsal, caudal; dl; dorsolateral; EA; extended
α-Synuclein and mitochondrial bioenergetics regulate tetrahydrobiopterin levels in a human dopaminergic model of Parkinson disease
Keywords: PD; Parkinson disease; SNPc; substantia nigra pars compacta; α-syn; α-synuclein; GTPCH; GTP cyclohydrolase I; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; MPP+; 1-methyl-4-phenylpyridinium; NOS; nitric oxide synthase; DAT; dopamine transporter; B
Realis mood, focus, and existential closure in Tundra Yukaghir
Keywords: ACC; accusative; AF; transitive subject focus; ATTR; attributive; AUG; augmentative; CJT; conjectural; COM; comitative; COND; conditional; DAT; dative; DES; desiderative; DS; different subject; EV; evidential; EX; existential; NP/FCI; negative polarity/fr
Modifications of laccase activities of copper efflux oxidase, CueO by synergistic mutations in the first and second coordination spheres of the type I copper center
Keywords: MCO; multicopper oxidase; T1; type I; TNC; trinuclear center; T2; type II; T3; type III; ABTS; 2,2â²-azinobis(3-ethylbenzothiazoline-6-sulfonic acid); BCA; bicinnchoninic acid; DAT; 2,5-diaminotoluene; DMP; 2,6-dimethoxyphenol; p-PD; p-phenylenediamine;
Pleiotrophin is involved in the amniotic epithelial cell-induced differentiation of human umbilical cord blood-derived mesenchymal stem cells into dopaminergic neuron-like cells
Keywords: hUCB-MSCs; human umbilical cord blood-derived mesenchymal stem cells; DA neuron; dopaminergic neuron; AECs; amniotic epithelial cells; ACM; AEC-conditioned medium; PTN; pleiotrophin; NSE; neuron-specific enolase; DAT; dopamine transporter; TH; tyrosine hy
Lsamp-/- mice display lower sensitivity to amphetamine and have elevated 5-HT turnover
Keywords: 3-MT; 3-methoxytyramine; 5-HIAA; 5-hydroxyindoleacetic acid; 5-HT; serotonin; DA; dopamine; DAT; dopamine transporter; DOPAC; 3,4-dihydroxyphenylacetic acid; HVA; homovanillic acid; LAMP; limbic system-associated membrane protein; Lsamp; limbic-system-ass
Parkinson's disease cognitive network correlates with caudate dopamine
Keywords: PD; Parkinson's disease; PDCP; Parkinson's disease cognition-related pattern; PDRP; Parkinson's disease motor-related pattern; DAT; dopamine transporter; FDG; [18F]-fluorodeoxyglucose; FPCIT; [18F]-fluoropropyl-β-CIT; UPDRS; Unified Parkinson's Disease R
Predischarge Screening for Severe Neonatal Hyperbilirubinemia Identifies Infants Who Need Phototherapy
Keywords: AAP; American Academy of Pediatrics; AUC; Area under the curve; CAP; College of American Pathologists; DAT; Direct antiglobulin test (Coombs); G6PD; Glucose-6-phosphate dehydrogenase; GA; Gestational age; TSB; Total plasma/serum bilirubin; TcB; Transcutan
Down-regulation of LRRK2 in control and DAT transfected HEK cells increases manganese-induced oxidative stress and cell toxicity
Keywords: LRRK2; leucine-rich repeat kinase 2; DAT; dopamine transporter; DA; dopamine; Mn; manganese; HEK; human embryonic kidney; ROS; reactive oxygen species; JNK; c-Jun N-terminal kinases; p38; 38 mitogen-activated protein kinase; AP13A2; probable cation-transp
The atypical dopamine transport inhibitor, JHW 007, prevents amphetamine-induced sensitization and synaptic reorganization within the nucleus accumbens
Keywords: AMPH; Amphetamine; BZT; Benztropine; DAT; Dopamne transporter; MSNs; Medium spiny neurons; FADD; Fas-associated death domain; JHW 007; [(N-(n-butyl)-3α-[bis(4â²-fluorophenyl)methoxy]-tropane)]; AHN 1055; [3α-[bis(4'-fluorophenyl)methoxy]-tropane]; NAc;
Rostrocaudal gradients of dopamine D2/3 receptor binding in striatal subregions measured with [11C]raclopride and high-resolution positron emission tomography
Keywords: AC; anterior commissure; AP; anterior-posterior; BPND; non-displaceable binding potential; DA; dopamine; DAT; dopamine transporter; DCA; dorsal caudate nucleus; DPU; dorsal putamen; HRRT; high-resolution research tomography; MSA; multiple system atrophy
Research ReportRNA interference targeting α-synuclein attenuates methamphetamine-induced neurotoxicity in SH-SY5Y cells
Keywords: METH; methamphetamine; α-syn; α-synuclein; LBs; Lewy bodies; DA; dopamine; TH; tyrosine hydroxylase; DAT; dopamine transporter; VMAT-2; vesicular monoamine transporter 2; ROS; reactive oxygen species; NOS; nitric oxide synthase; NO; nitrogen monoxide; Î
Synthetic retinoid Am80 results in improved exploratory and emotional behavior in the P8 substrain of senescence-accelerated mice
Keywords: SAM; senescence-accelerated mouse; SAMP8; P8 strain of senescence-accelerated mice; SAMP; senescence-accelerated prone mouse; SAMR; senescence-accelerated resistant mouse; ATRA; all-trans retinoic acid; RAR; retinoic acid receptor; RXR; retinoid X recepto
Combination of prenatal immune challenge and restraint stress affects prepulse inhibition and dopaminergic/GABAergic markers
Keywords: CNS; central nervous system; D2R; dopamine D2 receptor; DAT; dopamine transporter; GAD67; the 67 kDa form of glutamic acid decarboxylase; IL-1β; interleukin-1β; IL-6; interleukin-6; NMDA; N-methyl D-aspartate; PIC; Poly I:C (poly-inosinic/cytidylic acid
Regional variation in IIM myosin heavy chain expression in the temporalis muscle of female and male baboons (Papio anubis)
Keywords: DAT; deep anterior temporalis; MyHC; myosin heavy chain; SAT; superficial anterior temporalis; SPT; superficial posterior temporalis; Myosin type composition; Mastication; Muscle; Anatomy;
Rit subfamily small GTPases: Regulators in neuronal differentiation and survival
Keywords: CA; constitutively active; cAMP; cyclic adenosine monophosphate; CaM; calmodulin; CCI; controlled cortical impact; CREB; cAMP response element binding protein; CRIB; Cdc42/Rac interactive binding; DA; dopamine; DAT; dopamine transporter; DN; dominant nega
Neurobehavioral alterations in HIV-1 transgenic rats: Evidence for dopaminergic dysfunction
Keywords: ANOVA; Analysis of variance; ASR; Auditory startle response; BAEP; Brain auditory evoked potentials; CART; Combination antiretroviral therapy; DA; Dopamine; DAT; Dopamine transporter; HIV-1; Human immunodeficiency virus-1; HAND; HIV-1 associated neurologi
Exploring the interacting effect of soil texture and bulk density on root system development in tomato (Solanum lycopersicum L.)
Keywords: 3D; three-dimensional; μCT; micro-Computed Tomography; RSA; root system architecture; DAT; days after transplanting; Solanum lycopersicum; Root system architecture; Soil compaction; Soil texture; X-ray micro-Computed Tomography (μCT); Root washing;
Research reportAuditory event-related potentials (P3a, P3b) and genetic variants within the dopamine and serotonin system in healthy females
Keywords: ERP; event-related potential; EEG; electroencephalogram; DA; dopamine; DAT; dopamine transporter; COMT; catechol-O-methyltransferase; 5HT; serotonin; 5HTT; serotonin transporter; 5HTTLPR; serotonin transporter long polymorphic region; VNTR; variable numbe
Lack of CCR5 modifies glial phenotypes and population of the nigral dopaminergic neurons, but not MPTP-induced dopaminergic neurodegeneration
Keywords: PD; Parkinson's disease; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; MPPÂ +; 1-methyl-4-phenyl pyridium; MAO; monoamine oxidase; DAT; dopamine transporter; CCR; C-C chemokine receptor; MIP; macrophage inflammatory protein; KO; knockout; WT; wild