Keywords: Rosa chinensis; Flower fragrance; Monoterpene biosynthesis pathways; Terpene synthases; (â)-(3R)-linalool; (+)-(3S)-linalool; Nerolidol; DMAPP; dimethylallyl diphosphate; EST; expressed sequence tag; FPP; farnesyl pyrophosphate; GFP; green fluorescent p
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Keywords: Terpene fold; Trichodiene synthase; Catalytic site evolution; Single domain proteins; Multi-domain proteins; EAS; 5-epi-aristolochene synthase; PS; Pentalenene synthase; EIZS; Epi-isozizaene synthase; CS; 1,8-cineole synthase; DMAPP; Dimethylallyl diphosp
Keywords: CCD; carotenoid cleavage dioxygenase; CHYB; β-carotene hydroxylase; DAFB; days after full bloom; DMAPP; dimethylallyl diphosphate; FPP; farnesyl diphosphate; FPPS; farnesyl diphosphate synthase; FW; fresh weight; GGPP; geranylgeranyl diphosphate; GGPS; g
Relationship between isoprene emission and photosynthesis in diatoms, and its implications for global marine isoprene estimates
Keywords: a*; Chlorophyll optical absorption cross-section; ATP; Adenosine triphosphate; Chl; Chlorophyll; DMAPP; Dimethylalyl pyrophosphate; ETR; Electron transport rate; Fm; Maximum chlorophyll fluorescence yields in dark adapted state; Fmâ²; Maximum chlorophyll
Keywords: AaADS; Artemisia annua amorpha-4,11-diene synthase; AaFS; Artemisia annua β-farnesene synthase; CAT; chloramphenicol acetyltransferase; DMAPP; dimethylallyl diphosphate; DXP; deoxyxylulose-5-phosphate; FCM; fluorescence-activated cell sorting by flow cyt
Keywords: Isoprenoids; Metabolic engineering; Protein engineering; Combinatorial biosynthesis; Cytochrome P450; TPS; terpene synthase; GPP; geranyl diphosphate; DMAPP; dimethylallyl diphosphate; IPP; isopentenyl diphosphate; FPP; farnesyl diphosphate; GGPP; geranyl
Keywords: %; Percentage; °C; degree celsius; ABE; acetone-butanol-ethanol; ASTM; American Society for Testing and Materials; atm; standard atmosphere (unit); ATP; adenosine triphosphate; AXE; acetyl xylan esterase; C; carbon; CBM; carbohydrate binding modules;
Keywords: IspS; isoprene synthase; DMAPP; dimethylallyl pyrophosphate; MEP; methylerythritol phosphate; MEV; mevalonate; IPTG; isopropyl β-D-1-thiogalactopyranoside; CDW; cell dry weight; TSP; terpene synthase; TSP-b; terpene synthase protein family clade b; MSA;
Keywords: CAS; cycloartenol synthase; DDS; dammarenediol synthase; DMAPP; dimethylallyl diphosphate; DXP; 1-deoxy-d-xylulose 5-phosphate; FPP; farnesyl pyrophosphate; FPS; farnesyldiphosphate synthase; GAP; glyceraldehyde 3-phosphate; HMGR; 3-hydroxy-3-methylglutar
Keywords: MEP; methylerythritol phosphate; MVA; mevalonate; DXS; deoxyxylulose-5-phosphate synthase; HMGR; hydroxymethylglutaryl coenzyme A reductase; DOX; 1-deoxy-d-xylulose; IPP; isopentenyl diphosphate; DMAPP; dimethylallyl diphosphate; Gossypium hirsutum L. (co
Keywords: ABC; ATP-binding cassette; ADH; alcohol dehydrogenase; ADR; adrenodoxin reductase; ADX; adrenodoxin; ARE2; sterol acyltransferase; ARV1; mediator of sterol homeostasis; BTS1; GGPP synthase; CPR; cytochrome P450 reductase; CRT; carotenogenic (genes); CYP;
Keywords: AACT; acetoacetyl-CoA thiolase; ADP; adenosine diphosphate; APC; allophycocyanin; ATP; adenosine triphosphate; BChl; bacteriochlorophyll; CAR; carotenoid; CDP-ME2P; 4-(citidine 5â²-diphospho)-2-C-methyl-d-erythritol; Chl; chlorophyll; CHYβ; β-hydroxyla
Biosynthetic machinery for C25,C25-diether archaeal lipids from the hyperthermophilic archaeon Aeropyrum pernix
Keywords: Archaea; Archaeal lipid; Hyperthermophile; Isoprenoid; Phospholipid; Prenyltransferase; DGFGP; digeranylfarnesylglyceryl phosphate; DGGGP; digeranylgeranylglyceryl phosphate; DGFGP-glycerol; digeranylfarnesylglyceryl phosphoglycerol; DMAPP; dimethylallyl
In-situ isopentenol production from Bacillus subtilis through genetic and culture condition modulation
Keywords: CSIR; Council for Scientific and Industrial Research; DMAPP; Dimethylallyl pyrophosphate; DXP; 1-deoxy-d-xylulose-5-phosphate; dxs; 1-deoxy-d-xylulose-5-phosphate synthase; G3P; Glyceraldehyle-3-phosphate; GC-FID; Gas Chromatography-Flame Ionization Det
Engineering metabolic pathways in Amycolatopsis japonicum for the optimization of the precursor supply for heterologous brasilicardin congeners production
Keywords: Norcardia terpenica IFM0406; Mevalonate pathway; Isoprenoids; Prenyltransferases; Aact; acetoacetyl CoA thiolase; BraA; brasilicardin A; BraB; brasilicardin B; BraC; brasilicardin C; BraD; brasilicardin D; BraC-agl; brasilicardin C aglycon; BraD-agl; bras
Effect of exogenous auxin on aroma volatiles of cherry tomato (Solanum lycopersicum L.) fruit during postharvest ripening
Keywords: AADC; aromatic amino acid decarboxylase; ADH; alcohol dehydrogenase; BCAT; branched-chain aminotransferases; CCD; carotenoid cleavage dioxygenases; DAHP; 3-deoxy-d-arabino-heptulosonate 7-phosphate; DMAPP; dimethylallyl diphosphate; F-6-P; fructose-6-phos
Diverse responses of tanshinone biosynthesis to biotic and abiotic elicitors in hairy root cultures of Salvia miltiorrhiza and Salvia castanea Diels f. tomentosa
Keywords: AACT; acetyl-CoA C-acetyltransferase; CPS; copalyl diphosphate synthase; CT; cryptotanshinone; CYPs; cytochromes P450; DMAPP; dimethylallyl diphosphate; DT-I; dihydrotanshinone I; DXR; 1-deoxy-d-xylulose 5-phosphate reductoisomerase; DXS; 1-deoxy-d-xylulo
Phototrophic production of heterologous diterpenoids and a hydroxy-functionalized derivative from Chlamydomonas reinhardtii
Keywords: cdm; cell dry mass; IPP; isopentenyl pyrophosphate; DMAPP; dimethylallyl pyrophosphate; FPPs; farnesyl pyrophosphate (synthase); GGPP; geranylgeranyl pyrophosphate; TAP; Tris acetate phosphate medium; YFP; mVenus yellow fluorescent protein; CFP; mCerulean
Tailored carbon partitioning for phototrophic production of (E)-α-bisabolene from the green microalga Chlamydomonas reinhardtii
Keywords: AgBs; Abies grandis bisabolene synthase; amiRNA; artificial micro ribonucleic acid; CDW; cell dry weight;; IPP; isopentenyl pyrophosphate; DMAPP; dimethylallyl pyrophosphate; FPP; farnesyl pyrophosphate; GGPP; geranylgeranyl pyrophosphate; TAP; Tris Aceta
The human tRNA-modifying protein, TRIT1, forms amyloid fibers in vitro
Keywords: tRNA; transfer ribonucleic acid; TRIT1; tRNA isopentenyl transferase; DMAPP; dimethylallyl pyrophosphate; tgm silencing; tRNA gene mediate silencing; IPTase; tRNA isopentenyl transferase; ThT; thioflavin T; CR; Congo red; pol II; RNA polymerase II; pol II
Regular articleGenetic manipulation of the bifunctional gene, carRA, to enhance lycopene content in Blakeslea trispora
Keywords: CarA; phytoene synthase; CarB; phytoene dehydrogenase; carG; geranylgeranyl pyrophosphate synthase gene; CarR; lycopene cyclase; coq2; 4-hydroxybenzoate polyprenyl transferase gene; CTAB; cetyl trimethyl ammonium bromide; DMAPP; dimethylallyl pyrophosphat
Floral scent: Regulation and role of MYB transcription factors
Keywords: ACP; acyl-acyl carrier protein; AOS; allege oxide synthase; DMAPP; dimethyl allyl diphosphate; FPP; farnesyl pyrophosphate; FPPS; farnesyl pyrophosphate synthase; GPP; geranyl diphosphate; GGPP; geranylgeranyl diphosphate farnesyl diphosphate; IPP; isop
OsMYC2 mediates numerous defence-related transcriptional changes via jasmonic acid signalling in rice
Keywords: Defense response; Jasmonic acid signaling; OsMYC2; Rice; RNA-sequencing; Specialized metabolite; JA; Jasmonic acid; bHLH; basic helix-loop-helix; TFs; transcription factors; JA-Ile; jasmonoyl-L-isoleucine; JAZ; jasmonate-ZIM domain protein; RNA-Seq; RNA-s
Knowns and unknowns of membrane lipid synthesis in streptomycetes
Keywords: Streptomyces; Phospholipids; Phosphatidylinositol; PIMs; Hopanoids; Ornithine lipid; G3P; glycerol-3-phosphate; LPA; lyso-phosphatidic acid; PA; phosphatidic acid; CDP-DAG; cytidine diphosphate diacylglycerol; PE; phosphatidylethanolamine; PS; phosphatidy
Cytokinin biosynthesis ISOPENTENYLTRANSFERASE genes are differentially expressed during phyllomorph development in the acaulescent Streptocarpus rexii (Gesneriaceae)
Keywords: BAP; 6-Benzylaminopurine; cZ; cis-Zeatin; cZR; cZ riboside; cZRPs; cZR 5â²-phosphates; DAU; days after cotyledon unfolding; DIG; digoxygenin; DMAPP; dimethylallyl diphosphate; DMSO; dimethylsulfoxide; DZ; dihydrozeatin; DZR; DZ riboside; DZRPs; DZR 5â²-
Two Eucommia farnesyl diphosphate synthases exhibit distinct enzymatic properties leading to end product preferences
Keywords: Eucommia; Farnesyl diphosphate synthase; Metal ion dependency; Prenyltransferase; Substrate inhibition; CLD; chain length determination; DMAPP; dimethylallyl diphosphate; DOPE; discrete optimized protein energy; FPP; farnesyl diphosphate; FPS; farnesyl di
Biosynthesis of β-caryophyllene, a novel terpene-based high-density biofuel precursor, using engineered Escherichia coli
Keywords: β-Caryophyllene; DXP pathway; MVA pathway; Escherichia coli; DMAPP; dimethylallyl pyrophosphate; IPP; isopentenyl pyrophosphate; GPP; geranyl diphosphate; MVA; mevalonate; DXP; 1-Deoxy-d-Xylulose 5-Phosphate; IPTG; isopropyl β-D-thiogalactoside; PCR; po
CRISPR interference-guided balancing of a biosynthetic mevalonate pathway increases terpenoid production
Keywords: CRISPR; Clustered regularly interspaced short palindromic repeats; CRISPRi; Clustered regularly interspaced short palindromic repeats interference; MVA; mevalonate; sgRNA; single guide RNA; dCas9; inactive Cas9; IPP; isopentenyl diphosphate; DMAPP; dimeth
Isoprenoid generating systems in plants - A handy toolbox how to assess contribution of the mevalonate and methylerythritol phosphate pathways to the biosynthetic process
Keywords: Ac-CoA; acetyl CoA; AACT; AcAC-CoA thiolase; CLM; clomazone (2-[(2-chlorophenyl)methyl]-4,4-dimethyl-3-isoxazolidinone); DMAPP; dimethylallyl diphosphate; DMNT; (3E)-4,8-dimethyl-1,3,7-nonatriene; DOXP; deoxyxylulose phosphate; DX; 1-deoxy-d-xylulose; DXK
Rhizosphere associated bacteria trigger accumulation of terpenes in leaves of Vitis vinifera L. cv. Malbec that protect cells against reactive oxygen species
Keywords: Vitis vinifera L.; Microbacterium imperiale; Kocuria erythromyxa; Terribacillus saccharophilus; Terpenes; Oxygen consumption; Antioxidant compounds; + K. erythromyxa; bacterized with Kocuria erythromyxa; + M. imperiale; bacterized with Microbacterium im
Synthetic ceramide analogues increase amyloid-β 42 production by modulating γ-secretase activity
Keywords: AD; Alzheimer disease; FAD; familial AD; Aβ; amyloid-β peptide; APP; amyloid precursor protein; BACE1; β-site APP cleaving enzyme 1; PDMP; dl-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol; DMAPP; (1S,2R-d-erythro-2-N-myristoylamino)-1-phenyl-1
De novo characterization of the Lycium chinense Mill. leaf transcriptome and analysis of candidate genes involved in carotenoid biosynthesis
Keywords: CHYB; β-carotene hydroxylase; COG; Cluster of Orthologous Group; CRTISO; carotene isomerase; DMAPP; dimethylallyl pyrophosphate; Gbp; gigabase pairs; GGPP; geranylgeranyl pyrophosphate; GGPS; geranylgeranyl diphosphate synthase; GO; Gene Ontology; IPP; i
The inhibition of human farnesyl pyrophosphate synthase by nitrogen-containing bisphosphonates. Elucidating the role of active site threonine 201 and tyrosine 204 residues using enzyme mutants
Keywords: DMAPP; dimethylallyl pyrophosphate; FPP; farnesyl pyrophosphate; FPPS; farnesyl pyrophosphate synthase; GPP; geranyl pyrophosphate; IPP; isopentenyl pyrophosphate; N-BP; nitrogen-containing bisphosphonates; TCEP; tris(2-carboxyethyl)phosphine; RIS; Risedr
Production of dammarane-type sapogenins in rice by expressing the dammarenediol-II synthase gene from Panax ginseng C.A. Mey
Keywords: DS; Dammarenediol-II synthase; T-DNA; Transfer-DNA; HPLC; High performance liquid chromatography; PPD; 20 (S)-Protopanaxadiol; PPT; 20 (S)-Protopanaxatriol; DAD; Dammarenediol-II; ESI; Electrospray ionization; EIC; Extracted ion chromatogram; PSY; Phyto
Efficient diterpene production in yeast by engineering Erg20p into a geranylgeranyl diphosphate synthase
Keywords: geranyl diphosphate; GPP; dimethylallyl diphosphate; DMAPP; isopentenyl diphosphate; IPP; farnesyl diphosphate; FPP; geranylgeranyl diphosphate; GGPP; nerolidol; NOH; farnesol; FOH; geraniol; GOH; linalool; LOH; geranylgeraniol; GGOH; geranyllinalool; GLO
Human Vγ9/Vδ2 T cells: Innate adaptors of the immune system
Keywords: APC; antigen presenting cell; BCG; bacillus Calmette-Guérin; BTN3A; butyrophilin 3A (CD277); DC; dendritic cell; DMAPP; dimethylallyl pyrophosphate; α-GC; α-galactosylceramide; HMB-PP; (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate; ICOS; inducible
Disruption of the mevalonate pathway induces dNTP depletion and DNA damage
Keywords: ACN; acetonitrile; BrdU; 5-bromo-2â²-deoxyuridine; DMAPP; dimethylallyl diphosphate; dNs; deoxyribonucleosides; dNTP; deoxyribonucleoside triphosphate; E2F; E2 transcription factor; Fmev; 6-fluoromevalonate; IPP; isopentenyl diphosphate; HU; hydroxyurea;
The low temperature induced rate of 3-hydroxy-3-methylglutaryl-CoA reductase in Parthenium argentatum Gray limits the theoretical rate of rubber formation
Keywords: Partheniumar gentatum Gray; Chihuahuan Desert; 3-Hydroxy-3-methylglutaryl-CoA reductase; Rubber transferase; Rubber induction; Quantitative rubber biosynthesis; HMGS; 3-hydroxy-3-methylglutaryl-CoA synthase; HMGR; 3-hydroxy-3-methylglutaryl-CoA reductase;
Profiling of defense responses in Escherichia coli treated with fosmidomycin
Keywords: 1-Deoxy-d-xylulose 5-phosphate reducto-isomerase; Fosmidomycin; Isoprenoid; Antibiotics; Resistance acquisition; 2-D DIGE; 2-D fluorescence difference gel electrophoresis; DMAPP; dimethylallyl diphosphate; FosR; fosmidomycin resistant strain; FosS; fosmid
Substrate specificity of undecaprenyl diphosphate synthase from the hyperthermophilic archaeon Aeropyrum pernix
Keywords: DMAPP; dimethylallyl diphosphate; FPP; farnesyl diphosphate; GGPP; geranylgeranyl diphosphate; GFPP; geranylfarnesyl diphosphate; GPP; geranyl diphosphate; HexPP; hexaprenyl diphosphate; IPP; isopentenyl diphosphate; UPP; undecaprenyl diphosphate; Isopren
Uniconazole, a cytochrome P450 inhibitor, inhibits trans-zeatin biosynthesis in Arabidopsis
Keywords: ABA; abscisic acid; BA; 6-benzylaminopurine; BR; brassinosteroid; βGlc; β-glucosidase; CK; cytokinin; CKXs; cytokinin oxidase/dehydrogenases; cZ; cis-zeatin; cZR; cis-zeatin riboside; cZRMP; cis-zeatin riboside 5â²-monophosphate; cZRPs; cis-zeatin ribo
Methylerythritol phosphate pathway to isoprenoids: Kinetic modeling and in silico enzyme inhibitions in Plasmodium falciparum
Keywords: BLAST; basic local alignment search tool; BLAST-P; protein BLAST; CCC; concentration control coefficient; CDPME; 4-(cytidine 5â²-diphospho)-2-C-methyl-d-erythritol; CDPMEK; 4-(cytidine 5â²-diphospho)-2-C-methyl-d-erythritol kinase; CDPMES; 4-(cytidine 5
Cloning, molecular characterization and functional analysis of 1-hydroxy-2-methyl-2-(E)-butenyl-4-diphosphate reductase (HDR) gene for diterpenoid tanshinone biosynthesis in Salvia miltiorrhiza Bge. f. alba
Keywords: Salvia miltiorrhiza Bge. f. alba; SmHDR1; Expression profiling; Tanshinones; Hairy root; CTAB; cetyltrimethylammonium bromide; DMAPP; dimethylallyl diphosphate; DXR; 1-deoxy-d-xylulose 5-phosphate reductoisomerase; DXS; 1-deoxy-d-xylulose 5-phosphate synt
ReviewEngineered Escherichia coli as new source of flavonoids and terpenoids
Keywords: GI; gastrointestinal; Top1; eukaryotic topoisomerase; AMPK; AMP-activated protein kinase; NF; nuclear factor; LDL; low-density-lipoprotein; IL; interleukin; PPAR; peroxisome proliferator-activated receptor; IPP; isopentenyl diphosphate; DMAPP; isomer dime
Functional and evolutionary analysis of DXL1, a non-essential gene encoding a 1-deoxy-D-xylulose 5-phosphate synthase like protein in Arabidopsis thaliana
Keywords: aLRT; approximate likelihood ratio tests; Ap; ampicillin; BEB; Bayes Empirical Bayes; cDNA; DNA complementary to RNA; Cm; chloramphenicol; DMAPP; dimethylallyl diphosphate; DXS; 1-deoxy-D-xylulose 5-phosphate synthase; DX5P; 1-deoxy-D-xylulose 5-phosphate
De novo sequencing and assembly of Centella asiatica leaf transcriptome for mapping of structural, functional and regulatory genes with special reference to secondary metabolism
Keywords: APX; Ascorbate peroxidase; BAS; Beta amyrin synthase; BDA; BLAST description annotator; BLAST; Basic local alignment search Tool; B2G; BLAST2GO; CAS; Cycloartenol synthase; CAT; Catalase; DIP; Deletion insertion polymorphism; DMAPP; Dimethyl allyl pyropho
Post-translational events and modifications regulating plant enzymes involved in isoprenoid precursor biosynthesis
Keywords: DMAPP; dimethylallyl diphosphate; FPP; farnesyl diphosphate; GGPP; geranylgeranyl diphosphate; GPP; geranyl diphosphate; HMG-CoA; 3-hydroxy-3-methylglutaryl-coenzyme A; LC; liquid chromatography; ROS; reactive oxygen species; Isoprenoid biosynthesis; Meth
The single cellular green microalga Botryococcus braunii, race B possesses three distinct 1-deoxy-d-xylulose 5-phosphate synthases
Keywords: MEP; methylerythritol 4-phosphate; DXS; 1-deoxy-d-xylulose 5-phosphate synthase; IPP; isopentenyl diphosphate; DMAPP; dimethylally diphosphate; MVA; mevalonate; DXP; 1-deoxy-d-xylulose 5-phosphate; NTR; non-translated region; TLC; thin-layer chromatograph
A raison d'être for two distinct pathways in the early steps of plant isoprenoid biosynthesis?
Keywords: AACT; acetoacetyl-coenzyme A thiolase; Ac-CoA; acetyl-coenzyme A; AcAc-CoA; acetoacetyl-coenzyme A; ADP; adenosine diphosphate; ATP; adenosine triphosphate; CDP-ME; 4-diphosphocytidyl-2C-methyl-d-erythritol; CDP-MEP; 4-diphosphocytidyl-2C-methyl-d-erythri
Correlation between time-dependent inhibition of human farnesyl pyrophosphate synthase and blockade of mevalonate pathway by nitrogen-containing bisphosphonates in cultured cells
Keywords: ApppI; triphosphoric acid 1-adenosin-5â²-yl ester 3-(3-methylbut-3-enyl) ester; DMAPP; dimethylallyl pyrophosphate; ESI; electrospray ionization; FPPS; farnesyl pyrophosphate synthase; IPP; isopentenyl pyrophosphate; HPLC; high-performance liquid chromat