دانلود مقالات ISI درباره Dmem + ترجمه فارسی

Deactivation of the NLRP3 inflammasome in infiltrating macrophages by duodenal-jejunal bypass surgery mediates improvement of beta cell function in type 2 diabetes

Keywords: ASC; apoptosis-associated speck-like protein; AUC; area under the curve; CRP; circulating C-reactive protein; CD68; Cluster of Differentiation 68; DIO; diet-induced obesity; DMEM; Dulbecco's Modified Eagle Medium; DJB; duodenal-jejunal bypass; FBS; fetal

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Neural progenitors derived from Tuberous Sclerosis Complex patients exhibit attenuated PI3K/AKT signaling and delayed neuronal differentiation

Keywords: TSC; Tuberous Sclerosis Complex; mTOR; mammalian target of rapamycin; mTORC1; mTOR complex 1; LOH; loss of heterozygosity; iPSCs; induced pluripotent stem cells; NPCs; neural progenitor cells; PI3K; phosphoinositide 3-kinase; SENs; subependymal nodules; S

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Oroxin A from Oroxylum indicum prevents the progression from prediabetes to diabetes in streptozotocin and high-fat diet induced mice

Keywords: Oroxin A; Prediabetes; Type 2 diabetes; PPARγ; Mechanism; 2h-PG; 2-h postprandial glucose; ALT; alanine transaminase; AST; aspartate transaminase; AUC; area under the curve; CMC-Na; Sodium carboxymethylcellulose; CαRMSD; Cα root mean square deviation;

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

A constitutively-active IKK-complex at the axon initial segment

Keywords: Axon initial segment; NF-κB; IKK 2 Kinase; Ankyrin-G; Proximity ligation assay; Axon; AIS; axon initial segment; ASA; acetyl-salicylic acid; DMEM; Dulbecco's modified Eagle media; eGFP; enhanced green-fluorescent protein; FADD; Fas-associated death dom

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

miR-1275 controls granulosa cell apoptosis and estradiol synthesis by impairing LRH-1/CYP19A1 axis

Keywords: ChIP; chromatin immunoprecipitation; CL; corpus luteal cell; CV; coefficient of variation; DMEM; Dulbecco's Modified Eagle's Medium; FBS; fetal bovine serum; FSH; follicle-stimulating hormone; GC; granulosa cell; H; healthy; EA; early atresia; PA; progres

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Diacylglycerol acyltransferase-2 contains a c-terminal sequence that interacts with lipid droplets

Keywords: AGPAT3; 1-acylglycerol-3-phosphate acyltransferase-3; CCTα; CTP:phosphocholine cytidylyltransferase α; CoA; coenzyme A; DG; 1,2-diacylglycerol; DGAT; acyl CoA:diacylglycerol acyltransferase; DMEM; Dulbecco's modified Eagle's medium; ER; endoplasmic reti

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

CNOT2 promotes proliferation and angiogenesis via VEGF signaling in MDA-MB-231 breast cancer cells

Keywords: CNOT2; Breast cancer; Tissue array; CAM; VEGF; CCR4-Not complex; carbon catabolite repressed 4-negative on TATA-less complex; EGFR; epidermal growth factor receptor; HER2; human epidermal growth factor receptor 2; TNBC; triple negative breast cancers; VEG

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Structural and functional analysis of two novel somatostatin receptors identified from topmouth culter (Erythroculter ilishaeformis)

Keywords: HEK293; Human Embryonic Kidney 293; SSTRs; somatostatin receptors; mRNAs; messenger-ribonucleic acid; SS; Somatostatin; MC-LR; microcystin-LR; E2; 17β-estradiol; MCs; microcystins; DMSO; dimethyl sulfoxide; MS-222; methanesulfonate-222; cDNA; complementa

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Brazil nut improves the oxidative metabolism of superoxide-hydrogen peroxide chemically-imbalanced human fibroblasts in a nutrigenomic manner

Keywords: Val16Ala-SOD2 polymorphism; Selenium; Seleno-L-methionine; Paraquat; MnTBAP; Nutrigenomic effect; Ala; alanine; BN; Brazil nut; BNs; Brazil nuts; BNAE; Brazil nut aqueous extract; CAT; catalase (E.C. 1.11.1.6); DCFH-DA; 2′,7′-Dichlorodihydrofluorescei

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

Extra collagen overlay prolongs the differentiated phenotype in sandwich-cultured rat hepatocytes

Keywords: Bile canaliculi; Collagen; Hepatic drug disposition; Methods; Sandwich-cultured rat hepatocytes; AUC; Area Under the Curve; BEI; biliary excretion index; CDF; 5-(6)-carboxy-2-dichlorofluorescein; CDFDA; 5-(6)-carboxy-2-dichlorofluorescein diacetate; Clint

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

Cytoprotection of lipoic acid against toxicity induced by saxitoxin in hippocampal cell line HT-22 through in silico modeling and in vitro assays

Keywords: ARE; antioxidant response element; BBB; blood brain barrier; CNS; central nervous system; dc-STX; dc-saxitoxin; DFT; density functional simulation; DHLA; dihidrolipoic acid; DMEM; Dulbenco's Modified Eagles Medium containing high glucose; DMSO; dimetils

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

Fermented non-digestible fraction from combined nixtamalized corn (Zea mays L.)/cooked common bean (Phaseolus vulgaris L.) chips modulate anti-inflammatory markers on RAW 264.7 macrophages

Keywords: AA; acetic acid; ATCC; American Type Cell Culture; BA; butyric acid; DCF; digested chip fraction; DMSO; dimethyl sulfoxide; DMEM; Dulbecco's modified eagle medium; FNDCF; fermented non-digested chip fraction; GC-MS; gas chromatography-mass spectrometr

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

Tricyclic antidepressants inhibit hippocampal α7* and α9α10 nicotinic acetylcholine receptors by different mechanisms

Keywords: AChR; nicotinic acetylcholine receptor; ACh; acetylcholine; TCAs; tricyclic antidepressants; α-BTx; α-bungarotoxin; MLA; methyllycaconitine; RT; room temperature; IC50; ligand concentration that produces 50% inhibition (of binding or of agonist activati

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

Characterization of Superficial Dorsal Horn Neurons from “Tamamaki” Mice and Stability of their GAD67-EGFP Phenotype in Defined-Medium Organotypic Culture

Keywords: ACD; acid citrate dextrose; ACSF; artificial cerebrospinal fluid; BDNF; brain-derived neurotrophic factor; CSF 1; colony-stimulating factor; DMEM; Dulbecco's modified Eagle's medium; DMOTC; defined medium organotypic culture; EGFP; enhanced green fluore

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

Dibutyryl cAMP- or Interleukin-6-induced astrocytic differentiation enhances mannose binding lectin (MBL)-associated serine protease (MASP)-1/3 expression in C6 glioma cells

Keywords: Interleukin-6 (IL-6); 2′-O-Dibutyryl cAMP (dbcAMP); Mannose-binding lectin (MBL)-associated serine proteases (MASP)-1 and 3; C6 glioma cell line; Astrocytic differentiation; Glial fibrillary acidic protein (GFAP); CNS; central nervous system; GBM; gliob

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

Differential susceptibility of macrophages to serotype II feline coronaviruses correlates with differences in the viral spike protein

Keywords: APN; aminopeptidase N; CCoV; canine coronavirus; CoV; coronavirus; DMEM; Dulbecco's modified Eagle's medium; FCoV; feline coronavirus; FCS; fetal calf serum; FCWF; Felis catus whole fetus; FECV; feline enteric coronavirus; FIPV; feline infectious peri

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Impaired oligodendrogenesis and myelination by elevated S100B levels during neurodevelopment

Keywords: Inflammatory injury; Neurodevelopment; Oligodendrogenesis; Receptor for advanced glycation end-products; S100B protein; BSA; Bovine serum albumin; CNS; Central nervous system; CSF; Cerebrospinal fluid; OCSC; Organotypic cerebellar slice cultures; DIV; Day

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

Degradation of fibrin-β amyloid co-aggregate: A novel function attributed to ubiquitin

Keywords: AD; Alzheimer disease; AFM; atomic force microscopy; CAA; cerebral amyloid angiopathy; CHCA; α-cyano-4-hydroxycinnamic acid; DAPI; 4′,6-diamidino-2-phenylindole; DMEM; Dulbecco's modified eagle medium; DMSO; dimethyl sulfoxide; ELISA; enzyme-linked imm

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Combining mouse embryonic stem cells and zebrafish embryos to evaluate developmental toxicity of chemical exposure

Keywords: α/β-Cardiac Myosin; Heavy chain Alpha and Beta Cardiac Myosin; ABCG2; ATP-Binding Cassette sub-family G member 2; ANOVA; Analysis of Variance; DMEM; Dulbecco's Modified Eagle Medium; DMSO; Dimethyl Sulfoxide; DPBS; Dulbecco's Phosphate-Buffered Sali

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Downregulation of microRNA-370 in esophageal squamous-cell carcinoma is associated with cancer progression and promotes cancer cell proliferation via upregulating PIN1

Keywords: EC; esophageal cancer; ESCC; esophageal squamous-cell carcinoma; EA; esophageal adenocarcinoma; PIN1; Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1; RUX3; runt-related transcription factor 3; UTR; untranslated region; qRT-PCR; quantitative real-t

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Agmatine potentiates neuroprotective effects of subthreshold concentrations of ketamine via mTOR/S6 kinase signaling pathway

Keywords: Agmatine; Akt; HT22; Ketamine; Neuroprotection; p70S6 kinase; PSD95; 4E-BPs; 4E binding proteins; ANOVA; analysis of variance; DMEM; Dulbecco's Modified Eagle Medium; ECT; electroconvulsive therapy; CUS; chronic unpredictable stress; FST; forced swim test

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Fisetin Exerts Antioxidant and Neuroprotective Effects in Multiple Mutant hSOD1 Models of Amyotrophic Lateral Sclerosis by Activating ERK

Keywords: ALS; amyotrophic lateral sclerosis; AD; Alzheimer's disease; CAT; catalase; ChAT; choline acetyltransferase; CNS; central nervous system; CCK8; cell-counting kit 8; CMC; carboxymethyl cellulose; DAPI; 4,6-diamino-2-phenylindole; DHE; dihydroethidium; DM

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

New insights about the peculiar role of the 28-38 C-terminal segment and some selected residues in PACAP for signaling and neuroprotection

Keywords: ACN; acetonitrile; BBB; bloodbrain barrier; Bip; biphenylalanine; Boc; tert-butoxycarbonyl; BOP; (benzotriazol-1-yloxy)tris(dimethylamino) phosphonium hexafluorophosphate; BRET; bioluminescence resonance energy transfer; CHO cells; Chinese hamster ovary c

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2018 سفارش ترجمه

Supramolecular zippers elicit interbilayer adhesion of membranes producing cell death

Keywords: Fibroblasts; Mitochondria; Giant vesicles; H-aggregate; NAO; 2P-FLIM; two-photon fluorescence-lifetime imaging microscopy; AO; acridine orange; ATP; adenosine triphosphate; CL; cardiolipin; DFT; density functional theory; DMEM; Dulbecco Modified Eagle Med

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2018 سفارش ترجمه

Astrocyte elevated gene-1 is a novel regulator of astrogliosis and excitatory amino acid transporter-2 via interplaying with nuclear factor-κB signaling in astrocytes from amyotrophic lateral sclerosis mouse model with hSOD1G93A mutation

Keywords: ALS; Amyotrophic lateral sclerosis; AEG-1; Astrocyte elevated gene-1; ACM; astrocyte-conditioned medium; CBP; CREB-binding protein; COX-2; Cyclooxygenase-2; DMSO; dimethyl sulfoxide; DL-NBP; DL-3-n-butylphthalide; DMEM; Dulbecco modified Eagle medium; EAA

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2018 سفارش ترجمه

Differential expression of miR-34a, miR-141, and miR-9 in MPP+-treated differentiated PC12 cells as a model of Parkinson's disease

Keywords: AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; BCL2; B-cell lymphoma 2; BDNF; brain-derived neurotrophic factor; DAVID; database annotation, visualization, and integrated discovery; DCF; 2′,7′-dichlorofluorescin; GAPDH; glyceraldehyde 3-

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

The activation of STIM1 mediates S-phase arrest and cell death in paraquat induced acute lung intoxication

Keywords: ALI; acute lung injury; 2-APB; 2-Aminoethoxydiphenyl borate; BSA; bovine serum albumin; CCNA/CCND/Cyclin A/D; mammalian A/D-type Cyclin; CDK; Cyclin dependent kinase; CKI; Cyclin dependent kinase inhibitor; CRISPR-CAS9; clustered regularly interspaced sho

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Impact of glutathione modulation on the toxicity of the Fusarium mycotoxins deoxynivalenol (DON), NX-3 and butenolide in human liver cells

Keywords: 2-VP; 2-vinylpyridine; BSO; l-buthionine sulfoximine; BUT; butenolide; CDDO-Im; 1[2-cyano-312-dioxooleana-1,9(11)-dien-28-oyl]imidazolide; CTG; CellTracker™ Green; DCF; 2′7′-dichlorofluorescein; DMEM; Dulbecco's Modified Eagle Medium; DON; deoxyni

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Pre-clinical and translational pharmacology of a human interleukin-22 IgG fusion protein for potential treatment of infectious or inflammatory diseases

Keywords: AUClast; Area under concentration-time curve; CL; Total clearance; COLO205; Intestinal epithelial cells; Cmax; Maximal serum concentration; DC; Dendritic Cells; DMEM; Dulbecco's modified Eagle's medium; DSS; Dextran sulfate sodium salt; EC50; Half max

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Millettia macrophylla (Fabaceae) phenolic fraction prevents differentiation of 3T3-L1 adipocytes and the increased risks of cardiovascular diseases in ovariectomized rats

Keywords: CS; calf serum; DCM; dichloromethane; DMEM; Dulbecco's Modified Eagle Medium; DMSO; dimethylsulfoxide; DEX; dexamethasone; E2V; Estradiol valerate; ER; estrogen receptor; ERT; estrogen replacement therapy; IBMX; 3-isobutyl-1-methylxanthine; PF; phenolic f

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Chemical characterization and cerebroprotective effect of methanolic root extract of Colebrookea oppositifolia in rats

Keywords: MeCO; methanolic root extract of Colebrookea oppositifolia; I/R; ischemia reperfusion; DPPH; 2, 2-diphenyl-L-picrylhydrazyl; FRAP; ferric reducing antioxidant power; ORAC; oxygen radical absorbance capacity; LPS; lipopolysaccharide; LC-MS/MS; liquid chrom

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Effect of perfluorooctane sulphonate-induced Kupffer cell activation on hepatocyte proliferation through the NF-κB/TNF-α/IL-6-dependent pathway

Keywords: PFOS; Kupffer cells; Inflammation; Hepatocyte proliferation; NF-κB/ TNF-?/IL-6; ALT; alanine aminotransferase; AST; aspartate transaminase; APAP; acetaminophen; CCl4; carbon tetrachloride; CHE; cholinesterase; CM; conditioned media; CyD1; Cyclin D1; DAPI

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2018 سفارش ترجمه

Secretome from hypoxia-conditioned adipose-derived mesenchymal stem cells promotes the healing of gastric mucosal injury in a rodent model

Keywords: ADMSCs; adipose-derived mesenchymal stem cells; COX2; cyclooxygenase 2; PGE2; prostaglandin E2; ErK1/2; extracellular signal-regulated kinase 1/2; MAPK; mitogen-activated protein kinase; GI; gastrointestinal; HPO CM; hypoxic-conditioned medium; Nor CM; no

دانلود رایگان متن کامل مقاله ISI 50 صفحه سال انتشار : 2018 سفارش ترجمه

Neuroanatomical distribution and function of the vasopressin V1B receptor in the rat brain deciphered using specific fluorescent ligands

Keywords: ACTH; adrenocorticotropic hormone; AVP; arginine8 vasopressin; AC; adenylyl cyclase; BSA; bovine serum albumin; CaMKII; calmoduline-dependent serine/threonine kinase II; CHO; chinese hamster ovary; DG; dentate gyrus; DMEM; Dulbecco's modified Eagles'

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2018 سفارش ترجمه

A transcriptomic analysis of black cohosh: Actein alters cholesterol biosynthesis pathways and synergizes with simvastatin

Keywords: Actein; Black cohosh; Microarrays; Ranunculaceae; Simvastatin; Triterpene glycoside; CI; Combination Index; CYP; Cytochrome P450; DMSO; dimethylsulfoxide; DMEM; Dulbecco's Modified Eagle's medium; ERK; Extracellular signal related kinase; EtOH; ethanol; F

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2018 سفارش ترجمه

Design, synthesis and biological screening of 2-aminobenzamides as selective HDAC3 inhibitors with promising anticancer effects

Keywords: B16F10; murine melanoma cells; CDCl3; deuterated chloroform; CTCL; cutaneous T-cell lymphoma; DCM; dichloromethane; DFT; density functional theory; DMAP; 4-Dimethylaminopyridine; DMEM; Dulbecco's modified Eagle's media; DMF; dimethylformamide; DMSO; dimet

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2018 سفارش ترجمه

Trehalose protects against oxidative stress by regulating the Keap1-Nrf2 and autophagy pathways

Keywords: ATG; autophagy-related gene; DMEM; Dulbecco's Modified Eagle Medium; GFP; green fluorescent protein; HFD; high fat diet; Ho-1; heme oxygenase-1; Keap1; Kelch-like ECH-associated protein 1; LC3; microtubule-associated protein 1 light chain 3 (MAP1LC3); MCP

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2018 سفارش ترجمه

Effects of Mg2+ on recovery of NMDA receptors from inhibition by memantine and ketamine reveal properties of a second site

Keywords: NMDA receptors; Channel block; Memantine; Ketamine; DMEM; Dulbecco's modified Eagle medium; Glu; glutamate; HEK 293; human embryonic kidney cell line; Icontrol; current in control condition; ISSI; glutamate-activated current used to assess second site inh

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2018 سفارش ترجمه

Probing the binding site of novel selective positive allosteric modulators at the M1 muscarinic acetylcholine receptor

Keywords: ACh; acetylcholine; mAChR; muscarinic acetylcholine receptor; GPCR; G protein-coupled receptor; AD; Alzheimer's disease; PAM; positive allosteric modulator; NAM; negative allosteric modulator; TM; transmembrane domain; ECL; extracellular loop; CHO; Chin

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2018 سفارش ترجمه

Design, synthesis and biological evaluation of a novel tubulin inhibitor 7a3 targeting the colchicine binding site

Keywords: Tubulin inhibitor; Colchicine binding site; Combretastatin A-4; Pyrazole analogue; Anti-tumour; Co-crystal structure; ABC; ATP-binding cassette; P-gp; P-glycoprotein; MRP; multidrug resistant proteins; CA-4; combretastatin A-4; SARs; structure-activity re

دانلود رایگان متن کامل مقاله ISI 55 صفحه سال انتشار : 2018 سفارش ترجمه

Uveal melanocytes express high constitutive levels of MMP-8 which can be upregulated by TNF-α via the MAPK pathway

Keywords: Uveal melanocyte; MMP-8; TNF-α; JNK; ERK; Uveal melanoma; DMEM; Dulbecco's modified Eagle's medium; ECM; extracellur matrix; ERK; extracellular signal-regulated kinases; FBS; fetal bovine serum; JNK; c-Jun N-terminal kinase; MAPK; mitogen-activated prote

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2018 سفارش ترجمه

Levo-corydalmine alleviates vincristine-induced neuropathic pain in mice by inhibiting an NF-kappa B-dependent CXCL1/CXCR2 signaling pathway

Keywords: Vincristine; CXCL1; NF-kappa B (NFκB); CXCR2; Neuropathic pain; l-CDL; levo-corydalmine; l-THP; levo-tetrahydropalmatine; Oxy; Oxycodone; VCR; vincristine; NFκB; nuclear factor kappa B; TNF-α; tumor necrosis factor-alpha; IL-6; Interleukine-6; IL-1β;

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2018 سفارش ترجمه

TRAF3IP2 mediates TWEAK/TWEAKR-induced pro-fibrotic responses in cultured cardiac fibroblasts and the heart

Keywords: Fn14; CIKS; Act1; adverse cardiac remodeling; migration; Act1; NF-kappa B Activator 1; ANP; atrial natriuretic peptide; AP-1; activator protein-1; CCL; C-C Motif Chemokine Ligand; CD; Cluster of Differentiation; CF; cardiac fibroblasts; CIKS; Connection t

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2018 سفارش ترجمه

An in vitro and in vivo study of a 4-herb formula on the management of diet-induced metabolic syndrome

Keywords: Metabolic syndrome; Non-alcoholic fatty liver; Schisandrae Fructus; Crataegus Fructus; Momordica charantia; Milk thistle; ANOVA; analysis of variance; BBMV; brush border membrane vesicle; CP; Chinese Pharmacopoeia; CUHK; The Chinese University of Hong Kon

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2018 سفارش ترجمه

Aberrant regulation of the Akt signaling network by human cytomegalovirus allows for targeting of infected monocytes

Keywords: Cytomegalovirus; Monocytes; Small-molecule inhibitor; HCMV; human cytomegalovirus; h; hour; EGF; epidermal growth factor; EGFR; EGF receptor; αvβ3; alpha v beta 3 integrin; gB; glycoprotein B; gH; glycoprotein H; PI3K; phosphoinositide 3-kinase; PTEN; p

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2018 سفارش ترجمه

PD-L1 confers glioblastoma multiforme malignancy via Ras binding and Ras/Erk/EMT activation

Keywords: BLI; bioluminescence imaging; BSA; bovine serum albumin; CTL; cytotoxic T lymphocytes; CRISPR/Cas; Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR associated nucleases; DEGs; differently expressed genes; DMEM; Dulbecco's modified Eagle's

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2018 سفارش ترجمه

Activation of NPY-Y2 receptors ameliorates disease pathology in the R6/2 mouse and PC12 cell models of Huntington's disease

Keywords: Aβ; beta-amyloid; ABC; avidin-biotin complex; BBB; blood brain barrier; BDNF; brain derived neurotrophic factor; BSA; bovine serum albumin; CREB; cAMP response element binding protein; cDNA; complementary deoxyribonucleic acid; DAB, 3; 3-diaminobenzidine

دانلود رایگان متن کامل مقاله ISI 59 صفحه سال انتشار : 2018 سفارش ترجمه

Copper(II) complexes of N3O tripodal ligands appended with pyrene and polyamine groups: Anti-proliferative and nuclease activities

Keywords: Boc; tert-ButylOxyCarbonyl; CT; Charge Transfer; CT DNA; Calf Thymus DeoxyriboNucleic Acid; CV; Cyclic Voltammetry; DFT; Density Functional theory; DMEM; Dulbecco's Modified Eagle's Medium; DMF; N,N-dimethylformamide; DMSO; dimethylsulfoxide; DNA; Deoxyri

دانلود رایگان متن کامل مقاله ISI 59 صفحه سال انتشار : 2018 سفارش ترجمه

The utility of HepaRG cells for bioenergetic investigation and detection of drug-induced mitochondrial toxicity

Keywords: Mitochondria; Drug-induced liver injury; HepaRG; Seahorse; Glucose/galactose; Bioenergetic phenotype; ALR; ATP-linked respiration; BCA; bicinchoninic Acid; BR; basal respiration; CCCP; cyanide m-chlorophenyl hydrazine; CPT; carnitine palmitoyl transferase

دانلود رایگان متن کامل مقاله ISI 61 صفحه سال انتشار : 2018 سفارش ترجمه

Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents

Keywords: 1,4-Diaryl-2-azetidinone; Combretastatin A-4; Tubulin polymerization; Antitumor; SAR; structure-activity relationship; DABCO; 1,4-diazabicyclo[2.2.2]octane; TBAF; tetrabutylammonium fluoride; NMO; 4-methylmorpholine N-oxide; TBAB; tetrabutylammonium bromi

دانلود رایگان متن کامل مقاله ISI 91 صفحه سال انتشار : 2018 سفارش ترجمه