Keywords: DNA دو رشته شکسته; GO; Gene Ontology; EXP; Inferred from Experiment; IDA; Inferred from Direct Assay; IPI; Inferred from Physical Interaction; IMP; Inferred from Mutant Phenotype; IGI; Inferred from Genetic Interaction; IEP; Inferred from Expression Pattern; DEGs; different
مقالات ISI DNA دو رشته شکسته (ترجمه نشده)
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Keywords: DNA دو رشته شکسته; ZEA; Mouse; Meiotic entry; DNA double-strand breaks; Primordial follicle assembly;
Keywords: DNA دو رشته شکسته; Radiation therapy; Radiation toxicity; Radiation late effects; Radiogenomics; Bioinformatics; BER; base excision repair; DSB; DNA double-strand breaks; DSBR; DNA double-strand break repair; ECM; extracellular matrix; HR; homologous recombination; IR; ioni
Keywords: DNA دو رشته شکسته; Fhit; Wwox; Chromosome fragile site; Genome caretaker; DNA double-strand breaks;
Keywords: DNA دو رشته شکسته; ADH; alcohol dehydrogenase; BSA; bovine serum albumin; C60HyFn; hydrated C60 fullerene; CNTs; carbon nanotubes; DF-1; dendro[C60]fullerene-1; DRF; dose reducing factor; DSBs; DNA double-strand breaks; DU145; prostatic adenocarcinoma cell line; ESR; electr
Keywords: DNA دو رشته شکسته; Induced pluripotent stem cells; Small molecules; Genomic stability; DNA double-strand breaks;
Keywords: DNA دو رشته شکسته; Proton microbeam; DNA double-strand breaks; γ-H2AX; Bystander cross-talk; Gap junctional intercellular communication; Human lung cancer and normal fibroblast cells
Keywords: DNA دو رشته شکسته; ATM; ataxia telangiectasia-mutated kinase; ATR; ataxia telangiectasia and Rad3-related kinase; CI; combination index; CLL; chronic lymphocytic leukemic cells; DNA-PK; DNA-dependent protein kinase; DNA-PKcs; DNA-dependent protein kinase catalytic subunit;
Keywords: DNA دو رشته شکسته; γ-H2AX; gamma-H2AX; 8-OH-dG; 8-hydroxyguanosine; ANOVA; analysis of variance; BAL; bronchoalveolar lavage; DSB; DNA double-strand breaks; LDH; lactate dehydrogenase; MNP; microscale and nanoscale particles; NO; nitric oxide; OGG1; 8-oxoguanine DNA glycos
Keywords: DNA دو رشته شکسته; γH2AX foci; DNA double-strand breaks; 3rd generation dual-source CT; X-rays
Induction of DNA double-strand breaks in human gingival fibroblasts by eluates from titanium dioxide modified glass ionomer cements
Keywords: DNA دو رشته شکسته; Titanium dioxide; Glass-ionomer cement; DNA double-strand breaks; Nanoparticle; Micro-particle; γ-H2AX immunofluorescence assay;
Cytotoxicity and DNA double-strand breaks in human gingival fibroblasts exposed to eluates of dental composites
Keywords: DNA دو رشته شکسته; DNA double-strand breaks; γ-H2AX; Multiple components; Elution; Cytotoxicity; Genotoxicity; TEGDMA; Culture medium; DMEM;
The functional roles of PML nuclear bodies in genome maintenance
Keywords: DNA دو رشته شکسته; PML-NB; promyelocytic leukemia nuclear body; DSBs; DNA double-strand breaks; HR; homologous recombination; APL; acute promyelocytic leukemia; ALT; alternative lengthening of telomere; APB; ALT-associated PML bodies; PML nuclear body; SUMOylation; DNA repa
Caspase-mediated cleavage of X-ray repair cross-complementing group 4 promotes apoptosis by enhancing nuclear translocation of caspase-activated DNase
Keywords: DNA دو رشته شکسته; XRCC4; X-ray repair cross-complementing group 4; STS; staurosporine; CAD; caspase-activated DNase; ICAD; inhibitor of CAD; SRSF; serine/arginine-rich splicing factor; SRPK; SR protein kinase; Bcl; B-cell lymphoma; CLK; Cdc2-like kinase; Lig4; DNA ligase I
Resveratrol represses estrogen-induced mammary carcinogenesis through NRF2-UGT1A8-estrogen metabolic axis activation
Keywords: DNA دو رشته شکسته; 2-MeOE1/E2; 4-MeOE1/E2, methoxyestrogens; 2-OHE1/E2; 4-OHE1/E2, hydroxyestrogens; 53BP1; tumor protein p53 binding protein 1; DMBA; 7,12-dimethylbenz(a)anthracene; DSBs; DNA double-strand breaks; E1; estrone; E2; estradiol; E2-3G; E2-3-glucuronide; E2-17G
Increase of DNA damage and alteration of the DNA damage response in myelodysplastic syndromes and acute myeloid leukemias
Keywords: DNA دو رشته شکسته; Myelodysplastic syndromes; Acute myeloid leukemias; Genetic instability; DNA double-strand breaks; DNA damage response;
Measurement of DNA damage in peripheral blood by the γ-H2AX assay as predictor of colorectal cancer risk
Keywords: DNA دو رشته شکسته; DSBs; DNA double-strand breaks; PBLs; peripheral blood lymphocytes; CRC; colorectal cancer; IR; ionizing radiation; ORs; odds ratios; BMI; body mass index; HR; homologous recombination; NHEJ; non-homologous end joining; Gamma H2AX; Colorectal cancer risk;
ReviewBalancing act: To be, or not to be ubiquitylated
Keywords: DNA دو رشته شکسته; DNA double-strand breaks; DNA damage response; DNA repair; Ubiquitylation; Deubiquitylation;
Cytotoxicity and genotoxicity effects of arsenic trioxide on SQ20B human laryngeal carcinoma cells
Keywords: DNA دو رشته شکسته; Arsenic trioxide; DNA damage; Head and neck carcinoma cells; γH2AX; DNA double-strand breaks; Apoptosis;
Original ArticleHDAC4 and HDAC6 sustain DNA double strand break repair and stem-like phenotype by promoting radioresistance in glioblastoma cells
Keywords: DNA دو رشته شکسته; HDAC4; HDAC6; Glioblastoma; Radiotherapy; Radioresistance; GBM; glioblastoma; TMZ; temozolomide; RT; radiotherapy; HDACs; Histone deacetylases; HATs; Histone acetyltransferases; DSBs; DNA double-strand breaks; OS; Overall survival; shRNA; short hairpin RN
Interaction of Quindoline derivative with telomeric repeat-containing RNA induces telomeric DNA-damage response in cancer cells through inhibition of telomeric repeat factor 2
Keywords: DNA دو رشته شکسته; ALT; alternative lengthening of telomeres; ATM; ataxia telangiectasia mutated; CD; circular dichroism; ChIP; chromatin immunoprecipitation; DAPI; 4â²,6-diamidino-2-phenylindole; DDR; DNA damage response; DMSO; dimethyl sulfoxide; DSBs; DNA double-strand
Improved selectivity and cytotoxic effects of irinotecan via liposomal delivery: A comparative study on Hs68 and HeLa cells
Keywords: DNA دو رشته شکسته; Irinotecan; Liposomes; Cytotoxicity; Drug uptake; Apoptosis; Growth arrest; DNA double-strand breaks;
ReviewTranscription and DNA Damage: Holding Hands or Crossing Swords?
Keywords: DNA دو رشته شکسته; DSBs; DNA double-strand breaks; DDR; DNA damage response; MRN; MRE11-RAD50-NBS1; ATM; ataxia telangiectasia mutated; MDC1; mediator of DNA-damage checkpoint; 53BP1; p53-binding protein; NHEJ; non-homologous end joining; ncRNA; non-coding RNA; HR; homo
Interstrand Crosslink Repair as a Target for HDAC Inhibition
Keywords: DNA دو رشته شکسته; chloroethylnitrosoureas; DNA double-strand breaks; HDAC; homologous recombination; interstrand crosslink repair; platinum compounds;
Role of RAD51AP1 in homologous recombination DNA repair and carcinogenesis
Keywords: DNA دو رشته شکسته; Homologous recombination; DNA repair; Cancer; DNA double-strand breaks; Replication; Genome stability; RAD51AP1; Cancer therapy;
From intronization to intron loss: How the interplay between mRNA-associated processes can shape the architecture and the expression of eukaryotic genes
Keywords: DNA دو رشته شکسته; Splicing; Cleavage and polyadenylation; Intronization; Intron loss; U1 snRNP; DNA double-strand breaks; R loops; Promoter directionality; U1-dependent definition;
DNA End Resection: Facts and Mechanisms
Keywords: DNA دو رشته شکسته; DNA end resection; Homologous recombination; DNA double-strand breaks; Chromatin remodeling factors; Genome stability
Lysines 3241 and 3260 of DNA-PKcs are important for genomic stability and radioresistance
Keywords: DNA دو رشته شکسته; DNA double-strand breaks; Non-homologous end-joining; Acetylation; DNA-PKcs;
Dynamic monitoring of oxidative DNA double-strand break and repair in cardiomyocytes
Keywords: DNA دو رشته شکسته; DNA double-strand breaks; H2O2; Cultured neonatal rat cardiomyocytes; DNA damage; Oxidative stress; Heart;
Effets de répétitions de doses d’irradiation et réparation de l’ADN : importance du facteur individuel et de l’intervalle de temps entre les doses
Keywords: DNA دو رشته شکسته; Répétition de doses; Fractionnement; Réparation de l’ADN; Radiosensibilité; Cassures double-brinRepeated doses; Fractionation; DNA repair; Radiosensitivity; DNA double-strand breaks
Agammaglobulinemia associated to nasal polyposis due to a hypomorphic RAG1 mutation in a 12 years old boy
Keywords: DNA دو رشته شکسته; PID; primary immune deficiency; SCID; severe combined immunodeficiency; CVID; common variable immunodeficiency; OS; Omenn syndrome; RAG1; recombination-activating gene 1; RAG2; recombination-activating gene 2; RSSs; recombination signal sequences; DSBs; D
House dust mite-induced asthma causes oxidative damage and DNA double-strand breaks in the lungs
Keywords: DNA دو رشته شکسته; House dust mite; asthma; oxidative stress; DNA double-strand breaks; BEAS-2B; cell death; DNA repair; NU7441; AHR; Airway hyperresponsiveness; ATM; Ataxia-telangiectasia mutated; BAL; Bronchoalveolar lavage; CC10; Club cell 10Â kDa protein; DCFH-DA; 2,7-D
Cancer TARGETases: DSB repair as a pharmacological target
Keywords: DNA دو رشته شکسته; DSB repair; Genome instability; Cancer; Kinases; Helicases; Nucleases; ALT; alternative telomere lengthening; AML; acute myeloid leukemia; A-T; ataxia-telangiectasia; ATM; ataxia-telangiectasia mutated; ATP; adenosine triphosphate; ATR; ataxia-tel
Assessment of DNA damage associated with standard or contrast diagnostic echocardiography
Keywords: DNA دو رشته شکسته; DNA double-strand breaks; Stress-echocardiography; Contrast-echocardiography; Safety; Coronary artery disease;
Disruption of lig4 improves gene targeting efficiency in the oleaginous fungus Mortierella alpina 1S-4
Keywords: DNA دو رشته شکسته; HR; homologous recombination; NHEJ; none homologousend joining; DSBs; DNA double-strand breaks; OA; oleic acid; LA; linoleic acid; GLA; γ-linolenic acid; DGLA; dihomo-γ-linolenic acid; ARA; arachidonic acid; DNA ligase 4 (lig4); Homologous recombination
Anthracyclines induce double-strand DNA breaks at active gene promoters
Keywords: DNA دو رشته شکسته; DNA double-strand breaks; Doxorubicin; Etoposide; Nucleosome turnover; Squamous cell carcinoma;
New mechanism of γ-H2AX generation: Surfactant-induced actin disruption causes deoxyribonuclease I translocation to the nucleus and forms DNA double-strand breaks
Keywords: DNA دو رشته شکسته; Nonylphenol polyethoxylates; Deoxyribonuclease I; Actin; DNA double-strand breaks; γ-H2AX; Surfactants;
Dental composite components induce DNA-damage and altered nuclear morphology in gingiva fibroblasts
Keywords: DNA دو رشته شکسته; Dental composites; Monomers; Chromatin; Gingiva fibroblasts; DNA damage; Nuclear morphology; DNA double-strand breaks; γ-H2AX; 53BP1;
Platinum-induced kidney damage: Unraveling the DNA damage response (DDR) of renal tubular epithelial and glomerular endothelial cells following platinum injury
Keywords: DNA دو رشته شکسته; ApG; adenine-guanine; ATM; Ataxia telangiectasia mutated; ATR; ATM and Rad3 related kinase; Bax; Bcl2-associated X protein; Bcl2; B-cell CLL/lymphoma 2; EdU; 5-ethynyl-2â²-deoxyuridine; CarboPt; carboplatin; CENP-F; centromere protein F; Chk1; checkpoint
TIPIN depletion leads to apoptosis in breast cancer cells
Keywords: DNA دو رشته شکسته; Apoptosis; Basal-like; Replicative stress; Therapeutic target; TIPIN; Triple-negative breast cancer; 2D; 2-dimensional; 3D; 3-dimensional; BC; breast cancer; BrdU; 5-bromo-2â²-deoxyuridine; CldU; 5-chloro-2â²-deoxyuridine; CN; copy number; DSBs; DNA dou
Manipulation of epigenetic factors and the DNA repair machinery for improving the frequency of plant transformation
Keywords: DNA دو رشته شکسته; C-NHEJ; canonical NHEJ; DSBs; DNA double-strand breaks; gDNA; genomic DNA; GT; gene targeting; HR; homologous recombination; NHEJ; non-homologous end joining; PTGS; posttranscriptional gene silencing; RNAi; RNA interference; rat; resistant to Agrobacteriu
Even low doses of radiation lead to DNA damage accumulation in lung tissue according to the genetically-defined DNA repair capacity
Keywords: DNA دو رشته شکسته; DNA double-strand breaks; Low-dose radiation; Normal tissue toxicity; Lung tissue; 53BP1 foci; Non-homologous end-joining;
Downregulation of Rad51 participates in OTA-induced DNA double-strand breaks in GES-1 cells in vitro
Keywords: DNA دو رشته شکسته; Rad51; Ochratoxin A; Homologous recombination repair pathway; DNA double-strand breaks; Cell cycle arrest; Human gastric epithelium immortalized cell;
Protein kinase CK2 is required for the recruitment of 53BP1 to sites of DNA double-strand break induced by radiomimetic drugs
Keywords: DNA دو رشته شکسته; DSBs; DNA double-strand breaks; NHEJ; non-homologous end-joining; HR; homologous recombination; NCS; neocarzinostatin; ATM; ataxia telangiectasia mutated; MDC1; mediator of DNA damage checkpoint; 53BP1; p53-binding protein 1; BRCA1; breast cancer type 1 s
Should I stay or should I go: VCP/p97-mediated chromatin extraction in the DNA damage response
Keywords: DNA دو رشته شکسته; CPDs; Cyclobutane pyrimidine dimers; DSBs; DNA double-strand breaks; ER; endoplasmic reticulum; ERAD; ER-associated degradation; HR; homologous recombination; 6-4PPs; pyrimidine-pyrimidone [6-4] photoproducts; IR; ionizing radiation; UBD; ubiquitin-bindin
Histone deacetylase inhibitors potentiate photochemotherapy in cutaneous T-cell lymphoma MyLa cells
Keywords: DNA دو رشته شکسته; Phototherapy; Iodinated DNA ligand; Histone deacetylases; Histone deacetylase inhibitors; Cutaneous T-cell lymphoma; DNA double-strand breaks
Distinct mechanisms of cell-kill by triapine and its terminally dimethylated derivative Dp44mT due to a loss or gain of activity of their copper(II) complexes
Keywords: DNA دو رشته شکسته; Triapine (3-AP, 3-aminopyridine-2-carboxaldehyde thiosemicarbazone); Dp44mT (di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone); Metal coordination; DNA replication stress; DNA double-strand breaks; Reactive oxygen species;
Cytolethal distending toxin (CDT) is a radiomimetic agent and induces persistent levels of DNA double-strand breaks in human fibroblasts
Keywords: DNA دو رشته شکسته; Cytolethal distending toxin; DNA double-strand breaks; DNA damage response; DNA repair; Gamma irradiation;
Repair effects of exogenous SOD on Bacillus subtilis against gamma radiation exposure
Keywords: DNA دو رشته شکسته; Superoxide dismutase; Bacillus subtilis var. niger; Repair effect; DNA double-strand breaks;
Elevated Rad53 kinase activity influences formation and interhomolog repair of meiotic DNA double-strand breaks in budding yeast
Keywords: DNA دو رشته شکسته; DSBs; DNA double-strand breaks; CO; crossover; NCO; non-crossover; UTR; untranslated region; TCA; trichloroacetic acid; ISA; in situ autophosphorylation; KD; kinase dead; MI; meiosis I; MII; meiosis II; DAPI; 4â²,6-diamidino-2-phenylindole; Rad53; DNA do