دانلود مقالات ISI درباره داکت + ترجمه فارسی

Chemical modifications of the N-methyl-laudanosine scaffold point to new directions for SK channels exploration

Keywords: داکت; Docking; Rational design; Butanamide; Benzyloxy; Enantiomers; Small conductance calcium-activated K+ channels; Apamin; In vitro binding; Isoquinoline;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Antimalarial activity of HIV-1 protease inhibitor in chromone series

Keywords: داکت; Antimalarial activity; Plasmepsin II; Chromone series; Docking

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Identification of novel cyanobacterial compounds for oral disease through in vitro and insilico approach

Keywords: داکت; Cyanobacteria; Bioactive compounds; Candidiasis; GC-MS; Docking; Oral diseases

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Involvement of non-polyalanine (polyA) residues in aggregation of polyA proteins: Clue for inhibition of aggregation

Keywords: داکت; PolyA aggregation; Hydrophobic interaction; Docking; HSP40; HSP70

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

In silico identification of potent inhibitors of alpha-synuclein aggregation and its in vivo evaluation using MPTP induced Parkinson mice model

Keywords: داکت; Parkinson disease; Alpha-synuclein; ADME; Toxicity; Docking; CNB-001; MPTP

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Technical difficulties and innovation in the Jiangyin Yangtze River crossing project of 3300 m HDD

Keywords: داکت; Yangtze River; Natural gas pipeline; Crossing; Horizontal directional drilling (HDD); Docking; Long distance; Huge torque; Drilling in sand; Drilling mud recycle; Centrifugal

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

The interaction between organic phosphate ester and p53: An integrated experimental and in silico approach

Keywords: داکت; Organophosphate flame retardants (OPFRs); p53; Docking; Quantitative structure-activity relationship (QSAR); Binding affinity; Multiple linear regression (MLR);

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Synthesis of novel pyrazole–thiadiazole hybrid as potential potent and selective cyclooxygenase-2 (COX-2) inhibitors

Keywords: داکت; Pyrazoles; Thiadiazole; COX-1 and COX-2; Cytotoxicity; Docking; Drug likeness

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

fRMSDchiral: A novel algorithm to represent differences between positions of stereoisomers in complex with dissymmetric binding site

Keywords: داکت; Chiral recognition; Molecular modeling; Docking; Molecular dynamics; Fragment RMSD

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Flow synthesis and biological activity of aryl sulfonamides as selective carbonic anhydrase IX and XII inhibitors

Keywords: داکت; Carbonic anhydrases; Flow synthesis; Sulfonamides; Docking;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Potent angiotensin-converting enzyme inhibitory tripeptides identified by a computer-based approach

Keywords: داکت; ACE inhibition; Hypotensive peptides; Docking; Rational design; ADME prediction

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Mechanistic insights into mode of action of potent natural antagonists of BACE-1 for checking Alzheimer's plaque pathology

Keywords: داکت; BACE-1; Alzheimer's; Natural compound; High throughput virtual screening; Docking; Molecular dynamics simulation;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Molecular modeling and docking of novel laccase from multiple serotype of Yersinia enterocolitica suggests differential and multiple substrate binding

Keywords: داکت; Multicopper oxidase; Docking; Pathogenicity; Laccase; Yersinia enterocolitica;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

In silico study of 1-(4-Phenylpiperazin-1-yl)-2-(1H-pyrazol-1-yl) ethanones derivatives as CCR1 antagonist: Homology modeling, docking and 3D-QSAR approach

Keywords: داکت; CCR1; 3D-QSAR; Homology modeling; Receptor-guided CoMFA; Docking;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Reprint of: fRMSDchiral: A novel algorithm to represent differences between positions of stereoisomers in complex with dissymmetric binding site

Keywords: داکت; Chiral recognition; Molecular modeling; Docking; Molecular dynamics; Fragment RMSD;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Evaluation of (arene)Ru(II) complexes of curcumin as inhibitors of dipeptidyl peptidase IV

Keywords: داکت; Curcumin; Ruthenium complexes; Docking; AutoDock; Dipeptidyl peptidase-4 (DPPIV);

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Computational & experimental evaluation of the structure/activity relationship of β-carbolines as DYRK1A inhibitors

Keywords: داکت; DYRK1A; MAO-A; Pharmacophore; Docking; Inhibitor; β-Carboline; SAR

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Impact of the subtle differences in MMP-12 structure on Glide-based molecular docking for pose prediction of inhibitors

Keywords: داکت; MMP-12; PDB ID; Docking

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Ca2+-regulated secretory granule exocytosis in pancreatic and parotid acinar cells

Keywords: داکت; Pancreatic parotid acinar secretion; Acinar exocytosis; Membrane trafficking; Secretory granules; Zymogen granules; Synaptotagmin; Complexin; cAMP; Ca2+; SNARE; Tethering; Docking; Fusion

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Identification of novel inhibitors against Mycobacterium tuberculosisl-alanine dehydrogenase (MTB-AlaDH) through structure-based virtual screening

Keywords: داکت; Mycobacterium tuberculosis; l-Alanine dehydrogenase; Pharmacophore; Glide; Docking

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Lipase-catalyzed highly diastereoselective direct vinylogous Michael addition reaction of α,α-dicyanoolefins to nitroalkenes

Keywords: داکت; Biocatalytic promiscuity; Lipase; Vinylogous Michael addition; Vinyl malononitrile; Docking;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Molecular docking study, synthesis and biological evaluation of Schiff bases as Hsp90 inhibitors

Keywords: داکت; Hsp90; Schiff bases; Docking; Malachite green; MTT

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Probing the human estrogen receptor-α binding requirements for phenolic mono- and di-hydroxyl compounds: A combined synthesis, binding and docking study

Keywords: داکت; Estrogen receptor; Docking; Phenolic; Breast cancer; Endocrine disruptor;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

The biflavonoid morelloflavone inhibits the enzymatic and biological activities of a snake venom phospholipase A2

Keywords: داکت; Morelloflavone; Snakebite; Local tissue damage; Docking; Phospholipase A2;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Combined spectroscopic and molecular docking techniques to study interaction of Zn (II) DiAmsar with serum albumins

Keywords: داکت; Zn (II) DiAmsar; Serum albumin; Binding site; Docking;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Synthesis and evaluation of Strychnos alkaloids as MDR reversal agents for cancer cell eradication

Keywords: داکت; Total synthesis; Strychnos alkaloids; P-glycoprotein; ABCB1; Multidrug resistance; Resensitization; Docking;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Identification of a novel ATPase activity in 14-3-3 proteins - Evidence from enzyme kinetics, structure guided modeling and mutagenesis studies

Keywords: داکت; WT; wild-type; Ni-NTA; nickel-nitriloacetic acid; MALDI; matrix assisted laser desorption ionization; TOF; tandem time of flight; PDB; protein data bank; ATP-γ-S; adenosine 5′-(3-thiotriphosphate); AMP-PCP; adenylylmethylenediphosphonate; HEPES; 4-(2-h

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Identification of active site residues of Fenugreek β-amylase: Chemical modification and in silico approach

Keywords: داکت; β-Amylase; Active site; Chemical modification; Docking; Homology modelling; Trigonella foenum-graecum

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Docking of anti-HIV-1 oxoquinoline-acylhydrazone derivatives as potential HSV-1 DNA polymerase inhibitors

Keywords: داکت; Acylhydrazone; Dual antiviral agents; Docking; HIV-1; HSV-1; Molecular modeling

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Toward activated homology models of the human M1 muscarinic acetylcholine receptor

Keywords: داکت; G protein-coupled receptor; Homology modeling; Docking; Virtual screening; Activated structure

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

A selective, long-lived deep-red emissive ruthenium(II) polypyridine complexes for the detection of BSA

Keywords: داکت; Ruthenium(II) complex; Luminescence; Bovine serum albumin (BSA); Biosensor; Docking

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Design, synthesis, anticancer activity and docking studies of novel 4-morpholino-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidine derivatives as mTOR inhibitors

Keywords: داکت; 7,8-Dihydro-5H-thiopyrano[4,3-d]pyrimidine; Synthesis; Docking; mTOR; Antitumor activity;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Homology modelling, docking, pharmacophore and site directed mutagenesis analysis to identify the critical amino acid residue of PknI from Mycobacterium tuberculosis

Keywords: داکت; Protein kinases; Homology modelling; Site directed mutagenesis; Substrate; Docking; Pharmacophore analysis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

In silico investigation of medicinal spectrum of imidazo-azines from the perspective of multitarget screening against malaria, tuberculosis and Chagas disease

Keywords: داکت; Docking; Imidazo-azines; Ligand efficiency; Multitarget screening; Lead-likeness

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Design of the influenza virus inhibitors targeting the PA endonuclease using 3D-QSAR modeling, side-chain hopping, and docking

Keywords: داکت; Influenza virus endonuclease; 3D-QSAR; Docking; Side-chain hopping; Virtual screening;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Application of docking methods for metal chelate affinity precipitation of endo-glucanase using pH-response polymer

Keywords: داکت; Docking; Label-free detection; Metal chelate affinity precipitation; pH-response; Endo-glucanase;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Synthesis, spectral characterization and DNA binding of Schiff-base metal complexes derived from 2-amino-3-hydroxyprobanoic acid and acetylacetone

Keywords: داکت; Serine; Schiff-base complexes; Docking; DNA binding

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Organotin(IV) complexes of carboxylate derivative as potential chemotherapeutic agents against Leishmania

Keywords: داکت; Organotin(IV) carboxylate; Leishmania; DNA interaction; Docking; Apoptosis; Drug targeting dose–response

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

4-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-5(3)-(6-methylpyridin-2-yl)imidazole and -pyrazole derivatives as potent and selective inhibitors of transforming growth factor-β type I receptor kinase

Keywords: داکت; TGF-β; ALK5 inhibitor; Fibrosis; Cancer; Kinase assay; Cell-based luciferase reporter assay; Docking;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Inhibition of myeloperoxidase activity by the alkaloids of Peganum harmala L. (Zygophyllaceae)

Keywords: داکت; Peganum harmala; HPLC; β-Carboline alkaloids; Myeloperoxidase; Anti-inflammatory; Docking

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Exploring the structural basis of the selective inhibition of monoamine oxidase A by dicarbonitrile aminoheterocycles: Role of Asn181 and Ile335 validated by spectroscopic and computational studies

Keywords: داکت; MAO; monoamine oxidase; FAD; flavin adenine dinucleotide; QM/MM; quantum mechanics/molecular mechanics; Carbonitrile aminofuran; Monoamine oxidase; Selective binding; Docking; Molecular dynamics; Altered flavin spectrum;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Synthesis, molecular docking and biological evaluation of new steroidal 4H-pyrans

Keywords: داکت; 4H-pyran; Ethyl cyanoacetate; Anticancer; Docking; Comet assay;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

SAHA-based novel HDAC inhibitor design by core hopping method

Keywords: داکت; SAHA; Core hopping; Docking; ADMET; Molecular dynamics simulation;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Synthesis, docking simulation, biological evaluations and 3D-QSAR study of 5-Aryl-6-(4-methylsulfonyl)-3-(metylthio)-1,2,4-triazine as selective cyclooxygenase-2 inhibitors

Keywords: داکت; Cyclooxygenase; Inflammatory and analgesic properties; Docking; 3D-QSAR; 1,2,4-Triazine

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Insights into protein–TNS (2-p-toluidinylnaphthalene-6-sulfonate) interaction using molecular dynamics simulation

Keywords: داکت; TNS; Fluorescent dye; Simulation; Docking; Unfolded protein

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Genetic and structural insights into plasmid-mediated extended-spectrum β-lactamase activity of CTX-M and SHV variants among pathogenic Enterobacteriaceae infecting Indian patients

Keywords: داکت; ESBL; blaCTX-M; blaSHV; Protein stability; Docking; Hydrolytic activity

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Discovery of 2-pyridone derivatives as potent HIV-1 NNRTIs using molecular hybridization based on crystallographic overlays

Keywords: داکت; NNRTIs; HIV; Drug design; 2-Pyridone; Molecular hybridization; Docking

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Carbonic anhydrase inhibitors: Synthesis and inhibition of the human carbonic anhydrase isoforms I, II, IX and XII with benzene sulfonamides incorporating 4- and 3-nitrophthalimide moieties

Keywords: داکت; CA; carbonic anhydrase; hCA; human carbonic anhydrase; CAI; carbonic anhydrase inhibitor; SAR; structure-activity relationship; Zn; zinc; AZM; acetazolamide; MZA; methazolamide; EZA; ethoxzolamide; DCP; dibromophenamide; DZA; dorzolamide; BRZ; brinzolam

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Design, synthesis & evaluation of condensed 2H-4-arylaminopyrimidines as novel antifungal agents

Keywords: داکت; Antifungal activity; Condensed pyrimidines; Docking; Lanosterol 14-α-demethylase; MWI; SAR

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Setting the stage for electron transfer: Molecular basis of ABTS-binding to four laccases from Trametes versicolor at variable pH and protein oxidation state

Keywords: داکت; Laccase; Substrate; Sequence analysis; Docking; DFT

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه