دانلود مقالات ISI درباره Dsbs + ترجمه فارسی

تشخیص فیلوژنومیک و پیش بینی عملکردی ژن هایی که به طور بالقوه برای مایز گیاهی مهم هستند

Phylogenomic detection and functional prediction of genes potentially important for plant meiosis

Keywords: GO; Gene Ontology; EXP; Inferred from Experiment; IDA; Inferred from Direct Assay; IPI; Inferred from Physical Interaction; IMP; Inferred from Mutant Phenotype; IGI; Inferred from Genetic Interaction; IEP; Inferred from Expression Pattern; DEGs; different

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

وضعیت سلول های سرطانی درون سلولی، سلول های بنیادی سرطانی را در سلول های سرطانی تیروئید کنترل می کند

Intracellular redox status controls spherogenicity, an in vitro cancer stem cell marker, in thyroid cancer cell lines

Keywords: ALDH; aldehyde dehydrogenase; CSCs; cancer stem cells; Cis; cisplatin; DEAB; N,N-diethylaminobenzaldehyde; DCFAB; 2′,7′-dichlorofluorescin diacetate; Dox; doxorubicin; DSBs; DNA double strand breaks; DLL4; delta-like 4; EGF; epidermal growth factor; E

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

جلوگیری از آسیب تابشی توسط محصولات طبیعی

Prevention from radiation damage by natural products

Keywords: Cancer; Phytochemical; Radiotherapy; Radioprotection; Side effects; AP-1; activator protein-1; Bax; Bcl-2-associated X protein; Bcl-2; B-cell lymphoma 2; CAPE; caffeic acid phenylethylester; CAT; chloramphenicol acetyltransferase; CBMN; cytokinesis block

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

بررسی در مورد سرطان زایی آرسنیک: اپیدمیولوژی، متابولیسم، سمیت ژنتیکی و تغییرات اپی ژنتیکی

A review on arsenic carcinogenesis: Epidemiology, metabolism, genotoxicity and epigenetic changes

Keywords: Arsenic; Inorganic arsenic; Carcinogenesis; Epidemiology; Methylation; Signal transduction; As3MT; arsenic-3-methyl transferase enzyme; BER; base excision repair; CA; chromosomal aberration; DAPK; death-associated protein kinase; DMA; dimethylarsinous aci

دانلود رایگان متن کامل مقاله ISI 60 صفحه سال انتشار : 2018 سفارش ترجمه

بررسی اثرات سمی، سیتوتوکسی و ژنوتوسیک فیتول و نانو امولسیون آن

Evaluation of toxic, cytotoxic and genotoxic effects of phytol and its nanoemulsion

Keywords: Phytol nanoemulsion; Toxicogenetic effect; Adaptive response; ATM; ataxia telangiectasia-mutated; ATR; ataxia telangiectasia-mutated-Rad3-related kinase; Casp; caspase; CYP-c; cytochrome-c; DSBs; double strand breaks; EOs; essential oils; ERK; extracellul

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

پوشش ذرات، اما نه یون های نقره، سبب بروز ژن سمیت نانوذرات نقره ای در مدل موش می شود

Particle coatings but not silver ions mediate genotoxicity of ingested silver nanoparticles in a mouse model

Keywords: AgNPs; silver nanoparticles; cit; citrate; PVP; polyvinylpyrrolidone; AgOAc; silver acetate; Ag+;  silver ions; 8-oxoG; 7,8-dihydro-8-oxoguanine; γ-H2AX; phosphorylated histone 2AX; DSBs; double strand breaks; MN; micronuclei; SPR; surface plasmon reson

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

پس زدن به عنوان نقطه پایانی بیولوژیک پس از هدف گذاری فارماکولوژیک گیرنده های تیروزین کیناز در سرطان

Senescence as biologic endpoint following pharmacological targeting of receptor tyrosine kinases in cancer

Keywords: ATIR; anti-tumor immune response; ATM; ataxia telangiectasia mutated; CDK; cyclin-dependent kinase; CGH; comparative genomic hybridization; CHK1; checkpoint kinase 1; CHK2; checkpoint kinase 2; DDAs; DNA-damaging agents; DDR; DNA damage response; DSBs; do

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

کروموزوم هموئئولوژیک در سرتاسر فیلوژنتیک یوکاریوت جفت می شود

Homoeologous chromosome pairing across the eukaryote phylogeny

Keywords: ATP; adenosine triphosphate; DSBs; double strand breaks; MMR; mismatch repair; PCGs; pairing control genes; ROS; reactive oxygen species; WGD; whole genome duplication; Gene conversion; Homoeolog; Hybrid; Meiosis; Polyploid; Recombination;

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2017 سفارش ترجمه

کمبود اتوفابی در سلول های پیشکشی کبد منجر به نقص ساقه و افزایش حساسیت به تغییرات نئوپلاستی می شود

Autophagy-deficiency in hepatic progenitor cells leads to the defects of stemness and enhances susceptibility to neoplastic transformation

Keywords: HPCs; hepatic progenitor cells; mtROS; mitochondrial reactive oxygen species; DEN; diethylnitrosamine; SPCs; stem/progenitor cells; HSCs; hematopoietic stem cells; NSCs; neural stem cells; DMEM; Dulbecco's modified Eagle's medium; FBS; fetal bovine serum;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

رونویسی ترکیبی از نوترکیب هومولوگ پس از آسیب اکسیداتیو

Transcription-coupled homologous recombination after oxidative damage

Keywords: DSBs; double strand breaks; SSBs; single strand breaks; HR; homologous recombination; NHEJ; non-homologous end-joining; CSA; Cockayne syndrome protein A; CSB; Cockayne syndrome protein B; TC-NER; transcription-coupled nucleotide excision repair; TC-DSBR;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

نانوذرات کربنی به عنوان محافظهای احتمالی در سیستمهای بیولوژیکی

Carbon nanoparticles as possible radioprotectors in biological systems

Keywords: ADH; alcohol dehydrogenase; BSA; bovine serum albumin; C60HyFn; hydrated C60 fullerene; CNTs; carbon nanotubes; DF-1; dendro[C60]fullerene-1; DRF; dose reducing factor; DSBs; DNA double-strand breaks; DU145; prostatic adenocarcinoma cell line; ESR; electr

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2016 سفارش ترجمه

آنتی اکسیدان نیتروکسید به عنوان یک استراتژی بالقوه برای کاهش استرس اکسیداتیو / نیتروژنیک ناشی از پراکسید هیدروژن به همراه اکسید نیتریک در نورون های کشت شده

Nitroxide antioxidant as a potential strategy to attenuate the oxidative/nitrosative stress induced by hydrogen peroxide plus nitric oxide in cultured neurons

Keywords: Nitric oxide; H2O2; SNAP; Oxidative/nitrosative stress; Antioxidant; Neuron; 3-NT; 3-nitrotyrosine; ANOVA; one-way analysis of variance; CAT; catalase; CBA; Coumarin boronic acid; CNS; central nervous system; COH; hydroxycoumarin; DCFH-DA; 2′,7'-dichlor

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2016 سفارش ترجمه

بررسی استفاده از ویرایش ژنوم در مطالعه کاهش شنوایی

ReviewThe application of genome editing in studying hearing loss

Keywords: AAV; Adeno-associated virus; ARHL; age-related hearing loss; Cas9; CRISPR-associated nuclease 9; CRISPR; clustered, regularly interspaced, short palindromic repeat; crRNA; CRISPR RNA; dCas9; defective Cas9; DSBs; double-strand breaks; gRNA; guide RNA; HDR

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

وورتمنین اثر ترکیبی این اتوزوئید و سیس پلاتین را در سلول های گلیوما انسان تقویت می کند

Wortmannin potentiates the combined effect of etoposide and cisplatin in human glioma cells

Keywords: ATM; ataxia telangiectasia-mutated kinase; ATR; ataxia telangiectasia and Rad3-related kinase; CI; combination index; CLL; chronic lymphocytic leukemic cells; DNA-PK; DNA-dependent protein kinase; DNA-PKcs; DNA-dependent protein kinase catalytic subunit;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

اکسید نیتروس نقش دوگانه ای در آسیب اکسیداتیو میکروگلایی موش های کشت شده دارد، اما نه آستروگلیا

Nitric oxide plays a dual role in the oxidative injury of cultured rat microglia but not astroglia

Keywords: CNS; central nervous system; DAPI; 4,6-diamidin-2-phenylindol; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; DSBs; double strand breaks; EDTA; ethylenediaminetetraacetic acid; eNOS; endothelial NOS; ERK; extracellular-signal-regu

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

تشخیص کانون γH2AX در مغز نرمال موش و تومور مغزی پس از گرفتن درمان بور نوترون

Detection of γH2AX foci in mouse normal brain and brain tumor after boron neutron capture therapy

Keywords: Boron neutron capture therapy; High LET radiation; DSBs; γH2AX foci

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

سینتیک تعمیر مختلف DSB های ناشی از میتومایسین C در لنفوسیت های محیطی نوجوانان چاق و نرمال

Different repair kinetic of DSBs induced by mitomycin C in peripheral lymphocytes of obese and normal weight adolescents

Keywords: γ-H2AX; DSBs; Peripheral lymphocytes; Obesity; HMGB1

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Impact of DNA polymerase ζ mutations on genotoxic thresholds of oxidative mutagens

Keywords: TLS; translesion DNA synthesis; Pol; DNA polymerase; KBrO3; potassium bromate; Na2Cr2O7; sodium dichromate; 8-oxo-dG; 7,8-dihydro-8-oxo-2′-deoxyguanosine; D2781N; a human cell line that expresses a variant form of Pol ζ having asparagine instead of asp

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2018 سفارش ترجمه

Synthesis and biological evaluation of 4β-(thiazol-2-yl)amino-4′-O-demethyl-4-deoxypodophyllotoxins as topoisomerase-II inhibitors

Keywords: Podophyllotoxin; Topo-II inhibitors; DSBs; Cell cycle arrest;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2018 سفارش ترجمه

The functional roles of PML nuclear bodies in genome maintenance

Keywords: PML-NB; promyelocytic leukemia nuclear body; DSBs; DNA double-strand breaks; HR; homologous recombination; APL; acute promyelocytic leukemia; ALT; alternative lengthening of telomere; APB; ALT-associated PML bodies; PML nuclear body; SUMOylation; DNA repa

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Isoorientin triggers apoptosis of hepatoblastoma by inducing DNA double-strand breaks and suppressing homologous recombination repair

Keywords: Isoorientin; ATM; MRN complex; DSBs; HR;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

hMTH1 is required for maintaining migration and invasion potential of human thyroid cancer cells

Keywords: ATC; anaplastic thyroid cancer; BER; base excision repair; CREB; cAMP response element binding protein; DAPI; 4′,6-diamidine-2-phenylindole dihydrochloride; DDR; DNA damage response; dNTP; deoxynucleoside triphosphate; DSBs; double-stand breaks; DTC; di

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Beyond interstrand crosslinks repair: contribution of FANCD2 and other Fanconi Anemia proteins to the replication of DNA

Keywords: A-EJ; alternative end joing; APH; aphidicolin; BIR; break induced replication; BTRR; BLM helicase/topoisomerase IIIa (TOPOIIIa)/RMI1 and RMI2 cofactors; CFS; common fragile sites; Cis; cisplatin; DEB; diepoxybutane; DSBs; double strand breaks; DSEs; one e

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Targeting Long Noncoding RNA HMMR-AS1 Suppresses and Radiosensitizes Glioblastoma

Keywords: GBM; glioblastoma; HMMR; hyaluronan-mediated motility receptor; lncRNA; long noncoding RNA; HMMR-AS1; HMMR antisense RNA 1; DSBs; double-strand breaks; ATM; ataxia telangiectasia mutated kinase; HR; homologous repair;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Caspase-mediated cleavage of X-ray repair cross-complementing group 4 promotes apoptosis by enhancing nuclear translocation of caspase-activated DNase

Keywords: XRCC4; X-ray repair cross-complementing group 4; STS; staurosporine; CAD; caspase-activated DNase; ICAD; inhibitor of CAD; SRSF; serine/arginine-rich splicing factor; SRPK; SR protein kinase; Bcl; B-cell lymphoma; CLK; Cdc2-like kinase; Lig4; DNA ligase I

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Resveratrol represses estrogen-induced mammary carcinogenesis through NRF2-UGT1A8-estrogen metabolic axis activation

Keywords: 2-MeOE1/E2; 4-MeOE1/E2, methoxyestrogens; 2-OHE1/E2; 4-OHE1/E2, hydroxyestrogens; 53BP1; tumor protein p53 binding protein 1; DMBA; 7,12-dimethylbenz(a)anthracene; DSBs; DNA double-strand breaks; E1; estrone; E2; estradiol; E2-3G; E2-3-glucuronide; E2-17G

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Telomeric Recombination Induced by DNA Damage Results in Telomere Extension and Length Heterogeneity

Keywords: ALT; Alternative lengthening of telomeres; APBs; ALT-associated PML bodies; BIR; Break-induced replication; CO-FISH; Chromosome orientation fluorescence in situ hybridization; DDR; DNA damage response; DOX; Doxycycline; DSBs; Double-strand breaks; HR; Hom

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Breast cancer susceptibility protein 1 (BRCA1) rescues neurons from cerebral ischemia/reperfusion injury through NRF2-mediated antioxidant pathway

Keywords: ARE; antioxidative response element; AD; Alzheimer disease; ALS; amyotrophic lateral sclerosis; BRCA1; breast cancer susceptibility protein 1; BRCT; BRCA1 C-terminal; BER; base excision repair; CaMKII; calcium/calmodulin-dependent protein kinase II; CNS;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

A cardiac glycoside HTF-1 isolated from Helleborus thibetanus Franch displays potent in vitro anti-cancer activity via caspase-9, MAPK and PI3K-Akt-mTOR pathways

Keywords: Cardiac glycoside; Anti-Cancer; Helleborus thibetanus Franch.; Apoptosis; ERK and JNK pathways; PI3K-Akt-mTOR pathway; CGs; cardiac glycosides; FEN1; flap endonuclease 1; PARP; (poly (ADP-ribose) polymerase; MAPK; mitogen-activated protein kinase; ERK1/2;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

Two Weeks of Variable Stress Increases Gamma-H2AX Levels in the Mouse Bed Nucleus of the Stria Terminalis

Keywords: BNST; bed nucleus of the stria terminalis; DSBs; double-strand breaks; GSK3β; glycogen synthase kinase 3 β; MAPK; mitogen-activated protein kinase; mPFC; medial prefrontal cortex; PBS; phosphate-buffered saline; γH2AX; Histone H2A-X phosphorylated at s

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

Identification of rare heterozygous missense mutations in FANCA in esophageal atresia patients using next-generation sequencing

Keywords: EA; esophageal atresia; TEF; tracheoesophageal fistula; FANCA; Fanconi anemia complementation group A; AEG syndrome; anophthalmia-esophageal-genital syndrome; VACTERL syndrome; vertebral, anal, cardiac, tracheo-esophageal, renal, limb syndrome; CADD score

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

Chemical characterization and cytotoxic, genotoxic, and mutagenic properties of Baccharis trinervis (Lam, Persoon) from Colombia and Brazil

Keywords: CHO; Chinese Hamster Ovary; AE; Aqueous extracts; B; Brazil; C; Colombia; EAF; Ethyl Acetate Fraction; BF; Butanol Extract; ARF; Aqueous Residue Fraction; HPLC; High Performance Liquid Chromatography; HRMS; High Resolution Mass Spectrometry; MTT; 3-(4.5-d

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Uncharacterized ORF HUR1 influences the efficiency of non-homologous end-joining repair in Saccharomyces cerevisiae

Keywords: DDA; DNA damage array; DSBs; DNA double stranded breaks; GI; genetic interaction; HR; homologous recombination; HU; hydroxyurea; MMEJ; micro-homology mediated end joining; NHEJ; non-homologous end joining; PPI; protein-protein interaction; c-NHEJ; classic

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Tumor-promoting cyanotoxin microcystin-LR does not induce procarcinogenic events in adult human liver stem cells

Keywords: HL1-hT1; Microcystin-LR; Adult liver stem cells; Liver tumor-promotion; OATP; Multidrug resistance proteins; AB; Alamar Blue; AFP; α-fetoprotein; ALB; albumin; BCRP; breast cancer resistance protein; BSP; bromosulfophthalein; CFDA-AM; 5-carboxyfluorescei

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

ROS signalling in the biology of cancer

Keywords: AEJ; alternative end joining; ALL; acute lymphoblastic leukaemia; AML; acute myeloid leukaemia; Apaf-1; apoptotic protein activating factor 1; APL; acute promyelocytic leukaemia; ASK1; apoptosis signal regulating kinase 1; Bcr-Abl; breakpoint cluster-Abel

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

The FOXO3-FOXM1 axis: A key cancer drug target and a modulator of cancer drug resistance

Keywords: ABCB1; ATP-binding cassette sub-family B member 1; AML; acute myeloid leukaemia; AMPK; adenosine monophosphate-activated protein kinase; ATM; Ataxia-telangiectasia mutated; AURKA; aurora kinase A; BER; base excision repair; Bim; B-cell lymphoma 2 interact

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2018 سفارش ترجمه

Impact of obesity and overweight on DNA stability: Few facts and many hypotheses

Keywords: AGEs; advanced glycation end products; AP-1; activating protein -1; APE1; apurinic/apyrimidinic endonuclease 1; BER; base excision repair; BMI; body mass index; CAF; cafeteria diet; CAT; Catalase; CBMN-Cyt; cytokinesis block micronucleus cytome assay; CEL

دانلود رایگان متن کامل مقاله ISI 89 صفحه سال انتشار : 2018 سفارش ترجمه

Measurement of DNA damage in peripheral blood by the γ-H2AX assay as predictor of colorectal cancer risk

Keywords: DSBs; DNA double-strand breaks; PBLs; peripheral blood lymphocytes; CRC; colorectal cancer; IR; ionizing radiation; ORs; odds ratios; BMI; body mass index; HR; homologous recombination; NHEJ; non-homologous end joining; Gamma H2AX; Colorectal cancer risk;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Increasing genomic instability during cancer therapy in a patient with Li-Fraumeni syndrome

Keywords: CPC; choroid plexus carcinoma; DSBs; double-strands breaks; LFS; Li-Fraumeni syndrome; mFISH; multicolour fluorescence in-situ hybridization; NHEJ; non-homologous end-joining; SEM; scanning electron microscopy; TEM; transmission electron microscopy; γH2A

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

DNA damage, repair monitoring and epigenetic DNA methylation changes in seedlings of Chernobyl soybeans

Keywords: CNPP; Chernobyl nuclear power plant; IR; ionizing radiation; ROS; reactive oxygen species; SSBs; single strand breaks; DSBs; double strand breaks; R-C; radio-contaminated; DMSO; dimethyl sulfoxide; N/N; neutral unwinding/neutral electrophoresis; A/N; alka

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Multiple repair pathways mediate cellular tolerance to resveratrol-induced DNA damage

Keywords: HR; homologous recombination; TLS; translesion DNA synthesis; SSBR; single-strand break repair; BER; base excision repair; NER; nucleotide excision repair; NHEJ; non-homologous end joining; PPR; postreplication repair; DSBs; double- strand breaks; WT; wil

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Original ArticleThe depletion of ATM inhibits colon cancer proliferation and migration via B56γ2-mediated Chk1/p53/CD44 cascades

Keywords: ATM; Colon cancer; B56γ2; CD44; Tumorigenic potential; ATM; Ataxia-telangiectasia mutated; PIKK; phosphatidylinositol-3 kinase related kinase; FAT; FRAP-ATM-TRRAP domain; FATC; FAT-C-terminal domain; DDR; DNA damage response; DSBs; double strand breaks;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Interaction of Quindoline derivative with telomeric repeat-containing RNA induces telomeric DNA-damage response in cancer cells through inhibition of telomeric repeat factor 2

Keywords: ALT; alternative lengthening of telomeres; ATM; ataxia telangiectasia mutated; CD; circular dichroism; ChIP; chromatin immunoprecipitation; DAPI; 4′,6-diamidino-2-phenylindole; DDR; DNA damage response; DMSO; dimethyl sulfoxide; DSBs; DNA double-strand

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Original ArticleHDAC4 and HDAC6 sustain DNA double strand break repair and stem-like phenotype by promoting radioresistance in glioblastoma cells

Keywords: HDAC4; HDAC6; Glioblastoma; Radiotherapy; Radioresistance; GBM; glioblastoma; TMZ; temozolomide; RT; radiotherapy; HDACs; Histone deacetylases; HATs; Histone acetyltransferases; DSBs; DNA double-strand breaks; OS; Overall survival; shRNA; short hairpin RN

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

ReviewTranscription and DNA Damage: Holding Hands or Crossing Swords?

Keywords: DSBs; DNA double-strand breaks; DDR; DNA damage response; MRN; MRE11-RAD50-NBS1; ATM; ataxia telangiectasia mutated; MDC1; mediator of DNA-damage checkpoint; 53BP1; p53-binding protein; NHEJ; non-homologous end joining; ncRNA; non-coding RNA; HR; homo

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Fragile sites, dysfunctional telomere and chromosome fusions: What is 5S rDNA role?

Keywords: 5S rDNA; 5S ribosomal DNA; 5S rRNA; 5S ribosomal RNA; a; acrocentric; DSBs; double strand breaks; FISH; fluorescence in situ hybridization; ITS; interstitial telomeric sites; LINE; long interspaced nuclear element; LTR; long terminal repeat; m; metacentri

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2017 سفارش ترجمه

Valproic acid sensitizes breast cancer cells to hydroxyurea through inhibiting RPA2 hyperphosphorylation-mediated DNA repair pathway

Keywords: VPA; valproic acid; HU; hydroxyurea; IR; ionizing radiation; DSBs; double-strand breaks; HR; homologous recombination; RPA; replication protein A; RPA2-p; hyperphosphorylation of RPA2; wtRPA2; wild-type RPA2; muRPA2; hyperphosphorylation mutant RPA2; HDAC

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

Experimental evidence of oxidative stress in patients with l-2-hydroxyglutaric aciduria and that l-carnitine attenuates in vitro DNA damage caused by d-2-hydroxyglutaric and l-2-hydroxyglutaric acids

Keywords: L-2-HGA; l-2-hydroxyglutaric aciduria; L-2-HG; l-2-hydroxyglutaric acid; D-2-HGA; d-2-hydroxyglutaric aciduria; D-2-HG; d-2-hydroxyglutaric acid; 2-HG; 2-hydroxyglutaric acid; LC; l-carnitine; L2HGDH; l-2-hydroxyglutarate dehydrogenase gene; D2HGDH; d-2-h

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

The roles of subcellularly located EGFR in autophagy

Keywords: AMPK; AMP-activated protein kinase; ATG; autophagy-related; BCL2; B-cell lymphoma 2; BCL2L1; BCL2 like 1; BNIP3; BCL2/Adenovirus E1B-binding protein Nip3; CME; clathrin-mediated endocytosis; cytoSTAT3; cytoplasmic STAT3; Dsbs; double strand breaks; ECD; e

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2017 سفارش ترجمه

Trichodermin induces c-Jun N-terminal kinase-dependent apoptosis caused by mitotic arrest and DNA damage in human p53-mutated pancreatic cancer cells and xenografts

Keywords: Pancreatic cancer; Mitotic arrest; DNA damage; Apoptosis; c-Jun N-terminal kinase; Trichodermin; Bcl-2; B-cell lymphoma 2; Bcl-xL; B-cell lymphoma extra long; CDK; cyclin-dependent kinase; Cdc; cell division cycle; DSBs; double-strand breaks; DUSP1; dual

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2017 سفارش ترجمه