Keywords: Dusper; Protein phosphatase; Tumor suppressor; Phosphatase reactivation therapy; Synthetic lethality; Predictive marker; Prognostic marker; PP2A; PPM; ILKAP; PDP; PHLPP; PTPR; PTPN; DUSP; ACPP;
مقالات ISI Dusper (ترجمه نشده)
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Keywords: Dusper; 5mC; 5-methylcytosine; αKG; α-ketoglutarate; BMP4; bone morphogenetic protein 4; Dnmt; DNA methyltransferase; Dusp; dual-specific phosphatase; E; embryonic day; EpiLC; epiblast-like cell; EpiSC; epiblast stem cell; ESC; embryonic stem cell; FCS; fetal c
Keywords: Dusper; ALK; anaplastic lymphoma kinase; ALL; acute lymphoblastic leukemia; CLL; chronic lymphocytic leukemia; CML; chronic myelogenous leukemia; CNS; central nervous system; CRC; colorectal cancer; DTC; differentiated thyroid carcinoma; DUSP; dual specificity ph
Keywords: Dusper; Stem/progenitor cells; Sp1; P2X7 receptors; P2Y13 receptors; GSK3; Nrf-2; DUSP; MAPK signaling; (AIS); axon initial segment; (ATF3); activating transcription factor 3; (BBG); Brilliant Blue G; (BDNF); brain-derived neurotrophic factor; (bFGF); basic fibro
Keywords: Dusper; AP-1; activator protein 1; Dusp; dual-specificity phosphatase; Egr1; early growth response protein 1; ERK; extracellular signal regulated kinase; F2-KO mice; flotillin-2 knockout mice; Flot-1; flotillin-1; Flot-2; flotillin-2; HB-EGF; Heparin Binding-EGF;
Keywords: Dusper; ATM; ataxia telangiectasia mutated; ATP; adenosine triphosphate; Chk2; checkpoint kinase 2; DNA-PKcs; DNA-dependent protein kinase catalytic subunit; DUSP; dual-specificity phosphatase; HIV; human immunodeficiency virus; IL; interleukin; MCP1; monocyte ch
ERK1/2 inhibitors: New weapons to inhibit the RAS-regulated RAF-MEK1/2-ERK1/2 pathway
Keywords: Dusper; Akt; oncogene in the transforming retrovirus, AKT8; AP-1; activator protein 1; ARAF; v-raf murine sarcoma 3611 viral oncogene homologue; ASK1; apoptosis signal-regulating kinase 1; BCL2; B-cell lymphoma 2; BCL-XL; B-cell lymphoma extra large; BRAF; v-raf
Original ArticleMathematical modelling unveils the essential role of cellular phosphatases in the inhibition of RAF-MEK-ERK signalling by sorafenib in hepatocellular carcinoma cells
Keywords: Dusper; Hepatocellular carcinoma; Sorafenib; RAF-MEK-ERK cascade; Protein phosphatases; Mathematical modelling; DUSP; Dual-specificity phosphatases; EGFR; Epidermal Growth Factor Receptor; ERK1/2; Extracellular signal-Regulated Kinase 1/2; HCC; hepatocellular car
Mitogen-activated protein kinase phosphatase 1 (MKP-1) in macrophage biology and cardiovascular disease. A redox-regulated master controller of monocyte function and macrophage phenotype
Keywords: Dusper; ANP; Atrial natriuretic peptide; ARE; AU-rich elements; CS; catalytic sequence; DUSP; dual-specificity phosphatases; ERK; extracellular signal-regulated kinase; Grx; glutaredoxin; HA; hyaluronic acid; IFN; Interferon; IL; Interleukin; JNK; c-Jun N-termina
OH1 from Orf Virus: A New Tyrosine Phosphatase that Displays Distinct Structural Features and Triple Substrate Specificity
Keywords: Dusper; crystallography; Orf virus; tyrosine phosphatase; phosphatidylinositol; ORFV; Orf virus; DUSP; dual-specificity phosphatase; PTPs; protein tyrosine phosphatases; P-loop; phosphate-binding loop; PtdIns; phosphoinositides; SEC; size exclusion chromatography
Identification of sennoside A as a novel inhibitor of the slingshot (SSH) family proteins related to cancer metastasis
Keywords: Dusper; PTPs; protein tyrosine phosphatases; PTKs; protein tyrosine kinases; DUSP; dual specificity phosphatase; ADF; actin-depolymerizing factor; IPTG; isopropyl-β-d-thiogalactoside; DiFMUP; 6,8-difluoro-4-methylumbelliferyl phosphate; MBP; maltose binding prot
Modulation of VEGF receptor 2 signaling by protein phosphatases
Keywords: Dusper; AMD; age-related macular degeneration; BrdU; bromodeoxyuridine; Cys; cysteine; DR; diabetic retinopathy; DUSP; dual specificity phosphatase; E; embryonic day; EC; endothelial cells; ECM; extracellular matrix; ER; endoplasmic reticulum; HUVEC; human umbili
Modulation of dendritic cell and T cell cross-talk during aging: The potential role of checkpoint inhibitory molecules
Keywords: Dusper; APC; antigen-presenting cell; cDC; conventional dendritic cell; CTLA-4; cytotoxic T lymphocyte antigen-4; DC; dendritic cell; DUSP; dual-specific phosphatase; GAL-9; galectin-9; ICOS; inducible T cell co-stimulator; ICOSL; inducible T cell co-stimulator l
Regulation of cardiac hypertrophy and remodeling through the dual-specificity MAPK phosphatases (DUSPs)
Keywords: Dusper; DUSP; dual-specificity phosphatase; ERK; extracellular signal-regulated kinase; I/R; ischemia reperfusion; JNK; c-Jun N-terminal kinase; KO; knockout; MAPK; mitogen-activated protein kinase; MAPKKs; MAPK kinases; MKPs; MAPK phosphatases; TAC; transverse a
Long Noncoding RNA PICSAR Promotes Growth of Cutaneous Squamous Cell Carcinoma by Regulating ERK1/2 Activity
Keywords: Dusper; AK; actinic keratosis; cSCC; cutaneous squamous cell carcinoma; cSCCIS; cSCC in situ; DUSP; dual-specificity phosphatase; ERK; extracellular signal-regulated kinase; FC; fold change; lncRNA; long noncoding RNA; JNK; c-Jun N-terminal kinase; MAPK; mitogen-
Genomics of human fatty liver disease reveal mechanistically linked lipid droplet-associated gene regulations in bland steatosis and nonalcoholic steatohepatitis
Keywords: Dusper; ACACB; acetyl-CoA carboxylase beta acetyl-CoA carboxylase beta; ACAT1; acetyl-CoA acetyltransferase 1; ACLY; ATP citrate lyase; AMPK; 5â²AMP-activated protein kinase; ASCL1; acyl-CoA synthetase long-chain family member 1; ACSL4; acyl CoA synthetases long
Emerging role of protein phosphatases changes the landscape of phospho-signaling in DNA damage response
Keywords: Dusper; 53BP1; p53 binding protein 1; ATM; ataxia-telangiectasia mutated; ATR; ataxia telangiectasia and Rad3 related; BLM; blooms syndrome RecQ helicase-like, human homolog of SGS1; BRCA1; breast cancer 1, early onset; CDC; cell division cycle; CDK; cyclin depen
Neuroprotection Mediated by P2Y13 Nucleotide Receptors in Neurons
Keywords: Dusper; P2Y13 receptor; Nucleotide receptors; ERK1/2 signaling; GSK3 signaling; MAPK protein phosphatases; DUSP; Neuroprotection
The Nuclear Factor κB pathway: A link to the immune system in the radiation response
Keywords: Dusper; Nuclear Factor κB; Immune system; Cellular radiation response; Linear energy transfer; Bystander effect; Chemokines; A20 (TNFAIP3); tumor necrosis factor inducible protein 3; ARD; ankyrin repeat domain; ATM; ataxia telangiectasia mutated protein; β-TrCP
Neuroprotection elicited by P2Y13 receptors against genotoxic stress by inducing DUSP2 expression and MAPK signaling recovery
Keywords: Dusper; CaMKII; calcium/calmodulin kinase II; CREB; (cAMP-response-element-binding protein)-binding protein; DAPI; 2-(4-amidinophenyl)-1H-indole-6-carboxamidine; DUSP; dual-specificity phosphatase; ERK; extracellular-signal-regulated kinase; JNK; c-Jun Kinase; 2M
Determinants of the tumor suppressor INPP4B protein and lipid phosphatase activities
Keywords: Dusper; PI3K; by phosphatidyl 3-kinase; PI4K; phosphatidyl 4-kinase; PI5K; phosphatidyl 5-kinase; INPP4B; inositol polyphosphate 4-phosphatase type II; PTP; protein tyrosine phosphatase; pNPP; para-nitrophenyl phosphate; DifMUP; 6,8-difluoro-4-methylumbelliferyl
Mechanism of Siglec-8-mediated cell death in IL-5-activated eosinophils: Role for reactive oxygen species-enhanced MEK/ERK activation
Keywords: Dusper; Eosinophils; cell death; signaling; 7AAD; 7-Aminoactinomycin D; DPI; Diphenyleneiodonium; DUSP; Dual-specificity phosphatase; EPX; Eosinophil peroxidase; ERK; Extracellular signal-regulated kinase; H2O2; Hydrogen peroxide; HRP; Horseradish peroxidase; JNK
p38 mitogen-activated protein kinase (p38 MAPK)-mediated autoimmunity: Lessons to learn from ANCA vasculitis and pemphigus vulgaris
Keywords: Dusper; AIH; autoimmune hepatitis; ANCA; anti-neutrophil cytoplasmic antibody; DSG; desmoglein; DUSP; dual specificity phosphatase; EAE; experimental autoimmune encephalomyelitis; GADD45; growth arrest and DNA damage inducible gene 45; GC; germinal center; HSP; h
The genetic association of DUSP6 with bipolar disorder and its effect on ERK activity
Keywords: Dusper; BD; bipolar disorder; COMT; catechol-O-methyltransferase; DIGS; Diagnostic Interview for Genetic Studies; DISC1; disrupted in schizophrenia 1; DMEM; Dulbecco's modified Eagle's medium; DNA; deoxyribonucleic acid; DUSP; dual-specificity phosphatase; ERK; e
Prohibitin-1 deficiency promotes inflammation and increases sensitivity to liver injury
Keywords: Dusper; Phb; prohibitin; MCDD; methionine and choline deficient diet; LPS; bacterial lipopolysaccharide; PP2A; protein phosphatase 2 A; GSK; glycogen synthase kinase; ETF; electron transfer flavoportein; ADH; aldehyde dehydrogenase; AMPK; AMP kinase; IPA; Ingenui
Phosphorylation of the M3/6 dual-specificity phosphatase enhances the activation of JNK by arsenite
Keywords: Dusper; JNK; c-Jun N-terminal kinase; DUSP; dual-specificity phosphatase; JIP; JNK-interacting protein; MAPK; mitogen-activated protein kinase; MKP; MAP kinase phosphatase; SAPK; stress-activated protein kinase; M3/6; DUSP8; JNK; MKP; Protein phosphorylation; Ars
Invited reviewERK1/2 MAP kinases: Structure, function, and regulation
Keywords: Dusper; C-spine; catalytic spine; CK; casein kinase; cPLA2; cytosolic phospholipase A2; CRM1; chromosome region maintenance 1; CTKD; C-terminal kinase domain; DRS; D-site recruitment site; DUSP; dual-specificity phosphatase; EGFR; epidermal growth factor receptor
Structural variability of the ubiquitin specific protease DUSP-UBL double domains
Keywords: Dusper; Ubiquitin specific protease; DUSP; UBL; X-ray;
The dual-specificity protein phosphatase MkpB, homologous to mammalian MKP phosphatases, is required for D. discoideum post-aggregative development and cisplatin response
Keywords: Dusper; MKP phosphatase; DUSP; Dictyostelium; Development; Cisplatin; Protein phosphatase
Attenuation of the acute inflammatory response by dual specificity phosphatase 1 by inhibition of p38 MAP kinase
Keywords: Dusper; BMMs; bone marrow-derived macrophages; COX2; cyclooxygenase-2; DUSP; dual specificity phosphatase; ERK; extracellular-signal-regulated-kinase; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GM-CSF; granulocyte/macrophage-colony stimulating factor; IFNγ
Differential regulation of MAP kinase activation by a novel splice variant of human MAP kinase phosphatase-2
Keywords: Dusper; MAP kinase phosphatase; MAP kinase; JNK; ERK; MKP-2; DUSP4; MKP; DUSP; Tyrosine kinase;
Pharmacodynamic Characterization of the Efficacy Signals Due to Selective BRAF Inhibition with PLX4032 in Malignant Melanoma
Keywords: Dusper; AKT; v-akt murine thymoma viral oncogene homolog; ANOVA; analysis of variance; ATCC; American Type Culture Collection; BRAF; v-raf murine sarcoma viral oncogene homolog B1; BRAFm; BRAF mutation; CKIT; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene
NSC-87877, inhibitor of SHP-1/2 PTPs, inhibits dual-specificity phosphatase 26 (DUSP26)
Keywords: Dusper; PTP; protein tyrosine phosphatase; DUSP; dual-specificity protein phosphatase; NSC-87877; 8-hydroxy-7-(6-sulfonaphthalen-2-yl)diazenyl-quinoline-5-sulfonic acid; MAPK; mitogen-activated protein kinase; DUSP26; NSC-87877; Protein tyrosine phosphatase (PTP)
Molecular identification and functional characterization of a Drosophila dual-specificity phosphatase DMKP-4 which is involved in PGN-induced activation of the JNK pathway
Keywords: Dusper; DUSP; dual-specificity phosphatase; DSP domain; dual-specificity phosphatase domain; pNPP; p-nitrophenyl phosphate; MAPK phosphatases (MKPs); DMKP-4; MAP (Mitogen-activated protein) kinases; DJNK;
The remote ischemic preconditioning stimulus modifies gene expression in mouse myocardium
Keywords: Dusper; CNBP; cellular nucleic acid-binding protein; CPB; cardiopulmonary bypass; DUSP; dual-specificity phosphatase; FABP; fatty acid-binding protein; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; HADHSC; l-3-hydroxyacyl-CoA dehydrogenase; HSP; heat shock
Conditional expression of MAP kinase phosphatase-2 protects against genotoxic stress-induced apoptosis by binding and selective dephosphorylation of nuclear activated c-jun N-terminal kinase
Keywords: Dusper; BSA; bovine serum albumin; CI; catalytically inactive; cisplatin; cis-Platinum (II) Diammine Dichloride; Dox; doxycyclin; DAPI; 4â²,6â²-diamidino-2-phenylindole hydrochloride; DUSP; dual specificity phosphatase; ECL; enhanced chemoluminescence; ERK; ext