Keywords: Collagen VIII; Cancer; COPD; Angiogenesis; Biomarker; ECM; Antibody; Antigen
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Keywords: Fuel price elasticity; Diesel; Gasoline; Climate policy; Air pollution; Dynamic panel; H23; R48; Q41; Q48; Q53; Q54; AB; Arellano-Bond; ADL; autoregressive distributed lag; CO2; carbon dioxide; EC; European Commission; ECM; error correction model; ESD; ef
Keywords: ASP+; 4-(4-(dimethylamino)styryl)-N-methylpyridinium iodide; BAK; bioartificial kidney device; BSA; bovine serum albumin; ciPTEC; conditionally immortalized human proximal tubule epithelial cells; CWF; clean water flux; ECM; extracellular matrix; HBSS; Ha
Keywords: Resveratrol; Resveratrol metabolites; Epithelial-mesenchymal transition; Cancer metastasis; EMT; epithelial-mesenchymal transition (EMT); TGF; transforming growth factor; ECM; extracellular matrix; MET; mesenchymal-epithelial transition; EGF; epidermal gr
No difference in ectomycorrhizal morphotype composition between abandoned and inhabited nests of wood ants (Formica polyctena) in a central European spruce forest
Keywords: Nutrient-rich hotspots; EcM; Root biomass; Moisture; Ergosterol; Available nutrients;
Laminin peptide YIGSR enhances epidermal development of skin equivalents
Keywords: Collagen; Laminin; Peptide YIGSR; Proliferation; Skin equivalents; BM; basement membrane; DE; dermal equivalent; ECM; extracellular matrix; PCNA; proliferating cell nuclear antigen; SE; skin equivalent;
The role of SIRT1 in diabetic retinopathy
Keywords: SIR2; Silent Information Regulator2; HDACs; histone deacetylaser; NAD+; nicotinamide adenine dinucleotide; DM; diabetes mellitus); AGEs; advanced glycation end products; AMPK; adenosine monophosphate-activated protein kinas; TGFβ1; transforming growth fa
Percutaneous ablative cryoimmunotherapy for micrometastaic abscopal effect: No complications
Keywords: Abscopal effect; Cancer stem cell; Checkpoint inhibitor; Cryoimmunotherapy; Neoantigen; Renal cell carcinoma; Tumor microenvironment; Tumor vaccine; PD-1; programmed death 1; TIL; tumor-infiltrating lymphocytes; ECM; extracellular matrix; TAA; tumor-assoc
Keratinocytes negatively regulate the N-cadherin levels of melanoma cells via contact-mediated calcium regulation
Keywords: Melanoma; Melanocyte; Keratinocyte; N-cadherin; Cell-cell interaction; TRPC; transient receptor potential cation channel; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; ECM; extracellular matrix;
TUG1 is involved in liver fibrosis and activation of HSCs by regulating miR-29b
Keywords: Liver fibrosis; HSCs; ECM; lncRNA-TUG1; ceRNA;
Biomimetic scaffold containing PVDF nanofibers with sustained TGF-β release in combination with AT-MSCs for bladder tissue engineering
Keywords: SMC; smooth muscle cell; PVDF; poly (vinylidene fluoride); AT-MSCs; adipose tissue derived mesenchymal stem cells; TCPS; tissue culture polystyrene; ECM; extracellular matrix; TGF-β; transforming growth factor beta-1; SEM; scanning electron microscopy; H
Circular RNA Atp9b, a competing endogenous RNA, regulates the progression of osteoarthritis by targeting miR-138-5p
Keywords: OA; osteoarthritis; circRNAs; circular RNAs; ceRNAs; competing endogenous RNAs; miRNAs; microRNAs; IL-1β; interleukin-1β; ECM; extracellular matrix; GO; gene ontology; KEGG; Kyoto Encyclopedia of Genes and Genomes; qRT-PCR; quantitative real-time polyme
Development of a demineralized and decellularized human epiphyseal bone scaffold for tissue engineering: A histological study
Keywords: ECM; extracellular matrixes; RABMC; rat adherent bone marrow cells; SDS; sodium dodecyl sulfate; DAPI; DNA using 4â²,6-diamidino-2-phenylindole; DMEM; Dulbecco's Modified Eagle's Medium; FBS; fetal bovine serum; Extracellular matrix; Human epiphyseal
Novel approaches in the treatment of diabetic cardiomyopathy
Keywords: ACE; angiotensin convertase enzyme; ACEi; angiotensin convertase enzyme inhibitor; ADP; adenosine di phosphate; AGE; advanced glycation end products; AM; adrenomedullin; AMP; adenosine mono phosphate; ARB; angiotensin receptor blocker; ATP; adenosine tri
Synthetic analogues of the parasitic worm product ES-62 reduce disease development in in vivo models of lung fibrosis
Keywords: ECM; extracellular matrix; PC; phosphorylcholine; SMA; small molecule analogue; Drug development; Fibrosis; ES-62; Immunomodulation; Parasitic worm;
MicroRNA co-expression patterns unravel the relevance of extra cellular matrix and immunity in breast cancer
Keywords: Breast cancer; miRNA; miRNA cluster; miRNA co-expression; Microarray; BC; breast cancer; DCIS; ductal carcinoma in-situ; ECM; extracellular matrix; EMT; epithelial to mesenchymal transition; ER; estrogen receptor; GSEA; gene set enrichment analysis; IDC;
Molecularly targeted anti-cancer drugs inhibit the invasion and metastasis of hepatocellular carcinoma by regulating the expression of MMP and TIMP gene families
Keywords: Hepatocellular carcinoma; Sorafenib; Regorafenib; Levnatinib; Invasion; Metastasis; Hepatocellular carcinoma; HCC; Matrix metalloproteinases; MMPs; Tissue inhibitors of MMPs; TIMPs; Extracellular matrix; ECM; Receptor tyrosine kinases; RTKs; Vascular endo
Evidence for the coupling of extraradical mycorrhizal hyphae production to plant C assimilation in Japanese warm-temperate forest of arbuscular mycorrhizal and ectomycorrhizal tree species
Keywords: Arbuscular mycorrhiza; Extraradical mycorrhizal hyphae; Hyphal carbon mass; Hyphal in-growth mesh bag; Hyphal length; Plant-Soil carbon flux; AM; arbuscular mycorrhizal; ECM; ectomycorrhizal; EMH; extraradical mycorrhizal hyphae; HC; hyphal carbon mass; H
Reprint of: A three-dimensional in vitro HepG2 cells liver spheroid model for genotoxicity studies
Keywords: 2D; two-dimensional; 3D; three-dimensional; AhR; aryl hydrocarbon receptor; B[a]P; benzo[a]pyrene; BCG; bromocresol green; CBMN; cytokinesis-blocked micronucleus; CBPI; cytokinesis-block proliferation index; CYP; cytochrome P450; DMSO; dimethyl sulfoxide;
MicroRNA-21a-5p promotes fibrosis in spinal fibroblasts after mechanical trauma
Keywords: SCI; spinal cord injury; miRNA; microRNA; SD; scratch damage; ECM; extracellular matrix; CNS; central nervous system; FN; fibronectin; Col1a1; type I a1collagen; Col1a2; type I a2 collagen; Col IV; type IV collagen; qRT-PCR; quantitative real-time PCR; GA
Respective optimal calcium concentrations for proliferation on type I collagen fibrils in two keratinocyte line cells, HaCaT and FEPE1L-8
Keywords: Type I collagen gel; Keratinocyte proliferation; Calcium concentration; DAG; diacylglycerol; DMEM; Dulbecco's Modified Eagle's Medium; DMEM (0); DMEM supplemented without fetal bovine serum; DMEM (10); DMEM supplemented with 10% fetal bovine serum; ECM; e
MicroRNA 148a-3p promotes Thrombospondin-4 expression and enhances angiogenesis during tendinopathy development by inhibiting Krüppel-like factor 6
Keywords: Tendinopathy; Angiogenesis; miR-148a-3p; Thrombospondin-4 (Tsp-4); Krüppel-like factor 6 (KLF6); PRP; platelet-rich plasma; Tsp-4; thrombospondin-4; ECM; extracellular matrix; miRs; microRNAs; KLF6; Krüppel-like factor 6;
Extracellular matrix protein production in human adipose-derived mesenchymal stem cells on three-dimensional polycaprolactone (PCL) scaffolds responds to GDF5 or FGF2
Keywords: 3D; three-dimensional; ACL; anterior cruciate ligament; MSC; mesenchymal stem/stromal cells; calcein AM; calcein acetoxymethyl; ECM; extracellular matrix; EthD-1; ethidium homodimer; FGF2; fibroblast growth factor 2 (basic); GDF5; growth and differentiati
The role of TRPV4 in fibrosis
Keywords: α-SMA; α-smooth muscle actin; aa; amino acids; AHF; alcohol/high fat diet; AIP4; atrophin-interacting protein 4; ANK; ankyrin; ARS-L; arachidonate-like recognition sequence; ASL; airway surface liquid; BKCa; Ca2 +-dependent K+; [Ca2 +]i; intracellular
Xanthine oxidase is hyper-active in Duchenne muscular dystrophy
Keywords: 6MWT; six minute walk test; BMD; Becker muscular dystrophy; DMD; Duchenne muscular dystrophy; ECM; extracellular matrix; EDL; extensor digitorum longus; HPLC; high performance liquid chromatography; mdx; DMD mouse model; ROS; reactive nitrogen species; Sc
Anti-fibrotic effect of paramylon nanofibers from the WZSL mutant of Euglena gracilis on liver damage induced by CCl4 in mice
Keywords: AST; aspartate aminotransferase; CAT; catalase; ECM; extracellular matrix; EDV; end-diastolic velocity; GPx; glutathione peroxidase; hf-US; high frequency-ultrasound, HSC, hepatic stellate cells; L/K; liver/kidney ratio; MV; mean velocity; PAMPs; pathogen
Flavonoid-rich Scabiosa comosa inflorescence extract attenuates CCl4-induced hepatic fibrosis by modulating TGF-β-induced Smad3 phosphorylation
Keywords: TF-SC; total flavonoids of scabiosa comosa inflorescences; TGF-β1; transforming growth factor-β1; HSCs; hepatic stellate cells; TβRI; TGF-β type I receptor; TβRII; TGF-β type II receptor; ECM; extracellular matrix; α-SMA; alpha-smooth muscle actin;
Discovery of 1-(4-((3-(4-methylpiperazin-1-yl)propyl)amino)benzyl)-5-(trifluoromethyl)pyridin-2(1H)-one, an orally active multi-target agent for the treatment of diabetic nephropathy
Keywords: ACR; albumin-to-creatinine ratio; AUC0-t; area under the curve; BuOH; n-butanol; BUN; blood urea nitrogen; Cmax; peak concentration; C13-NMR; C13-nuclear magnetic resonance; CCr; creatinine clearance rate; CCR2; CCchemkin receptor 2; CDCl3; Deuterotrichlo
Role of the Crumbs proteins in ciliogenesis, cell migration and actin organization
Keywords: AJ; adherens junction; TJ; tight junction; aPKC; atypical protein kinase C; CRB; crumbs; DLG; discs large; ECM; extracellular matrix; FERM; 4.1 ezrin radixin moesin; LGL; lethal giant larvae; MAGUK; membrane-associated guanylate kinase; MUPP1; multi PDZ d
A three-dimensional in vitro HepG2 cells liver spheroid model for genotoxicity studies
Keywords: 2D; two-dimensional; 3D; three-dimensional; AhR; aryl hydrocarbon receptor; B[a]P; benzo[a]pyrene; BCG; bromocresol green; CBMN; cytokinesis-blocked micronucleus; CBPI; cytokinesis-block proliferation index; CYP; cytochrome P450; DMSO; dimethyl sulfoxide;
The physiopathologic interplay between stem cells and tissue niche in muscle regeneration and the role of IL-6 on muscle homeostasis and diseases
Keywords: IL-; interleukin; SC; satellite cell; ECM; extracellular matrix; MuSCs; muscle stem cells; ROS; reactive oxygen species; Treg; regulatory T cells; Pax7; Paired box protein 7; Myf5; myogenic factor 5; MyoD; myoblast determination protein; MRF; muscle regul
FRA1 mediates the activation of keratinocytes: Implications for the development of psoriatic plaques
Keywords: EMT; epithelial-mesenchymal transition; RNAseq; next generation sequencing of the transcriptome; ECM; extracellular matrix; qPCR; quantitative polymerase chain reaction; FDR; false discovery rate; FRA1; Keratinocytes; EMT; Inflammation; Psoriasis; Wound
Biglycan gene connects metabolic dysfunction with brain disorder
Keywords: AUC; area under the curve; CREB; cAMP response element binding protein; BDNF; brain-derived neurotrophic factor; ECM; extracellular matrix; HDL; high-density lipoprotein; IPGTT; intraperitoneal glucose tolerance test; NTC; non-target control; ORO; Oil Red
Cathepsin B inhibitors: Further exploration of the nitroxoline core
Keywords: Abz; 2-aminobenzoyl; AMC; 7-amido-4-methylcoumarin; catB; cathepsin B; DIPEA; N,N-diisopropylethylamine; DMSO; dimethyl sulfoxide; ECM; extracellular matrix; EDC; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide; HATU; 1-[bis(dimethylamino)methylene]-1H-1,2,
MicroRNAs as biological regulators in skin disorders
Keywords: ds; double stranded; ECM; extracellular collagen matrix; FGF; fibroblast growth factor; HS; hypertrophic scaring; HSFBs; hypertrophic scaring affected fibroblasts; miR; microRNA; PCR; polymerase chain reaction; PDGF; platelet-derived growth factor; PremiR
Electronegative LDL induces MMP-9 and TIMP-1 release in monocytes through CD14 activation: Inhibitory effect of glycosaminoglycan sulodexide
Keywords: ECM; extracellular matrix; GAG; glycosaminoglycan; IL; Interleukin; LDL; low density lipoprotein; LPS; lipopolysaccharide; LSU; lipasemic unit; MMP; matrix metalloproteinase; SDX; sulodexide; TIMP; tissue inhibitor of metalloproteinase; TLR; toll-like rec
miR-23c suppresses tumor growth of human hepatocellular carcinoma by attenuating ERBB2IP
Keywords: HCC; hepatocellular carcinoma; TACE; transarterial chemoembolization; miRNA; microRNAs; LIHC; liver hepatocellular carcinoma; ELAVL1; ELAV like RNA binding protein 1; GSK3β; glycogen synthase kinase 3 beta; ECM; extracellular matrix; CRC; colorectal canc
Cathepsin D non-proteolytically induces proliferation and migration in human omental microvascular endothelial cells via activation of the ERK1/2 and PI3K/AKT pathways
Keywords: EOC; epithelial ovarian cancer; CathD; cathepsin D; EC; endothelial cell; ERK1/2; extracellular signal regulated kinase; AKT; protein kinase B; CAM; chorioallontoic membrane model; ECM; extracellular matrix; Cathepsin D; Non-proteolytic; Proliferation; Mi
Adiponectin inhibits hepatic stellate cell activation by targeting the PTEN/AKT pathway
Keywords: HSCs; hepatic stellate cell; TGFβ1; Transforming growth factor β1; PTEN; Phosphatase and tensin homolog deletion 10; DNMT; DNA methyltransferase; ECM; extracellular matrix; α-SMA; α-smooth muscle actin; CCl4; carbon tetrachloride; PTP1B; protein tyros
Hypoxia Inducible Factors Modify Collagen I Fibers in MDA-MB-231 Triple Negative Breast Cancer Xenografts
Keywords: Col1; Collagen I; DAB; 3,3â²-diaminobenzedine; DS; Double Silenced; ECM; Extracellular Matrix; HIF; Hypoxia Inducible Factor; H&E; Hematoxylin and eosin; LOX; Lysyl Oxidase; MMP; Matrix Metalloproteinase; MT-MMP; Membrane-Type Matrix Metalloproteinase; P
Increased fibrosis: A novel means by which GH influences white adipose tissue function
Keywords: GH; growth hormone; GHR; growth hormone receptor; GHRKO; growth hormone receptor knockout; FaGHRKO; fat growth hormone receptor knockout; LiGHRKO; liver growth hormone receptor knockout; IGF-1; insulin-like growth factor 1; WAT; white adipose tissue; ECM;
Transcriptional profiling of the ductus arteriosus: Comparison of rodent microarrays and human RNA sequencing
Keywords: Ao; aorta; DEG; differentially expressed gene; bioDBnet; biological Database network; BP; biological process; CC; cellular component; DAVID; database for annotation, visualization, and integrated discovery; ECM; extracellular matrix; FDR; false discovery
Taking the lead - how keratinocytes orchestrate skin T cell immunity
Keywords: CLA; Cutaneous leukocyte antigen; ECM; extracellular matrix; HF; shair follicles; ILC; sinnate lymphoid cells; IRF; sinterferon-regulatory factors; LCs; Langerhans cells; mTreg; memory Treg; NLRs; nucleotide-binding oligomerization domain(NOD)-like recept
A pathogenetic role for M1 macrophages in peritoneal dialysis-associated fibrosis
Keywords: PD; Peritoneal dialysis; PDFs; peritoneal dialysis fluids; PF; peritoneal fibrosis; LC; Liposomes clodronate; LV; Liposomes vehicle; ECM; extracellular matrix; EMT; epithelial-mesenchymal transition; TLR4; Toll-like receptor 4; α-SMA; alpha-smooth muscle
Schistosoma mansoni venom allergen-like protein 18 (SmVAL18) is a plasminogen-binding protein secreted during the early stages of mammalian-host infection
Keywords: SmVAL; Schistosoma mansoni venom allergen-like; SCP/TAPS; sperm coat protein/Tpx-1/Ag5/PR-1/Sc7; ECM; extracellular matrix; BM; basement membrane; PLG; plasminogen; uPA; urokinase-type plasminogen activator; Schistosomiasis; SCP/TAPS; SmVAL18; Plasminogen
Resveratrol inhibits proliferation, migration and invasion via Akt and ERK1/2 signaling pathways in renal cell carcinoma cells
Keywords: RES; resveratrol; RCC; renal cell carcinoma; EMT; epithelial-mesenchymal transition; MMP; matrix metalloproteinase; ECM; extracellular matrix; ERK; extracellular signal-regulated protein kinase; MAPK; mitogen-activated protein kinases; DMEM; Dulbecco's
Halofuginone attenuates intervertebral discs degeneration by suppressing collagen I production and inactivating TGFβ and NF-кB pathway
Keywords: IVD; intervertebral discs; ECM; extracellular matrix; TGFβ; transform growth factor-β; NF-κB; nuclear factor of kappa b; IL-1β; interleukin 1β; IL-6; interleukin 6; IL-8; interleukin 8; NP; nucleus pulpous; AF; annulus fibrosus; CEPs; cartilaginous e
Hyaluronan in experimental injured/inflamed cartilage: In vivo studies
Keywords: ACAN; aggrecan; ADAMTS-5; A disintegrin and metalloproteinase with thrombospondin motifs 5; A2AR; adenosine type 2 receptor; Bax; BCL2 associated X protein; Bcl-2; B-cell lymphoma 2; CD44; cluster determinant 44; Col2A; collagen type II alpha; Col1a1; col
Horizontal transfer of exosomal CXCR4 promotes murine hepatocarcinoma cell migration, invasion and lymphangiogenesis
Keywords: CXCR4; CXC chemokine recepter-4; SDF-1; stromal cell-derived factor-1; MMPs; matrix metalloproteinases; LECs; lymphatic endothelial cells; ECM; endothelial cell culture medium; TEM; Transmission electron microscopy; VEGF-C; Vascular endothelial growth fac
Maclurin exerts anti-cancer effects on PC3 human prostate cancer cells via activation of p38 and inhibitions of JNK, FAK, AKT, and c-Myc signaling pathways
Keywords: Small-cell neuroendocrine carcinomas; Reactive oxygen species; Maclurin; Metastasis; Matrix metalloproteinases; MAPK; SCNC; Small-cell neuroendocrine carcinoma; NSCLC; Non-small-cell lung cancer; ECM; Extracellular matrix; MMP; Matrix metalloproteinase; M