Keywords: ANOVA; analysis of variance; DA; dopamine; DAT; dopamine transporter; DOPAC; 3,4-dihydroxyphenylacetic acid; EDTA; ethylenediaminetetraacetic acid; EPM; Elevated Plus Maze; GAPDH; glyceraldahyde-3-phosphate-dehydrogenase; HPA; hypothalamus-pituitary-a
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Keywords: AMYG; amygdala; BLA; basolateral nucleus of the amygdala; CeA; central nucleus of the amygdala; CORT; corticosterone; DIG; digoxigenin; ENK; enkephalin; EPM; elevated plus maze; FISH; fluorescence in situ hybridization; GABA; γ-aminobutyric acid; HYPO; h
Keywords: Sarcocystis; Neospora; Opossum; Protozoa; EPM; Central nervous system;
Keywords: ACC; anterior cingulate cortex; ALB; anxiety-like behavior; BDNF; brain-derived neurotrophic factor; BLA; basolateral nuclei of amygdala; BrDU; bromodeoxyuridine; BV; bee venom; CCI; chronic constriction injury; CeA; central nuclei of amygdala; CeLC; late
Keywords: EPM; elevated plus maze; Anxiolytic-like activity; Dipeptide; Aromatic amino acid; Tyrosyl leucine; Structure-activity relationship;
Keywords: CLA; conjugated linoleic acid; EPM; elevated plus maze; GMF; goat milk fat; C; control; G; gestation; L; lactation; G + L; gestation + lactation; Anxiety; Conjugated linoleic acid; Elevated plus maze; Neurodevelopment; Physical parameters; Somatic mat
Keywords: AA; Alko alcohol; ANA; Alko non-alcohol; CPP; Conditioned-Place Preference; EPM; Elevated plus maze; EtOH; Ethanol; HAD; High Alcohol Drinking; HAM; High Anxiety Mice; LAD; Low Alcohol Drinking; LAM; Low Anxiety Mice; MBT; Marble burying test; sNP; Sardin
Keywords: ASR; acoustic startle reflex; BW; body weight; EMT; light/dark emergence test; EPM; elevated plus maze; ITI; intertrial interval; PPI; prepulse inhibition; SCM; sweetened condensed milk; SPL; sound pressure level; W[hsd]; HsdHan:WIST; W[Jan]; RjHan:WI; W[
Keywords: AFR; animal facility rearing; CeA; central nucleus of the amygdala; EPM; elevated plus maze; FST; forced swimming test; HPA; hypothalamic-pituitary-adrenal; PB; phosphate buffer; PPD; postpartum day; Maternal separation; Maternal behavior; Anxiety; De
Keywords: BDZ; benzodiazepinic; BUSP; buspirone; CA; carvacryl acetate; DZP; diazepam; EPM; elevated plus-maze test; EL; epoxy-limonene; FLU; flumazenil; GABA; gamma-aminobutyric acid; LDB; light-dark box test; MBT; marble-burying test; NF; number of falls; NELB;
Keywords: LA; low-anxiety; HA; high-anxiety; IC; inferior colliculus; CIC; central nucleus of the inferior colliculus; AEP; auditory evoked potentials; GABA; γ-aminobutyric acid-A; EPM; elevated plus maze; BLA; basolateral amygdala complex; CEA; central nucleus of
Keywords: ANOVA; analysis of variance; bHR; bred high-responders; bLR; bred low-responders; CCK; cholecystokinin; Dig; digoxigenin; EPM; elevated plus-maze; FGF-R1; fibroblast growth factor receptor-1; FGF2; fibroblast growth factor-2 (basic fibroblast growth facto
Keywords: EE; environmental enrichment; EZM; elevated zero-maze; 4-RAWM; four-arm radial water maze; COx; cytochrome c oxidase histochemistry; HPA; hypothalamic-pituitary-adrenal axis; GC; glucocorticoids; LTP; long-term potentiation; EPM; elevated plus-maze; C
Keywords: BrdU; 5-bromo-2-deoxyuridine; DCX; doublecortin; DG; dentate gyrus; EEAK; ethanolic extract of Acanthopanax koreanum; EPM; elevated plus-maze test; FST; forced swimming test; HPA axis; hypothalamic-pituitary-adrenal axis; NPY; neuropeptide Y; PBS; phospha
Keywords: HPA; hypothalamic-pituitary-adrenal; LPS; lipopolysaccharide; COR; corticosterone; SSRI; selective serotonin reuptake inhibitor; FLX; fluoxetine; PND; postnatal day; OF; open field; IZT; inner zone time; IZE; inner zone entries; EPM; elevated plus-maze; O
Keywords: TBI; traumatic brain injury; physical-TBI; physical-traumatic brain injury; blast-TBI; blast-traumatic brain injury; DAI; diffuse axonal injury; NOR; novel object recognition; EPM; elevated plus maze; PA; passive avoidance; PD; Parkinson's disease; AD; Al
Keywords: CD11b; cluster of differentiation molecule 11B; CHD; chow diet; CORT; corticosterone; EPM; elevated plus maze task; GR; glucocorticoid receptor; HFD; high-fat diet; HPA; hypothalamic-pituitary-adrenal; IkBa; I-kappa-B-alpha; IL-1Ra; interleukin-1 Rece
Keywords: Fear conditioning; Fear extinction; Chronic stress; Repeated restraint; Adolescent; Amygdala; ANOVA; Analysis of Variance; BLA; basolateral amygdala; CRF; corticotropin-releasing factor; EPM; elevated plus maze; HPA axis; hypothalamic-pituitary-adrenal ax
Keywords: AcN; arcuate nucleus; AMYG; amygdala; AS; appetite suppression; BB; beam-break sensor; CA3; cornu ammonis 3; CORT; corticosterone; DA; dorsal area; ENK; enkephalin; EPM; elevated plus maze; HPA; hypothalamic-pituitary-adrenal; HPC; hippocampus; HT; hy
Keywords: 5-HT; 5-Hydroxytryptamine or serotonin; AA-5-HT; N-arachidonoyl-serotonin; ACEA; arachidonoyl 2â²-chloroethylamide; AEA; N-arachidonoylethanolamine; 2-AG; 2-arachidonoylglycerol; AM251; N-(piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-
Keywords: Zinc chloride; l-Arginine; l-NAME; Anxiety; EPM; Rat
Altered Schaedler flora mice: A defined microbiota animal model to study the microbiota-gut-brain axis
Keywords: ASF; altered Schaedler Flora; CR; conventionally-reared; EPM; elevated plus maze; OF; open field; GF; germ-free; Altered Schaedler flora; Gnotobiotic; Behaviour; Microbiota-gut-brain axis; Anxiety; Stress;
Achyranthes aspera Linn. alleviates cerebral ischemia-reperfusion-induced neurocognitive, biochemical, morphological and histological alterations in Wistar rats
Keywords: AP-1; activator protein-1; BCCO; bilateral common carotid occlusion; LD50; lethal dose 50%; DCFH-DA; dichloro-dihydro-fluorescein diacetate; DMEM; dulbecco's modified eagle medium; DPI; diphenylene iodonium; DPPH; 2, 2-diphenyl-1-picrylhydrazyl; DTNB; 5,5
Tert-butyl 4-((1-phenyl-1H-pyrazol-4-yl) methyl) piperazine-1-carboxylate (LQFM104)- New piperazine derivative with antianxiety and antidepressant-like effects: Putative role of serotonergic system
Keywords: 5-HT; 5-hydroxytryptamine (serotonin; EPM; elevated plus maze; FST; forced swimming test; LQFM104; tert-butyl 4-((1-phenyl-1H-pyrazol-4-ylmethyl) piperazine-1-carboxylate; OAE; open arms entries; OFT; open field test; pCPA; p-chlorphenylalanine; TAE; to
Sacred Maya incense, copal (Protium copal - Burseraceae), has antianxiety effects in animal models
Keywords: EPM; elevated plus maze; CER; conditioned emotional response; SI; social interaction; NOR; novel object recognition; eCB; endocannabinoid; MAGL; monoacyl glyercol lipase; ANOVA; one-way analysis of variance; Protium copal; Incense; Anxiety; Elevated plus
Cananga odorata essential oil reverses the anxiety induced by 1-(3-chlorophenyl) piperazine through regulating the MAPK pathway and serotonin system in mice
Keywords: YYO; ylang-ylang essential oil; m-CPP; 1-(3-chlorophenyl) piperazine; ICR; institute of cancer research; GC/MS; gas chromatograph-mass spectrometer; MAPK; mitogen-activated protein kinase; ERK1/2; extracellular signal-regulated kinase 1/2; CREB; cAMP resp
Stress-induced hippocampus Npas4 mRNA expression relates to specific psychophysiological patterns of stress response
Keywords: AdorA1; adenosine receptor A1; ANOVA; analysis of variance; Arbp; ribosomal protein large P0; AID; activity-regulated inhibitor of death; Arc; activity-regulated cytoskeleton; Bcl2; B-cell lymphoma 2; Bdnf; brain-derived neurotrophic factor; c-fos; FBJ os
FAAH inhibition attenuates TLR3-mediated hyperthermia, nociceptive- and anxiety-like behaviour in female rats
Keywords: AEA; anandamide; ADT; acetone drop test; CB1; cannabinoid receptor 1; CB2; cannabinoid receptor 2; CD11b; cluster of differentiation molecule; 11b; CD68, cluster of differentiation 68; CNS; central nervous system; COX-2; cyclooxygenase 2; EPM; elevated pl
Differential impact of Met receptor gene interaction with early-life stress on neuronal morphology and behavior in mice
Keywords: Early-life stress; Gene à environment interaction; MET receptor tyrosine kinase; Social-emotional behavior; Neuronal morphology; ASD; autism spectrum disorders; BLA; basolateral amygdala; vHC; ventral hippocampus; DSI; direct social interaction; ELS; ear
CRMP2-Neurofibromin Interface Drives NF1-related Pain
Keywords: ANOVA; analysis of variance; AP; action potential; Cas9; CRISPR-associated protein-9 nuclease; CaV2.2; N-type voltage-gated calcium channel; CGRP; calcitonin gene-related peptide; CNRP1; CRMP2-neurofibromin regulating peptide 1; CRISPR; clustered regula
Sex-specific effects of CB1 receptor antagonism and stress in adolescence on anxiety, corticosterone concentrations, and contextual fear in adulthood in rats
Keywords: CB1; cannabinoid receptor type-1; PFC; prefrontal cortex; DH; dorsal hippocampus; PND; postnatal day; AM251; 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide; CORT; corticosterone; GAD67; glutamic acid decarboxyla
Age at injury and genotype modify acute inflammatory and neurofilament-light responses to mild CHIMERA traumatic brain injury in wild-type and APP/PS1 mice
Keywords: AD; Alzheimer's disease; APP; amyloid precursor protein; BM; Barnes maze; CCI; controlled cortical impact; CTE; chronic traumatic encephalopathy; DAI; diffuse axonal injury; EPM; elevated plus maze; GCS; Glasgow Coma Scale; FP; fluid percussion; ISF; inte
PTEN-Dependent Stabilization of MTSS1 Inhibits Metastatic Phenotype in Pancreatic Ductal Adenocarcinoma
Keywords: 3T3; NIH3T3 mouse fibroblast cells; CAF; cancer-associated fibroblast; CAFM; CAF-conditioned media; CHX; cyclohexamide; DMSO; dimethyl sulfoxide; EpM; epithelial-conditioned media; IgG; immunoglobulin G; IP; immunoprecipitate; MOE; MTSS1 overexpression; M
Neuropharmacological effects of essential oil from the leaves of Croton conduplicatus Kunth and possible mechanisms of action involved
Keywords: ATP; atropine; CNS; central nervous system; DZP; diazepam; EO; essential oil (EO); EPM; elevated plus maze; FLU; flumazenil; GC-MS; gas chromatograph interfaced to a mass spectrometer; INDO; indomethacin; MOR; morphine; NECA; number of entries in the clos
Sclerostin deficiency modifies the development of CKD-MBD in mice
Keywords: α-SMA; alpha smooth muscle actin; AjAR; adjusted apposition rate; B.Ar; bone area; BFR; bone formation rate; cbfa1; core binding factor 1; CKD-MBD; chronic kidney disease and mineral bone disorder; EPm; eroded perimeter; Ntx; nephrectomy; O.Ar; osteoid a
Involvement of SNARE complex in the hippocampus and prefrontal cortex of offspring with depression induced by prenatal stress
Keywords: Prenatal stress; Depression; SNARE protein; vGluT1; ADHD; attention deficit hyperactivity disorder; CSPα; cysteine-string protein-α; EAAT; excitatory amino acid transporter; EPM; elevated plus maze; FST; forced swimming test; Munc-18; mammalian uncoordi
Hypobaric Hypoxia-Induced Learning and Memory Impairment: Elucidating the Role of Small Conductance Ca2+-Activated K+ Channels
Keywords: aCSF; artificial cerebrospinal fluid; BSA; bovine serum albumin; CA; Cornu Ammonis; CV; Cresyl Violet staining; DG; dentate gyrus; DPX; distyrene, a plasticizer, and xylene; EPM; Elevated plus Maze; FJ B staining; Fluoro jade B staining; HH; Hypobaric Hyp
Mice deficient in AKAP13 (BRX) develop compulsive-like behavior and increased body weight
Keywords: MB; marble burying; OF; open-field; EPM; elevated plus-maze; BRX; Obsessive-compulsive disorder; Estrogen; Anxiety; AKAP13; Obesity;
Acute Stress Persistently Alters Locus Coeruleus Function and Anxiety-like Behavior in Adolescent Rats
Keywords: CNS; central nervous system; CRF; corticotropin-releasing factor; EPM; elevated plus maze; fMRI; Functional magnetic resonance imaging; LC; locus coeruleus; MAOIs; monoamine oxidase inhibitors; NE; norepinephrine; OFT; open-field test; PBS; phosphate-buff
An improved procedure for integrated behavioral z-scoring illustrated with modified Hole Board behavior of male inbred laboratory mice
Keywords: ANOVA; analysis of variance; EDTA; Ethylenediaminetetraacetic acid; EPM; elevated plus maze; i.p.; intra-peritoneal; LD; light-dark box; mHB; modified Hole Board; MPD; Mouse Phenome Database; OF; open field; RIA; radio-immunoassay; SD; standard deviation;
Aloysia citrodora Paláu (Lemon verbena): A review of phytochemistry and pharmacology
Keywords: AC; Aloysia citrodora; Min; minimum; EO; Essential oil; MIC; minimum inhibitory concentration; AEC; aqueous extract of cedrón; Ach; acetylcholine; TBARS; thiobarbituric acid-reactive substances; CL; chemiluminescence; MDA; malondialdehyde; FRAP; ferric r
Long-lasting effects of early-life intervention in mice on adulthood behaviour, GABAA receptor subunit expression and synaptic clustering
Keywords: DG; dentate gyrus; EH; early handling; EPM; elevated plus maze; GABA; γ-aminobutyric acid; LD; laterodorsal; MS; maternal separation; NH; non-handled; PND; postnatal day; SS; somatosensory; GABAA receptors; Development; Early-life environment; Stress; In
Chemical characterization and cerebroprotective effect of methanolic root extract of Colebrookea oppositifolia in rats
Keywords: MeCO; methanolic root extract of Colebrookea oppositifolia; I/R; ischemia reperfusion; DPPH; 2, 2-diphenyl-L-picrylhydrazyl; FRAP; ferric reducing antioxidant power; ORAC; oxygen radical absorbance capacity; LPS; lipopolysaccharide; LC-MS/MS; liquid chrom
DHA Mitigates Autistic Behaviors Accompanied by Dopaminergic Change in a Gene/Prenatal Stress Mouse Model
Keywords: 5HIAA; 5-hydroxyindoleacetic acid; 5HT; 5-hydroxytryptamine; AA; arachidonic acid; ASD; Autism Spectrum Disorder; DA; dopamine; DHA; docosahexaenoic acid; DHBA; 3,4-dihydroxybenzylamine; DOPAC; 3,4-dihydroxyphenylacetic acid; EPM; Elevated plus maze; GLC;
Beneficial effects of environmental enrichment on behavior, stress reactivity and synaptophysin/BDNF expression in hippocampus following early life stress
Keywords: BDNF; brain-derived neurotrophic factor; CORT; corticosterone; EPM; elevated plus maze; EE; environmental enrichment; MS; maternal separation; NMS; no maternal separation; OFT; open field test; PND; postnatal day; SYN; synaptophysin; Early stress; Enriche
Substance P and neurotensin in the limbic system: Their roles in reinforcement and memory consolidation
Keywords: ACh; acetylcholine; BLA; basolateral amygdala; BNST; bed nucleus of stria terminalis; CeA; central nucleus of amygdala; CPU; caudate-putamen; CPP; conditioned place preference; DA; dopamine; dPAG; dorsal part of the periaqueductal gray matter; EPM; elevat
Antagonizing the GABAA receptor during behavioral training improves spatial memory at different doses in control and chronically stressed rats
Keywords: GABA; Spatial memory; Object placement; Novel Object Recognition (NOR); Chronic stress; ANOVA; analysis of variance; BIC; bicuculline; CON; control; EPM; elevated plus maze; GABA; γ-aminobutyric acid; ITI; inter-trial-interval; OF; open field; OP; object
Research articleInhibiting medial septal cholinergic neurons with DREADD alleviated anxiety-like behaviors in mice
Keywords: ChAT; choline acetyltransferase; CNO; clozapine N-oxide; DREADD; designer receptors exclusively activated by designer drugs; EPM; elevated plus-maze; MB; marble burying; MS; medial septum; NSF; novelty-suppressed feeding; OF; open field; PFA; paraformalde
Synthetic cathinones and stereochemistry: S enantiomer of mephedrone reduces anxiety- and depressant-like effects in cocaine- or MDPV-abstinent rats
Keywords: Cathinone; Cocaine; Mdpv; Mephedrone; Epm; Anxiety; Depression; 5-HT;
Morphine administration induces change in anxiety-related behavior via Wnt/β-catenin signaling
Keywords: FZD; frizzled family of wnt receptor; BSA; bovine serum albumin; DMEM; dulbecco's modificationof eagle's medium; EPM; elevated plus maze test; β-catenin; Morphine; DKK1; Dendritic spine; Anxiety; HT22 cells;