Keywords: پروتئین کیناز تنظیم شده خارج سلولی; AFib; atrial fibrillation; TSG; tumor suppressor gene; CM; cardiomyocytes; GWAS; genome-wide association studies; SR; sinus rhythm; SNP; small nucleotide polymorphism; ECRG4; esophageal cancer related gene-4; ZFHX3; zinc finger homeobox protein-3; Cx; con
مقالات ISI پروتئین کیناز تنظیم شده خارج سلولی (ترجمه نشده)
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Keywords: پروتئین کیناز تنظیم شده خارج سلولی; GR; glutathione reductase; ROS; reactive oxygen species; 2-AAPA; 2-Acetylamino-3-[4-(2-acetylamino-2-carboxyethylsulfanylcarbonylamino) phenyl carbamoylsulfanyl] propionic acid; EMT; epithelial-to-mesenchymal transition; FBS; fetal bovine serum; PBS; phos
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; Curcumin; Neuropathic pain (NP); Inflammatory pain; Depression; Bioavailability; ACE; angiotensin converting enzyme; AP-1; activator protein-1; AKT; protein kinase B; BDMC; bisdemethoxycurcumin; BDNF; brain-derived neurotrophic factor; CAT; catalase; CS;
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; Apoptosis; Bone morphogenetic protein 4; Extracellular regulated protein kinases; Endothelial cells; Hyperphosphatemia
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; Epigenetic dynamics; Immune system; Autoimmune diseases; DNA methylation; Histone modifications; DNMT; DNA methyltransferase; TET; ten-eleven translocation; AID/AICDA; activation-induced cytidine deaminase; APOBEC; Apolipoprotein B mRNA editing enzyme; BE
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; EGF; epidermal growth factor; DPBS; dulbecco's phosphate-buffered saline; DMEM; dulbecco's modified eagle medium; TBST; Tween 20/Tris-buffered saline; TGF-β1; transforming growth factor beta1; MAPK; mitogen-activated protein kinases; ERK; extracellular r
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; ACP; antegrade cerebral perfusion; AMES; assisted movement with enhanced sensation; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid; BAIPC; bilateral arm ischemic preconditioning; BBB; blood-brain barrier; BCI; Brain-Computer Interface; B
Identification and mechanism evaluation of a novel osteogenesis promoting peptide from Tubulin Alpha-1C chain in Crassostrea gigas
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; MTT; 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide; ALP; alkaline phosphatase; UPLC; Ultra Performance Liquid Chromatography; Q-TOF-MS; Quadrupole time-of-flight mass spectrum; MS/MS; tandem mass spectrometry; PTH; parathyroid hormone;
Phoenixin participated in regulation of food intake and growth in spotted scat, Scatophagus argus
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; Pnx; phoenixin; ghrhr; growth hormone-releasing hormone receptor; gh; growth hormone; ghr; growth hormone receptor; Igf; insulin-like growth factor; Ghrh; growth hormone-releasing hormone; PVN; paraventricular nucleus; Arc; arcuate nucleus; VMH; ventromed
Treatment-damaged hepatocellular carcinoma promotes activities of hepatic stellate cells and fibrosis through GDF15
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; TACE; transarterial chemoembolization; HCC; hepatocellular carcinoma; GDF15; growth-differentiation factor 15; HSCs; hepatic stellate cells; TGF; transforming growth factor; JNK; c-Jun N-terminal kinase; pHSCs; primary hepatic stellate cells; DMEM; Dulbec
Cancer-associated fibroblasts-stimulated interleukin-11 promotes metastasis of gastric cancer cells mediated by upregulation of MUC1
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; IL-11; Interleukin 11; GC cells; gastric cancer cells; CAFs; cancer associated fibroblasts; STAT3; Signal Transducer and Activator of Transcription3; ERK; extracellular regulated protein kinases; KM-Plotter; Kaplan-Meier Plotter; EMT; epithelial to mesenc
Complement receptor 3 mediates NADPH oxidase activation and dopaminergic neurodegeneration through a Src-Erk-dependent pathway
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; Aβ; β-amyloid; CNS; central nervous system; CR3; complement receptor 3; DAMPs; damage associated molecular patterns; DEPs; diesel exhaust particles; DHE; dihydroethidium; Erk; extracellular regulated protein kinases; HMGB1; high-mobility group box 1; Ib
Ubiquitination and SUMOylation in the chronic inflammatory tumor microenvironment
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; Inflammation-associated cancer; Ubiquitin-proteasome system (UPS); Small ubiquitin-like modifier (SUMO); Tumor microenvironment; Cytokine profile; Transcription factors; 15d-PGJ2; 15-Deoxy-Delta-12,14-prostaglandin J2; AR; androgen receptor; Ala; alanine;
Central role of dysregulation of TGF-β/Smad in CKD progression and potential targets of its treatment
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; ACE2; angiotensin-converting enzyme-2; AGE; advanced glycation end-product; AT1R; angiotensin type 1 receptor; BMP; bone morphogenetic proteins; BMP-7; bone morphogenetic protein 7; CKD; chronic kidney diseases; Co-Smads; common mediator Smads; ECM; extra
ALA-PDT suppressed the cell growth by Akt-/Erk-mTOR-p70 s6k pathway in human SZ95 sebocytes in vitro
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; ALA; 5-aminolevulinicacid; PDT; photodynamictherapy; mTOR; mammalian targetof rapamycin; p70; S6 K p70S6Kinase p70S6; 4E-BP1; eukaryotic translation initiation factor 4E-binding protein 1; IGF; insulin-likegrowthfactor; AMPK; AMP-activated protein kinase;
Discovery of 4-((N-(2-(dimethylamino)ethyl)acrylamido)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide (CHMFL-PDGFR-159) as a highly selective type II PDGFRα kinase inhibitor for PDGFRα driving chronic eosinophilic leukemia
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; PDGFR kinase; Type II inhibitor; Kinase inhibitor; CEL; PDGFR; platelet-derived growth factor receptor; RTK; Receptor Tyrosine Kinases; ABL kinase; Abelson kinase; KIT kinase; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; RTK; receptor ty
Knockdown the P2X3 receptor in the stellate ganglia of rats relieved the diabetic cardiac autonomic neuropathy
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; Diabetic cardiac autonomic neuropathy; P2X3 shRNA; Stellate ganglia; Neurons; DCAN; Diabetic cardiac autonomic neuropathy; shRNA; Short hairpin RNA; IL-1β; Interleukin-1beta; TNF-α; Tumor necrosis factor alpha; SG; Stellate ganglion; T2DM; Type 2 diabet
Dectin-1 mediates the immunoenhancement effect of the polysaccharide from Dictyophora indusiata
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; DIP; Dictyophora indusiata polysaccharide; TLR4; toll-like re-ceptor-4; NF-κB; nuclear factor of kappa b; TNF-α; tumor necrosis factor-α; IL; interleukin; CR3; complement receptor type 3; FBS; fetal bovine serum; LPS; lipopolysaccharide; FITC; fluoresc
TNF-α suppresses osteogenic differentiation of MSCs by accelerating P2Y2 receptor in estrogen-deficiency induced osteoporosis
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; TNF-α; tumor necrosis factor-α; 1,25(OH)2D3; 1,25-dihydroxyvitamin D3; MSCs; mesenchymal stem cells; OVX; ovariectomized; anti-TNF-α; TNF-α neutralized antibody; ERK; extracellular regulated protein kinases; JNK; c-Jun N-terminal kinase; HE; hematoxyl
Ilex asprella aqueous extracts exert in vivo anti-inflammatory effects by regulating the NF-κB, JAK2/STAT3, and MAPK signaling pathways
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; ASA; Acetylsalicylic acid; DAB; tetrahydrochloride dehydrate; Dex; dexamethasone; ELISA; enzyme-linked immunosorbent assay; ERK 1/2; extracellular regulated protein kinases; HE; hematoxylin-eosin; IA; Ilex asprella; IL-6; interleukin-6; IL-1β; interleuki
Structural characterization and immunomodulatory activity of a pectic polysaccharide (CALB-4) from Fructus aurantii
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; TCM; traditional Chinese medicine; PBMCs; human peripheral blood mononuclear cells; GC-MS; gas chromatography-mass spectrometry; IR; infrared spectroscopy; SEM; scanning electron microscopy; MAPKs; mitogen-activated protein kinases; TNF-α; tumor necr
Adipokine apelin ameliorates chronic colitis in Il-10â/â mice by promoting intestinal lymphatic functions
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; CD; Crohn's disease; IBD; inflammatory bowel disease; MAT; mesenteric adipose tissue; Il-10â/â; Il-10 deficient; WT; wild type; LV; lymphatic vessel; BV; blood vessel; VEGF-C; vascular endothelial growth factor C; Erk; extracellular regulated protei
Schisandrin rescues depressive-like behaviors induced by chronic unpredictable mild stress via GDNF/ERK1/2/ROS and PI3K/AKT/NOX signaling pathways in mice
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; CUMS; Chronic unpredictable mild stress; GDNF; Glial cell line-derived neurotrophic factor; TGF-β; Transforming growth factor-beta; ERK; Extracellular regulated protein kinases; PERK; Phosphorylase extracellular regulated protein kinases; NOX; NADPH oxid
MiR-212-3p inhibits LPS-induced inflammatory response through targeting HMGB1 in murine macrophages
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; LPS; lipopolysaccharide; TLRs; Toll-like receptors; HMGB1; high mobility group box 1; miRNAs; microRNAs; mRNAs; messenger RNAs; siRNA; small interfering RNA; UTR; untranslated region; Mut; mutated; TNF-α; tumor necrosis factor-alpha; IL-6; interleukin-6;
Ethanol extract of Atractylodis macrocephalae Rhizoma ameliorates insulin resistance and gut microbiota in type 2 diabetic db/db mice
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; T2DM; Type 2 diabetes mellitus; IR; insulin resistance; PI3K; phosphatidylinositol-3-kinase; AKT; protein kinase B; TNF-α; tumor necrosis factor-alpha; IL-1β; interleukin 1-beta; NF-κB; nuclear factor-kappa B; AMK; Atractylodes macrocephala Koidz; IL-6
Nrf-2-driven long noncoding RNA ODRUL contributes to modulating silver nanoparticle-induced effects on erythroid cells
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; Silver nanoparticles; lncRNA; ODRUL; Cell death; Erythroid cells; AKT; protein kinase B (PKB); Bcl-2; B-cell lymphoma-2; CAT; Catalase; ERK; extracellular regulated protein kinases; HO-1; hemeoxygenase; JNK; c-Jun N-terminal kinase; LncRNA; long non-codin
Rac1 signaling regulates cigarette smoke-induced inflammation in the lung via the Erk1/2 MAPK and STAT3 pathways
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; COPD; chronic obstructive pulmonary disease; CS; cigarette smoke; CSE; cigarette smoke extract; IL-6; interleukin-6; IL-8; interleukin-8; KC; keratinocyte-derived chemokine; NSC; NSC23766, Rac1 inhibitor; Erk1/2; extracellular regulated protein kinases; M
Insulin-like growth factor 1 promotes the proliferation and committed differentiation of human dental pulp stem cells through MAPK pathways
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; ALP; alkaline phosphatase; a-MEM; a-minimum essential medium; BMPs; bone morphogenetic proteins; CPC; cetyl pyridinium chloride; DSP; dentin sialoprotein; DSPP; dentin sialophosphoprotein; ERK; extracellular regulated protein kinases; FBS; fetal bovine se
PKG-1α mediates GATA4 transcriptional activity
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; GATA4; GATA binding protein 4; NPPA; natriuretic peptide A; NPPB; natriuretic peptide B; MHC; myosin heavy chain; ERK; extracellular regulated protein kinases; p38 MAPK; p38 mitogen-activated protein kinases; PKC; protein kinase C; GSK 3β; glycogen synth
Intrathecal administration of rapamycin inhibits the phosphorylation of DRG Nav1.8 and attenuates STZ-induced painful diabetic neuropathy in rats
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; STZ; streptozotocin; PDN; painful diabetic neuropathy; DRG; dorsal root ganglion; mTOR; mammalian target of rapamycin; S6K; ribosomal protein S6 kinase; 4E-BP; eukaryotic initiation factor 4E (eIF4E) binding protein; IR; insulin receptor; IRS-1; insulin r
The modulatory effect of TLR2 on LL-37-induced human mast cells activation
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; LL-37; Toll-like receptor 2 (TLR2); Human mast cells; ERK; extracellular regulated protein kinases; JNK; c-Jun N-terminal kinase; MAPKs; mitogen-activated protein kinases; PKC; protein kinase C; PLC; phospholipase C;
The activation of the NF-κB-JNK pathway is independent of the PI3K-Rac1-JNK pathway involved in the bFGF-regulated human fibroblast cell migration
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; bFGF; basic Fibroblast Growth Factor; NF-κB; nuclear factor kappa B; c-JNK; Jun N-terminal kinase; PI3 K; phosphatidylinositol 3-kinase; FGFR; fibroblast growth factor receptor; RNA-Seq; RNA-Sequencing; IκB-α; inhibitor of nuclear factor kappa B-alpha;
A novel anti-inflammatory mechanism of high density lipoprotein through up-regulating annexin A1 in vascular endothelial cells
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; HDL; high-density lipoprotein; CVD; cardiovascular disease; NO; nitric oxide; ROS; reactive oxygen species; TNF-α; tumor necrosis factor α; HUVECs; human umbilical vein endothelial cells; ANXA1; annexin A1; ANXA5; annexin A5; SR-BI; scavenger receptor c
Decrease of phosphorylated CREB and ERK in nucleus accumbens is associated with the incubation of heroin seeking induced by cues after withdrawal
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; CREB; cAMP response element binding protein; ERK; extracellular regulated protein kinases; PDE4; phosphodiesterase-4; aCSF; arificial cerebrospinal fluid; Addiction; cAMP; Opioid; Phosphodiesterase-4; Transcription factor;
Medicinal uses, phytochemistry and pharmacology of the genus Uncaria
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; U1; Uncaria acida (Hunter) Roxb; U2; Uncaria africana G. Don; U3; Uncaria attenuate Korth; U4; Uncaria barbata Merr; U5; Uncaria bernaysii F. Muell; U6; Uncaria borneensis Havil; U7; Uncaria callophylla Blume ex Korth; U8; Uncaria canescens Korth; U9; Unc
Berberine inhibits LPS-induced TF procoagulant activity and expression through NF-κB/p65, Akt and MAPK pathway in THP-1 cells
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; ALI; acute lung injury; ARDS; acute respiratory distress syndrome; BBR; berberine; DIC; disseminated intravascular coagulation; ERK; extracellular regulated protein kinases; LPS; lipopolysaccharide; MAPK; mitogen-activated protein kinases; NF-κB; nuclear
Nitidine chloride induces apoptosis and inhibits tumor cell proliferation via suppressing ERK signaling pathway in renal cancer
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; ERK; extracellular regulated protein kinases; DMSO; dimethylsulfoxide; DMEM; Dulbecco's Modified Eagle's Medium; FBS; fetal bovine serum; PBS; Phosphate Buffered Saline; PBST; Phosphate Buffered Saline and Tween 20; Nitidine chloride; Apoptosis; Renal
Cocaine- and amphetamine-regulated transcript facilitates the neurite outgrowth in cortical neurons after oxygen and glucose deprivation through PTN-dependent pathway
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; BDNF; brain-derived neurotrophic factor; CART; cocaine- and amphetamine-regulated transcript; DMEM; dulbecco's modified eagle's medium; ECL; enhanced chemiluminescence; ERK; extracellular regulated protein kinases; FBS; fetal bovine serum; GAP43; growth-a
The protective effect of smilax glabra extract on advanced glycation end products-induced endothelial dysfunction in HUVECs via RAGE-ERK1/2-NF-κB pathway
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; AGEs; advanced glycation end products; HUVECs; human umbilical vein endothelial cells; RAGE; receptor for advanced glycation end products; TGF-beta1; transforming growth factor-beta1; AO/EB; acridine orange/ethidium bromide; ERK1/2; extracellular regulate
Cigarette smoke-induced alveolar epithelial-mesenchymal transition is mediated by Rac1 activation
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; EMT; epithelial-mesenchymal transition; COPD; chronic obstructive pulmonary disease; CSE; cigarette smoke extract; TGF-β1; transforming growth factor β1; α-SMA; α-smooth muscle actin; MMP-9; matrix metalloproteinases-9; ATNA; anti-TGF-β1 neutralizi
Transdermal siRNA-TGFβ1-337 patch for hypertrophic scar treatment
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; HSc; hypertrophic scar; TGFβ1; transforming growth factor, beta 1; TGF-β2; transforming growth factor, beta 2; TGF-β3; transforming growth factor, beta 3; siRNA; small interfering RNA; G1; G1 phase of the cell cycle; LAP; latency-associated peptide; IH
Cellular and molecular mechanisms of bromate-induced cytotoxicity in human and rat kidney cells
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; Brâ; bromide; BrO3â; bromate; DAPI; 4â², 6-diamidino-2-phenylindole; CM-H2DCFDA; 5-(and-6)-chloromethyl-2â²,7â²-difluorodihydrofluorescein diacetate, acetyl ester; ERK; extracellular regulated protein kinases; MAPK; mitogen activated protein kinase
Cellular neuroscienceLipopolysaccharide plus 12-o-tetradecanoylphorbol 13-acetate induction of migration and invasion of glioma cells in vitro and in vivo: Differential inhibitory effects of flavonoids
Keywords: پروتئین کیناز تنظیم شده خارج سلولی; invasion; migration; LPS; TPA; flavonoids; MMP-9; DMSO; dimethyl sulfoxide; ECM; extracellular matrix; ERKs; extracellular regulated protein kinases; iNOS; inducible nitric oxide synthase; JNKs; c-Jun N-terminal kinases; KAE; kaempferol; LPS; lipopolysacc