Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; ADAM; a disintegrin and metalloproteinase; AKT; protein kinase B; APAF 1; apoptotic protease activating factor 1; APC; adenomatous polyposis coli; ATG; autophagy protein; BAK; Bcl 2 homologous antagonist/killer; BAX; Bcl-2 associated -X protein; Bcl-2; B-
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Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; Carcinogenesis; Chemoprevention; Chemotherapy; Oxidative stress; Nrf2; Phytochemicals; AKT; protein kinase B; AMPK; AMP-activated protein kinase; ARE; antioxidant response element; ATF-2; activating transcriptional factor; BBN; N-butyl-N-(4-hydroxybutyl)n
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; GDM; gestational diabetes mellitus; T2D; type 2 diabetes; CVD; cardiovascular disease; DOHaD; developmental origins of health and disease; CDA; Canadian diabetes association; HOMA-IR; homeostatic model assessment for insulin resistance; DINT; dietary inte
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; ABCB1; ATP-binding cassette sub-family B member 1; ABCG; ATP-binding cassette drug efflux transporters; ACD; autophagic cell death; AKT; alpha serine/threonine protein kinase; ALDH; aldehyde dehydrogenase; AMPK; AMP-activated protein kinase; AP; apurinic/
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; ERK; extracellular signal regulated kinase; FXR; farsenoid X receptor; HCC; hepatocellular carcinoma; HSCs; hepatic stellate cells; IL1β; Interleukin 1 beta; IL18; Interleukin 18; IKKβ; inhibitor of nuclear factor kappa-B kinase subunit beta; JAK; Janus
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; ACC; acetyl CoA carboxylase; ACYL; ATP citrate lyase; Akt2; rac-β-serine-threonine kinase; ALA; α-linolenic acid; ALT; alanine aminotransferase; ARA; arachidonic acid, 20:4,Ï6; AST; aspartate aminotransferase; ATGL; adipocyte triglyceride lipase; CD36;
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; 6-OHDA; 6-hydroxydopamine; CA; catecholamine; CaMKII; Ca2+/calmodulin-dependent protein kinase II; CDK; cyclin-dependent kinase; CNS; central nervous system; DA; dopamine; ENS; enteric nervous system; ERK; extracellular signal regulated kinase; GI; gastro
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; Protein kinase C; Extracellular signal regulated kinase; Protein phosphatase 1/2A; PIN1; Amphetamine; Phospho-specific antibody;
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; Aptamer; Apoptosis; Targeted therapy; Intrinsic apoptosis pathway; Extrinsic apoptosis pathway; Intramer; Akt; PKB (protein kinase B); Bcl; B-cell lymphoma family protein; BH; Bcl-2 homology domain; Bmi-1; B lymphoma Mo-MLV insertion region 1; CD; cluster
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; AD; Alzheimer's disease; ADF; alternate day fasting; ALS; amyotrophic lateral sclerosis; APP; β-amyloid precursor protein; BDNF; brain-derived neurotrophic factor; CER; continuous energy restriction; CR; caloric restriction; CREB; cyclic AMP response e
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; Sphingosine-1-phosphate; Sphingosine kinase; Estradiol; Breast cancer; FTY720/Fingolimod; ERα; estrogen receptor α; EGFR; epidermal growth factor receptor; ERE; estrogen response element; ERK; extracellular signal regulated kinase; E2; 17β-estradiol; H
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; ASC; apoptosis-associated speck-like protein containing a caspase recruitment domain; DAMPs; danger associated molecular patterns; EAE; experimental autoimmune encephalomyelitis; HER2; human epidermal growth factor related receptor 2; ERK; extracellular s
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; ACSL1; long-chain acyl-CoA synthetase 1; ATGL; adipose triglyceride lipase; CerS5; ceramide synthase 5; CPT; carnitine palmitoyltransferase; DAG; diacylglycerol; DGAT; diacylglycerol acyltransferase; ER; endoplasmic reticulum; ERK; extracellular signal re
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; AP-1; activator protein 1; APC; antigen-presenting cells; ARE; AU-rich element; ASK; Apoptosis Signal regulating Kinase; ATF-2; Activating Transcription Factor 2; CRE; Cyclic AMP Responsive Element; CBP; CREB binding protein; CsA; ciclosporin A; ERK; Extr
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; APP; amyloid precursor protein; ATF; activating transcription factor 6; CREB; cAMP response element binding protein; EC; enriched condition; EDTA; ethylenediaminetetraacetic acid; ERK; extracellular signal regulated kinase; FR1; fixed ratio 1; GO; Gene On
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; ANT; adenine nucleotide translocase; CsA; cyclosporin A; CyP; cyclophilin; Drp1; dynamin-related protein 1; ÎÏm; mitochondrial membrane potential; ERK; extracellular signal regulated kinase; GSK; glycogen synthase kinase; IMM; inner mitochondrial membra
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; Membrane; Lipid; Receptor; Membrane properties; Signaling; Host-pathogen; AC; adenylyl cyclase; CaMK; Ca2+-calmodulin-dependent protein kinase; cAMP; cyclic adenosine monophosphate; ChOx; cholesterol oxidase; CREB; cAMP response element-binding protei
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; 4-HPR; N-(4-hydroxyphenyl)retinamide; 5â²-UTR; 5â²-untranslated region; 9-cis-RA; 9-cis retinoic acid; 9cUAB30; (2E,4E,6Z,8E)-8-(3â²,4â²-dihydro-1â²(2'H)-naphthalen-1â²-ylidene)-3,7-dimethyl-2,4,6-octatrienoic acid; Acitretin; (2E,4E,6E,8E)-9-(4-met
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; Anti-Inflammatory; Angiotensin II; Angiotensin receptor blocker; Extracellular signal regulated kinase; Atheroma; Cytokine;
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; AP-1; activator protein 1; Dusp; dual-specificity phosphatase; Egr1; early growth response protein 1; ERK; extracellular signal regulated kinase; F2-KO mice; flotillin-2 knockout mice; Flot-1; flotillin-1; Flot-2; flotillin-2; HB-EGF; Heparin Binding-EGF;
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; 7-KC; 7 ketocholesterol; ACAT; acyl-CoA cholesterol acyl transferase; CHEH; cholesterol-5-6-epoxide hydrolase; CNS; central nervous system; CT; cholestane 3β-5α-6β triol; EC; epoxycholesterol; EGF; epidermal growth factor; ER; endoplasmic reticulum; ER
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; CBZ; carbamazepine; PHx; partial hepatectomy; PI-3K; phosphotidylinositol-3 kinase; MAPK; ras-mitogen-activated protein kinase; ERK; extracellular signal regulated kinase; DMSO; dimethyl sulfoxide; H&E; haematoxylin and eosin; IHC; immunohistochemistry; R
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; Ap3A; diadenosine triphosphate; ERK; extracellular signal regulated kinase; FHIT; fragile histidine triad protein; GSSG; oxidized glutathione; GSH; reduced glutathione; LC3; microtubule associated protein 1 light chain 3; NAC; N-acetyl-cysteine; NADPH; ni
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; AC; adenylyl cyclase; BAT; brown adipose tissue; BMP; bone morphogenetic protein; BST; bed nucleus of the stria terminalis; CB1R; cannabinoid receptor type 1; CNS; central nervous system; CREB; cAMP-response element binding protein; DRN; dorsal raphe nucl
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; 4E-BP1; 4E-binding protein-1; AA; amino acid; ALS; autophagy-lysosomal system; AMPK; adenosine monophosphate-activated protein kinase; COPD; chronic obstructive pulmonary disease; CRP; C-reactive protein; ERK; extracellular signal regulated kinase; FFM; f
The cross roles of sphingosine kinase 1/2 and ceramide glucosyltransferase in cell growth and death
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; Sphingosine kinases 1 and 2; Sphingosine; S1P; Ceramide; Ceramide glucosyltransferase; Cell cycle; Anti-cancer; SK1; sphingosine kinases 1; SK2; sphingosine kinases 2; PCNA; proliferating cell nuclear antigen; GSL; glycosphingolipids; Cer; Ceramide; Sph;
The effects of glucose concentrations associated with lipopolysaccharide and interferon-gamma stimulus on mediators' production of RAW 264.7 cells
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; AGE; advanced glycation end-products; α-MEM; minimum essential medium alpha medium; ANOVA; analysis of variance; DM; Diabetes Mellitus; DMSO; dimethylsulfoxide; ELISA; enzyme-linked immunosorbent assay; ERK; extracellular signal regulated kinase; IL; int
Pharmacological effects and potential therapeutic targets of DT-13
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; ADP; adenosine diphosphate; Akt; protein kinsase B; ALT; alanine transaminase; APD; action potential duration; AST; aspartate transaminase; Atg; autophagocytosis associated protein; CCR5; C, C chemokine receptor type 5; CXCR4; C-X-C chemokine receptor typ
Cathepsin D non-proteolytically induces proliferation and migration in human omental microvascular endothelial cells via activation of the ERK1/2 and PI3K/AKT pathways
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; EOC; epithelial ovarian cancer; CathD; cathepsin D; EC; endothelial cell; ERK1/2; extracellular signal regulated kinase; AKT; protein kinase B; CAM; chorioallontoic membrane model; ECM; extracellular matrix; Cathepsin D; Non-proteolytic; Proliferation; Mi
Alterations of MEK1/2-ERK1/2, IFNγ and Smad2/3 associated Signalling pathways during cryopreservation of ASCs affect their differentiation towards VSMC-like cells
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; ASC; Adipose derived stromal cells; α-SMA; α-smooth muscle actin.; CA; Cryopreserved ASCs.; FA; Fresh ASCs.; IFNγ; Interferon gamma.; NE; Norepinephrine.; RA; Retinoic acid.; SM22α; Smooth muscle 22α.; SMMHC; Smooth muscle myosin heavy chain.; TEVG;
Comprehensive review on flavonoids biological activities of Erythrina plant species
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; 5-LOX; 5-lipoxygenase; AMPK; adenosine monophosphate-activated protein kinase; Bax; Bcl-2-associated X protein; BC; lymphoma cell line; Bcl-2; B-cell CLL/lymphoma 2; Caco2; human epithelial colorectal adenocarcinoma cells; CCRF-CEM; T lymphoblastoid cell
Activation of renal profibrotic TGFβ controlled signaling cascades by calcineurin and mTOR inhibitors
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; AP-1; activator protein 1; CNI; calcineurin inhibitor(s); ECM; extracellular matrix; EMT; epithelial to mesenchymal transition; ERK; extracellular signal regulated kinase; FKBP; FK506 binding protein; JNK; Jun N-terminal kinase; LAP; latency-associated pr
The traditional uses, phytochemistry, and pharmacology of Atractylodes macrocephala Koidz.: A review
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; AM; Atractylodes macrocephala Koidz.; TCM; traditional Chinese medicine; UPLC; ultra-performance liquid chromatography; PDA; photo-diode array; IR; infrared spectroscopy; HS-LP-LPE; headspace liquid phase-liquid-phase extraction; GC-MS; gas chromatography
Activation of Nrf2 signaling by natural products-can it alleviate diabetes?
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; Nrf2; type 2 diabetes; natural products; hyperglycemia; cellular stress; insulin sensitivity; β-cell function; vascular complications; AGE; advanced glycation end products; AhR; arylhydrocarbon receptor; AMPK; AMP-activated kinase; ARE; antioxidant respo
Contrary influence of clinically applied sorafenib concentrations among hepatocellular carcinoma patients
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; HCC; hepatocellular carcinoma; MAPK; mitogen-activated protein kinase; ERK; extracellular signal regulated kinase; MEK; MAPK (ERK) kinase; RT-PCR; reverse transcriptase-polymerase chain reaction; Angiogenesis; Hepatocellular carcinoma; KDR; PDGFRB; Prolif
Research articlePioglitazone improves the ability of learning and memory via activating ERK1/2 signaling pathway in the hippocampus of T2DM rats
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; Pioglitazone; Extracellular signal regulated kinase; Raf-1 kinase inhibitory protein; Type 2 diabetes mellitus; Learning and memory;
Research paperResveratrol promotes human embryonic stem cells self-renewal by targeting SIRT1-ERK signaling pathway
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; bFGF; basic fibroblast growth factor; BrdU; 5 bromo-2-deoxyuridine; EB; embryoid body; ERK; extracellular signal regulated kinase; EX-527; 6-chloro-2 3 4 9-tetrahydro-1H-carbazole-1-carboxamide; hESCs; Human embryonic stem cells; iPSCs; induced pluripoten
MAPK activation patterns of AT1R and CB1R in SHR versus Wistar astrocytes: Evidence of CB1R hypofunction and crosstalk between AT1R and CB1R
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; ADHD; Attention Deficit Hyperactivity Disorder; MAPK; Mitogen-activated protein kinases; ALAAC; Association for Assessment and Accreditation of Laboratory Animal Care International; Ang; Angiotensin; AT1R; Ang type 1 receptor; AT2R; Ang type 2 receptor; B
Tert-butyl hydroperoxide (t-BHP) induced apoptosis and necroptosis in endothelial cells: Roles of NOX4 and mitochondrion
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; AA; Antimycin A; ALL; Allopurinol; ASK1; Apoptosis-signaling kinase 1; DCFH2-DA; 5-(6)-carboxy-2â², 7â²-dichlorodihydrofluorescein diacetate; DPI; Diphenyleneiodonium; ERK; Extracellular signal regulated kinase; H2O2; Hydrogen peroxide; JNK; c-Jun-N-ter
Loss of dopamine D1 receptors and diminished D1/5 receptor-mediated ERK phosphorylation in the periaqueductal gray after spinal cord lesion
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; DRM; detergent-resistant membranes; DSM; detergent-soluble membranes; ERK1,2; extracellular signal-regulated protein kinases 1 and 2; pERK1,2; phosphorylated ERK 1 and 2; i.p.; intraperitoneal; IPSC; inhibitory post-synaptic potential; PAG; periaqueductal
Cynandione A attenuates neuropathic pain through p38β MAPK-mediated spinal microglial expression of β-endorphin
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; POMC; proopiomelanocortin; GLP-1; glucagon-like peptide-1; GPR40; G-protein receptor 40; CRF; corticotropin-releasing factor; MAPKs; mitogen-activated protein kinases; ERK1/2; extracellular signal regulated kinase; JNK; c-Jun N-terminal kinase; IL-1β; in
Wogonin, a plant derived small molecule, exerts potent anti-inflammatory and chondroprotective effects through the activation of ROS/ERK/Nrf2 signaling pathways in human Osteoarthritis chondrocytes
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; IL-1β; Interleukin-1β; IL-6; Interleukin-6; MMP; Matrix Metalloproteinase; ADAMTS; A Disintegrin and Metalloproteinase with Thrombospondin Motifs; COX-2; Cyclo-oxygenase-2; iNOS; Inducible Nitric Oxide Synthase; PGE2; Prostaglandin E2; COL2A1; Type 2 Co
Targeting GPNMB with glembatumumab vedotin: Current developments and future opportunities for the treatment of cancer
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; AE; Adverse Event; α-MSH; alpha-Melanocyte Stimulating Hormone; ADC; Antibody-Drug Conjugate; ASPS; Alveolar Soft Part Sarcoma; ASPSCR1; Alveolar Soft Part Sarcoma Chromosome Region Candidate 1; BMP-2; Bone Morphogenetic Protein-2; BRK; Breast Tumor Kina
The multi-site docking protein Gab1 is constitutively phosphorylated independent from its recruitment to the plasma membrane in Jak2-V617F-positive cells and mediates proliferation of human erythroleukaemia cells
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; AEBSF; 4-(2-aminoethyl)-benzolsulfonylfluorid; DMEM; Dulbecco's modified Eagle's medium; EGFR; epidermal growth factor receptor; Epo; erythropoietin; EpoR; erythropoietin receptor; Erk; extracellular signal regulated kinase; FCS; fetal calf serum; Gab1; G
Phosphatidylethanolamine binding protein 4 (PEBP4) is a secreted protein and has multiple functions
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; Act; protein kinase B; DMEM; Dulbecco's modified Eagle's medium; EGF; epidermal growth factor; ERK; extracellular signal regulated kinase; FBS; fetal bovine serum; GFP; green fluorescent protein; Her2; human epidermal growth factor receptor 2; HMGB1; high
The Asian-American variant of human papillomavirus type 16 exhibits higher activation of MAPK and PI3K/AKT signaling pathways, transformation, migration and invasion of primary human keratinocytes
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; (Af); African; (As); Asian; (AA); Asian-American; (CREB); cAMP response element-binding protein; (CIN); cervical intraepithelial neoplasia; (EMT); Ephitelial to mesenchymal transition; (E); European; (E-P); European prototype; (ERK2); extracellular signal
Insights into the development and regulation of T follicular helper cells
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; Th; T helper; Tfh; T follicular helper; IL; interleukin; Ig; Immunoglobulin; STAT; signal transduction and activator of transcription; ICOS; inducible co-stimulator; SLAM; signaling lymphocytic activation molecule; SAP; slam associated protein; GC; germin
Cucurbitacin E ameliorates hepatic fibrosis in vivo and in vitro through activation of AMPK and blocking mTOR-dependent signaling pathway
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; CuE; Cucurbitacin E; ECM; extracellular matrix; HSCs; Hepatic stellate cells; TNF-α; tumor necrosis factor-α; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; PARP; poly ADP-ribose polymerase; MAPK; mitogen activated protein kinase; ER
Functional role of inorganic trace elements in angiogenesis part III: (Ti, Li, Ce, As, Hg, Va, Nb and Pb)
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; As; arsenic; FGF-2; basic fibroblast growth factor; BMP-2; bone morphogenetic protein-2; Ce; cerium; COX; cyclooxygenase; EC; endothelial cells; EPCR; endothelial cell protein C receptor; EPCs; endothelial progenitor cells; EMT; epithelial to mesenchymal
2-Methoxy-6-acetyl-7-methyljuglone (MAM), a natural naphthoquinone, induces NO-dependent apoptosis and necroptosis by H2O2-dependent JNK activation in cancer cells
Keywords: سیگنال خارج سلولی kinase را تنظیم می کند; CAT; catalase; DAF-FM; 4-amino-5-methylamino-2â²,7â²-mifluorofluorescein; DCFH2-DA; 2â²,7â²-dichlorodihydrofluorescein diacetate; DHE; dihydroethidium; DMSO; dimethyl sulfoxide; DPI; diphenyleneiodonium; ERK; extracellular signal regulated kinase; FLR