Keywords: G پروتئین گیرنده کیناز; AC; adenylate cyclase; β-AR; β-adrenergic receptor; CaM; calmoduline; cAMP; cyclic adenosine monophosphate; CHO; Chinese hamster ovary; EGFR; epidermal growth factor receptor; ERK; extracellular signal-regulated kinase; DAG; diacylglycerol; DR; dopamine
مقالات ISI G پروتئین گیرنده کیناز (ترجمه نشده)
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Keywords: G پروتئین گیرنده کیناز; λmax; absorption maximum wavelength; GRK; G protein-coupled receptor kinase; UV; ultraviolet; CHAPS; 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate; PC; l-α-phosphatidylcholine; Pi; inorganic phosphate; Cone visual pigment; Phosphorylation; G
Keywords: G پروتئین گیرنده کیناز; GPCR; G protein-coupled receptor; GRK; G protein-coupled receptor kinase; WT; wild type; Rh; dark unphosphorylated rhodopsin; Rh*; light-activated unphosphorylated rhodopsin; P-Rh; dark phosphorylated rhodopsin; P-Rh*; light-activated phosphorylated rhodo
β3-adrenergic receptor activation induces TGFβ1 expression in cardiomyocytes via the PKG/JNK/c-Jun pathway
Keywords: G پروتئین گیرنده کیناز; β3-adrenergic receptor; Transforming growth factor β1; Protein kinase G; c-Jun N-Terminal kinase; c-Jun; Cardiomyocyte; AP-1; activator protein 1; β-AR; β-adrenergic receptor; cGMP; cyclic guanosine monophosphate; GRK; G protein-coupled receptor kinas
GRK2 as negative modulator of NO bioavailability: Implications for cardiovascular disease
Keywords: G پروتئین گیرنده کیناز; Nitric oxide; β-adrenergic receptor; G protein-coupled receptor kinase; Cardiovascular system;
G protein-coupled receptor kinases: Past, present and future
Keywords: G پروتئین گیرنده کیناز; αN-helix; N-terminal α-helical domain; α2AAR; α2A-adrenergic receptor; AST; active site tether; βAR; β-adrenergic receptor; β2AR; β2-adrenergic receptor; βARK; β-adrenergic receptor kinase; CLBD; C-terminal lipid binding domain; EM; electron mic
Different mode of arrestin-3 binding at the human Y1 and Y2 receptor
Keywords: G پروتئین گیرنده کیناز; ANOVA; analysis of variance; arr; arrestin; BRET; bioluminescence resonance energy transfer; EYFP; enhanced yellow fluorescent protein; FLR; finger loop region; GPCR; G protein-coupled receptor; GRK; G protein-coupled receptor kinase; YxR; neuropeptide Yx
β-arrestin-biased agonism of β-adrenergic receptor regulates Dicer-mediated microRNA maturation to promote cardioprotective signaling
Keywords: G پروتئین گیرنده کیناز; βARs; β-adrenergic receptors; β-blockers; β-adrenergic receptor antagonists; β-miRs; β-adrenergic receptor/β-arrestin-regulated miRs; Carv; carvedilol; GPCR; G protein-coupled receptor; GRK; G protein-coupled receptor kinase; KO; knockout; MiRNAs o
Human melanocortin 1 receptor-mediated ubiquitination of nonvisual arrestins. Role of Mahogunin Ring Finger 1 E3 ligase
Keywords: G پروتئین گیرنده کیناز; ARRB; β-arrestin; β2AR; β2-adrenergic receptor; GRK; G protein-coupled receptor kinase; GPCR; G protein-coupled receptor; LOF; loss-of-function; αMSH; α melanocyte-stimulating hormone; MCR; melanocortin receptor; MC1R; melanocortin 1 receptor; MGRN1;
AGC kinases, mechanisms of regulation âand innovative drug development
Keywords: G پروتئین گیرنده کیناز; AGC kinase; group of kinases related to PKA PKG and PKC; PKA; protein kinase A; PKC; protein kinase C; PKG; protein kinase G; PRK; protein kinase C related kinase (also termed PKN protein kinase N); PDK1; 3-phosphoinositide-dependent protein kinase 1; PKB
Impact of paroxetine on proximal β-adrenergic receptor signaling
Keywords: G پروتئین گیرنده کیناز; βAR; β-adrenergic receptor; βarr; β-arrestin; EC50; half-maximal effective concentration; FRET; fluorescence resonance energy transfer; GRK; G protein-coupled receptor; IC50; half-maximal inhibitory concentration; ISO; isoproterenol; mCFP; monomeric c
C-terminal motif of human neuropeptide Y4 receptor determines internalization and arrestin recruitment
Keywords: G پروتئین گیرنده کیناز; ANOVA; analysis of variance; arr; arrestin; BRET; bioluminescence resonance energy transfer; EYFP; enhanced yellow fluorescent protein; GPCR; G protein-coupled receptor; GRK; G protein-coupled receptor kinase; hPP; human pancreatic polypeptide; hY1R; huma
Pathophysiological consequences of receptor mistraffic: Tales from the platelet P2Y12 receptor
Keywords: G پروتئین گیرنده کیناز; ADP; Adenosine diphosphate; CNM; centronuclear myopathy; CMT; Charcot-Marie- Tooth; CAMs; constitutively active mutants; GAPP; Genotyping and Phenotyping of Platelets consortium; GPCR; G protein-coupled receptor; GRK; G protein-coupled receptor kinase
Purinergic P2Y receptors: Molecular diversity and implications for treatment of cardiovascular diseases
Keywords: G پروتئین گیرنده کیناز; ADP; adenosine 5â²-diphosphate; AgRP; agouti-related peptide; AMPK; 5â²-AMP-activated protein kinase; ApnA; diadenosine polyphosphate; ApoE; apolipoprotein E; AT1R; angiotensin II type 1 receptor; ATP; adenosine 5â²-triphosphate; BN-PAGE; blue native-p
MC1R signaling. Intracellular partners and pathophysiological implications
Keywords: G پروتئین گیرنده کیناز; AC; adenylyl cyclase; ACTH; adrenocorticotropic hormone; ARRB; β-arrestin; ASIP; agouti signal protein; CBD103; dog β-defensin-3; CREB; cAMP responsive-element binding protein; EDN1; endothelin 1; ER; endoplasmic reticulum; ERK; extracellular signal-reg
Sub-cellular localization specific SUMOylation in the heart
Keywords: G پروتئین گیرنده کیناز; AMPK; adenosine monophosphate-activated protein kinase; CAMKK; calcium-calmodulin-activated protein kinase kinase; CHIP; carboxyl terminus of HSP70-interacting protein; CVD; cardiovascular disease; cTnI; cardiac troponin I; d-flow; disturbed flow; DeSI; d
Characterization of the interaction between the dopamine D4 receptor, KLHL12 and β-arrestins
Keywords: G پروتئین گیرنده کیناز; GPCR; β-arrestin; KLHL12; ubiquitination; dopamine D4 receptor; β2AR; β2-adrenergic receptor; ADHD; attention deficit hyperactivity disorder; BTB; bric à brac 1, tramtrack, and broad-complex; co-IP; co-immunoprecipitation; CXCR4; C-X-C chemokine recep
Systematic analysis of factors influencing observations of biased agonism at the mu-opioid receptor
Keywords: G پروتئین گیرنده کیناز; AC; adenylyl cyclase; α-neo; α-neoendorphin; β-arr1 and β-arr2; β-arrestin 1 and 2; BRET; bioluminescence resonance energy transfer; CHO; Chinese hamster ovary; DAMGO; d-Ala2-N-MePhe4-Gly-ol enkephalin; endo; endomorphin; pERK; extracellular signal r
G protein-coupled receptor kinases as regulators of dopamine receptor functions
Keywords: G پروتئین گیرنده کیناز; G protein-coupled receptor kinase; Dopamine receptor; Psychostimulants; L-DOPA; Dyskinesia; Parkinsonâ¿¿s disease;
Chronic social defeat stress increases dopamine D2 receptor dimerization in the prefrontal cortex of adult mice
Keywords: G پروتئین گیرنده کیناز; AFB; animal-free blocker; AISS; amphetamine-induced sensitized-state; AMYG; amygdala; D1Rs; D1 receptors; D2Rs; D2 receptors; DLPFC; dorsolateral prefrontal cortex; EDTA; ethylenediaminetetra acetic acid; EGTA; ethylene glycol tetraacetic acid; GASP-1; G
The carboxy-terminal tail or the intracellular loop 3 is required for β-arrestin-dependent internalization of a mammalian type II GnRH receptor
Keywords: G پروتئین گیرنده کیناز; GnRH receptor; Internalization; G protein-coupled receptor kinase; β-Arrestin; ERK; DMEM; Dulbecco's modified Eagle medium; EC50; concentration that stimulates half-maximal IP production; ERK; extracellular signal-regulated kinases; FSH; follicle-stimula
The immune signaling pathways of Manduca sexta
Keywords: G پروتئین گیرنده کیناز; Insect immunity; RNA-Seq; Transcriptome; Gene annotation; Expression profiling; Atg; autophagy-related protein; aPKC; atypical protein kinase C; CF; control fat body; CH; control hemocytes; IF; induced fat body; IH; induced hemocytes; Deaf; deformed epide
PDZK1/NHERF3 Differentially Regulates Corticotropin-releasing Factor Receptor 1 and Serotonin 2A Receptor Signaling and Endocytosis
Keywords: G پروتئین گیرنده کیناز; ANOVA; analysis of variance; β 1AR; β 1-adrenergic receptor; β2AR; β2-adrenergic receptor; CRF; corticotropin-releasing factor; CRFR1; CRF receptor 1; CRFR2; CRF receptor 2; ERK1/2; extracellular signal-regulated kinase; GKAP; guanylate kinase-associa
The CXC chemokine receptors of fish: Insights into CXCR evolution in the vertebrates
Keywords: G پروتئین گیرنده کیناز; ACKR; atypical chemokine receptor; AGTR; angiotensin II receptor; AP-2; activated protein 2; CCR; CC chemokine receptors; CD; cluster of differentiation; CXC; CXC chemokine; CXCR; CXC chemokine receptor; CX3CR; CX3C receptor; ERK; extracellular regulated
Peptide substrates for G protein-coupled receptor kinase 2
Keywords: G پروتئین گیرنده کیناز; G protein-coupled receptor kinase; Peptide substrate; Phosphorylation; Cellular signal transduction pathway; Consensus sequence
Selective regulation of recombinantly expressed mGlu7 metabotropic glutamate receptors by G protein-coupled receptor kinases and arrestins
Keywords: G پروتئین گیرنده کیناز; mGlu7 receptors; GRK; Arrestins; MAP kinases; Jun kinases; Signaling regulation; GPCR; G protein-coupled receptor; mGlu; metabotropic glutamate receptor; GRK; G protein-coupled receptor kinase; FSK; forskolin; L-AP4; l-2-amino-4-phosphonobutanoate; MAPK;
Phosphodiesterase 4 interacts with the 5-HT4(b) receptor to regulate cAMP signaling
Keywords: G پروتئین گیرنده کیناز; 5-HT; 5-hydroxytryptamine; AKAP; A-kinase anchoring protein; DMSO; dimethyl sulfoxide; GRK; G protein-coupled receptor kinase; HEK293; human embryonic kidney cell line; IBMX; isobutylmethylxanthine; IP; immunoprecipitation; PDE; phosphodiesterase; PKA; pr
GRK-6 mediates FSH action synergistically enhanced by estrogen and the oocyte in rat granulosa cells
Keywords: G پروتئین گیرنده کیناز; DES; diethylstilbestrol; FSHR; follicle-stimulating hormone receptor; GRK; G protein-coupled receptor kinase; IBMX; 3-isobutyl-1-methylxanthine; P450arom; P450 aromatase; siRNA; small interfering RNA; StAR; steroidogenic acute regulatory protein; Estrogen
Epithelial G protein-coupled receptor kinases regulate the initial inflammatory response during mycobacterial infection
Keywords: G پروتئین گیرنده کیناز; GPCR; G protein-coupled receptors; GRK; G protein-coupled receptor kinase; LAM; lipoarabinomannan; PI-3K; phosphoinositide 3-kinases; ERK; extracellular signal-regulated kinase; Akt; serine/threonine protein kinase; COPD; chronic obstructive pulmonary dis
E-type prostanoid receptor 4 (EP4) in disease and therapy
Keywords: G پروتئین گیرنده کیناز; AMPK; AMP-activated protein kinase; cAMP; cyclic adenylyl monophosphate; CFTR; cystic fibrosis transmembrane conductance regulator; ClC; chloride channel; COX; cyclooxygenase; CREB; cAMP-response element-binding protein; DP; D-type prostanoid receptor; DS
Dysregulation of cannabinoid CB1 receptor and associated signaling networks in brains of cocaine addicts and cocaine-treated rodents
Keywords: G پروتئین گیرنده کیناز; Akt; protein kinase B; ANCOVA; analyses of covariance; CB; cannabinoid; CB2xP; mice overexpressing CB2 receptors; F1; cytosolic fraction; F2; membrane fraction; F3; nuclear fraction; F4; cytoskeletal fraction; FAAH; fatty acid amide hydrolase; GRK; G prot
cAMP: Novel concepts in compartmentalised signalling
Keywords: G پروتئین گیرنده کیناز; cAMP; cyclic adenosine 3â²,5â²-monophosphate; GPCR; G protein-coupled receptor; EC coupling; excitation-contraction coupling; FRET; Förster/fluorescence resonance energy transfer; CFP; cyan fluorescent protein; YFP; yellow fluorescent protein; AKAR;
Microglial GRK2: A novel regulator of transition from acute to chronic pain
Keywords: G پروتئین گیرنده کیناز; G protein-coupled receptor kinase; Hyperalgesia; Allodynia; Neuroinflammation; Pain;
GRK2 as a novel gene therapy target in heart failure
Keywords: G پروتئین گیرنده کیناز; β-adrenergic receptor; Heart failure; Gene therapy; G protein-coupled receptor kinase; βARKct; Neurohormonal feedback
Thromboxane-Induced Contractile Response of Human Coronary Arterioles Is Diminished After Cardioplegic Arrest
Keywords: G پروتئین گیرنده کیناز; 31; CABG; coronary artery bypass grafting; CaM PK; calmodulin phosphorylase kinase; CPB; cardiopulmonary bypass; CP/Rep; cardioplegia followed by reperfusion; DAPI; 4',6-diamidino-2-phenylindole; GRK; G protein-coupled receptor kinase; GSK; glycogen synth
Reduced expression of G protein-coupled receptor kinases in schizophrenia but not in schizoaffective disorder
Keywords: G پروتئین گیرنده کیناز; G protein-coupled receptor kinase; Arrestin; Schizophrenia; Schizoaffective disorder; Postmortem; Protein expression; RNAse protection assay; mRNA expression
Gαq allosterically activates and relieves autoinhibition of p63RhoGEF
Keywords: G پروتئین گیرنده کیناز; AF; Alexa Fluor 532; Dbs; Dbl's big sister; DH; Dbl homology; FCPIA; Flow cytometry protein interaction assay; FP; Fluorescence polarization; GFP; Green fluorescent protein; GRK; G protein-coupled receptor kinase; GPCR; G protein-coupled receptor; MFI; Me
Morphine-induced physiological and behavioral responses in mice lacking G protein-coupled receptor kinase 6
Keywords: G پروتئین گیرنده کیناز; Mu-opioid receptor; G protein-coupled receptor kinase; Morphine; Constipation; Locomotor activity; Sensitization
Role of the carboxyl terminal di-leucine in phosphorylation and internalization of C5a receptor
Keywords: G پروتئین گیرنده کیناز; C5aR; C5a receptor; GPCR; G protein-coupled receptor; GRK; G protein-coupled receptor kinase; ERK1/2; extracellular signal-regulated kinase 1/2; CHO; Chinese hamster ovary; EndoH; endoglycosidase H; AR; adrenergic receptor; Chemoattractant receptor; Endoc
Effects of crocin on reperfusion-induced oxidative/nitrative injury to cerebral microvessels after global cerebral ischemia
Keywords: G پروتئین گیرنده کیناز; Crocin; G protein-coupled receptor kinase; Nitric oxide synthase; Superoxide dismutase; Glutathione peroxidase
Targeting Myocardial β-Adrenergic Receptor Signaling and Calcium Cycling for Heart Failure Gene Therapy
Keywords: G پروتئین گیرنده کیناز; β-adrenergic receptors; G protein-coupled receptor kinase; S100A1; calcium regulation; gene therapy; heart failure
Homologous desensitization of signalling by the beta (β) isoform of the human thromboxane A2 receptor
Keywords: G پروتئین گیرنده کیناز; C-tail; carboxyl-terminal tail; [Ca2+]i; intracellular calcium; FBS; foetal bovine serum; GPCR; G protein-coupled receptor; GRK; G protein-coupled receptor kinase; HA; hemagglutinin; HEK; human embryonic kidney; IP; prostacyclin receptor; IP3; inositol 1,
Pathogenesis of levodopa-induced dyskinesia: focus on D1 and D3 dopamine receptors
Keywords: G پروتئین گیرنده کیناز; Parkinson disease; Dyskinesia; Supersensitivity; D1, D3, Cdk5, Arrestin; G Protein-coupled receptor kinase;
Activation of tyrosine kinase of EGFR induces Gβγ-dependent GRK-EGFR complex formation
Keywords: G پروتئین گیرنده کیناز; EGF; Epidermal growth factor; EGFR; EGF receptor; GPCR; G protein-coupled receptor; GRK; GPCR kinase; GRK2 DelN; GRK2 N-terminal deletion mutant; HA; hemagglutinin; HEK; human embryonic kidney; SDS-PAGE; polyacrylamide gel electrophoresis in the presenc
Peptide inhibitors of G protein-coupled receptor kinases
Keywords: G پروتئین گیرنده کیناز; Gβγ; βγ subunits of heterotrimeric GTP-binding proteins; GPCR; G protein-coupled receptor; GRK; G protein-coupled receptor kinase; IBMX; 3-isobutyl-1-methylxanthine; PKA; protein kinase A; PKC; protein kinase C; ROS; rod outer segments; G-protein-coup
Role of specific protein kinase C isoforms in modulation of β1- and β2-adrenergic receptors
Keywords: G پروتئین گیرنده کیناز; Signalling; G protein-coupled receptors; Desensitization; Protein kinase; α1BAR; α1B-adrenergic receptor; CA; constitutively active; CYP; cyanopindolol; βAR; β-adrenergic receptor; βARK; β-adrenergic receptor kinase; GPCR; G protein-coupled receptor
Activation and nuclear translocation of ERK1/2 by the formyl peptide receptor is regulated by G protein and is not dependent on β-arrestin translocation or receptor endocytosis
Keywords: G پروتئین گیرنده کیناز; GPCR; G protein-coupled receptor; ERK1/2; extracellular signal regulated kinases 1 and 2; FPR; N-formyl peptide receptor; GRK; G protein-coupled receptor kinase; fMLF; N-formyl-methionyl-leucyl-phenylalanine; CHO; Chinese hamster ovary; MAPK; mitogen-acti
l-DOPA reverses the MPTP-induced elevation of the arrestin2 and GRK6 expression and enhanced ERK activation in monkey brain
Keywords: G پروتئین گیرنده کیناز; Arrestin; G protein-coupled receptor kinase; Dyskinesia; Parkinson disease;
c-Src is involved in regulating signal transmission from PDGFβ receptor-GPCR(s) complexes in mammalian cells
Keywords: G پروتئین گیرنده کیناز; ASM; airway smooth muscle; CHO; Chinese hamster ovary; Con A; concanavalin A; Gi; inhibitory G protein; Giα; alpha sub-unit of Gi; Gab1; Grb-2 associated binder-1; GRK; G protein-coupled receptor kinase; GPCR; G protein-coupled receptor; Grb-2; growth fa
HIV chemokine receptor inhibitors as novel anti-HIV drugs
Keywords: G پروتئین گیرنده کیناز; AIDS; acquired immune deficiency syndrome; AOP; aminooxypentane; CI; clinical isolate; DC; dendritic cell; DC-SIGN; dendritic cell-specific ICAM-3-grabbing nonintegrin; FDA; Food and Drug Administration; FLIPR; fluorometric imaging plate reader; GCP; gran