Keywords: G پروتئین همراه با پروتئین; PI3K; phosphoinositide 3-kinase; MAPK; mitogen activated protein kinase; mTORC1; mTOR complex 1; GCN2; general control nonderepressible 2; ULK; UNC-5 like autophagy activating kinase; ATG; autophagy related gene; GPCR; G protein coupled receptor; UCPs; un
مقالات ISI G پروتئین همراه با پروتئین (ترجمه نشده)
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Keywords: G پروتئین همراه با پروتئین; Ach; acetylcholine; ADHD; attention-deficit hyperactivity disorder; BDNF; brain-derived neurotrophic factor; BEND; beta-endorphin; BFNA; beta-funaltrexamine; Ca(2+); calcium; CAMK; calmodulin-dependent protein kinase II; cAMP; cyclic adenosine monophospha
Keywords: G پروتئین همراه با پروتئین; AC; adenyl cyclase; AD; Alzheimer's disease; 2-AG; 2-arachidonoylglycerol; ABHD6; α,β hydrolase 6; AEA; arachidonylethanolamide/anandamide; ALS; amyotrophic lateral sclerosis; BBB; blood brain barrier; cAMP; cyclic adenosine monophosphate; CBD; cannabid
Keywords: G پروتئین همراه با پروتئین; Ach; acetylcholine (Ach); Ad; adrenaline; AKAP; A kinase anchoring protein; Ano1; anoctamin-1 Ca2 +-activated Clâ channel encoded by the ANO1 gene; α-SMA; α-smooth muscle actin; ASMCs; atypical smooth muscle cells; eYFP; enhanced-yellow fluorescent p
Keywords: G پروتئین همراه با پروتئین; Acc; acetyl-CoA carboxylase; ASM; acid sphingomyelinase; ATP; adenosine triphosphate; ATPase; adenosine triphosphatase; ATX; autotaxin; BMP; bis(monoacylglycero)phosphate; CDP; cytidine diphosphate; CL; cardiolipin; CNS; central nervous system; COPI; coat
Keywords: G پروتئین همراه با پروتئین; AA; arachidonic acid; ALP; alkaline phosphatase; ALX; G protein-coupled lipoxin A(4) receptor; AMP; adenosine monophosphate; BAT; brown adipose tissue; BMC; bone mineral content; BMD; bone mineral density; BMI; body mass index; CKD; chronic kidney disease
Keywords: G پروتئین همراه با پروتئین; Membrane domains; Very long chain fatty acid; SNAREs; DRM; detergent resistant membrane; GPCR; G protein coupled receptor; EGFR; epidermal growth factor receptor; GPI; glycosylphosphatidylinositol; TGN; trans Golgi network; VSVG; viral G glycoprotein of t
Keywords: G پروتئین همراه با پروتئین; Splicing factor; Disease; Chronic pain; Morphine; Synaptic transmission; G protein coupled receptor; Mu-opioid receptor;
Keywords: G پروتئین همراه با پروتئین; EGFR; Epidermal growth factor receptor; FITC; Fluorescein isothiocyanate; GPCR; G protein coupled receptor; IP3; Inositol-tris-phosphate; PIP2; Phosphatidyl-inositol-bis-phosphate; PLCγ; Phospholipase Cγ; PKA/C; Protein kinase A/C; PDGFR; Platelet-deriv
Keywords: G پروتئین همراه با پروتئین; Aβ; amyloid β; AADC; L-amino acid decarboxylase; ACC; Anterior cingulate cortex; AD; Alzheimer's disease; aMCI; Amnestic mild cognitive impairment; APP; Amyloid precursor protein; AR; Adrenergic receptor; ATMX; atomoxetine; BDNF; Brain-derived neurotrop
G protein coupled receptors can transduce signals through carboxy terminal and linker region phosphorylation of Smad transcription factors
Keywords: G پروتئین همراه با پروتئین; Transactivation; Smads; TGF-β; G protein coupled receptor; Phosphorylation;
Lysophosphatidylcholine and its phosphorothioate analogues potentiate insulin secretion via GPR40 (FFAR1), GPR55 and GPR119 receptors in a different manner
Keywords: G پروتئین همراه با پروتئین; Lysophosphatidylcholine (LPC); GPR40 (FFAR1); GPR55; GPR119; Insulin secretion; [Ca2+]i; intracellular calcium ions concentration; cAMP; cyclic AMP; GSIS; glucose-stimulated insulin secretion; GPCR; G protein coupled receptor; IBMX; 3-isobutyl-1-methylxan
Adrenergic receptor stimulation suppresses oxidative metabolism in isolated rat islets and Min6 cells
Keywords: G پروتئین همراه با پروتئین; Pancreatic Islet; β-cell metabolism; Proteomics; Adrenergic receptor; Insulin secretion; Oxidative phosphorylation; glucose stimulated insulin secretion; (GSIS); catecholamine; (CA); adrenergic receptor; (ADR); gene ontology; (GO); G protein coupled rece
PK2β ligand, a splice variant of prokineticin 2, is able to modulate and drive signaling through PKR1 receptor
Keywords: G پروتئین همراه با پروتئین; Prokineticin 2β; Prokineticin receptors; G protein coupled receptor; Yeast-STAT3; Thermal hyperalgesia; Tactile allodynia; GPCR; G Protein-Coupled Receptor; PK; Prokineticin; PKR; Prokineticin Receptor; PK2β; Prokineticin 2β; ERK; Extracellular signal-
Bifunctional ligands of the bradykinin B2 and B1 receptors: An exercise in peptide hormone plasticity
Keywords: G پروتئین همراه با پروتئین; ACE; angiotensin converting enzyme; ε-ACA; ε-aminocaprolyl; APEX2; engineered soya bean peroxidase; Arg-CP; arginine carboxypeptidase; B1R; B1 receptor; B2R; B2 receptor; B2R-GFP; rabbit B2 receptor fused to green fluorescent protein; BK; bradykinin; CF
Expression of the adhesion G protein-coupled receptor A2 (adgra2) during Xenopus laevis development
Keywords: G پروتئین همراه با پروتئین; Adgra2; Gpr124; TEM5; Expression; Synteny; Xenopus laevis; a; animal; A; anterior; Adgr; adhesion G protein coupled receptor; Adgra2; adhesion G protein-coupled receptor A2; BA; branchial arches; BC; blastocoel; BL; blastopore lip; BP; blastopore; CG; cem
The role of CXCL12 in tumor microenvironment
Keywords: G پروتئین همراه با پروتئین; CXCL12; C-X-C motif chemokine ligand 12; TME; tumor microenvironment; GPCR; G protein coupled receptor; CXCR4; chemokine receptor 4; CXCR7; chemokine receptor 7; VCAM-1; vascular cell adhesion molecule-1; VEGF; vascular endothelial growth factor; MMP; mat
Differential distribution and function of GABABRs in somato-dendritic and axonal compartments of principal cells and interneurons in cortical circuits
Keywords: G پروتئین همراه با پروتئین; Dendritic inhibition; Presynaptic inhibition; Network activity; Electron microscopy; Synaptic plasticity; Ion channels; BC; basket cell; CA; cornu ammonis; CaMKII; Ca2+/calmodulin-dependent protein kinase II; cAMP; cyclic adenosine monophosphate; Cav chan
Label-free cell signaling pathway deconvolution of angiotensin type 1 receptor reveals time-resolved G-protein activity and distinct AngII and AngIIIIV responses
Keywords: G پروتئین همراه با پروتئین; AngII; Angiotensin II; AT1R; angiotensin type 1 receptor; βarr; β-Arrestin; DMR; dynamic mass redistribution; ERK; extracellular signal-regulated kinase; GPCR; G protein coupled receptor; PTX; pertussis toxin; PI3K; phosphoinoside 3-kinase; rVSMC; rat v
Characterization of signal bias at the GLP-1 receptor induced by backbone modification of GLP-1
Keywords: G پروتئین همراه با پروتئین; Glucagon-like peptide-1 receptor; G protein coupled receptor; Biased agonism; Cell signaling; Peptides;
Gq and Gs signaling acting in synergy to control GLP-1 secretion
Keywords: G پروتئین همراه با پروتئین; GPCR; GLP-1 secretion; Pharmacological synergy; Incretins; G protein signaling; 2-MAG; 2-monoacylglycerol; BB2; bombesin 2 receptor; CTX; cholera toxin; GLP-1; glucagon-like peptide 1; GIP; gastrointestinal peptide; GPCR; G protein coupled receptor; LCFA;
Stretch-induced actomyosin contraction in epithelial tubes: Mechanotransduction pathways for tubular homeostasis
Keywords: G پروتئین همراه با پروتئین; ATP; adenosine triphosphate; DAG; diacylglycerol; ECM; extracellular matrix; FAK; focal adhesion kinase; GAP; GTPase activating protein; GDI; guanine dissociation factor; GEF; guanine nucleotide exchange factor; GPCR; G protein coupled receptor; HUVEC; Hu
A crosstalk between muscarinic and CRF2 receptors regulates cellular adhesion properties of human colon cancer cells
Keywords: G پروتئین همراه با پروتئین; AJ; adherens junctions; ctn; catenin; CRC; colorectal cancer; CRF2; corticotrophin releasing factor receptor 2; ECM; extracellular matrix; EGFR; epidermal growth factor receptor; EMT; epithelial-mesenchymal transition; FAK; focal adhesion kinase; GPRC; G
Spatial encryption of G protein-coupled receptor signaling in endosomes; Mechanisms and applications
Keywords: G پروتئین همراه با پروتئین; AKT (PKB); protein kinase B; AP2; adaptor protein 2; APPL1; adaptor protein containing PH domain, PTB domain, and Leucine zipper motif; ARRDC; arresting domain containing; Î1AR; B2AR, beta-adrenergic receptor 1 or 2; CCP; clathrin coated pit; CXCR4; chem
Optogenetics - Bringing light into the darkness of mammalian signal transduction
Keywords: G پروتئین همراه با پروتئین; AsLOV2; Avena sativa light-oxygen-voltage domain 2; ChR2; Channelrhodopsin-2; CIB1; Chryptochrome-interacting basic helix-loop-helix 1; CIBN; N-terminus of CIB1; COP1; Constitutive photomorphogenesis protein 1; CPH1; Cyanobacterial phytochrome 1; CRY2; Cr
The metalloproteinase ADAM10: A useful therapeutic target?
Keywords: G پروتئین همراه با پروتئین; APL; Acute Promyelocytic Leukemia; ADAM; A Disintegrin And Metalloproteinase; AP2; Adaptor Protein-2; AD; Alzheimer's Disease; Aβ; Amyloid beta; APP; Amyloid Precursor Protein; ACE; Angiotensin Converting Enzyme; APRIL; A Proliferation-Inducing Ligand; B
Stabilizing effects of G protein on the active conformation of adenosine A1 receptor differ depending on G protein type
Keywords: G پروتئین همراه با پروتئین; G protein coupled receptor; Adenosine A1 receptor; Förster resonance energy transfer (FRET); Conformational change; G protein coupling;
Delineating biased ligand efficacy at 7TM receptors from an experimental perspective
Keywords: G پروتئین همراه با پروتئین; G protein coupled receptor; Functional selectivity; Bias factor; Resonance energy transfert; β-arrestin; II messengers
ADAMs family and relatives in cardiovascular physiology and pathology
Keywords: G پروتئین همراه با پروتئین; ADAM; A disintegrin and metalloproteinase; ADAM-TS; ADAM with thrombospondin domains; APP; amyloid precursor protein; APPsα; α-secretase-released N-terminal APP domain; C-domain; cysteine-rich domain; COMP; cartilage oligomeric matrix protein; DCM; dila
Gia/Mthl5 is an aorta specific GPCR required for Drosophila heart tube morphology and normal pericardial cell positioning
Keywords: G پروتئین همراه با پروتئین; Gia; Methuselah-like; Drosophila; Heart development; G protein coupled receptor;
Cell migration towards CXCL12 in leukemic cells compared to breast cancer cells
Keywords: G پروتئین همراه با پروتئین; DMEM; Dulbecco's Modified Eagle's Medium; EDTA; ethylenediaminetetraacetic acid; FCS; foetal calf serum; GPCR; G protein coupled receptor; mAB; monoclonal antibody; n.s.; non-significant; PBS; phosphate buffered saline; PKC; Protein Kinase c; S.E.M.; stan
Cardiac action of the first G protein biased small molecule apelin agonist
Keywords: G پروتئین همراه با پروتئین; Apelin; Biased agonism; G protein coupled receptor; Cardiovascular; In vivo;
FRET biosensors reveal AKAP-mediated shaping of subcellular PKA activity and a novel mode of Ca2Â +/PKA crosstalk
Keywords: G پروتئین همراه با پروتئین; AKAP; A-Kinase Anchoring Protein; AKAR3; A-Kinase activity reporter 3; β2AR; β2-adrenergic receptor; [Ca2 +]i; intracellular calcium concentration; CaM; calcium-calmodulin; cAMP; cyclic adenosine monophosphate; CB4; calmodulin binding domain 4; CFP; cy
Cannabinoid receptor interacting protein (CRIP1a) attenuates CB1R signaling in neuronal cells
Keywords: G پروتئین همراه با پروتئین; 2-AG; 2-arachidonoylglycerol; BSA; bovine serum albumin; CB1; cannabinoid receptor; CP55940; (â)-cis-3-[2-Hydroxy-4-(1,1-dimethylÂheptyl)phenyl]-trans-4-(3-hydroxypropyl)cyclohexanol; CRIP1a; Cannabinoid Receptor Interacting Protein 1a; DAGL; diacylgly
Investigation of the role of βarrestin2 in kappa opioid receptor modulation in a mouse model of pruritus
Keywords: G پروتئین همراه با پروتئین; Pruritus; Kappa opioid receptor; Biased ligand; Mouse models of itch; U50,488H; KOR antagonist; βarr2-KO; βarrestin2 knockout; CP; chloroquine phosphate; CPA; conditioned place aversion; DMSO; dimethyl sulfoxide; 5â²-GNTI; 5â²-guanidinonaltrindole; GP
Characterization of kappa opioid receptor mediated, dynorphin-stimulated [35S]GTPγS binding in mouse striatum for the evaluation of selective KOR ligands in an endogenous setting
Keywords: G پروتئین همراه با پروتئین; Dynorphin; Kappa opioid receptor; [35S]GTPγS binding; Mouse striatum; Selectivity; Drug discovery; KOR antagonist; CTOP; D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2; DAMGO; [D-Ala2, NMe-Phe4, Gly-ol5]-enkephalin; Dyn; dynorphin; DOR; delta opioid receptor; [
The identification of GPR3 inverse agonist AF64394; The first small molecule inhibitor of GPR3 receptor function
Keywords: G پروتئین همراه با پروتئین; GPR3; GPR6; GPR12; G protein coupled receptor; Orphan receptor; Inverse agonist; AF64394
Membrane-associated cargo recycling by tubule-based endosomal sorting
Keywords: G پروتئین همراه با پروتئین; BAR; Bin/Amphiphysin/Rvs; ERC; endosome recycling compartment; FERM; 4.1/ezrin/radixin/moesin; GPCR; G protein coupled receptor; PDZ; PSD-95/Dlg1/Zo-1; PX; phox homology; SNX; sorting nexin; TEN; tubular endosomal network; TfR; transferrin receptor; TGN;
A tagged parathyroid hormone derivative as a carrier of antibody cargoes transported by the G protein coupled PTH1 receptor
Keywords: G پروتئین همراه با پروتئین; Parathyroid hormone; PTH1 receptor; Osteoblast; Receptor-mediated transport; CM; conditioned medium; mCherry; mCherry fluorescent protein; EGFP; enhanced green fluorescent protein; GPCR; G protein coupled receptor; HRP; horseradish peroxidase; PTH; parath
Activation of PPARβ/δ protects pancreatic β cells from palmitate-induced apoptosis by upregulating the expression of GLP-1 receptor
Keywords: G پروتئین همراه با پروتئین; PPARβ/δ; peroxisome proliferator-activated receptor β/δ; GLP-1R; glucagon-like peptide-1 receptor; GW; GW501516; PA; palmitate; qPCR; quantitative polymerase chain reaction; SREBP-1c; sterol regulatory element binding protein-1c; GSIS; glucose-stimula
Sphingosine-1-phosphate (S1P) displays sustained S1P1 receptor agonism and signaling through S1P lyase-dependent receptor recycling
Keywords: G پروتئین همراه با پروتئین; BSA; bovine serum albumin; CHO; Chinese hamster ovary; CRC; concentration-response curve; EC50; half maximimal excitatory concentration; Emax; maximal efficacy versus a defined control; FBS; fetal bovine serum; GPCR; G protein coupled receptor; GRK; GPC
“Are melanocortin receptors constitutively active in vivo?”
Keywords: G پروتئین همراه با پروتئین; G protein coupled receptor; POMC; Melanocortin; Pigmentation; Energy homeostasis;
Mechanism of dopamine D2 receptor-induced Ca2Â + release in PC-12 cells
Keywords: G پروتئین همراه با پروتئین; DR; dopamine receptor; PLC; phospholipase C; CaMKII; calmodulin kinase II; IP3; inositol 1,4,5-trisphosphate; IP3R; inositol 1,4,5-trisphospate receptor; PKA; protein kinase A; GPCR; G protein coupled receptor; DMSO; dimethylsulfoxid; EC50; 50% effective
Differential regulation of chemotaxis: Role of Gβγ in chemokine receptor-induced cell migration
Keywords: G پروتئین همراه با پروتئین; CHO; Chinese hamster ovary; CCL3; Chemokine ligand 3; CCR5; Chemokine receptor 5; DMEM; Dulbecco's modified Eagle's medium; EDTA; Ethylenediaminetetraacetic acid; ERK; Extracellular signal-regulated kinases; FCS; Foetal calf serum; GPCR; G protein coupled
Conjugated linoleic acid-induced apoptosis in mouse mammary tumor cells is mediated by both G protein coupled receptor-dependent activation of the AMP-activated protein kinase pathway and by oxidative stress
Keywords: G پروتئین همراه با پروتئین; AMPK; AMP-activated protein kinase; 2-APB or APB; 2-aminoethyl diphenylborinate; BAPTA-AM; 1,2-bis(o-aminophenoxy)-ethane-N,N,-N',N'-tetraacetic acid tetraacetoxy-methyl ester; CaMKKα; calcium/calmodulin-dependent protein kinase kinase α; CLA; conjugate
The interaction between mGluR1 and the calcium channel CaV2.1 preserves coupling in the presence of long Homer proteins
Keywords: G پروتئین همراه با پروتئین; G protein coupled receptor; Calcium channel; Sympathetic neuron; Pharmacology; mGluR; Metabotropic glutamate receptor; SCG; Superior cervical ganglion; Glu; l-Glutamate;
Rit subfamily small GTPases: Regulators in neuronal differentiation and survival
Keywords: G پروتئین همراه با پروتئین; CA; constitutively active; cAMP; cyclic adenosine monophosphate; CaM; calmodulin; CCI; controlled cortical impact; CREB; cAMP response element binding protein; CRIB; Cdc42/Rac interactive binding; DA; dopamine; DAT; dopamine transporter; DN; dominant nega
Caveolae-dependent internalization and homologous desensitization of VIP/PACAP receptor, VPAC2, in gastrointestinal smooth muscle
Keywords: G پروتئین همراه با پروتئین; Caveolin-1; Endocytosis; G protein coupled receptor; GRK2;
Gastrointestinal hormones stimulate growth of Foregut Neuroendocrine Tumors by transactivating the EGF receptor
Keywords: G پروتئین همراه با پروتئین; Bn; bombesin; EGFR; epidermal growth factor receptor; GI; gastrointestinal; GPCR; G protein coupled receptor; HNSCC; head and neck squamous cell cancers; MMP; matrix metalloproteinases; NETs; neuroendocrine tumors; NT; neurotensin; PETs; pancreatic endocr
CaV1.2 signaling complexes in the heart
Keywords: G پروتئین همراه با پروتئین; LTCC; L-type Ca2 + channel; βAR; β-adrenergic receptor; EPR; E type prostaglandin receptor; RyR2; type 2 ryanodine receptor; AC; adenylyl cyclase; PDE; phosphodiesterase; PP; protein phosphatase; AKAP; A kinase anchoring protein; PKA; protein kinase A;