دانلود مقالات ISI درباره Gpcr + ترجمه فارسی

PACAP protects against TNFα-induced cell death in olfactory epithelium and olfactory placodal cell lines

Keywords: AA; amino acid; AC; adenylate cyclase; BSA; bovine serum albumin; cAMP; cyclic adenosine monophosphate; CNS; central nervous system; dNTP; deoxynucleotide triphosphate; dT; deoxythymidine; EC1; first extracellular domain of PAC1R sequence; FBS; fetal bovi

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Negative regulation of Ca2+ influx during P2Y2 purinergic receptor activation is mediated by Gβγ-subunits

Keywords: GPCR; heptahelical G protein-coupled receptor; βARK; β-adrenergic receptor kinase; Gα; α-subunit of G protein; Gβγ; βγ-subunits of the G protein; Ad-MX17; adenovirus that contains only virus backbone; Ad-EF1-wtGαq; adenovirus expressing α-subuni

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

NMR studies of new arginine vasopressin analogs modified with α-2-indanylglycine enantiomers at position 2 bound to sodium dodecyl sulfate micelles

Keywords: AVP; arginine vasopressin; GPCR; G-protein coupled receptor; Igl; α-2-indanylglycine; Mpa; 3-mercaptopropionic acid; OT; oxytocin; SDS; sodium dodecyl sulfate; α-2-Indanylglycine; Vasopressin; SDS micelle; NMR spectroscopy; Molecular modeling;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Genome-wide prediction of G protein-coupled receptors in Verticillium spp.

Keywords: Fungi; Genome; GPCR; PTM1-like GPCRs; Verticillium;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Temperature dependent photolabeling of the human angiotensin II type 1 receptor reveals insights into its conformational landscape and its activation mechanism

Keywords: GPCR; Photolabeling; Molecular modeling; Constitutive activity; Angiotensin II

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Lysophosphatidic acid induces upregulation of Mcl-1 and protects apoptosis in a PTX-dependent manner in H19-7 cells

Keywords: LPA; lysophosphatidic acid; NPC; neuronal progenitor cell; Mcl; myeloid cell leukemia; GSK-3; glycogen synthase kinase 3; PTX; pertussis toxin; FGF; fibroblast growth factor; S1P; sphingosine 1-phosphate; GPCR; G-protein coupled receptor; E; embryonic day

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

RGS14 is a multifunctional scaffold that integrates G protein and Ras/Raf MAPkinase signalling pathways

Keywords: RGS; regulators of G protein signalling; RBD; Ras/Rap binding domain; GPCR; G protein coupled receptor; MAPkinase; Mitogen-activated protein kinases; GPR/GoLoco (GL); G protein regulatory motif; GEF; guanine exchange factor; GDI; guanine nucleotide dissoc

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Dexamethasone enhances the norepinephrine-induced ERK/MAPK intracellular pathway possibly via dysregulation of the α2-adrenergic receptor: Implications for antidepressant drug mechanism of action

Keywords: 5-HT; serotonin; AP-1; activator protein 1; AR; adrenergic receptor; BDNF; brain derived neurotrophic factor; DEX; dexamethasone; FCS; fetal calf serum; GC; glucocorticoid; GPCR; G-protein-coupled receptor; GR; glucocorticoid receptor; GRK; G-protein rece

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Clinical resistance to vicriviroc through adaptive V3 loop mutations in HIV-1 subtype D gp120 that alter interactions with the N-terminus and ECL2 of CCR5

Keywords: HIV-1; Virus entry; CCR5 co-receptor; GPCR; CCR5 antagonists; Vicriviroc; gp120 resistance mutations

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Development of tolerance in D3 dopamine receptor signaling is accompanied by distinct changes in receptor conformation

Keywords: Desensitization; Drd3; Modeling; Biotinylation; Signaling; GPCR

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Expression of G protein-coupled receptor 30 in the spinal somatosensory system

Keywords: ERs; estrogen receptors; GPR30; G protein-coupled receptor 30; DRG; dorsal root ganglion; ER; estrogen receptor; GPCR; G protein-coupled receptor: OVX, ovariectomy; E2; estradiol; IHC; immunohistochemistry; ir; immunoreactivity; C; cervical; T; thoracic;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

Histamine signalling in Schistosoma mansoni: Immunolocalisation and characterisation of a new histamine-responsive receptor (SmGPR-2)

Keywords: Schistosoma mansoni; Histamine; Biogenic amines; GPCR; Receptor; Platyhelminthes; Neurotransmitter; Confocal immunofluorescence

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

NG-Acyl-argininamides as NPY Y1 receptor antagonists: Influence of structurally diverse acyl substituents on stability and affinity

Keywords: Acyl guanidines; NPY; BIBP 3226; GPCR

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

Prenylation-deficient G protein gamma subunits disrupt GPCR signaling in the zebrafish

Keywords: PGC; Migration; Zebrafish; GPCR; Prenylation; Gamma; Betagamma;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

Modulation of G-protein coupled receptor sample quality by modified cell-free expression protocols: A case study of the human endothelin A receptor

Keywords: B35; Brij-35; B58; Brij-58; B78; Brij-78; B98; Brij-98; CD; circular dichroism; CF; cell-free; CHAPS; 3-[(3-cholamidopropyl) dimethylammonio]-1-propansulphonat; CHS; cholesteryl hemisuccinate tris salt; CMC; critical micellar concentration; CV; column vol

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

Affinity of aporphines for the human 5-HT2A receptor: Insights from homology modeling and molecular docking studies

Keywords: Nantenine; Aporphine; Serotonin; MDMA; 5-HT2A; 5-HT; 5-hydroxytryptamine, serotonin; AcOH; acetic acid; Boc; tert-butoxycarbonyl; BLAST; Basic Local Alignment Search Tool; BRho; bovine rhodopsin; CDI; 1,1′-carbonyldiimidazole; D; aspartic acid; DCM; dic

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2010 سفارش ترجمه

Identification of the early VIP-regulated transcriptome and its associated, interactome in resting and activated murine CD4 T cells

Keywords: GPCR; G-protein coupled receptor; VIP; vasoactive intestinal peptide; VPAC1; vasoactive intestinal peptide receptor 1; CNS; central nervous system; PP; Peyer's patches; SAM; Significance Analysis of Microarrays; IPA; Ingenuity Pathway Analysis; Treg; regu

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2010 سفارش ترجمه

Membrane receptors: Structure and function of the relaxin family peptide receptors

Keywords: GPCR; Relaxin; INSL3; RXFP; Peptide

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2010 سفارش ترجمه

Activation of human mast cells through the platelet-activating factor receptor

Keywords: Anaphylaxis; histamine; human lung mast cells; human peripheral blood-derived mast cells; human skin mast cells; platelet-activating factor receptor; GAPDH; Glyceraldehyde-3-phosphate dehydrogenase; GPCR; G protein-coupled receptor; IMDM; Iscove modif

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2010 سفارش ترجمه

Cellular functions of Transient Receptor Potential channels

Keywords: TRP; transient receptor potential; ADPR; ADP ribose; ROS; reactive oxygen/nitrogen species; PARP; poly ADP-ribose polymerase; SOC; store operated channel; SOCE; store operated calcium entry; CCE; capacitative calcium entry; TNF-α; tumor necrosis factor-Î

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2010 سفارش ترجمه

Reviews in Basic and Clinical GastroenterologyLeucine-Rich Repeat-Containing G-Protein-Coupled Receptors as Markers of Adult Stem Cells

Keywords: Lgr5; Lgr6; Stem Cell Marker; GPCR; Ascl2; Achaete scute-like 2; CBC; crypt base columnar; FSH; follicle-stimulating hormone; GFP; green fluorescent protein; Lgr; leucine-rich repeat-containing, G-protein-coupled receptor; LH; leutinizing hormone; 7

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2010 سفارش ترجمه

Neutralizing endogenous chemokines with small molecules

Keywords: BSA; Bovine serum albumin; DARC; Duffy antigen receptor for chemokines; GAG; Glycosaminoglycans; GPCR; G-protein-coupled receptor; IL; Interleukin; LPS; Lipopolysaccharide; MS; Multiple sclerosis; Chemokines; Cytokines; GPCRs; Decoy receptors; Neutralizin

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2010 سفارش ترجمه

Structure and function of G protein-coupled receptors using NMR spectroscopy

Keywords: Membrane proteins; Magic angle spinning; Structure; CL; cytoplasmic loop; cryo-EM; cryogenic electron microscopy; C-terminus; carboxy terminus; DARR; dipolar-assisted rotational resonance; DDM; dodecyl-β-d-maltoside; DNA; deoxyribonucleic acid; DNP; dyna

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2010 سفارش ترجمه

Sf9 cells: A versatile model system to investigate the pharmacological properties of G protein-coupled receptors

Keywords: Sf9 insect cells; GPCR; G-protein; Functional reconstitution; Constitutive activity; Protein expression[125I]APT, 125I-labeled iodoaminopotentidine; [32P]AAGTP, [32P]P3(4-azidoanilido)-P1-5′-GTP; 5-HTxR, serotonine receptor subtypes; AC, adenylyl cyclase

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2010 سفارش ترجمه

From the cell to the clinic: A comparative review of the partial D2/D3 receptor agonist and α2-adrenoceptor antagonist, piribedil, in the treatment of Parkinson's disease

Keywords: Ropinirole; Pramipexole; Pergolide; Antiparkinson; α2-Adrenoceptor; D2 receptor; D3 receptor; ACh; acetylcholine; Akt; atypical kinase; AR; adrenoceptor; BDNF; brain derived neurotrophic factor; COMT; catechol-Ortho-methyltransferase; DA; dopamine; ERK;

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2010 سفارش ترجمه

Synthesis and SAR studies of trisubstituted purinones as potent and selective adenosine A2A receptor antagonists

Keywords: Adenosine; GPCR; Purinone; SAR; Parkinson’s disease

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Fluorinated non-imidazole histamine H3 receptor antagonists

Keywords: Histamine; H3; Receptor; GPCR; Medicinal chemistry; PET; CNS; Neurotransmitter

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Rhodopsin: Structure, signal transduction and oligomerisation

Keywords: Rhodopsin; GPCR; Three-dimensional structure; Oligomerisation; Signal transduction;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Fluorinated 9H-xanthene-9-carboxylic acid oxazol-2-yl-amides as potent, orally available mGlu1 receptor enhancers

Keywords: Metabotropic glutamate receptor 1; mGluR1; GPCR; Positive allosteric modulator; PAM; Enhancer

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Synthesis of 2-amino-5-benzoyl-4-(2-furyl)thiazoles as adenosine A2A receptor antagonists

Keywords: Adenosine; GPCR; Aminothiazole; Parkinson’s disease; Combinatorial chemistry; ECLiPSTM

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

New intercellular lipid mediators and their GPCRs: An update

Keywords: Lipid mediator; GPCR; Lipid; Lysophospholipid; Fatty acid; Bile acid

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Structural models for the complex of chemotaxis inhibitory protein of Staphylococcus aureus with the C5a receptor

Keywords: GPCRs; C5a receptor; Chemotaxis inhibitory protein; Molecular modeling; GPCR; G-protein-coupled receptor; C5a; anaphylotoxin C5a; C5aR; C5a receptor; CHIPS; chemotaxis inhibitory protein of Staphylococcus aureus;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Calcium-sensing receptor: A high-affinity presynaptic target for aminoglycoside-induced weakness

Keywords: Nerve terminal; Calcium-sensing receptor; VACC; GPCR; Aminoglycoside; Myastheia gravis

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2009 سفارش ترجمه

Increased plasma membrane expression of human follicle-stimulating hormone receptor by a small molecule thienopyr(im)idine

Keywords: FSH receptor; Pharmacoperone; Peptidomimetic; Small molecule; GPCR; Receptor; Therapeutics;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Spare interactions of highly potent [Arg14,Lys15]nociceptin for cooperative induction of ORL1 receptor activation

Keywords: EL2; The second extracellular loop; GPCR; G protein-coupled receptor; ORL1; Opioid receptor-like receptor 1; TM5; The fifth transmembrane domain; Binding site; Nociceptin; Receptor activation; Site-directed mutagenesis; Synergistic effect;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Optimization of a series of quinazolinone-derived antagonists of CXCR3

Keywords: CXCR3; IP10; ITAC; MIG; CXCL9; CXCL10; CXCL11; Chemokine receptor; GPCR; Antagonist; Quinazolinone; SAR

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Novel sulfone-containing di- and trisubstituted cyclohexanes as potent CC chemokine receptor 2 (CCR2) antagonists

Keywords: CCR2; CCR2 antagonist; Chemokine; GPCR

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Efficient silkworm expression of human GPCR (nociceptin receptor) by a Bombyx mori bacmid DNA system

Keywords: Baculovirus; Silkworm; GPCR; Bacmid; Membrane protein; Protein expression; BmNPV;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Tetrahydroquinoline derivatives as CRTH2 antagonists

Keywords: CRTH2; PGD2; Antagonists; GPCR; Allergic diseases; Tetrahydroquinoline; SAR; Lead optimization;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Electrical impedance measurements predict cellular transformation

Keywords: Impedance; Transformation; CXCR2; Cancer; ECIS; GPCR;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Identification of 2-aminobenzimidazoles as potent melanin-concentrating hormone 1-receptor (MCH1R) antagonists

Keywords: MCHIR-antagonist; Melanin-concentrating hormone; Obesity; GPCR

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

GISP increases neurotransmitter receptor stability by down-regulating ESCRT-mediated lysosomal degradation

Keywords: GISP; TSG101; AKAP; EGF; Receptor trafficking; Degradation; ESCRT; GPCR;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Prostaglandin EP3 receptor superactivates adenylyl cyclase via the Gq/PLC/Ca2+ pathway in a lipid raft-dependent manner

Keywords: Raft; Caveolin; Signal cross-talk; Prostanoid; GPCR

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Discovery and optimization of CRTH2 and DP dual antagonists

Keywords: CRTH2; DP; Antagonists; GPCR; Asthma; PGD2

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Phosphatidic acid potentiates Gαq stimulation of phospholipase C-β1 signaling

Keywords: Gαq; GPCR; Phosphatidic acid; Phospholipase C-β; Phospholipase DDGK, diacylglycerol kinase; GAP, GTPase activating protein; GPCR, G protein coupled receptor; PA, phosphatidic acid; PLC-β, phospholipase C-β; PLD, phospholipase D; PMA, 4β-phorbol 12-myrista

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Discovery of novel non-peptidic β-alanine piperazine amide derivatives and their optimization to achiral, easily accessible, potent and selective somatostatin sst1 receptor antagonists

Keywords: Somatostatin; GPCR; Somatostatin sst1 receptor; Selective sst1 receptor antagonists; Achiral; Non-peptidic somatostatin analogs

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Screening the V2R-type putative odorant receptor gene repertoire in bitterling Tanakia lanceolata

Keywords: OR; olfactory receptor; V1R; vomeronasal receptor, family 1; V2R; vomeronasal receptor, family 2; CaSR; calcium sensing receptor; GPCR; G protein-coupled receptor; TM; transmembrane; Odorant receptor; Vomeronasal receptor; Multigene family; Teleost fish;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Exploring a pocket for polycycloaliphatic groups in the CXCR3 receptor with the aid of a modular synthetic strategy

Keywords: CXCR3; Reductive amination; GPCR; Polycycloaliphatic

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Phosphatidic acid regulates signal output by G protein coupled receptors through direct interaction with phospholipase C-β1

Keywords: DGK, diacylglycerol kinase; GAP, GTPase activating protein; PA, phosphatidic acid; PLC-β, phospholipase C β; PLD, phospholipase DPhosphatidic acid; Phospholipase C-β; Gαq; GPCR; Phospholipase D; Diacylglycerol kinase

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

A novel GalR2-specific peptide agonist

Keywords: Galanin; GALP; GPCR; Agonist; GalR; Chimeric peptide; Inositol phosphate production; Receptor specificity

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه