دانلود مقالات ISI درباره Gpcr + ترجمه فارسی

Multiple motifs regulate the trafficking of GABAB receptors at distinct checkpoints within the secretory pathway

Keywords: GABAB; γ-aminobutyric acid type B receptors; GPCR; G-protein-coupled receptors; ER; endoplasmic reticulum; LL; di-leucine; GEF; guanine-nucleotide-exchange factor; ARF; ADP-ribosylation factor; TGN; trans-Golgi network; PH; pleckstrin homology domain;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

The role of sphingosine-1-phosphate in smooth muscle contraction

Keywords: ASM; airway smooth muscle; [Ca2+]i; intracellular calcium concentration; CNP; C-type natriuretic peptide; CHO; Chinese hamster ovary; DAG; diacylglycerol; dihydro-S1P; sphinganine-1-phosphate; eNOS; endothelial nitric oxide synthase; ER; endoplasmic retic

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Role of specific protein kinase C isoforms in modulation of β1- and β2-adrenergic receptors

Keywords: Signalling; G protein-coupled receptors; Desensitization; Protein kinase; α1BAR; α1B-adrenergic receptor; CA; constitutively active; CYP; cyanopindolol; βAR; β-adrenergic receptor; βARK; β-adrenergic receptor kinase; GPCR; G protein-coupled receptor

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Agonist-induced up-regulation of human somatostatin receptor type 1 is regulated by β-arrestin-1 and requires an essential serine residue in the receptor C-tail

Keywords: AC; adenylyl cyclase; CaM; calcium calmodulin; CHO-KI; Chinese hamster ovary cell line; FBS; fetal bovine serum; GPCR; G protein-coupled receptor; GRK; GPCR kinase; hSSTR; human somatostatin receptor; MAPK; mitogen activated protein kinase; PKA; protein k

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Interaction of transducin-α with LGN, a G-protein modulator expressed in photoreceptor cells

Keywords: GPCR; G-protein-coupled receptor; GPR motif; G-protein regulatory motif; LGN; GPR protein termed based on the presence of Leu-Gly-Asn repeats (gene name and symbol: G-protein signaling modulator 2, GPSM2); AGS3; activator of G-protein signaling 3 (gen

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Expression of G protein coupled receptors in a cell-free translational system using detergents and thioredoxin-fusion vectors

Keywords: Cell-free protein synthesis; Detergent; GPCR; Thioredoxin;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

New methodologies for measuring protein interactions in vivo and in vitro

Keywords: AFM; atomic force microscopy/microscope; BRET; bioluminescence resonance energy transfer; DBD; DNA-binding domain; FRET; fluorescence resonance energy transfer; GFP; green fluorescent protein; GPCR; G-protein-coupled receptor; PCA; protein fragment comple

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Valine-286 residue in the third intracellular loop of the cholecystokinin 2 receptor exerts a pivotal role in cholecystokinin 2 receptor mediated intracellular signal transduction in human colon cancer cells

Keywords: cAMP; cyclic AMP; CCK2R; cholecystokinin 2 receptor; ERK; extracellular signal-regulated kinase; FAK; focal adhesion kinase; G-17; mature amidated gastrin; GPCR; G protein-coupled receptor; IP3; inositol 1,4,5-trisphosphate; MAPK; mitogen-activated protei

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Proton-sensing and lysolipid-sensitive G-protein-coupled receptors: A novel type of multi-functional receptors

Keywords: OGR1; ovarian cancer G-protein-coupled receptor 1; TDAG8; T-cell death-associated gene 8; GPCR; G-protein-coupled receptor; SPC; sphingosylphosphorylcholine; LPC; lysophosphatidylcholine; PTX; pertussis toxin; [Ca2+]i; intracellular calcium concentration;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Solubilization, stabilization, and purification of chemokine receptors using biosensor technology

Keywords: Biacore; Surface plasmon resonance; GPCR; Membrane receptor; HIV;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Inhibitors of actin polymerisation stimulate arachidonic acid release and 5-lipoxygenase activation by upregulation of Ca2+ mobilisation in polymorphonuclear leukocytes involving Src family kinases

Keywords: AA; arachidonic acid; CLP; coactosin-like protein; Cyt; cytochalasin; cPLA2; cytosolic phospholipase A2; 5-LO; 5-lipoxygenase; fMLP; N-formyl-methionyl-leucyl-phenylalanine; ERK; extracellular signal-regulated kinase; GPCR; G protein-coupled receptor; LB;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Validation of a histamine H3 receptor model through structure–activity relationships for classical H3 antagonists

Keywords: Histamine H3 receptor; Histamine antagonists; GPCR; Docking

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Immunohistochemical distribution of MIZIP and its co-expression with the Melanin-concentrating hormone receptor 1 in the adult rodent brain

Keywords: Cellular and Molecular Biology; Gene structure and function; GPCR; G-protein-coupled receptor; HEK; human embryonic kidney; MCH; Melanin-concentrating hormone; MCHR1; MCH-receptor 1; MIZIP; MCHR1 interacting zinc-finger protein; MYND; zinc-finger domain o

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

The role of sphingosine and ceramide kinases in inflammatory responses

Keywords: AA; arachidonic acid; Ag; antigen; BMMC; bone marrow mast cells; C1P; ceramide-1-phosphate; Cer; ceramide; DAG; diacylglycerol; DHS; d,l-threo-dihydrosphingosine; DMS; N,N-dimethylsphingosine; ERK; extracellular signal-regulated kinase; GPCR; G-protein co

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Convergent loss of an anciently duplicated, functionally divergent RH2 opsin gene in the fugu and Tetraodon pufferfish lineages

Keywords: LTR; long terminal repeat; GPCR; G-protein-coupled receptor; Pseudogenes; Gene duplication; Transposable elements; Takifugu rubripes; Pufferfish;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Mechanisms of allosteric modulation at GABAB receptors by CGP7930 and GS39783: effects on affinities and efficacies of orthosteric ligands with distinct intrinsic properties

Keywords: CGP7930; GS39783; GABAB receptor; Allosteric modulation; Affinity; Efficacy; CAMP; cyclic 3′,5′-adenosine-monophosphate; CHO; Chinese hamster ovary; 7β-forskolin; 7-deacetyl-7-(O-N-methylpiperazino)-γ-butyryl-forskolin, dihydrochloride; GABA; γ-ami

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Organization and expression study of the shrimp (Metapenaeus ensis) putative 5-HT receptor: Up-regulation in the brain by 5-HT

Keywords: 5-HT; serotonin (or 5-hydroxytryptamine); 5-HTI; 5-HT receptor; CHH; crustacean hyperglycemic hormone; CNS; central nervous system; GIH; gonad inhibiting hormone; GPCR; G-protein coupled receptor; MIH; molt inhibiting hormone; RT-PCR; reverse transcriptas

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

Sub-cellular distribution of endothelin signaling pathway components in ventricular myocytes and heart: lack of preformed caveolar signalosomes

Keywords: Lipid rafts; Caveolae; Endothelin; ERK; Signalosome; ACVM; adult rat cardiac ventricular myocyte; c.v.c.; colocalized voxels per cell; DAG; diacylglycerol; DIG; detergent-insoluble glycosphingolipid-enriched; ERK; extracellular signal-regulated protein ki

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

Post-translational control of chemokines: a role for decoy receptors?

Keywords: Chemokines; Leukocyte migration; Decoy receptor; Proteases; Viral homologues; Antagonists; ADAM; a disintegrin and metalloproteinase; CCL; CC chemokine ligand; CCR; CC chemokine receptor; CXCL; CXC chemokine ligand; CXCR; CXC chemokine receptor; CX3CL; CX

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

Multiple interaction sites of galnon trigger its biological effects

Keywords: AR; adrenoreceptor; AVP; [Arg8]vasopressin; CHO; Chinese hamster ovary; D1(2)R; dopamine receptors, type 1 (2); DMSO; dimethylsulfoxide; GalR; galanin receptor; GPCR; G-protein coupled receptors; HKR; Hepes-Krebs-Ringer solution; HPLC; high performanc

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

Ins(1,4,5)P3 receptors and inositol phosphates in the heart-evolutionary artefacts or active signal transducers?

Keywords: Inositol phosphates; Phospholipase C; Arrhythmia; Hypertrophy; α1-AR; α1-adrenergic receptor; ANP; atrial natriuretic factor; APD; action potential duration; CaMKII; Ca2+/calmodulin-dependent protein kinase II; CnA; calcineurin A; DAG; sn-1,2-diacylglyc

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

Two G protein-coupled receptors activate Na+/H+ exchanger isoform 1 in Chinese hamster lung fibroblasts through an ERK-dependent pathway

Keywords: BCECF; 2′,7′-bis-(carboxyethyl)-5-(and-6)-carboxyfluorescein; ERK; extracellular signal-regulated kinase; GPCR; G protein-coupled receptors; KI-MEK1; kinase inactive MAP kinase/ERK kinase 1; LPA; lysophosphatidic acid; NHE1; sodium hydrogen exchanger

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

Behavioral actions of neuropeptides in invertebrates: Insights from Drosophila

Keywords: Molt; Ecdysis; Neurohormone; Circadian; Eclosion; GPCR;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

Activation and nuclear translocation of ERK1/2 by the formyl peptide receptor is regulated by G protein and is not dependent on β-arrestin translocation or receptor endocytosis

Keywords: GPCR; G protein-coupled receptor; ERK1/2; extracellular signal regulated kinases 1 and 2; FPR; N-formyl peptide receptor; GRK; G protein-coupled receptor kinase; fMLF; N-formyl-methionyl-leucyl-phenylalanine; CHO; Chinese hamster ovary; MAPK; mitogen-acti

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

The mouse chemerin receptor gene, mcmklr1, utilizes alternative promoters for transcription and is regulated by all-trans retinoic acid

Keywords: CMKLR1; chemoattractant-like receptor 1; GPCR; G-protein-coupled receptor; EMSA; electrophoretic mobility shift assay; AP-1; activator protein 1; AP-4; activator protein 4; GATA-1/-2/-3; GATA-binding factor -1, -2 or -3; CREB; cAMP-responsive element bind

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2005 سفارش ترجمه

Dimerization of chemokine receptors and its functional consequences

Keywords: Chemokines; GPCR; Dimerization; Cooperativity;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2005 سفارش ترجمه

Establishment of robust functional assays for the characterization of neuropeptide Y (NPY) receptors: identification of 3-(5-benzoyl-thiazol-2-ylamino)-benzonitrile as selective NPY type 5 receptor antagonist

Keywords: Neuropeptide Y receptor; Ligand binding; Cyclic AMP inhibition; GTPγS binding; Fluorimetric imaging plate reader; Antagonism; NPY; Neuropeptide Y; PYY; Peptide YY; PP; Pancreatic Polypeptide; Y; NPY receptor; FLIPR; fluorimetric image plate reader; GPCR;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2005 سفارش ترجمه

Bile acid-induced proliferation of a human colon cancer cell line is mediated by transactivation of epidermal growth factor receptors

Keywords: MAPK; mitogen activated protein kinase; M3R; M3 subtype muscarinic receptor; ACh; acetylcholine; p90RSK; p90 ribosomal S kinase; EGFR; epidermal growth factor receptor; DCT; deoxycholyltaurine; DCG; deoxycholylglycine; LCT; lithocholyltaurine; GPCR; G-pro

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2005 سفارش ترجمه

Phosphorylation-independent internalisation and desensitisation of the human sphingosine-1-phosphate receptor S1P3

Keywords: S1P; d-erythro-sphingosine-1-phosphate; G-protein; guanine nucleotide-binding regulatory protein; ERK; extracellular signal-regulated kinase; GPCR; G-protein-coupled receptor; GRK; G-protein-coupled receptor kinase; PKC; protein kinase C; GFP; green fluor

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2005 سفارش ترجمه

Two different pathways link G-protein-coupled receptors with tyrosine kinases for the modulation of growth and survival in human hematopoietic progenitor cells

Keywords: AG 82; AG 490, tyrphostin tyrosine kinase inhibitors; BFU-E; burst forming unit-erythroid; CXCR4; CXC-chemokine receptor 4, specifically recognizing CXCL12; Epo; erythropoietin; Flt-3L; ligand of flt-3 receptor; G-CSF; granulocyte colony-stimulating facto

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2005 سفارش ترجمه

Evidence for novel cannabinoid receptors

Keywords: Endocannabinoids; Cannabinoid receptors; Endothelium; Vasodilation; Hippocampus; 2-AG; 2-arachidonoylglycerol; abn-cbd; abnormal cannabidiol; BKCa; large conductance calcium-activated potassium channel; CGRP; calcitonin gene-related peptide; DSI or DSE; d

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2005 سفارش ترجمه

The repertoire of trace amine G-protein-coupled receptors: large expansion in zebrafish

Keywords: Rhodopsin; GPCR; Evolution; Zebrafish; Fugu; Trace amine; Monoamine; Syntheny;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2005 سفارش ترجمه

Differential ion current activation by human 5-HT1A receptors in Xenopus oocytes: Evidence for agonist-directed trafficking of receptor signalling

Keywords: GPCR; 5-HT1A receptor; Agonist trafficking; Electrophysiology; Xenopus oocytes;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2005 سفارش ترجمه

Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors

Keywords: β-PEA; β-phenylethylamine; 5-HT; 5-hydroxytryptamine; EIA; enzyme immunoassay; GPCR; G protein-coupled receptor; LPV; ligand pocket vector; OCT; octopamine; PCR; polymerase chain reaction; p-TYR; p-tyramine; TA; trace amine; TAAR; trace amine-associated

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2005 سفارش ترجمه

Evolutionary conservation of the structural, pharmacological, and genomic characteristics of the melanocortin receptor subtypes

Keywords: Melanocortin receptor; MSH; ACTH; GPCR; Evolution;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2005 سفارش ترجمه

c-Src is involved in regulating signal transmission from PDGFβ receptor-GPCR(s) complexes in mammalian cells

Keywords: ASM; airway smooth muscle; CHO; Chinese hamster ovary; Con A; concanavalin A; Gi; inhibitory G protein; Giα; alpha sub-unit of Gi; Gab1; Grb-2 associated binder-1; GRK; G protein-coupled receptor kinase; GPCR; G protein-coupled receptor; Grb-2; growth fa

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2005 سفارش ترجمه

Δ12-Prostaglandin D2 is a potent and selective CRTH2 receptor agonist and causes activation of human eosinophils and Th2 lymphocytes

Keywords: CRTH2; chemoattractant receptor-homologous molecule expressed on Th2 cells; Dk-PGD2; 13,14-dihydro-15-keto-PGD2; DP; D prostanoid receptor; GPCR; G protein-coupled receptor; 15d-PGD2; 15-deoxy-Δ12,14PGD2; PGD2; prostaglandin D2; PTX; Bordella pertussis t

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2005 سفارش ترجمه

Lipids, lipid rafts and caveolae: Their importance for GPCR signaling and their centrality to the endocannabinoid system

Keywords: Lipid bilayer; Lipid raft; Caveolae; GPCR; Cannabinoid; Endocannabinoid;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2005 سفارش ترجمه

The therapeutic potential in targeting CCR5 and CXCR4 receptors in infectious and allergic pulmonary disease

Keywords: CCR5; CCL5; CXCR4; Asthma; Airway remodeling; [44AANA47]-RANTES; Arg44, Lys45 Arg47 mutated to Ala in RANTES/CCL5; ABPA; allergic bronchopulmonary aspergillosis; AdCCL5; recombinant human type-5 adenovirus containing a murine CCL5 cDNA; A. fumigatus; Aspe

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2005 سفارش ترجمه

The gene repertoire and the common evolutionary history of glutamate, pheromone (V2R), taste(1) and other related G protein-coupled receptors

Keywords: ADH; Adhesion family; BLAST; basic local alignment search tool; BLAT; blast like alignment tool; CASR; calcium-sensing receptor; CNS; central nervous system; EST; expressed sequence tag; GABA; gamma-aminobutyric acid; GPCRs; G protein-coupled receptors; G

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2005 سفارش ترجمه

Origin of the prolactin-releasing hormone (PRLH) receptors: Evidence of coevolution between PRLH and a redundant neuropeptide Y receptor during vertebrate evolution

Keywords: PRLH; prolactin-releasing hormone; PRLHR; PRLH receptor; NPYR; neuropeptide Y receptor; GPCR; G-protein-coupled receptor; ACTH; adrenocorticotropin; TM; transmembrane region; EL; extracellular loop; HMM; Hidden Markov Model; LG; linkage group; PRH; prolac

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2005 سفارش ترجمه

Synaptic and extrasynaptic GABA-A and GABA-B receptors in the globus pallidus: An electron microscopic immunogold analysis in monkeys

Keywords: post-embedding; striatopallidal; high pressure freezing; subthalamic nucleus; Parkinson's disease; extrasynaptic receptor; pallidum; ABC; avidin-biotin complex; BSA; bovine serum albumin; GABA-A; GABA receptor subtype A; GABA-B; GABA receptor subtype

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2005 سفارش ترجمه

HIV chemokine receptor inhibitors as novel anti-HIV drugs

Keywords: AIDS; acquired immune deficiency syndrome; AOP; aminooxypentane; CI; clinical isolate; DC; dendritic cell; DC-SIGN; dendritic cell-specific ICAM-3-grabbing nonintegrin; FDA; Food and Drug Administration; FLIPR; fluorometric imaging plate reader; GCP; gran

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2005 سفارش ترجمه

Synergy in cytokine and chemokine networks amplifies the inflammatory response

Keywords: AP; activating protein; BCA; B cell attracting chemokine; CBP; CREB-binding protein; CCL; CC chemokine ligand; CXCL; CXC chemokine ligand; CCR; CC chemokine receptor; CXCR; CXC chemokine receptor; CRE; cAMP-response element; GPCR; G protein-coupled recept

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2005 سفارش ترجمه

TRP channels: An overview

Keywords: 2-ABP; 2-aminoethoxydiphenyl borate; ADPKD; autosomal dominant polycystic kidney disease; BDNF; brain-derived neurotrophic factor; CaM; calmodulin; CIRB; CaM and IP3R binding site; DAG; diacylglycerol; DRG; dorsal root ganglion; 5′,6′-EET; 5′,6′-e

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2005 سفارش ترجمه

New insights into the retinal circulation: Inflammatory lipid mediators in ischemic retinopathy

Keywords: cAMP; adenosine 3′; 5′-cyclic monophosphate; AA; arachidonic acid; COX; cyclooxygenase; ChBF; choroidal blood flow; DHA; docosahexaenoic acid; GPCR; G protein-coupled receptor; IP3; inositol 1; 4; 5-triphosphate; NOS; nitric oxide synthase; iNOS; indu

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2005 سفارش ترجمه

The role of cholesterol in rod outer segment membranes

Keywords: Cholesterol; Rhodopsin; Rod outer segment; GPCR;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2005 سفارش ترجمه

Therapeutic potential of adenosine A2A receptor antagonists in Parkinson's disease

Keywords: Adenosine A2A receptor; Caffeine; Dyskinesia; Neuroprotection; Parkinson's disease; Striatum; 6-OHDA; 6-hydroxydopamine; ACh; acetylcholine; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; APEC; 2-[(2-aminoethylamino)carbonylethyl-phenylethyl

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2005 سفارش ترجمه