دانلود مقالات ISI درباره Gpcr + ترجمه فارسی

α2-Adrenergic receptor subtype-specific activation of NF-κB in PC12 cells

Keywords: α2-ARs; α2-adrenergic receptors; GPCR; G-protein coupled receptor; CNS; central nervous system; KO; knock-out; MAPK; mitogen-activated protein kinase; AP-1; activator protein-1; NF-κB; nuclear factor-kappaB; PI-3K; phosphatidyl inositol-3′OH kinase;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Identification of four evolutionarily related G protein-coupled receptors from the malaria mosquito Anopheles gambiae

Keywords: GPCR; DRY motif; Neuropeptide; Neurohormone; GnRH; Endocrinology; Malaria; Insect; Drosophila; Mosquito; Silkworm

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Prediction of GPCR-G Protein Coupling Specificity Using Features of Sequences and Biological Functions

Keywords: GPCR; G protein; coupling specificity; NLP; C4.5; text mining

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Cellular mechanisms that determine selective RGS protein regulation of G protein-coupled receptor signaling

Keywords: RGS; GPCR; G protein; Desensitization; 7TM receptor

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Novel reciprocal regulation of cAMP signaling and apoptosis by orphan G-protein-coupled receptor GPRC5A gene expression

Keywords: GPRC5A; GPCR; Orphan GPCR; cAMP; Gsα; Apoptosis; Cancer; Negative feedback

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Characterization of the desensitization properties of five dopamine receptor subtypes and alternatively spliced variants of dopamine D2 and D4 receptors

Keywords: Signaling; Desensitization; GPCR; GRK; β-Arrestin; Dopamine receptor; SH3-binding domain

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Regulation of pharmacology by hetero-oligomerization between A1 adenosine receptor and P2Y2 receptor

Keywords: GPCR; Hetero-oligomer; Dimer; Purinergic receptor; P2 receptor; Adenosine receptor; Calcium mobilization; Adenylate cyclase; HEK293T

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Probing rhodopsin–transducin interaction using Drosophila Rh1–bovine rhodopsin chimeras

Keywords: Rhodopsin; Drosophila rhodopsin Rh1; Transducin; GPCR; G proteins; Phototransduction

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

G protein-coupled receptor 12 deficiency results in dyslipidemia and obesity in mice

Keywords: RER; Neuronal expression; Energy balance; Energy expenditure; Dyslipidemia; GPCR

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Role of N-glycan-dependent quality control in the cell-surface expression of the AT1 receptor

Keywords: AT1 receptor; GPCR; N-glycosylation; Oligosaccharide trimming; Quality control

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Enantiomeric N-methyl-4-piperidyl benzilates as muscarinic receptor ligands: Radioligand binding studies and docking studies to models of the three muscarinic receptors M1, M2 and M3

Keywords: Chiral benzilic acid derivatives; Muscarinic antagonists; Muscarinic receptors (M1, M2, M3); Molecular modelling; 4-DAMP; 4-diphenylacetoxy-N-methylpiperidine methiodide; E; extracelluar loop; EL; energy of the isolated ligand; ER; energy of the empty rec

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

G protein-coupled receptor for diapause hormone, an inducer of Bombyx embryonic diapause

Keywords: G protein-coupled receptor; GPCR; Diapause hormone; FXPRL-amide; Neuropeptide; Peptide hormone; Bombyx mori; Embryonic diapause; Maternal control factor; Pheromone biosynthesis-activating neuropeptide

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Sensitive determination of G-protein-coupled receptor binding ligands by solid phase extraction–electrospray ionization–mass spectrometry

Keywords: GPCR; Histamine H2-receptor; SPE–MS; Mass spectrometry

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Functional domains of the subtype 1 neurotensin receptor (NTS1)

Keywords: NTS1; GPCR; G proteins; Agonist; Antagonist; Constitutive activity

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Comparative analysis of the human angiotensin II type 1a receptor heterologously produced in insect cells and mammalian cells

Keywords: GPCR; Angiotensin receptor; Overexpression; BHK cells; Insect cells; Glycosylation; Localization

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

NeuropharmacologyCharacterization of CB1 cannabinoid receptor immunoreactivity in postmortem human brain homogenates

Keywords: prefrontal cortex; dimerization; glycosylation; GPCR; Western-blot; postmortem-delay; DTT; dithiothreitol; ECL; enhanced chemiluminescence; EGTA; ethylene glycol-bis (β-aminoethyl ether); OD; optical density; PMD; postmortem delay; PMSF; phenylmethylsulf

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Signaling mechanisms in progesterone-neurotransmitter interactions

Keywords: progesterone receptors; ligand-independent activation; signaling; reproductive behavior; protein kinases; dopamine; AF; transcription activation function; CBP; CREB-binding protein; CREB; cyclic AMP responsive element binding protein; DA; dopamine; DARPP-

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Manipulation of small-molecule inhibitory kinetics modulates MCH-R1 function

Keywords: MCH receptor; GPCR; Antagonist; Kinetics

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Development and validation of a platelet calcium flux assay using a fluorescent imaging plate reader

Keywords: Platelets; Calcium; GPCR; FLIPR; Thromboxane receptor; Purinergic receptors; Ion channel

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Characterization of the binding of [3H]CGP54626 to GABAB receptors in the male bullfrog (Rana catesbeiana)

Keywords: GABA; Modulation; CGP54626; Taurine; Amphibian; GPCR

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

RGS17/RGSZ2 and the RZ/A family of regulators of G-protein signaling

Keywords: G-protein; Palmitoylation; Ubiquinylation; Cysteine string; GIPC; GAP; MAPK; cAMP; Calcium; Receptor; Dopamine; GPCR; Clathrin; Golgi; Vesicles

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

d-myo-Inositol 1-phosphate as a surrogate of d-myo-inositol 1,4,5-tris phosphate to monitor G protein-coupled receptor activation

Keywords: GPCR; HTRF; Inositol phosphate; IP3; IP1; Signal transduction; Membrane receptor

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Functional characterization of the modified melanocortin peptides responsible for ligand selectivity at the human melanocortin receptors

Keywords: Obesity; SHU9119; MC3R; MC4R; GPCR

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Interactions between GABA-B1 receptors and Kir 3 inwardly rectifying potassium channels

Keywords: GABA; Kir 3 potassium channels; GPCR; Signalling; Protein trafficking

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Identification and characterization of five-transmembrane isoforms of human vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide receptors

Keywords: Vasoactive intestinal peptide receptors; Splice variants; Five-transmembrane; VIPR1; VPAC1; VIPR2; VPAC2; GPCR;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

The application of a 3D-QSAR (autoMEP/PLS) approach as an efficient pharmacodynamic-driven filtering method for small-sized virtual library: Application to a lead optimization of a human A3 adenosine receptor antagonist

Keywords: GPCR; A3 adenosine receptor antagonist; 3D-QSAR; Molecular modeling;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Bacterial expression of functional, biotinylated peripheral cannabinoid receptor CB2

Keywords: Peripheral cannabinoid receptor CB2; Biotinylation; GPCR; Affinity purification; Expression tag removal

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

Activation of Src/kinase/phospholipase c/mitogen-activated protein kinase and induction of neurite expression by ATP, independent of nerve growth factor

Keywords: ATP; P2Y receptor; MAP kinase; neurite outgrowth; neuro2a cells; BSA; bovine serum albumin; ERK; extracellular signal-regulated kinase; GPCR; G-protein-coupled receptor; MEK; MAP kinase/ERK kinase kinase; MAPK; mitogen-activated protein kinase; NECA; 5′

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

The challenge of drug discovery of a GPCR target: Analysis of preclinical pharmacology of histamine H3 antagonists/inverse agonists

Keywords: H3 receptor; Histamine; GPCR; Drug discovery; Cognition; Antagonist/inverse agonist

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

Comprehensive repertoire and phylogenetic analysis of the G protein-coupled receptors in human and mouse

Keywords: GPCR; Glutamate; Rhodopsin; Adhesion; Frizzled; Taste2; SecretinBLAST, basic local alignment search tool; BLAT, BLAST-like alignment tool; EST, expressed sequence tag; GPCR, G protein-coupled receptor; HMM, Hidden Markov model; MP, maximum parsimony; RPS-

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

Alanine scanning mutagenesis of the chemokine receptor CCR3 reveals distinct extracellular residues involved in recognition of the eotaxin family of chemokines

Keywords: mAb, Monoclonal antibody; RPE, Rhodamine phycoerythrin; ANOVA, analysis of variance; SEM, Standard error of the mean; WT, Wild-type; ECL, Extracellular loopChemokine; Chemokine receptors; GPCR; Inflammation; Allergy

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

In vitro reconstitution and preparative purification of complexes between the chemokine receptor CXCR4 and its ligands SDF-1α, gp120–CD4 and AMD3100

Keywords: GPCR; CXCR4; gp120; HIV; SDF-1α; Baculovirus

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

Contribution of the kinetics of G protein dissociation to the characteristic modifications of N-type calcium channel activity

Keywords: GPCR; G protein coupled receptors; DAMGO; d-Ala2,Me-Phe4,glycinol5)-enkephalin; Calcium channel; N-type channel; G protein regulation; μ-Opioid receptor; β-Subunit; Prepulse facilitation; Channel reluctance;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

Xapelin and Xmsr are required for cardiovascular development in Xenopus laevis

Keywords: Apelin; Xmsr; GPCR; APJ; Heart; Endothelium; Blood; XlFli

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2006 سفارش ترجمه

G-protein and cAMP-mediated signaling in aspergilli: A genomic perspective

Keywords: Neurospora crassa; Magnaporthe grisea; Fusarium graminearum; Regulator of G-protein signaling; Aspergillus; cAMP; G-protein; GPCR; PKA; Nutrient sensing

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2006 سفارش ترجمه

Mass-dependent signaling between G protein coupled receptors

Keywords: GPCR; G-protein coupled receptors (GPCR); TPR; Thromboxane A2 Receptor; PAFR; Platelet activating factor receptor; PRP; platelet rich plasma; CHO-TPR/PAFR; TPR/PAFR co-expressing CHO cell line; CHO-TPRind/PAFRind; Inducible TPR/PAFR co-expressing CHO cell

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2006 سفارش ترجمه

Interaction of small molecule inhibitors of HIV-1 entry with CCR5

Keywords: GPCR; CCR5; CCR5 inhibitors; HIV-1; TAK-779; AD101; SCH-C

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2006 سفارش ترجمه

Defective postnatal development of the male reproductive tract in LGR4 knockout mice

Keywords: GPCR; LGR; GPR48; Male infertility; Epididymis; Efferent ducts; Tubulogenesis; Duct elongation; Proliferation; Epithelial–mesenchymal interactions

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2006 سفارش ترجمه

Mammalian RGS proteins: Multifunctional regulators of cellular signalling

Keywords: RGS protein; GPCR; Signalling; Regulation

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2006 سفارش ترجمه

Role of heterotrimeric G-proteins in lysophosphatidic acid-mediated neurite retraction by RhoA-dependent and -independent mechanisms in N1E-115 cells

Keywords: DMSO; dimethyl sulphoxide; EYFP; enhanced yellow fluorescent protein; FBS; fetal bovine serum; GPCR; G-protein coupled receptor; GST; glutathione-s-transferase; HA3; triple hemagglutinin epitope tag; IBMX; 3-isobutyl-1-methylxanthine; InsP3; inositol-1,4,

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2006 سفارش ترجمه

Homologous desensitization of signalling by the beta (β) isoform of the human thromboxane A2 receptor

Keywords: C-tail; carboxyl-terminal tail; [Ca2+]i; intracellular calcium; FBS; foetal bovine serum; GPCR; G protein-coupled receptor; GRK; G protein-coupled receptor kinase; HA; hemagglutinin; HEK; human embryonic kidney; IP; prostacyclin receptor; IP3; inositol 1,

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2006 سفارش ترجمه

Identification and characterization of surrogate peptide ligand for orphan G protein-coupled receptor mas using phage-displayed peptide library

Keywords: Angiotensin; GPCR; Mas; Oncogene; Peptide library; Phage display

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2006 سفارش ترجمه

Novel ligands for the human histamine H1 receptor: Synthesis, pharmacology, and comparative molecular field analysis studies of 2-dimethylamino-5-(6)-phenyl-1,2,3,4-tetrahydronaphthalenes

Keywords: GPCR; Histamine receptor; Inositol phosphates; Intracellular signaling; Molecular modeling; Neurotransmitter; PLC; QSAR; Serotonin receptor; Tetrahydronaphthalene

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2006 سفارش ترجمه

GPCR modulation by RAMPs

Keywords: Calcitonin receptor; CL receptor; Family B GPCR; GPCR; RAMP; VPAC1 receptorAM, adrenomedullin; AMY, amylin; CGRP, calcitonin gene-related peptide; CL, calcitonin receptor-like receptor; CT, calcitonin; GPCR, G-protein coupled receptor; NHERF, Na+/H+ excha

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2006 سفارش ترجمه

Molecular mechanisms underlying the modulation of exocytotic noradrenaline release via presynaptic receptors

Keywords: BoNT/A; botulinum neurotoxin type A; CAPS; Ca2+-dependent activator protein for secretion; DAG; diacylglycerol; Gβγ; G protein βγ subunits; GAP-43; growth associated protein of 43 kDa; GEFII; guanine nucleotide exchange factor II; GPCR; G protein-cou

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2006 سفارش ترجمه

Phospholipase C is involved in the adenosine-activated signal transduction pathway conferring protection against iodoacetic acid-induced injury in primary rat neuronal cultures

Keywords: Ado-STP; adenosine-induced signal transduction pathway; GPCR; G protein coupled receptors; IAA-R; iodoacetate-“reperfusion”; KATP channels; ATP sensitive potassium channels; PKC; protein kinase C; PLC; phospholipase C; R-PIA; N6-(R)-phenylisopropylade

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2005 سفارش ترجمه

Niacin mediates lipolysis in adipose tissue through its G-protein coupled receptor HM74A

Keywords: Niacin; Nicotinic acid; Lipolysis; Adipocyte; cAMP; GPCR;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2005 سفارش ترجمه

A bifunctional Gαi/Gαs modulatory peptide that attenuates adenylyl cyclase activity

Keywords: Adenylyl cyclase; Biosensors; G-proteins; Phage display; Signal transduction; Surface plasmon resonance; AC; adenylyl cyclase [E.C. 4.6.1.1]; AMP; adenosine monophosphate; cAMP; cyclic AMP; FITC; fluorescein isothiocyanate; FSK; forskolin; GDI; guanine nu

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2005 سفارش ترجمه

Chemical modification of the naphthoyl 3-position of JWH-015: In search of a fluorescent probe to the cannabinoid CB2 receptor

Keywords: Cannabinoid receptor; GPCR; Homology model; Fluorescent ligand

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2005 سفارش ترجمه

Prediction and Classification of Human G-protein Coupled Receptors Based on Support Vector Machines

Keywords: GPCR; prediction; classification; SVM;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2005 سفارش ترجمه