دانلود مقالات ISI درباره Gsk + ترجمه فارسی

بیماری آلزایمر و تغییرات میکروبی روده: راه طولانی بین مطالعات پیش از موعد و شواهد بالینی

Alzheimer's disease and gut microbiota modifications: The long way between preclinical studies and clinical evidence

Keywords: Aβ; amyloid-β-peptide; ACh; acetylcholine; Apo; apolipoprotein; APP; amyloid precursor protein; CYP; cytochrome P-450; DYRK1; dual specificity tyrosine-phosphorylation-regulated kinase 1A; GABA; γ-aminobutyric acid; GSK; glycogen synthase- kinase; HSV-

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

بررسی توصیه های واکسیناسیون روتاویروس در اروپا: دلایل تغییر

A review of recommendations for rotavirus vaccination in Europe: Arguments for change

Keywords: Rotavirus; Vaccine; National immunization program; AGE; acute gastroenteritis; GSK; GlaxoSmithKline; HRV; human rotavirus vaccine; HBRV; human-bovine reassortant rotavirus vaccine; RRV-TV; tetravalent rhesus-human rotavirus vaccine; RVGE; rotavirus gastro

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

گزارش کنفرانس بین المللی توالی نسل بعدی برای تشخیص ویروس های احتمالی در زیست شناسی

Report of the international conference on next generation sequencing for adventitious virus detection in biologicals

Keywords: Adventitious viruses; Biologics; Vaccines; Biotherapeutics; Cell substrate; Next generation sequencing; High throughput sequencing; Bioinformatics; NGS; next-generation sequencing; HTS; high-throughput sequencing; FDA; U.S. Food and Drug Administration; C

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2018 سفارش ترجمه

اثرات ضد سرطان از ترکیبات به طور طبیعی مشتق شده با هدف هیستون دیازتیلاز 6 مرتبط است

Anti-cancer effects of naturally derived compounds targeting histone deacetylase 6-related pathways

Keywords: FK228 (PubChem CID: 5352062); PXD101 (PubChem CID: 6918638); SAHA (PubChem CID: 5311); LBH-589 (PubChem CID: 6918837); tubacin (PubChem CID: 6675804); tubastatin A (PubChem CID: 49850262); ACY-1215 (PubChem CID: 53340666); ACY-241 (PubChem CID: 53340426);

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2018 سفارش ترجمه

مدولاسیون بازسازی همزمان با سولفورفان باعث کاهش دیابت و سندرم قلبی می شود

Concerted redox modulation by sulforaphane alleviates diabetes and cardiometabolic syndrome

Keywords: ACS; Acyl-CoA synthetase; ARE/EpRE; Antioxidant/electrophile response element; Bcl-2; B-cell lymphoma 2; BMI; Body mass index; BSP; Broccoli sprout powder; CAT; Catalase; C/EBP; CCAAT/enhancer-binding protein; CD36; CD36 molecule/thrombospondin receptor;

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

مدلهای سلولی و بافتی فیبروز ریوی مهندسی شده

Engineered cell and tissue models of pulmonary fibrosis

Keywords: CHAPS; 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate; ALI; air-liquid interface; α-SMA; alpha-smooth muscle actin; ATII; alveolar type II cells; ATS; American Thoracic Society; AFM; atomic force microscopy; COPD; Chronic Obstructive Pulmonary

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2018 سفارش ترجمه

دیدگاه های جدید برای گلیکوئید های طبیعی تریترپن به عنوان متخصصین بالقوه

New perspectives for natural triterpene glycosides as potential adjuvants

Keywords: Triterpene glycosides; Adjuvant; Cancer; Targeted toxins; Antimicrobial; Anti-inflammatory; Vaccines; QS-21; AD; Alzheimer's disease; AIDS; acquired immune deficiency syndrome; AS; adjuvant system; Aβ; amyloid β; APC; antigen presenting cells; Api; apio

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2017 سفارش ترجمه

Recent advancements in the development of anti-tuberculosis drugs

Keywords: ADRs; adverse drug reactions; AG; arabinogalactan; AhpE; alkylhydroperoxide reductase E; Alr; d-alanine racemase; AMP; adenosine monophosphate; AnPRT; anthranilate phosphoribosyltransferase; ATP; adenosine triphosphate; BTZ; benzothiazinone; CADD; compute

دانلود رایگان متن کامل مقاله ISI 61 صفحه سال انتشار : 2017 سفارش ترجمه

مولکول های زیست فعال مشتق از سلول های بنیادی مزانشیمی بند ناف

Bioactive molecules derived from umbilical cord mesenchymal stem cells

Keywords: ACTH; adrenocorticotropic hormone; aFGF; acidic fibroblast growth factor; Akt; activation of protein kinase B; ANG; angiogenin; ASCs; adipose tissue-derived mesenchymal stem cells; B7-H1; B7 homolog 1; BDNF; brain-derived neurotrophic factor; bFGF; basic

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

پلی ساکارید ضد دیابت از منابع طبیعی: یک بررسی

Anti-diabetic polysaccharides from natural sources: A review

Keywords: AGE-RAGE; advanced glycation end products; AI; atherogenic index; AMPK; AMP-activated protein kinase; Ara; arabinose; Bax; pro-apoptotic Bcl2-associated X; Bcl-2; B-cell leukaemia/lymphoma 2; BG; blood glucose; CAT; catalase; Fuc; fucose; FBG; fasting blo

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2016 سفارش ترجمه

انتقال نفوذپذیری میتوکندری: ذرات مولکولی و نقش آن به عنوان یک هدف در حفاظت از قلب

The mitochondrial permeability transition pore: Molecular nature and role as a target in cardioprotection

Keywords: ANT; adenine nucleotide translocase; CsA; cyclosporin A; CyP; cyclophilin; Drp1; dynamin-related protein 1; Δψm; mitochondrial membrane potential; ERK; extracellular signal regulated kinase; GSK; glycogen synthase kinase; IMM; inner mitochondrial membra

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

مرگ ناگهانی نورونال اولیه باعث ایجاد نوروژنز ناشی از ایسکمی مغزی در گوروس دندانه

Early immature neuronal death initiates cerebral ischemia-induced neurogenesis in the dentate gyrus

Keywords: aCSF; artificial cerebrospinal fluid; BDNF; brain-derived neurotropic factor; BrdU; bromodeoxyuridine; DG; dentate gyrus; DMSO; dimethyl sulfoxide; EDTA; ethylenediaminetetraacetic acid; EGTA; ethylene glycol tetraacetic acid; GSK; glycogen synthase kinas

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

مدل های ترکیبی اثر گذار اپیتلیال-مزانشیمال نشان می دهد که شبکه های سیگنالینگ مجددا راه اندازی می شوند

Mixed-effects model of epithelial-mesenchymal transition reveals rewiring of signaling networks

Keywords: AKT; protein kinase B; ATM; ataxia-telangiectasia mutated; ELISA; enzyme-linked immunosorbent assay; EMT; epithelial-mesenchymal transition; ERK; extracellular signal-regulated kinase; GSK; glycogen synthase kinase; hSAEC; human small airway epithelial

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

سیلیمارین و ترکیبات آن در پیشگیری از قلب

Silymarin and its constituents in cardiac preconditioning

Keywords: AC; adenylyl cyclase; ALDH; aldehyde dehydrogenase; ANT; adenine nucleotide transporter; AR; adrenergic receptor; ARE; antioxidant response element; ATP; adenosine triphosphate; cAMP; cyclic adenosine monophosphate; COX; cyclo-oxygenase; CsA; cyclosporine

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

مقاله اصلی در دسترس بودن داده های غربالگری کانال یون بالا و پیامدهای آن برای ارزیابی ایمنی قلب

Original articleVariability in high-throughput ion-channel screening data and consequences for cardiac safety assessment

Keywords: AP(D); Action Potential (Duration); AZ; AstraZeneca; FLIPR; FLuorometric Imaging Plate Reader; GSK; GlaxoSmithKline; HTS; High Throughput Screening [assays]; IC50; Concentration for 50% Inhibition; ICaL; L-type calcium current; IKr; rapid delayed rectifie

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

MicroRNA-204-5p regulates 3T3-L1 preadipocyte proliferation, apoptosis and differentiation

Keywords: C/EBPα; CCAAT/enhancer-binding proteins; PPAR-γ; peroxisome proliferator activated receptor-γ coactivator; AP2; adipocyte fatty-acid binding protein 2; CDK4; cyclin dependent kinase 4; CDK2; cyclin dependent kinase 2; CDK5; cyclin dependent kinase 5; p

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

6,7,4′-Trihydroxyisoflavone suppressed the estrogen receptor negative breast cancer growth via regulating glycogen synthase kinase-3β/β-catenin signaling

Keywords: Breast cancer; β-catenin; Cell cycle; Glycogen synthase kinase-3β; Trihydroxyisoflaovone; CDK; cyclin dependent kinase; CDKI; cyclin dependent kinase inhibitor; ER; estrogen receptor; ERK; extracellular signal-regulated kinase; GSK; glycogen synthase ki

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Apelin, a promising target for Alzheimer disease prevention and treatment

Keywords: Alzheimer disease; Apelin; Amyloid beta; Central nervous system; Oxidative stress; AAA; Abdominal aortic aneurysm; ABCA1; ATP-binding cassette transporter A1; ACE; Angiotensin converting enzyme; ACh; Acetylcholine; AChE; Acetyl choline esterase; AD; Alzhe

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Kindlins: Roles in development and cancer progression

Keywords: AML; acute myeloid leukemia; AR; androgen receptor; CRC; colorectal cancer; DC; dendritic cells; EC; esophageal cancer; ECM; extracellular matrix; EMT; endothelial/mesenchymal transition; ESCC; esophageal squamous cell cancer; FERM; 4.1-ezrin-ridixin-moes

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

Signal management in pharmacovigilance and human risk assessment of CpG 7909, integrating embryo-fetal and post-natal developmental toxicity studies in rats and rabbits

Keywords: BW; body weight; CpG; unmethylated 2′ deoxyribo (cytidine-phosphate-guanosine); EFD; embryo-fetal development; EMA; European Medicines Agency; FDA; Food and Drug Administration; G0; day 0 of gestation; GSK; GlaxoSmithKline; HLS; Huntington Life Sciences

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Syndecan-1 inhibits early stages of liver fibrogenesis by interfering with TGFβ1 action and upregulating MMP14

Keywords: SDC1; syndecan-1; TGFβ1; transforming growth factor-β1; MAPK; matrix activated protein kinase; ECM; extracellular matrix; ERK; extracellular matrix regulated kinase; GSK; glycogen synthase kinase; αSMA; α smooth muscle actin; THBS1; thrombospondin-1;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

Antibody-drug conjugates (ADCs): Potent biopharmaceuticals to target solid and hematological cancers- an overview

Keywords: Antibody-drug conjugates; Monoclonal antibodies; Anticancer; Drug resistance; Solid tumors; Hematological tumors; ADC; Antibody-Drug Conjugate; ALCL; Anaplastic Large Cell Lymphoma; ALL; Acute Lymphoblastic Leukemia; AML; Acute Myeloid Leukemia; BCMA; B C

دانلود رایگان متن کامل مقاله ISI 62 صفحه سال انتشار : 2018 سفارش ترجمه

Exploring the multifaceted roles of heat shock protein B8 (HSPB8) in diseases

Keywords: Aβ; amyloid β-peptide; ACD; α-crystallin domain; AD; Alzheimer disease; ALS; amyotrophic lateral sclerosis; AR; androgen receptor; BAG3; BCL2 associated athanogene 3; BMP; bone morphogenetic protein; CASA; chaperone-assisted selective autophagy; CHIP;

دانلود رایگان متن کامل مقاله ISI 71 صفحه سال انتشار : 2018 سفارش ترجمه

Activation of Nrf2 signaling by natural products-can it alleviate diabetes?

Keywords: Nrf2; type 2 diabetes; natural products; hyperglycemia; cellular stress; insulin sensitivity; β-cell function; vascular complications; AGE; advanced glycation end products; AhR; arylhydrocarbon receptor; AMPK; AMP-activated kinase; ARE; antioxidant respo

دانلود رایگان متن کامل مقاله ISI 89 صفحه سال انتشار : 2018 سفارش ترجمه

CRMP1 and CRMP4 are required for proper orientation of dendrites of cerebral pyramidal neurons in the developing mouse brain

Keywords: ANOVA; analysis of variance; CA1; cornu ammonis 1; Cdk; cyclin dependent kinase; CNS; central nervous system; CRMP; collapsin response mediator protein; CRMP2ki/ki; CRMP2 knock-in; EDTA; ethylenediaminetetraacetic acid; GFP; green fluorescent protein; GSK

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

miR-199a-3p affects adipocytes differentiation and fatty acid composition through targeting SCD

Keywords: miR-199a-3p; Differentiation; Proliferation; Fatty acid composition; PPAR-γ; peroxisome proliferator activated receptor-g coactivator; C/EBP-α; CCAAT/enhancer-binding proteins; FAS; fatty acid synthase; ACC; acetyl-CoA carboxylase; GSK; glycogen synthas

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Extrinsic control of Wnt signaling in the intestine

Keywords: APC; Adenomatous polyposis coli; CAC; Colitis-associated cancer; CBC; Crypt base columnar; DKK; Dickkopf-related protein; FZD; Frizzled; GSK; Glycogen synthase kinase; IBD; Inflammatory bowel diseases; IFN; Interferon; IL; Interleukin; LGR; Leucine-rich r

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

WNT/β-catenin pathway modulates the TNF-α-induced inflammatory response in bronchial epithelial cells

Keywords: TNF-α; WNT; β-catenin; Inflammation; Bronchial epithelial cell; COPD; chronic obstructive pulmonary disease; Dvl; disheveled; Fz; frizzled; GSK; glycogen synthase kinase; IL; interleukin; LRP; lipoprotein receptor-related protein; MCP; monocyte chemoatt

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Defining the Na+/H+ exchanger NHE1 interactome in triple-negative breast cancer cells

Keywords: ACC1; acetyl-CoA carboxylase; AKT; protein kinase B, PKB; CAII; carbonic anhydrase II; CHP1; calcineurin B homologous protein 1; ER; estrogen receptor; ERK1/2; extracellular signal-regulated kinase 1/2; ERM; ezrin-radixin-moesin; FOXO3a; forkhead box O3a;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Production, purification and immunogenicity of recombinant Ebola virus proteins − A comparison of Freund's adjuvant and adjuvant system 03

Keywords: EBOV; Ebola virus; FCA; Freund's complete adjuvant; AS03; adjuvant system 03; GSK; GlaxoSmithKline; IFA; immunofluorescence assay; SDS-PAGE; sodium dodecyl sulphate polyacrylamide gel electrophoresis; IPTG; isopropyl-beta-thiogalactopyranoside; AEC; 3-ami

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Synthetic polyphenol compounds inhibit β-catenin/Tcf signaling: Structure-activity relationship

Keywords: APC; Axin-adenomatous polyposis coli; BCA; bicinchoninic acid; CBP; CREB binding protein; CRC; colorectal cancer; DMSO; dimethyl sulfoxide; Dsh; disheveled; EMSA; electrophoretic mobility shift assay; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; GSK;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

Modulation of signaling mechanisms in the heart by thioredoxin 1

Keywords: Akt; protein kinase B; AMPK; Adenosine Monophosphate-activated Protein Kinase; Ang-II; Angiotensin-II; AP1; Activator protein 1 (AP-1); ASK1; Apoptosis Signal-regulating kinase; Atg4; Autophagy related-4; ATP; Adenosine Triphosphate; CDDP; cis-diammine-di

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2017 سفارش ترجمه

Linking deregulation of non-coding RNA to the core pathophysiology of Alzheimer's disease: An integrative review

Keywords: Aβ42; β-amyloid42; ABCA1; ATP-Binding Cassette Transporter A1; AD; Alzheimers disease; ADAM; AD-related disintegrin and metalloprotease; AICD; APP- intracellular domain; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; ApoE; ApolipoproteinE;

دانلود رایگان متن کامل مقاله ISI 175 صفحه سال انتشار : 2017 سفارش ترجمه

In utero exposure to carcinogens: Epigenetics, developmental disruption and consequences in later life

Keywords: 5-mc; 5-methylcytosine; AhR; aryl hydrocarbon receptor; AKT; protein kinase B; BPA; bisphenol A; CNS; central nervous system; CS; cigarette smoke; DBP; dibenzo(α1) pyrene; DES; diethylstilboestrol; DNMT; N-methyltransferase; E2; 17-β-oestradiol; ED; end

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Alkynyl gold(I) phosphane complexes: Evaluation of structure-activity-relationships for the phosphane ligands, effects on key signaling proteins and preliminary in-vivo studies with a nanoformulated complex

Keywords: DFT; density functional theory; ERK; extracellular signal related kinase; FAK; focal adhesion kinase; GSK; glycogen synthase kinase; HSP; heat shock protein; MAPK; mitogen activated protein kinase; TOR; target of rapamycin; TrxR; thioredoxin reductase; Al

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

PEDF attenuates insulin-dependent molecular pathways of glucose homeostasis in skeletal myocytes

Keywords: PEDF; Skeletal muscle; Insulin resistance; Glucose; Akt; AS-160; akt substrate-160; Cbl; casitas B-lineage lymphoma; GSK; glycogen synthase kinase; IR; insulin receptor; IRS; insulin receptor substrate; PEDF; pigment epithelium-derived factor; PKB; protei

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

The ubiquitin-like modifier FAT10 in cancer development

Keywords: AIPL1; aryl-hydrocarbon receptor like-1; APC/C; anaphase-promoting complex/cyclosome; DUB; deubiquitylating enzyme; EMT; epithelial-mesenchymal transition; FAT10; HLA-F adjacent transcript 10; GSK; glycogen synthase kinase; HCC; hepatocellular carcinoma;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

WNT/β-catenin signaling promotes VSMCs to osteogenic transdifferentiation and calcification through directly modulating Runx2 gene expression

Keywords: VSMCs; vascular smooth muscle cells; AMC; arterial medial calcification; β-GP; β-glycerophosphoricacid; LRP; low density lipoprotein receptor-related protein; GSK; glycogen synthase kinase; PORCN; Porcupine; WNT/β-catenin signaling; Runx2; Vascular smo

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Functional role of inorganic trace elements in angiogenesis part III: (Ti, Li, Ce, As, Hg, Va, Nb and Pb)

Keywords: As; arsenic; FGF-2; basic fibroblast growth factor; BMP-2; bone morphogenetic protein-2; Ce; cerium; COX; cyclooxygenase; EC; endothelial cells; EPCR; endothelial cell protein C receptor; EPCs; endothelial progenitor cells; EMT; epithelial to mesenchymal

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2016 سفارش ترجمه

24-Methylenecycloartanyl ferulate, a major compound of γ-oryzanol, promotes parvin-beta expression through an interaction with peroxisome proliferator-activated receptor-gamma 2 in human breast cancer cells

Keywords: 24-Methylenecycloartanyl ferulate; Integrin-linked kinase; Parvin-β; PPAR-γ2; Akt1; 24-MCF; 24-methylenecycloartanyl ferulate; CAF; cycloartenyl ferulate; CH; calponin homology; ChIP; chromatin immunoprecipitation; CSF; campesteryl ferulate; DMEM; Dulbe

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Krüppel-like factor 5 incorporates into the β-catenin/TCF complex in response to LPA in colon cancer cells

Keywords: LPA; lysophosphatidic acid; KLF5; Krüppel-like factor 5; TCF; T-cell factor; LEF; lymphoid enhancer-binding factor; APC; adenomatous polyposis loci; GSK; glycogen synthase kinase; PI3K; phosphatidylinositol 3-kinase; IP; immunoprecipitation; ChIP; chroma

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

The role of exosomes and “exosomal shuttle microRNA” in tumorigenesis and drug resistance

Keywords: TD-exosomes; tumor-derived-exosomes; MVBs; multivesicular bodies; CEA; carcinoembryonic antigen; PTEN; phosphatase and tensin homologue; GSK; glycogen synthase kinase; NK; natural killer; MDR; multi-drug resistance; ABC; ATP-binding cassette; MAC; membran

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Scratching the surface: Exploratory analysis of key opinion leaders on rate limiting factors in novel adjuvanted-vaccine development

Keywords: CARG; compound annual growth rate; EPhMRA; European Pharmaceutical Marketing Research Association for the Anatomical Classification of Pharmaceutical Products; FDA; Food and Drug Administration; GSK; Glaxo Smith Kline; HBV; Hepatitis B Virus; HPV; Human P

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Comparison of Pandemrix and Arepanrix, two pH1N1 AS03-adjuvanted vaccines differentially associated with narcolepsy development

Keywords: 2D-DIGE; two dimensions difference gel electrophoresis; GSK; GlaxoSmithKline; HA; hemagglutinin; MA1; matrix protein 1; MS; mass spectrometry; NA; neuraminidase; NP; nucleoprotein; PB1; polymerase 1; Pandemrix; Arepanrix; Narcolepsy; Influenza A; H1N1; Va

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Pigment Epithelium-Derived Factor (PEDF) Inhibits Wnt/β-catenin Signaling in the Liver

Keywords: Extracellular Matrix; PEDF; Wnt/β-Catenin; BABB; benzyl alcohol/benzyl benzoate; CM; conditioned medium; ECM; extracellular matrix; ERK; extracellular signal-regulated kinase; FDR; false-discovery rate; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GO

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2015 سفارش ترجمه

Current knowledge and pharmacological profile of berberine: An update

Keywords: 5-HT; 5-hydroxytryptamine; 6-OHDA; 6-hydroxydopamine; AChE; acetylcholinesterase; AD; Alzheimer's disease; AMPK; AMP-activated protein kinase; BBB; blood brain barrier; BChE; butyrylcholinestesrase; CD; cluster of differentiation; Cdk; cyclin-dependent ki

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2015 سفارش ترجمه

Investigation of lactate calcium salt-induced β-catenin destabilization in colorectal cancer cells

Keywords: CaLa; lactate calcium salt; CRC; colorectal cancer; GSK; glycogen synthase kinase; APC; adenomatous polyposis coli; CBP; CREB binding protein; TCF; T-cell factor; PBS; phosphate-buffered saline; MG132; carbobenzoxy-Leu-Leu-leucinal; pGSK; phosphorylated G

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2015 سفارش ترجمه

Central acylated ghrelin improves memory function and hippocampal AMPK activation and partly reverses the impairment of energy and glucose metabolism in rats infused with β-amyloid

Keywords: GOAT; ghrelin O-acyltransferase; GHSR; growth hormone secretagogue receptor; LV; lateral ventricle; ICV; intracerebroventricular; AD-G; Acyl-ghrelin ICV infusion; AD-DES-G; Des-acyl-ghrelin ICV infusion; AD-C; phosphate buffered saline ICV infusion; Non-A

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2015 سفارش ترجمه

Structure-activity relationship and properties optimization of a series of Quinazoline-2,4-diones as inhibitors of the canonical Wnt pathway

Keywords: Wnt pathway; β-catenin; Small molecule; Structure-activity relationship; Glioblastoma; Fz; Frizzled; LRP; lipoprotein receptor-related protein; ACN; acetonitrile; APC; adenomatous polyposis coli; B/P; brain to plasma ratio; CDI; N,N′-carbonyl-diimida

دانلود رایگان متن کامل مقاله ISI 136 صفحه سال انتشار : 2015 سفارش ترجمه

IKK-β/NF-κB p65 mediates p27Kip1 protein degradation in arsenite response

Keywords: IKKβ; IκB kinase β; NF-κB; nuclear factor κB; Skp2; S-phase kinase associated protein 2; Kpc; Kip1 ubiquitination-promoting complex; CHX; cyclohexamide; GSK3; glycogen synthase kinase 3; Cul4a; Culin 4A, a core component for a ubiquitin ligase; Ro52;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه