Keywords: BB; bevacizumab-bevacizumab; BP; bevacizumab followed by panitumumab; CA9; carbonic anhydrase 9; CRC; colorectal cancer; DEGs; differentially expressed genes; EGFR; epidermal growth factor receptor; EPHA2; ephrin type-A receptor 2; FASN; fatty acid syntha
مقالات ISI (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: DNN; deep neural networks; k-NN; k-nearest neighbors; SVM; support vector machine; ROC curve; receiver operating characteristic curve; AUC; area under the curve; ReLU; rectified linear unit; GO; gene ontology; Circadian genes; Deep learning; Deep neural n
Keywords: APL; allosterically potentiating ligand; AD; Alzheimer's disease; Aβ; amyloid-β; ALS; amyotrophic lateral sclerosis; BCCAs; bilateral common carotid arteries stenosis; CTX; cerebral cortex; DAB; diaminobenzidine; Drp1; dynamin-related protein 1; ECTX;
Keywords: AIF; apoptosis-inducing factor; ASL; argininosuccinate lyase; ASS; argininosuccinate synthetase; AST; aspartate aminotransferase; BER; base excision repair; cGC; cyclic guanylyl cyclase; CNS; central nervous system; DRP-1; dynamin-related protein 1; EAE;
Keywords: EB1; End-Binding Protein-1; EC; endothelial cells; GEF; guanine nucleotide exchange factor; HPAEC; human pulmonary artery endothelial cells; MLC; myosin light chain; MT; microtubules; MYPT1; myosin light chain phosphatase; ns-RNA; non-specific RNA; TER; t
Keywords: ECM; extracellular matrix; FAK; focal adhesion kinase; FN; fibronectin; GAP; GTPase activating protein; GEF; guanine nucleotide exchange factor; GTPase; guanosine triphosphatase; IAC; integrin-associated adhesion complex; ILK; integrin-linked kinase; IPP;
Keywords: ATP; adenosine triphosphate; CE; capsule endoscopy; DBE; double-balloon endoscopy; FDA; Food and Drug Administration; GI; gastrointestinal; GTPase; guanosine triphosphatase; H2RAs; histamine 2 receptor antagonists; IL; interleukin; LPS; lipopolysaccharide
Keywords: Corneal endothelium; Barrier function; Actomyosin; Rho GTPase; RhoA; Rho kinase; Thrombin; HCEC; human corneal endothelial cell; GTPase; guanosine triphosphatase; GTP; guanosine triphosphate; ROCK; Rho kinase; MRCK; myotonic dystrophy kinase-related Cdc42
Keywords: BDNF; brain-derived neurotrophic factor; ECS; electroconvulsive seizure; ECT; electroconvulsive therapy; GTPase; guanidine triphosphatase; PBS; phosphate buffered saline; Electroconvulsive seizure; Autophagy; Endocytosis; Antidepressant; Neural plasticity
Keywords: Drp1; Dynamin-related protein1; GSK3β; Glucose synthase kinase 3 beta; CDK5; Cyclin dependent kinase 5; miRNA; micro ribonucleic acid; NMDAR; N-methyl-D-aspartate receptor; AMPAR; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; AD; Alzhei
Keywords: Calcium; Polarity; Trafficking; GTPase; Tension; Arabidopsis;
Keywords: Dlco; diffusing capacity of the lung for carbon monoxide; GTP; guanosine triphosphate; GTPase; guanosine triphosphatase; LAM; lymphangioleiomyomatosis; mTOR; mechanistic target of rapamycin; Rheb; Ras homolog enriched in brain; TSC; tuberous sclerosis com
Clinical findings and mutation analysis of NF1 patients in Turkey
Keywords: NF1; neurofibromatosis type 1; GTPase; Ras guanosine triphosphatase; NIH; National Institutes of Health; SSCP; single strand conformation polymorphism; HRM; High Resolution Melting Curve; CLS; café-au-lait spots; CN; cutaneous neurofibromas; LN; lisch no
Structural motifs in the RGS RZ subfamily combine to attenuate interactions with Gα subunits
Keywords: G protein signaling; RGS proteins; GTPase; Interaction specificity; PPI; Protein structure;
Neurotrophin-3 provides neuroprotection via TrkC receptor dependent pErk5 activation in a rat surgical brain injury model
Keywords: Surgical brain injury; Brain edema; Neurotrophin 3; Tropomyosin related kinase receptor C; Extracellular signal related kinase 5; SBI; Surgical brain injury; BBB; Blood brain barrier; NT-3; Neurotrophin 3; TrkC; Tropomyosin related kinase receptor C; MAPK
Seeing is understanding: Salmonella's way to penetrate the intestinal epithelium
Keywords: ARNO; adenosine diphosphate (ADP) ribosylation factor nucleotide exchange factor; BMP; bone morphogenetic protein; Cdc42; cell division control protein 42 homolog; CFU; colony forming unit; EGF; epithelial growth factor; Ets; E26 transformation-specific;
The Endosomal Protein Endotubin Is Required for Enterocyte Differentiation
Keywords: Trafficking; Endotubin; Rab; Tight Junction; Endosomes; AEC; apical endocytic complex; AP; alkaline phosphatase; CRISPR/Cas9; clustered regularly interspaced short palindromic repeats/cas9 endonuclease; EDTB; endotubin; EEA1; early endosomal antigen 1; G;
Rad GTPase Deletion Attenuates Post-Ischemic Cardiac Dysfunction and Remodeling
Keywords: calcium channel; cardioprotection; inflammation; myocardial infarction; AMI; acute myocardial infarction; EF; ejection fraction; GTPase; guanosine triphosphatase; HFrEF; heart failure with reduced ejection fraction; LAD; left anterior descending coronary
Single-molecule FRET studies on interactions between elongation factor 4 (LepA) and ribosomes
Keywords: Ribosome; Single-molecule biophysics; Translation; Fluorescence resonance energy transfer; GTPase;
Enteropathogenic Escherichia coli EspH-Mediated Rho GTPase Inhibition Results in Desmosomal Perturbations
Keywords: EPEC; Desmoglein; DSG2; Host-Pathogen Interaction; A/E; attaching and effacing; BSA; bovine serum albumin; CM; calcium and magnesium; DMEM; Dulbecco's modified Eagle medium; DSC; desmocollin; DSG; desmoglein; EPEC; enteropathogenic Escherichia coli; GE
Relationship between OPA1 and cardiolipin in mitochondrial inner-membrane fusion
Keywords: OPA1; optic atrophy 1; IM; inner membrane; OM; outer membrane; CL; cardiolipin; KO; knockout; Mfns; mitofusins; MEF; mouse embryonic fibroblast; mtDNA; mitochondrial DNA; Drp1; dynamin-related protein 1; Mff; mitochondrial fission factor; MiD49/MIEF2; mit
Formation of the Legionella-containing vacuole: phosphoinositide conversion, GTPase modulation and ER dynamics
Keywords: icm/dot; intracellular multiplication/defective organelle trafficking; LCV; Legionella-containing vacuole; PtdIns; phosphatidylinositol; PI; phosphoinositide; T4SS; type IV secretion system; Amoeba; Dictyostelium discoideum; Effector protein; Endoplasmic
Overexpression of Rac GTPase Activating Protein 1 Contributes to Proliferation of Cancer Cells by Reducing Hippo Signaling to Promote Cytokinesis
Keywords: Binucleated Cells; Large Tumor Suppressor Kinase; Pan-overexpressed; TEA Domain Transcription Factor; AURKB; aurora B kinase; ChIP; chromatin immunoprecipitation; CIN; chromosomal instability; CNL; noncancerous tissue; ECT2; epithelial cell transforming 2
Deletion of epithelial cell-specific Cdc42 leads to enamel hypermaturation in a conditional knockout mouse model
Keywords: KO; knockout mice; WT; wild type; Cdc42; Cell division cycle 42; SEM; scanning electron microscopy; EDX; energy dispersive X-ray spectroscopy; HMAI; hypomaturation; GTPase; guanosine triphosphatase; K5; keratin 5; EDJ; enamel-dentinal junction; MMP20; mat
Ras inhibitor S-trans, trans-farnesylthiosalicylic acid enhances spatial memory and hippocampal long-term potentiation via up-regulation of NMDA receptor
Keywords: S-trans; Trans-farnesylthiosalicylic acid (FTS); Spatial cognition; Long-term potentiation (LTP); NMDA receptor; Hippocampus; ACSF; artificial cerebral spinal fluid; ANOVA; analyses of variance; CaMKII; Ca2+/calmodulin-kinase II; CREB; cAMP response eleme
Direct regulation of p190RhoGEF by activated Rho and Rac GTPases
Keywords: RhoGEF; Rho guanine nucleotide exchange factors; RhoGAP; GTPase-activating proteins; DH; Dbl homology; PH; pleckstrin homology; PRG; PDZRhoGEF; TEV; Tobacco Etch Virus; His6; hexahistidine peptide; GST; glutathione S-transferase; ITC; isothermal titration
Mini-reviewA thirty-year quest for a role of R-Ras in cancer: from an oncogene to a multitasking GTPase
Keywords: R-Ras; Ras; GTPase; Oncogene; Integrins; BM; Bone marrow; C; Carboxyl; CCL21; C-C motif ligand 21; CXCL12; Cysteine X cysteine ligand 12; DC; Dendritic cells; DRG; Dorsal root ganglion; EAE; Experimental autoimmune encephalomyelitis; EC; Endothelial cells
Activation of Aplysia ARF6 induces neurite outgrowth and is sequestered by the overexpression of the PH domain of Aplysia Sec7 proteins
Keywords: 5-HT; 5-hydroxyltryptamine; PH; pleckstrin homology; ARF; ADP-ribosylation factor; GTPase; guanosine triphosphatase; GEF; guanine nucleotide exchange factor; PI(3,4,5)P3; phosphatidylinositol (3,4,5)-trisphosphate; KD; kinase-dead; ApARF6; Aplysia ARF6; A
Functional properties of LRRK2 mutations in Taiwanese Parkinson disease
Keywords: ARHGEF7; GTPase; LRRK2; p.R1441H mutation; Parkinson disease;
The Drosophila DOCK family protein Sponge is required for development of the air sac primordium
Keywords: DOCK; dedicator of cytokinesis; Spg; Sponge; Mbc; Myoblast city; Zir; Zizimin-related; Ziz; Zizimin; GTPase; guanyl triphosphatase; GAP; GTPase-activating protein; GEF; guanine nucleotide exchange factor; GDI; guanine nucleotide dissociation inhibitor; SH
Human Gpn1 purified from bacteria binds guanine nucleotides and hydrolyzes GTP as a protein dimer stabilized by its C-terminal tail
Keywords: Human Gpn1; GTPase; C-terminal tail; Protein dimer; E. coli BL-21 (DE3);
Streamlined purification of fluorescently labeled Escherichia coli phosphate-binding protein (PhoS) suitable for rapid-kinetics applications
Keywords: Phosphate-binding protein (PhoS); Fluorescence; Phosphate release; Phosphate Sensor; Rapid-kinetics; LepA/EF4; BME; β-mercaptoethanol; EDTA; ethylenediaminetetraacetic acid; GTP; Guanosine triphosphate; GTPase; Guanosine triphosphatase; HC PhoS; His-tagg
Cellular uptake and intracellular localization of poly (acrylic acid) nanoparticles in a rainbow trout (Oncorhynchus mykiss) gill epithelial cell line, RTgill-W1
Keywords: CavME; caveolae-mediated endocytosis; CMDR; CellMask Deep Red; CTb; cholera toxin B subunit; CTb-FITC; cholera toxin B subunit-fluorescein isothiocyanate; CPZ; chlorpromazine; CME; clathrin-mediated endocytosis; DAPI; 4â² 6-diamidino-2-phenylindole; ddH2
Achieving neuroprotection with LRRK2 kinase inhibitors in Parkinson disease
Keywords: COR; C-terminal of Ras; CSF; cerebral spinal fluid; DAT-1; dopamine transporter-1; ERK5; extracellular-signal-regulated kinase 5; ExAC; Exome Aggregation Consortium; GTPase; Guanosine Triphosphate Hydrolase; LoF; loss of function; LRRK2; leucine-rich repe
Azidothymidine-triphosphate impairs mitochondrial dynamics by disrupting the quality control system
Keywords: ATP; adenosine triphosphate; AZT; 3ê-azido-3ê-deoxythymidine; AZT-DP; AZT diphosphate; AZT-MP; AZT monophosphate; AZT-TP; AZT-triphosphate; calcein-AM; calcein acetoxymethyl ester; cDNA; complementary DNA; DHE; dihydroethidium; DMEM; Dulbecco's Modifi
Crystal structure of the GTPase domain and the bundle signalling element of dynamin in the GDP state
Keywords: Dynamin; GTPase; Hydrolytic cycle; X-ray structure; Endocytosis;
RhoA/ROCK signaling contributes to sex differences in the activation of human platelets
Keywords: Sex differences; Blood; Platelets; Signal transduction; GTPase
Direct inhibition of oncogenic KRAS by Bacillus pumilus ribonuclease (binase)
Keywords: RAS; Rat sarcoma; GTPase; hydrolase enzyme that can bind and hydrolyze guanosine triphosphate (GTP); Binase; Bacillus pumilus ribonuclease; ERK; extracellular signal-regulated kinases; Guanyl-preferring RNase; small G-proteins; KRAS; GAP; GEF; MAPK/ERK pa
The small GTPase Rap1 is a modulator of Hedgehog signaling
Keywords: Hedgehog; Signal transduction; Morphogenesis; GTPase; Rap1;
Dual ATPase and GTPase activity of the replication-associated protein (Rep) of beak and feather disease virus
Keywords: Beak and feather disease virus; Replication-associated protein; ATPase; GTPase
Adhesion GPCRs in immunology
Keywords: GPCR; G protein-coupled receptor; aGPCR; adhesion G protein-coupled receptor; ADGR; general adhesion GPCR name followed by class and subtype specific code; 7TM; 7 transmembrane; VLGR1; very large G protein-coupled receptor 1; ECD; extracellular domain; GP
Two-Step Forward Genetic Screen in Mice Identifies Ral GTPase-Activating Proteins as Suppressors of Hepatocellular Carcinoma
Keywords: Sleeping Beauty; Liver Cancer; RalGAPs; Kinase Inhibitor; CCG; candidate cancer genes; CIS; common transposon insertion site; gCIS; gene-centric common transposon insertion site-calling method; GTPase; guanosine triphosphatase; HBsAg; hepatitis B surfac
Rab11a Is Essential for Lamellar Body Biogenesis in the Human Epidermis
Keywords: Cer; ceramide; Ctrl; control; GTP; guanosine triphosphate; GTPase; GTP hydrolase; LB; lamellar body; LRO; lysosome-related organelle; RHE; reconstructed human epidermis; shRNA; short hairpin RNA; TEWL; transepidermal water loss; TGN; trans-Golgi network;
The store-operated Ca2Â + entry-mediated signaling is important for cancer spread
Keywords: bFGF; basic fibroblast growth factor; CRAC; calcium release-activated channels; CAD; CRAC activation domain;; CaM kinase II; Ca2Â +/calmodulin-dependent protein kinase II; ER; endoplasmic reticulum; EGF; epidermal growth factor; ECM; extracellular matrix;
Regulation of Mitofusin1 by Mahogunin Ring Finger-1 and the proteasome modulates mitochondrial fusion
Keywords: BN-PAGE; blue native polyacrlamide gel electrophoresis; CCCP; carbonyl cyanide m-chlorophenyl hydrazone; CM-H2DCFDA; chloromethyl derivative of 2â²,7â²-dichlorodihydrofluorescein diacetate; Drp1; dynamin related protein 1; DTT; 1,4-dithiothreitol; ER; e
Two conserved amino acids of juxtaposed domains of a ribosomal maturation protein CgtA sustain its optimal GTPase activity
Keywords: CgtA; Ribosome; Obg; GTPase; Point mutationCgtA, CaulobactorGTPase A or common GTPase A; Obg, spoOB associated GTP binding protein; CgtAvc, CgtA of Vibrio cholerae; ppGpp, Guanosine 5′-diphosphate 3′-diphosphate; DM, double mutant
Functional studies of TcRjl, a novel GTPase of Trypanosoma cruzi, reveals phenotypes related with MAPK activation during parasite differentiation and after heterologous expression in Drosophila model system
Keywords: Trypanosoma cruzi; GTPase; Rjl; Metacyclogenesis; Differentiation
RLIP76 regulates Arf6-dependent cell spreading and migration by linking ARNO with activated R-Ras at recycling endosomes
Keywords: Ras; Migration; Spreading; Recycling endosome; Small GTPase; Arf; ADP ribosylation factor; ArfGAP; Arf GTPase activating protein; ArfGEF; Arf guanine nucleotide exchange factor; ECM; extracellular matrix; GTP; guanosine triphosphate; GTPase; GTP hydrolyzi
Interaction between Bacillus subtilis YsxC and ribosomes (or rRNAs)
Keywords: P-loop, phosphate-binding loop; GMPPNP, guanylyl-imidodiphosphate; rRNA, ribosomal RNA; Tm, melting temperature; TSA, thermal shift assay; DTT, dithiothreitolYsxC; GTPase; Ribosome binding; Bacillus subtilis
MgcRacGAP inhibition stimulates JAK-dependent STAT3 activity
Keywords: GAP; GTPase Activating Protein; GTPase; guanosine triphosphatase; HEK293 SIE-Luc; HEK293 GloResponse SIE Luc2P Hygro cells; IL-6; interleukin-6; MgcRacGAP; male germ cell Rac GTPase-activating protein; MINC1; MgcRacGAP inhibitor compound 1; STAT3; signal