دانلود مقالات ISI درباره Gtpγs + ترجمه فارسی

تجزیه و تحلیل تنظیمات محصول طبیعی گیرنده های کانابینوئید در درمان بیماری های انسانی

Analysis of natural product regulation of cannabinoid receptors in the treatment of human disease

Keywords: AC; adenyl cyclase; AD; Alzheimer's disease; 2-AG; 2-arachidonoylglycerol; ABHD6; α,β hydrolase 6; AEA; arachidonylethanolamide/anandamide; ALS; amyotrophic lateral sclerosis; BBB; blood brain barrier; cAMP; cyclic adenosine monophosphate; CBD; cannabid

دانلود رایگان متن کامل مقاله ISI 81 صفحه سال انتشار : 2017 سفارش ترجمه

بررسی ویژگی های گیرنده و عملکردی همورسین (1-7)

Investigation of receptor binding and functional characteristics of hemopressin(1-7)

Keywords: AM251; 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-(1-piperidyl)pyrazo-le-3-carboxamide; BSA; bovine serum albumin; DAMGO; [d-Ala2, N-MePhe4, Gly-ol]-enkephalin; DIEA; diisopropylethylamine; DMF; dimethylformamide; EGTA; ethylene glycol-bis(2-amino

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

فعالیت پتروشیمی سیتوکروم عصبی و اختلال افسردگی: سایتها و مکانیزم های مربوطه

Neuronal cytochrome P450 activity and opioid analgesia: relevant sites and mechanisms

Keywords: ANOVA; analysis of variance; CPR; cytochrome P450 reductase; DAMGO; [D-Ala2, N-Me-Phe4, Gly5-ol]-enkephalin acetate; GTPγS; guanosine 5′-O-(3-thiotriphosphate) tetralithium salt; icv; intracerebroventricular; Null; neuronal cytochrome P450 reductase de

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

خصوصیات مولکولی الکساندولین به عنوان یک لیگاند بالقوه هدفمند کننده هتومر گیرنده های متیل دلتا

Molecular characterization of eluxadoline as a potential ligand targeting mu-delta opioid receptor heteromers

Keywords: μOR-δOR heteromer; Anti-diarrhea; Eluxadoline; Loperamide; Irritable bowel syndrome; GI; gastrointestinal; IBS-d; irritable bowel syndrome with diarrhea; μOR; mu opioid receptor; δOR; delta opioid receptor; βgal; beta-galactosidase; GTPγS; guanosine

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

متکاتینون های متناظر در متابولیسم های گیرنده و گیرنده تفاوت دارند

Substituted methcathinones differ in transporter and receptor interactions

Keywords: LSD; lysergic acid diethylamide; METH; (+)methamphetamine; MDMA; 3,4-methylenedioxymethylamphetamine; MDPV; 3,4-methylenedioxypyrovalerone; mephedrone; 4-methyl-N-methylcathinone; methylone; 3,4-methylenedioxy-N-methylcathinone; 4-FMC; 4-fluoromethcathino

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2013 سفارش ترجمه

C60 fullerenes disrupt cellular signalling leading to TRPC4 and TRPC6 channels opening by the activation of muscarinic receptors and G-proteins in small intestinal smooth muscles

Keywords: mICAT; muscarinic cation current; TRP channels; transient receptor potential cation channels; TRPC4 channel; Canonical transient receptor potential cation channel 4; C60NPs; C60 fullerene nanoparticles; GTPγS; guanosine 5′-triphosphate sodium salt hydr

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

7β-Methyl substituent is a structural locus associated with activity cliff for nepenthone analogues

Keywords: WHO; World Health Organization; nor-BNI; norbinaltorphimine; GNTI; 5′-guanidinonaltrindole; GTPγS; guanosine 5′-O-[γ-thio]-triphosphate; HPLC; high performance liquid chromatography; 7β-Methyl-nepenthone analogues; KOR ligands; Concept of hybridiza

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Induction of oxidative stress by long-term treatment of live HEK293 cells with therapeutic concentration of lithium is associated with down-regulation of δ-opioid receptor amount and function

Keywords: AAS; atomic absorption spectroscopy; Ab; antibody; BD; bipolar disorder; DADLE; (2-d-alanine-5-d-leucine)-enkephalin = Tyr-d-Ala-Gly-Phe-d-Leu; DCF; 2′,7′-dichlorofluorescein; DCFH-DA; 2′,7′-dichlorofluorescin diacetate (synonym dichlorodihydr

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Pharmacological characterization of novel synthetic opioids (NSO) found in the recreational drug marketplace

Keywords: Analgesia; Butyrylfentanyl; Mu-opioid receptor; MT-45; U-47700; DAMGO; [D-Ala2,N-MePhe4,Gly-ol]-enkephalin; DPDPE; [D-Pen2, D-Pen5]-enkephalin; DOR-1; delta-opioid receptor; GTPγS; guanosine 5′-O-[gamma-thio]triphosphate; KOR-1; kappa-opioid receptor;

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Effective G-protein coupling of Y2 receptors along axonal fiber tracts and its relevance for epilepsy

Keywords: NPY; Y2 receptors; Schaffer collaterals; Stria terminalis; GTPγS; G-protein coupling; Kainic acid; Epilepsy;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Kynurenic acid and its analogue can alter the opioid receptor G-protein signaling after acute treatment via NMDA receptor in rat cortex and striatum

Keywords: KYNA; Opioid receptor; [35S]GTPγS binding; G-protein; MK-801; 3-NLT; 3-nitro-l-tyrosine; CNS; central nerve system; CSF; cerebrospinal fluid; BBB; blood-brain barrier; DAMGO; Tyr-D-Ala-Gly-(NMe)Phe-Gly-ol; DOPr; δ opioid peptide receptor; EGTA; ethylene

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Novel multifunctional dopamine D2/D3 receptors agonists with potential neuroprotection and anti-alpha synuclein protein aggregation properties

Keywords: TPP; triphenylphosphine; NaHMDS; sodium bis(trimethylsilyl)amide; DIBALH; diisobutylaluminium hydride; TBS; tert-butyldimethylsilyl; TBDMSCl; tert-butyl(chloro)dimethylsilane; PCC; pyridinium chlorochromate; TBAF; tetra-n-butylammonium fluoride; HMDS; hex

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Tricyclic pyrazoles. Part 8. Synthesis, biological evaluation and modelling of tricyclic pyrazole carboxamides as potential CB2 receptor ligands with antagonist/inverse agonist properties

Keywords: Tricyclic pyrazoles; Synthesis; Cannabinoid receptors; CB2 antagonism; Molecular modelling; Δ9-THC; Δ9-Tetrahydrocannabinol; 2-AG; 2-Arachidonoylglycerol; CB1; cannabinoid receptor type 1; CB2; cannabinoid receptor type 2; CNS; Central nervous system; T

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Clostridium difficile toxin B inhibits the secretory response of human mast cell line-1 (HMC-1) cells stimulated with high free-Ca2+ and GTPγS

Keywords: Human mast cell line-1 (HMC-1); Membrane capacitance; Whole-cell patch-clamp; GTPγS; Clostridium difficile toxin B (TcdB); Hexosaminidase;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Intrinsic relative activities of κ opioid agonists in activating Gα proteins and internalizing receptor: Differences between human and mouse receptors

Keywords: 12epiSalA; 12-epi-Salvinorin A; 7TMR; seven-transmembrane domain receptor; dynorphin A; (1‐17) (H‐Tyr‐Gly‐Gly‐Phe‐Leu‐Arg‐Arg‐Ile‐Arg‐Pro‐Lys‐Leu‐Lys‐Trp‐Asp‐Asn‐Gln‐OH); EKC; ethylketocyclazocine; EOM-SalB; ethoxymet

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Identification of amino acids that are selectively involved in Gi/o activation by rat melanin-concentrating hormone receptor 1

Keywords: cAMP; cyclic AMP; DMR; dynamic mass redistribution; GPCR; G-protein-coupled receptor; GTPγS; guanosine 5′-O-[gamma-thio]triphosphate; i1; first intracellular; i2; second intracellular; i3; third intracellular; MCH; melanin-concentrating hormone; MCHR;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Structure-kinetics relationships of Capadenoson derivatives as adenosine A1 receptor agonists

Keywords: Residence time; Structure-affinity relationships; Structure-kinetics relationships; Adenosine A1 receptor; Extracellular loops; ADA; adenosine deaminase; Ac; acetyl; BCA; bicinchoninic acid; BEDROC; Boltzmann-enhanced discrimination of receiver-operating

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Stimulatory effect of pituitary adenylate cyclase-activating polypeptide 6-38, M65 and vasoactive intestinal polypeptide 6-28 on trigeminal sensory neurons

Keywords: AC; adenylate cyclase; [Ca2+]i; intracellular free calcium concentration; cAMP; cyclic adenosine 3′,5′-monophosphate; CGRP; calcitonin gene-related peptide; CHO; Chinese hamster ovary cell line; CPM; count per minute; DAG; diacylglycerol; D-MEM; Dulbe

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Pathophysiology of the hepoxilins

Keywords: AA; arachidonic acid; AMG9810; (2E)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-dimethylethyl)phenyl]-2-propenamide; Apaf-1; Apoptotic protease activating factor 1; BAPTA; 1,2-Bis(o-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid; CCCP; carbonyl cya

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Delta FosB and AP-1-mediated transcription modulate cannabinoid CB1 receptor signaling and desensitization in striatal and limbic brain regions

Keywords: AMYG; amygdala; BSA; bovine serum albumin; CaMKIIα; calcium/calmodulin-dependent protein kinase II; CB1R; cannabinoid type 1 receptor; CBLM; cerebellum; CP55,940; (−)-cis-3-[2-hydroxy-4-(1,1-dimethylheptyl)phenyl]-trans-4-(3-hydroxypropyl)cyclohexanol;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Azathioprine desensitizes liver cancer cells to insulin-like growth factor 1 and causes apoptosis when it is combined with bafilomycin A1

Keywords: ERK; extracellular signal-regulated kinase; TSC-2; tuberous sclerosis 2 protein; mTOR; mammalian target of rapamycin; IRS; insulin receptor substrate; PI3K; phosphoinositide-3-kinase; AKT; protein kinase B; MAPK; mitogen-activated protein kinase; FOXO1; f

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Uliginosin B presents antinociceptive effect mediated by dopaminergic and opioid systems in mice

Keywords: 13C RMN; carbon nuclear magnetic resonance; 1H RMN; proton nuclear magnetic resonance; ANOVA; analysis of variance; CGEN; Conselho de Gestão do Patrimônio Genético; CIOMS; Council for International Organization of Medical Sciences International; COD; c

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Signal transduction pathway activity compensates dopamine D2/D3 receptor density changes in Parkinson's disease: a preliminary comparative human brain receptor autoradiography study with [3H]raclopride and [35S]GTPγS

Keywords: ARG; autoradiography; DAT; dopamine transporter; GTPγS; guanosine 5′-O-[gamma-thio]triphosphate; l-DOPA; L-3,4-dihydroxyphenylalanine; MAO-B; Monoamine oxidase B; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; OD; optical density; PD; Parkinson's

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Surface masking shapes the traffic of the neuropeptide Y Y2 receptor

Keywords: AcLeu; human neuropeptide Y(24-36) acetyl-Leu(28 31); BIBP326; R-N 2-(diphenylacetyl)-N-(4-hydroxyphenyl)methyl-arginineamide; BIIE0246; N-[(1S)-4-[(aminoiminomethyl)amino]-1-[([2-(3,5-dioxo-1,2-diphenyl-1,2,4-triazolidin-4-yl)ethyl]amino)carbonyl]butyl

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Uniform assessment and ranking of opioid Mu receptor binding constants for selected opioid drugs

Keywords: MOR; Mu opioid receptor; DOR; delta opioid receptor; KOR; kappa opioid receptor; DAMGO; (d-Ala2, N-MePhe4, Gly-ol)-enkephalin; GPCR; G-protein coupled receptors; FDA; Food and Drug Administration; Ki; equilibrium dissociation constant for the test compoun

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Residual effects of focal brain ischaemia upon cannabinoid CB1 receptor density and functionality in female rats

Keywords: AM251; N-(Piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1-H-pyrazole-3-carboxamide; CA1-CA3; cornu ammonis 1-cornu ammonis 3 pyramidal cell layer; CB; cannabinoid; CP55,940; (−)-cis-3-[2-hydroxy-4-(1,1-dimethylheptyl)phenyl]-trans

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Diffusion and light-dependent compartmentalization of transducin

Keywords: Gt1; rod G protein transducin; Gαt1; rod transducin α-subunit; PDE6; photoreceptor phosphodiesterase-6; R*; photoexcited rhodopsin; FRAP; fluorescence recovery after photobleaching; ROS (OS); rod outer segment(s); RIS (IS); rod inner segment(s); GTPγS;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Transactivation of epidermal growth factor receptor by enhanced levels of endogenous angiotensin II contributes to the overexpression of Giα proteins in vascular smooth muscle cells from SHR

Keywords: ACE; angiotensin I converting enzyme; DOCA-salt rats; deoxycorticosterone acetate-salt hypertensive rats; AVP; arginine-vasopressin; DPI; diphenyleneiodonium; ERK1/2; extracellular regulated kinase 1 and 2; Ang II; angiotensin II; AT1; angiotensin

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Mimicking nature's noses: From receptor deorphaning to olfactory biosensing

Keywords: BAW; bulk acoustic wave; BRET; bioluminescence resonance energy transfer; cVA; 11-cis-vaccenyl acetate; cAMP; cyclic adenosine monophosphate; cGMP; cyclic guanosine monophosphate; CNG; cyclic nucleotide gated; EAG; electroantennagram; EOG; electroolfactog

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2011 سفارش ترجمه

Palmitoylation modification of Gαo depresses its susceptibility to GAP-43 activation

Keywords: GAP-43; growth associated protein-43; Gαo; α subunit of heterotrimeric Go protein; GTPγS; guanosine-5′-O-(3-thiotriphosphate); p-PDM; N,N′-1,4-phenylenedimaleimide; IPTG; isopropyl-β-d-thiogalactoside; GAP-43; Gαo; Palmitoylation; GTPγS binding

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Development of fetal brain renin-angiotensin system and hypertension programmed in fetal origins

Keywords: ACE; angiotensin converting enzyme; ACTH; adrenocorticotropic hormone; Ang; angiotensin; AP; area postrema; AT1R; angiotensin II receptor subtype 1; AT2R; angiotensin II receptor subtype 2; ATIP; AT2R-interacting protein; AVP; arginine vasopressin; BBB; b

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2009 سفارش ترجمه

Differential coupling of the human cannabinoid receptors hCB1R and hCB2R to the G-protein Gαi2β1γ2

Keywords: AM 251; 6-iodopravadoline; AM 630; (6-iodo-2-methyl-1-[2-4(morpholinyl)-ethyl]-[1H-indol-3-yl]-(4-methoxyphenyl)methan-none); β2ARβ; 2-adrenoceptor; CP 55, 940; [(-)-cis-3-[2-hydroxy-4-(1,1-dimethylheptyl)phenyl]-trans-4-(3-hydroxypropyl)cyclohexanol];

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Purification and characterization of transducin from capybara Hydrochoerus hydrochaeris

Keywords: PDE6; retinal rod type VI cGMP phosphodiesterase; GMPPNP; β,γ-imido-guanosine 5'-triphosphate; GTPγS; guanosine 5'-O-(3-thiotriphosphate); Kd; dissociation constant; R; rhodopsin; R⁎; photoactivated rhodopsin or metarhodopsin II; ROS; rod outer segme

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Rats with high or low sociability are differently affected by chronic variable stress

Keywords: sucrose intake; anxiety; depression; anhedonia; single housing; ANOVA; analysis of variance; CRF; corticotropin-releasing factor; CVS; chronic variable stress; DA; dopamine; DOPAC; dihydroxyphenylacetic acid; D2; dopamine receptor subtype 2; EDTA; ethylen

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

A simple and rapid synthesis of nucleotide analogues containing a phosphorothioate moiety at the terminal position of the phosphate chain

Keywords: Phosphorothioates; Nucleotide analogues; Phosphorimidazolides; Chemical synthesis; ADPβS; adenosine 5′-(2-thiodiphosphate); GDPβS; guanosine 5′-(2-thiodiphosphate); IDPβS; inosine 5′-(2-thiodiphosphate); UDPβS; uridine 5′-(2-thiodiphosphate);

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2007 سفارش ترجمه

Dopamine D2 receptor-mediated G protein activation assessed by agonist-stimulated [35S]guanosine 5′-O-(γ-thiotriphosphate) binding in rat striatal membranes

Keywords: CHO; Chinese hamster ovary; EC50; the concentration eliciting the half-maximal stimulation; %Emax; the percent maximal increase above the basal binding; G protein; guanine nucleotide-binding regulatory protein; GTPγS; guanosine 5′-O-(γ-thiotriphosphat

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Spinal nerve ligation does not alter the expression or function of GABAB receptors in spinal cord and dorsal root ganglia of the rat

Keywords: neuropathic; pain; allodynia; ANOVA; analysis of variance; DRG; dorsal root ganglia; GTPγS; guanosine-5′-(γ-O-thio)triphosphate; L; lumbar; PB; phosphate buffer; PBS; phosphate-buffered saline;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

A bifunctional Gαi/Gαs modulatory peptide that attenuates adenylyl cyclase activity

Keywords: Adenylyl cyclase; Biosensors; G-proteins; Phage display; Signal transduction; Surface plasmon resonance; AC; adenylyl cyclase [E.C. 4.6.1.1]; AMP; adenosine monophosphate; cAMP; cyclic AMP; FITC; fluorescein isothiocyanate; FSK; forskolin; GDI; guanine nu

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2005 سفارش ترجمه

Inhibition of phospholipase C-independent exocytotic responses in rat peritoneal mast cells by U73122

Keywords: U73122; Mast cells; Exocytosis; Phospholipase C; Streptolysin O; GTPγS; Mastoparan; G-protein;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

Identification and characterisation of a novel splice variant of the human CB1 receptor

Keywords: 2-AG; 2-arachidonoylglycerol; CP55940; (−)-cis-3-[2-hydroxy-4-(1,1-dimethylheptyl)phenyl]-trans-4-(3-hydroxypropyl)cyclohexanol; WIN55,212-2; R(_)-[2,3-di-hydro-5-methyl-3-[(morpholinyl)methyl]pyrrolo[1,2,3-de]-1,4-benz-oxazinyl]-(1-naphthalenyl)-methan

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

Adenosine reverses the stimulatory effect of angiotensin II on the renal Na+-ATPase activity through the A2 receptor

Keywords: Ado; Adenosine; Ang II; angiotensin II; ATP; adenosine triphosphate; cAMP; Adenosine 3′,5′-cyclic monophosphate; CTX; Cholera toxin; DMPX; 3,7-dimethyl-1-propargylxanthine; DPCPX; 8-Cyclopentyl-1,3-dipropylxanthine; EDTA; ethylenediaminetetraacetic ac

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Palmitoylation regulates GDP/GTP exchange of G protein by affecting the GTP-binding activity of Goα

Keywords: GTPγS; guanosine-5′-O-(3-thiotriphosphate); HB; hypocrellin B; GPCR; G-protein-coupled receptor; G protein; Palmitoylation; GTP-binding activity; Conformation change; Signal transduction;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

Chronic caffeine or theophylline intake during pregnancy inhibits A1 receptor function in the rat brain

Keywords: adenosine A1 receptor; methylxanthines; gestation; Gi-proteins; desensitization; AC; adenylyl cyclase; ANOVA; analysis of variance; A1R; adenosine A1 receptors; CHA; N6-cyclohexyladenosine; GTPγS; guanosine-5′-O(3-thiotriphosphate) tetralithium salt; S

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

Neuronal nitric oxide modulates morphine antinociceptive tolerance by enhancing constitutive activity of the μ-opioid receptor

Keywords: DAMGO; [D-Ala2, N-MePhe4, Gly-ol5]enkephalin; GDP; guanosine diphosphate; GPCR; G-protein-coupled receptor; GppNHp; 5′guanylylimidodiphosphate; GTPγS; guanosine5′-G-(3-thio)triphosphate; NaCl; sodium chloride; NO; nitric oxide; Constitutive activity;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Stimulation of the proximal tubule Na+-ATPase activity by adenosine A2A receptor

Keywords: Na+-ATPase; Adenosine; Adenosine receptor; Proximal tubule; PKA; EDTA; ethylenediaminetetraacetic acid; HEPES; (N-2-hydroxyethylpiperazine N′-2-ethanesulfonic acid); Tris; tris(trishydroxymethyl)-aminomethane; ATP; adenosine triphosphate (sodium salt);

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Gα selectivity and inhibitor function of the multiple GoLoco motif protein GPSM2/LGN

Keywords: BODIPY®; 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene; GDI; guanine nucleotide dissociation inhibitor; GL1, GL2, GL3, GL4; individual GPSM2 GoLoco motifs; GoLoco; Gαi/o-Loco interaction; GPSM2; G-protein signalling modulator 2; GST; glutathione S-transf

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Interaction of μ-opioid receptor agonists and antagonists with the analgesic effect of buprenorphine in mice

Keywords: % MPE; % maximal possible effect; GTPγS; guanosine-5′-O-(γ-thio)-triphosphate; ORL1-receptor; orphan receptor-like receptor 1; SEM; standard error of mean; Buprenorphine; μ-Opioid receptor; μ-Opioid antagonists; Interactions; Opioid rotation; Tail-f

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2005 سفارش ترجمه

Regulation of ASAP1 by phospholipids is dependent on the interface between the PH and Arf GAP domains

Keywords: DH; dbl homology; FRET; fluorescence resonance energy transfer; GAP; GTPase-activating protein; GTPγS; guanosine 5′-O-(3-thiotriphosphate); NHS; N-hydroxysuccinimide; PA; phosphatidic acid; PdZA; a chimeric protein consisting of the PH domain of PLC δ

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2005 سفارش ترجمه

The role of Rho GTPases and SNAREs in mediator release from granulocytes

Keywords: Neutrophils; Eosinophils; Mast cells; Respiratory burst; Exocytosis; Granules; ATP; adenosine triphosphate; GAP; GTPase-activating protein; GEF; guanine nucleotide exchange factor; GTP; guanosine triphosphate; GTPγS; guanosine 3′-thiotriphosphate; GTPa

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2005 سفارش ترجمه