Keywords: فاکتور تبادل نوکلئوتید گوانین; OLG; oligodendrocyte; CNS; central nervous system; SC; Schwann cell; PNS; peripheral nervous system; MBP; myelin basic protein; PLP; proteolipid protein; P0/MPZ; myelin protein zero; EAE; experimental allergic encephalomyelitis; MS; multiple sclerosis; CN
مقالات ISI فاکتور تبادل نوکلئوتید گوانین (ترجمه نشده)
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Keywords: فاکتور تبادل نوکلئوتید گوانین; ABA; abscisic acid; ABI; ABA-insensitive; AIM/LIR; ATG8-interacting motif/LC3-interacting region; AREB/ABFs; ABRE-binding protein/ABRE-binding factor; ARM; armadillo repeat; Atg8; autophagy-related 8; BAG6; BCL-2 associated athanogene 6; BiPs; lumenal bin
Keywords: فاکتور تبادل نوکلئوتید گوانین; AC; adenylyl cyclase; ALG-2; apoptosis-linked gene 2 product; Alix; ALG-2-interacting protein X; Bcl10; B-cell lymphoma/leukemia protein 10; CaM; calmodulin; CaM-BD; CaM-binding domain; CaM-BP; CaM-binding protein; CARD; caspase-recruitment domain; Carma1
Keywords: فاکتور تبادل نوکلئوتید گوانین; AD; Alzheimer Disease; DS; Down Syndrome; Aβ; amyloid-β; HSA21; Chromosome 21; APP; Amyloid precursor protein; BACE1/2; β-site APP cleaving enzyme 1/2; βCTF; β carboxyl-terminal fragment; PSEN1; presenilin 1; APPL1; adaptor protein containing pleckst
Keywords: فاکتور تبادل نوکلئوتید گوانین; S1P; sphingosine-1-phosphate; S1P2; sphingosine-1-phosphate receptor 2; APC; adenomatous polyposis coli; FAK; focal adhesion kinase; Lm; Listeria monocytogenes; Stm; Salmonella typhimurium; RSV; respiratory syncytial virus; GEF; guanine nucleotide exchang
Keywords: فاکتور تبادل نوکلئوتید گوانین; EB1; End-Binding Protein-1; EC; endothelial cells; GEF; guanine nucleotide exchange factor; HPAEC; human pulmonary artery endothelial cells; MLC; myosin light chain; MT; microtubules; MYPT1; myosin light chain phosphatase; ns-RNA; non-specific RNA; TER; t
Keywords: فاکتور تبادل نوکلئوتید گوانین; ECM; extracellular matrix; FAK; focal adhesion kinase; FN; fibronectin; GAP; GTPase activating protein; GEF; guanine nucleotide exchange factor; GTPase; guanosine triphosphatase; IAC; integrin-associated adhesion complex; ILK; integrin-linked kinase; IPP;
Keywords: فاکتور تبادل نوکلئوتید گوانین; CAPRI; Ca2+-promoted RAS inactivator; CRMP-2; collapsin response mediator protein-2; CSRD; cysteine/serine-rich domain; CTD; C-terminal domain; ERK; extracellular signal-regulated kinase; FTI; farnesyltransferase inhibitor; FAK1; focal adhesion kinase 1;
Keywords: فاکتور تبادل نوکلئوتید گوانین; CERT; ceramide transfer protein; CETP; cholesteryl ester transfer protein; ER; endoplasmic reticulum; FABP; fatty acid-binding protein; FFAT; diphenylalanine in an acidic tract; GAP; GTPase-activating protein; GEF; guanine nucleotide exchange factor; GLs;
Keywords: فاکتور تبادل نوکلئوتید گوانین; AC; adenylyl cyclase; CCK; cholecystokinin; CFTR; cystic fibrosis transmembrane regulator; CREBs; cAMP response element binding proteins; EGF; epidermal growth factor; Epac; Exchange protein directly activated by cAMP; GDP; guanosine diphosphate; GEF; gua
Keywords: فاکتور تبادل نوکلئوتید گوانین; 4E-BP1; eIF4E binding protein 1; 5â²-UTR; 5â²-untranslated region; AMPK; AMP-activated protein kinase; eIF; eukaryotic initiation factor; GCN2; general-control nonderepressible; GEF; guanine nucleotide exchange factor; GSK-3; glycogen synthase kinase-3;
Keywords: فاکتور تبادل نوکلئوتید گوانین; APC; adenomatous polyposis coli; bFGF; basic fibroblast growth factor; Ca2Â +i; intracellular calcium; Ca2Â +o; extracellular calcium; CaSR; calcium sensing receptor; CDX-2; caudal type homeobox 2; EGF; epidermal growth factor; ERK; extracellular-signal-r
Overexpression of ST5, an activator of Ras, has no effect on β-cell proliferation in adult mice
Keywords: فاکتور تبادل نوکلئوتید گوانین; Diabetes; β-cell proliferation; ST5 (Suppression Of Tumorigenicity 5); Ras/ERK signaling; ST5; Suppression of Tumorigenicity 5; GEF; Guanine Nucleotide Exchange Factor; ST5 OE; ST5-overexpressing; STZ; streptozotocin; MODY; Maturity Onset Diabetes of the
Functions and mechanisms of microRNA-31 in human cancers
Keywords: فاکتور تبادل نوکلئوتید گوانین; 3â²-UTRs3â²; -untranslated regions; ADC; Adenocarcinoma; BC; Breast cancer; BER; base excision repair; CDK4; cyclin-dependent kinase 4; CRC; Colorectal cancer; CRT; chemo-radiation therapy; C-TAD; COOH terminal transactivation domain; DHR1; dihydrorhoda
Phosphorylation of Ser-525 in βPix impairs Nox1-activating ability in Caco-2 cells
Keywords: فاکتور تبادل نوکلئوتید گوانین; Nox1; Superoxide; βPix; Phosphorylation; Rac; Caco-2 cell; GEF; guanine nucleotide exchange factor; Nox; NADPH oxidase; EGF; epidermal growth factor; NGF; nerve growth factor; FGF; fibroblast growth factor; GBD; GIT1-binding domain; G-Sepharose; glutath
MeHg affects the activation of FAK, Src, Rac1 and Cdc42, critical proteins for cell movement in PDGF-stimulated SH-SY5Y neuroblastoma cells
Keywords: فاکتور تبادل نوکلئوتید گوانین; MeHg; methylmercury; Ca2+; Calcium; Rac1; ras related C3 botulinum toxin substrate 1; Cdc42; cell division control protein 42 homolog; RhoA; ras homolog gene family member A; GD; gestation day; PND; postnatal day; FAK; focal adhesion kinase; p-FAKY397; FA
Functional characterization of an apple (Malus x domestica) LysM domain receptor encoding gene for its role in defense response
Keywords: فاکتور تبادل نوکلئوتید گوانین; CERK; chitin elicitor receptor kinase; PRR; pattern recognition receptor; GST; glutathione S-transferase; PAMP; pathogen-associated molecular patterns; PTI; PAMP-triggered immunity; ROS; reactive oxygen species; ETS; effector-triggered susceptibility; ETI
PDZ-RhoGEF Is a Signaling Effector for TROY-Induced Glioblastoma Cell Invasion and Survival
Keywords: فاکتور تبادل نوکلئوتید گوانین; GBM; glioblastoma multiforme; PRG; PDZ-RhoGEF; NF-κB; nuclear factor kappa B; GEF; guanine nucleotide exchange factor;
Effects of the NO/soluble guanylate cyclase/cGMP system on the functions of human platelets
Keywords: فاکتور تبادل نوکلئوتید گوانین; Platelet inhibition; Phosphoproteome; cGMP-dependent protein kinase/PKG; Small GTP-binding proteins; G proteins; NO; nitric oxide; PKA; protein kinase A; PKG; protein kinase G; PDE; phosphodiesterase; sGC; soluble guanylate cyclase; GPCR; G-protein couple
FLCN: The causative gene for Birt-Hogg-Dubé syndrome
Keywords: فاکتور تبادل نوکلئوتید گوانین; AEC; alveolar epithelial type II cell; AKT; protein kinase B; AMPK/Ampk; 5â²-AMP activated protein kinase; AMPKα (also AAK-2); AMPKα subunit; ATP; adenosine triphosphate; Bcl-2; B-cell lymphoma 2; BHD; Birt-Hogg-Dubé; BAT; brown adipose tissue; C. ele
EphBs and ephrin-Bs: Trans-synaptic organizers of synapse development and function
Keywords: فاکتور تبادل نوکلئوتید گوانین; βGal; β-Galactosidase; Aβ; amyloid-β; Abl; Abelson murine leukemia viral oncogene homolog; AD; Alzheimer's disease; AMPAR; α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; APP; amyloid precursor protein; BLA; basolateral amygdala; CaMKI
Up-regulation of NSP3 by Oligomeric Aβ Accelerates Neuronal Death Through Cas-independent Rap1A Activation
Keywords: فاکتور تبادل نوکلئوتید گوانین; aa; amino acid; Aβ; β-amyloid; AD; Alzheimer's disease; APP; amyloid precursor protein; CBD; Cas-binding domain; DIV; days in vitro; GEF; guanine nucleotide exchange factor; HFIP; 1,1,1,3,3,3-hexafluoro-2-propanol; NBD; NSP3-binding domain; NSP3; nove
Regulation of vascular tone homeostasis by NO and H2S: Implications in hypertension
Keywords: فاکتور تبادل نوکلئوتید گوانین; ADRF; adipocyte-derived relaxing factor; AE; anion exchanger; ATP; adenosine triphosphate; BH4; tetrahydrobiopterin; BKCa; big conductance Ca2+-sensitive K+ channel; CaM; calmodulin; cAMP; cyclic adenosine monophosphate; CAT; cysteine aminotransferase; CB
The small GTPase, Rab27, and its effectors and regulators participate in granule exocytosis by parotid acinar cells
Keywords: فاکتور تبادل نوکلئوتید گوانین; Slp; synaptotagmin-like protein; Slac2; Slp homolog lacking C2 domains; SHD; synaptotagmin-like protein homology domain; GST; glutathione S-transferase; IPR; isoproterenol; SLO; streptolysin O; GAP; GTPase activating protein; GEF; guanine nucleotide excha
Activation of Aplysia ARF6 induces neurite outgrowth and is sequestered by the overexpression of the PH domain of Aplysia Sec7 proteins
Keywords: فاکتور تبادل نوکلئوتید گوانین; 5-HT; 5-hydroxyltryptamine; PH; pleckstrin homology; ARF; ADP-ribosylation factor; GTPase; guanosine triphosphatase; GEF; guanine nucleotide exchange factor; PI(3,4,5)P3; phosphatidylinositol (3,4,5)-trisphosphate; KD; kinase-dead; ApARF6; Aplysia ARF6; A
The Drosophila DOCK family protein Sponge is required for development of the air sac primordium
Keywords: فاکتور تبادل نوکلئوتید گوانین; DOCK; dedicator of cytokinesis; Spg; Sponge; Mbc; Myoblast city; Zir; Zizimin-related; Ziz; Zizimin; GTPase; guanyl triphosphatase; GAP; GTPase-activating protein; GEF; guanine nucleotide exchange factor; GDI; guanine nucleotide dissociation inhibitor; SH
Arhgef1 is expressed in cortical neural progenitor cells and regulates neurite outgrowth of newly differentiated neurons
Keywords: فاکتور تبادل نوکلئوتید گوانین; Arhgef1; Rho guanine nucleotide exchange factor 1; GEF; guanine nucleotide exchange factor; RhoA; Ras homolog gene family, member A; Rac1; Ras-related C3 botulinum toxin substrate 1; Cdc42; cell division control protein 42; DAPI; 4â²,6-diamidino-2-phenyl
A newly identified Rab-GDI paralogue has a role in neural development in amphibia
Keywords: فاکتور تبادل نوکلئوتید گوانین; 1R; first eukaryotic genome duplication; 2R; second eukaryotic genome duplication; AMO; antisense morpholino; A-P; anterior-posterior; cDNA; complementary DNA; DNA; deoxyribonucleic acid; GAP; GTPase activating protein; GDI; guanidine dissociation inhibit
Polymorphisms in DENND1B gene are associated with asthma and atopy phenotypes in Brazilian children
Keywords: فاکتور تبادل نوکلئوتید گوانین; BDCA; markers for distinct subsets of dendritic cells in human peripheral blood; CI; confidence interval; DENN; differentially expressed in normal and neoplastic cells domain; DENND1B; DENN domain containing 1B; ELISA; enzyme-linked immunosorbent assay; e
In situ detection of the activation of Rac1 and RalA small GTPases in mouse adipocytes by immunofluorescent microscopy following in vivo and ex vivo insulin stimulation
Keywords: فاکتور تبادل نوکلئوتید گوانین; DMEM; Dulbecco's modified Eagle's medium; GAP; GTPase-activating protein; GEF; guanine nucleotide exchange factor; GST; glutathione S-transferase; HA; hemagglutinin; m-rac1-KO; muscle-specific rac1 knockout; Myr-p110α; myristoylated p110α; PBS; phosphat
Original ArticleRas inhibitors display an anti-metastatic effect by downregulation of lysyl oxidase through inhibition of the Ras-PI3K-Akt-HIF-1α pathway
Keywords: فاکتور تبادل نوکلئوتید گوانین; Metastasis; Ras; Ras inhibitors; LOX; PI3K; HIF-1α; CRC; colorectal cancer; LOX; lysyl oxidase; PI3K; phosphatidylinositol 3-kinase; HIF; hypoxia-inducible factor; GEF; guanine nucleotide exchange factor; GAP; GTPase-activating protein; ECM; extracellula
Autophagosome Maturation and Fusion
Keywords: فاکتور تبادل نوکلئوتید گوانین; Atg; autophagy-related; PI 3-kinase complex; phosphatidyl-inositol 3-kinase complex; PAS; phagophore assembly site; PE; phosphatidylethanolamine; PI3P; phosphatidylinositol-3-phosphate; MTMR; myotubularin; GEF; guanine nucleotide exchange factor; ER; endo
Strategies for development of optogenetic systems and their applications
Keywords: فاکتور تبادل نوکلئوتید گوانین; AU1; Aureochrome 1; BLUF; blue-light-utilizing FAD; BphP1; bacterial bathy phytochrome 1; BV; biliverdin IXα; COP1; constitutively photomorphogenic 1; CRY2; cryptochrome 2; CIB1; cryptochrome interacting basic-helix-loop-helix protein 1; CPH1; cyanobacte
8-Oxoguanine DNA glycosylase1-driven DNA repair-A paradoxical role in lung aging
Keywords: فاکتور تبادل نوکلئوتید گوانین; 8-oxoG; 7,8-dihydro-8-oxoguanine; 8-oxodG; 7,8-dihydro-8-oxo-2â²-deoxyguanosine; BER; base excision repair; DNA dsbs; double strand breaks; DNA ssbs; single strand breaks; GEF; guanine nucleotide exchange factor; GOrilla; Gene Ontology enrichment analysi
Purinergic P2Y receptors: Molecular diversity and implications for treatment of cardiovascular diseases
Keywords: فاکتور تبادل نوکلئوتید گوانین; ADP; adenosine 5â²-diphosphate; AgRP; agouti-related peptide; AMPK; 5â²-AMP-activated protein kinase; ApnA; diadenosine polyphosphate; ApoE; apolipoprotein E; AT1R; angiotensin II type 1 receptor; ATP; adenosine 5â²-triphosphate; BN-PAGE; blue native-p
ACAP3, the GTPase-activating protein specific to the small GTPase Arf6, regulates neuronal migration in the developing cerebral cortex
Keywords: فاکتور تبادل نوکلئوتید گوانین; Small G protein; Arf6; Arf GAP; ACAP3; Neuronal migration; ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains; Arf; ADP-ribosylation factor; ARNO; Arf nucleotide binding site opener; BCIP; 5-bromo-4-chloro-3-indolyl phosphate; BRAG2; Brefeldin A
Stretch-induced actomyosin contraction in epithelial tubes: Mechanotransduction pathways for tubular homeostasis
Keywords: فاکتور تبادل نوکلئوتید گوانین; ATP; adenosine triphosphate; DAG; diacylglycerol; ECM; extracellular matrix; FAK; focal adhesion kinase; GAP; GTPase activating protein; GDI; guanine dissociation factor; GEF; guanine nucleotide exchange factor; GPCR; G protein coupled receptor; HUVEC; Hu
RhoA GTPase oxidation stimulates cell proliferation via nuclear factor-κB activation
Keywords: فاکتور تبادل نوکلئوتید گوانین; CA; constitutively active; DMEM; Dulbecco's modified Eagle's medium; DN; dominant negative; GAP; GTPase activating protein; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GDF; GDI displacement factor; GDI; guanine nucleotide dissociation inhibitor; GEF;
Regulation of HC11 mouse breast epithelial cell differentiation by the E-cadherin/Rac axis
Keywords: فاکتور تبادل نوکلئوتید گوانین; cRac1; Cellular Rac1; CRIB; Cdc42/Rac-interactive binding; E-cadherin; Epithelial cadherin; ECL; enhanced chemiluminescence; EGF; Epidermal growth factor; GAP; GTPase activating protein; GDP; guanosine 5â²-diphosphate; GEF; guanine nucleotide exchange fa
Role of ADP ribosylation factor6â Cytohesin1âPhospholipaseD signaling axis in U46619 induced activation of NADPH oxidase in pulmonary artery smooth muscle cell membrane
Keywords: فاکتور تبادل نوکلئوتید گوانین; Phospholipase D; NADPH oxidase; ADP rybosylation factor; Cytohesin; Thromboxane A2; Pulmonary artery smooth muscle cells; Tp; thromboxane A2 receptor; BFA; brefeldin A; PLD; Phospholipase D; Arf; ADP rybosylation fector; GEF; guanine nucleotide exchange f
The C1 domain of Vav3, a novel potential therapeutic target
Keywords: فاکتور تبادل نوکلئوتید گوانین; DAG; diacylglycerol; PKC; protein kinase C; GEF; guanine nucleotide exchange factor; PMA; phorbol 12-myristate 13-acetate; PDBu; phorbol 12,13-dibutyrate; CH domain; calponin homology domain; AD; acidic domain; DH; Dbl homology; PH; Pleckstrin homology; S
Identification of a novel protein interaction between Elmo1 and Cdc27
Keywords: فاکتور تبادل نوکلئوتید گوانین; Elmo; Cdc27; Dock1; Interaction; Efferocytosis; TAMRA; 5-(and-6)-Carboxytetramethylrhodamine; GEF; guanine nucleotide exchange factor; APC; anaphase promoting complex; GST; glutathione S-transferase; TPR; tetratricopeptide repeat; TLC; total cell lysates;
Fluorescence bioimaging of intracellular signaling and its clinical application
Keywords: فاکتور تبادل نوکلئوتید گوانین; BAPTA-AM; acetoxymethyl ester of 1,2-bis(2-aminophenoxy)ethane-N,N,Nâ²,Nâ²-tetraacetic acid; BiFC; bimolecular fluorescence complementation; CML; chronic myeloid leukemia; CFP; cyan-emitting mutant of green fluorescent protein; FRET; Förster resonance
ReviewSearching for the Chokehold of NRAS Mutant Melanoma
Keywords: فاکتور تبادل نوکلئوتید گوانین; ERK; extracellular signal-regulated kinase; GEF; guanine nucleotide exchange factor; HRAS; Harvey-rat-sarcoma homolog; KRAS; Kirsten-rat-sarcoma homolog; MAPK; mitogen-activated protein kinase; NRAS; neuroblastoma rat-sarcoma homolog; RAL; retinaldehyde;
Dock10 regulates CD23 expression and sustains B-cell lymphopoiesis in secondary lymphoid tissue
Keywords: فاکتور تبادل نوکلئوتید گوانین; ANOVA; analysis of variance; BCR; B-cell receptor; BM; bone marrow; CM; complete medium; DN; double negative; DP; double positive; FO; follicular; GC; germinal center; GEF; guanine nucleotide exchange factor; GEP; gene expression profile; IB; isolation bu
Immunoreceptors on neutrophils
Keywords: فاکتور تبادل نوکلئوتید گوانین; ADCC; antibody-dependent cellular cytotoxicity; ANCAs; anti-neutrophil autoantibodies; Btk; Bruton's tyrosine kinase; DAG; diacyl-glycerol; DAP12; DNAX activation protein of 12Â kDa; ERK; extracellular signal-regulated kinase; fMLP; N-Formylmethionine-leu
Differences in the Phosphorylation-Dependent Regulation of Prenylation of Rap1A and Rap1B
Keywords: فاکتور تبادل نوکلئوتید گوانین; PBR; polybasic region; GEF; guanine nucleotide exchange factor; PKA; protein kinase A; Ctx; cholera toxin; GPCR; Gαs protein-coupled receptor; NECA; 5â²-N-ethylcarboxamidoadenosine; Iso; isoproterenol; GFP; green fluorescent protein; protein isoprenylat
Type II PKAs are anchored to mature insulin secretory granules in INS-1 β-cells and required for cAMP-dependent potentiation of exocytosis
Keywords: فاکتور تبادل نوکلئوتید گوانین; Pancreatic; Endocrine; Insulin; Exocytosis; Potentiation; Protein kinase-A; cAMP; Compartmentalization; AKAP; A-Kinase anchoring protein; Epac; Exchange proteins directly activated by cAMP; GEF; Guanine nucleotide exchange factor; GLP-1; Glucagon-like pep
The signaling module cAMP/Epac/Rap1/PLCε/IP3 mobilizes acrosomal calcium during sperm exocytosis
Keywords: فاکتور تبادل نوکلئوتید گوانین; 2-APB; 2-aminoethoxydiphenylborate; AR; acrosome reaction; 6-Bnz-cAMP; N6-benzoyladenosine-3â²,5â²-cyclic monophosphate; cAMP; cyclic adenosine monophosphate; Epac; guanine nucleotide exchange factor activated by cAMP; GEF; guanine nucleotide exchange f
On the use of Legionella/Rickettsia chimeras to investigate the structure and regulation of Rickettsia effector RalF
Keywords: فاکتور تبادل نوکلئوتید گوانین; Small GTPases; Guanine nucleotide exchange factor; Bacterial pathogens; Chimera;