دانلود مقالات ISI درباره نیمه حداکثر غلظت مهاری + ترجمه فارسی

Can the inhibition of cytochrome P450 in aquatic invertebrates due to azole fungicides be estimated with in silico and in vitro models and extrapolated between species?

Keywords: نیمه حداکثر غلظت مهاری; ACN; acetonitrile; BSA; bovine serum albumin; DTT; DL-dithiothreitol; ECOD; 7-ethoxycoumarin-O-dealkylase; EDTA; ethylenediaminetetraacetic acid disodium salt dihydrate; IC50; half maximal inhibitory concentration; K2HPO43H2O; potassium phosphate dibasic

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Extract from Butea monosperma inhibits β-catenin/Tcf signaling in SW480 human colon cancer cells

Keywords: نیمه حداکثر غلظت مهاری; CRC; colorectal cancer; NBF-BMFE; n-butanol fraction of B. monosperma flower extract; APC; adenomatous polyposis coli; GSK-3β; glycogen synthase kinase 3β; CK1; casein kinase 1; LRP5/6; low density lipoprotein receptor- related protein; Dvl; dishevelled

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Identification of novel Amurin-2 variants from the skin secretion of Rana amurensis, and the design of cationicity-enhanced analogues

Keywords: نیمه حداکثر غلظت مهاری; Antimicrobial peptide; Amphibian skin secretion; Cationicity-related peptide design; AMP; antimicrobial peptide; MRSA; methicillin-resistant Staphylococcus aureus; HDPs; host-defence peptides; CD; circular dichroism; MHB; Mueller-Hinton Broth; MIC; minimu

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

The genome-wide sequence specificity of DNA cleavage by bleomycin analogues in human cells

Keywords: نیمه حداکثر غلظت مهاری; BLM; bleomycin; IC50; half maximal inhibitory concentration; TSS; transcription start site; ZBM; zorbamycin; D; G A or T nucleotides; M; A or C nucleotides; R; G or A nucleotides; Y; C or T nucleotides; Anti-tumour agent; Bleomycin analogue; DNA sequence

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Coupling of partial nitritation and anammox in two- and one-stage systems: Process operation, N2O emission and microbial community

Keywords: نیمه حداکثر غلظت مهاری; Partial nitritation; Anaerobic ammonium oxidation; Sequencing batch reactor; Sewage sludge anaerobic digester supernatant; Nitrous oxide emission; Phosphate; ALK; alkalinity; anammox; anaerobic ammonium oxidation; ANR; autotrophic N removal; AOB; ammonium

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

Discovery of novel piperonyl derivatives as diapophytoene desaturase inhibitors for the treatment of methicillin-, vancomycin- and linezolid-resistant Staphylococcus aureus infections

Keywords: نیمه حداکثر غلظت مهاری; CrtN inhibitor; STX biosynthesis; Pigment inhibitory activity; Resistant S. aureus; S. aureus; Staphylococcus aureus; MRSA; methicillin-resistant Staphylococcus aureus; STX; staphyloxanthin; NTF; naftifine hydrochloride; CrtM; dehydrosqualene synthase;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2018 سفارش ترجمه

RNA Aptamer Delivery through Intact Human Skin

Keywords: نیمه حداکثر غلظت مهاری; DHA; dual hybridization assay; IC50; half maximal inhibitory concentration; MW; molecular weight; SC; stratum corneum; Th; T helper;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

Zinc chloride-induced TRPA1 activation does not contribute to toxicity in vitro

Keywords: نیمه حداکثر غلظت مهاری; °C; degree celcius; AU; arbitrary units; AITC; allylisothiocyanate; BSA; bovine serum albumin; Ca2+; calcium ion; [Ca2+]i; intracellular calcium levels; CaCl2; calcium chloride; cDNA; complementary DNA; Cys; cystidine; DMEM; Dulbecco's Modified Eagleâ€

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

Influence of silibinin and β-β-dimethylacrylshikonin on chordoma cells

Keywords: نیمه حداکثر غلظت مهاری; Chordoma; β-β-dimethylacrylshikonin; Silibinin; Apoptosis; ACTB; actin beta; AKT; AKT serine/threonine kinase; BAD; BCL2 associated agonist of cell death; BAK; BCL2 antagonist/killer; BAX; BCL2 associated X protein; BCL-2; B cell leukemia/lymphoma 2; BH

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

Dependence of HSP27 cellular level on protein kinase CK2 discloses novel therapeutic strategies

Keywords: نیمه حداکثر غلظت مهاری; Protein kinase CK2; HSP27, SMURF2; Thermotherapy; Cancer; HSP; Heat shock protein; SMURF2; Smad ubiquitination regulatory factor 2; siRNA; small interfering RNA; PDCD5; Programmed cell death protein 5; CX-4945; (5-[(3-Chlorophenyl)amino]-benzo[c]-2,6-naph

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

Anti-tumor effect of AZD8055 against neuroblastoma cells in vitro and in vivo

Keywords: نیمه حداکثر غلظت مهاری; NB; Neuroblastoma; IGF; Insulin and insulin-like growth factors; PI3K; phosphatidylinositol 3-kinase; mTOR; mammalian target of rapamycin; mTORC1; mTOR complex 1; mTORC2; mTOR complex 2; p70S6K; p70 ribosomal protein S6 kinase; 4E-BP1; eukaryotic translat

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2018 سفارش ترجمه

The novel brassinosteroid analog BR4848 inhibits angiogenesis in human endothelial cells and induces apoptosis in human cancer cells in vitro

Keywords: نیمه حداکثر غلظت مهاری; Ac-DEVD-AMC; N-acetyl-Asp-Glu-Val-Asp-7-amido-4-methylcoumarin; Ac-DEVD-CHO; N-acetyl-Asp-Glu-Val-Asp-al; Ang2; Angiopoietin-2; AR; androgen receptor; BR; brassinosteroid; CHAPS; 3[(3-cholamidopropyl)dimethylammonio]-propanesulphonic acid; DMEM; Dulbeccoâ

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

Tatanan A from the Acorus calamus L. root inhibited dengue virus proliferation and infections

Keywords: نیمه حداکثر غلظت مهاری; Acorus calamus l; Tatanan A; Dengue; DENV2 infection; CC; column chromatography; CC50; half maximal cytotoxicity concentration; CPE; cytopathic effect; DENV; dengue virus; DENV2; dengue virus type 2; DEPT; distortionless enhancement by polarization transf

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

In vitro 4-Aryloxy-7-chloroquinoline derivatives are effective in mono- and combined therapy against Leishmania donovani and induce mitocondrial membrane potential disruption

Keywords: نیمه حداکثر غلظت مهاری; AMB; amphotericin B; DMSO; dimethyl sulfoxide; FIC; interaction index; IC50; half maximal inhibitory concentration; MIC; minimum inhibitory concentration that produce total death of the culture parasite; MTF; miltefosine; MTT; 3-(4,5-dimethylthiazol-2-yl)

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

Development of potent and proteolytically stable human neuromedin U receptor agonists

Keywords: نیمه حداکثر غلظت مهاری; Neuromedin U (NMU); NMU-8; Neuromedin U receptor agonists; Plasma stability; 1′Nal; 1′-naphtylalanine; 2′Nal; 2′-naphtylalanine; 7-OH-Tic; 7-hydroxy-L-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; ACN; acetonitrile; AUC; area under the curve;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

An appraisal on synthetic and pharmaceutical perspectives of pyrazolo[4,3-d]pyrimidine scaffold

Keywords: نیمه حداکثر غلظت مهاری; A. flavus; Aspergillus flavus; C. albicans; Candida albicans; cAMP; cyclic adenosine monophosphate; CDK; cyclin-dependent kinase; CNS; central nervous system; COX; cyclooxygenase; CRF; corticotropin-releasing hormone; CRK; cdc2-related kinase; CYC6; cycli

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design

Keywords: نیمه حداکثر غلظت مهاری; Crystal structure; Inhibition properties; Benzoic acid derivatives; Serine-β-lactamase inhibitors; Fragments; Structure-guided drug design; DMSO; dimethyl sulfoxide; OXA; oxacillinase; IC50; half maximal inhibitory concentration; LE; ligand efficiency; M

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Screening for inhibitory activity of essential oils on fungal tomato pathogen Stemphylium solani Weber

Keywords: نیمه حداکثر غلظت مهاری; AC; Aloysia citrodora; AL; Aloysia lycioides; BP; Baccharis psiadioides; BT; Baccharis trimera; BA; Baccharis articulata; BO; Baccharis ochraceae; CC; Cinnamomum camphora var. linaloolifera; EG; Eucalyptus globulus; ES; Eucalyptus staigeriana; FV; Foenicu

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Size-dependent pharmacological activities of differently degraded fucoidan fractions from Fucus vesiculosus

Keywords: نیمه حداکثر غلظت مهاری; APTT; activated partial thromboplastin time; C1-INH; C1 esterase inhibitor; DC; doubling concentration; dn/dc; refractive index increment; DS; degree of sulfation; F.v.-fuc; fucoidan extracted from Fucus vesiculosus; FXII; factor XII; IC50; half maximal i

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

MicroRNA-139-5p affects cisplatin sensitivity in human nasopharyngeal carcinoma cells by regulating the epithelial-to-mesenchymal transition

Keywords: نیمه حداکثر غلظت مهاری; Akt; protein kinase B; Bax; Bcl-2 associated X; Bcl-2; B-cell lymphoma 2; DAPI; 4′,6-diamidino-2-phenylindole; DDP; cisplatin; EMT; epithelial-to-mesenchymal transition; FBS; fetal bovine serum; GAPDH; glyceraldeyde 3-phosphate dehydrogenase; HRP; horse

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

Inhibitory effects of (+)-spectaline and iso-6-spectaline from Senna spectabilis on the growth and ultrastructure of human-infective species Trypanosoma brucei rhodesiense bloodstream form

Keywords: نیمه حداکثر غلظت مهاری; Senna spectabilis; Piperidine alkaloids; (+)-spectaline; Iso-6-spectaline; Tyrpanosoma brucei rhodesiense; Autophagy; HAT; human African trypanosomiasis; DNDi; Drugs for Neglected Diseases initiative; IC50; half maximal inhibitory concentration; PCD; prog

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2018 سفارش ترجمه

Redox-stimuli-responsive drug delivery systems with supramolecular ferrocenyl-containing polymers for controlled release

Keywords: نیمه حداکثر غلظت مهاری; A549; A549 lung cancer cells; AAO; anodized alumina substrates; Ad; adamantane; ALMA; allyl methacrylate; ATRP; atom transfer radical polymerization; AuNPs; gold nanoparticles; CAC; critical aggregation concentration; CB[7]; cucurbituril; β-CD; β-cyclod

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Synthesis and biological evaluation of a library of hybrid derivatives as inhibitors of influenza virus PA-PB1 interaction

Keywords: نیمه حداکثر غلظت مهاری; Anti-Influenza; PA-PB1; RdRp; Amino acid coupling; SPPS; Diphenyl-pyridine; AcOEt; Ethyl acetate; CC50; Half maximal cytotoxic concentration; cRNA; complementar RNA; DCM; dichloromethane; DDQ; 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone; DIPEA; N,N-Diisopro

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

Bioconversion of alkaloids to high-value chemicals: Comparative analysis of newly isolated lupanine degrading strains

Keywords: نیمه حداکثر غلظت مهاری; Lupanine; Quinolizidine alkaloids; Biodegradation; Bioconversion; Toxicity assessment; M9; Minimal microbial growth medium; GC; Gas chromatography; EC50; Half maximal effective concentration; ITS; Internal transcribed spacer sequence; NCBI; National Cente

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

Specific enzyme functionalities of Fusarium oxysporum compared to host plants

Keywords: نیمه حداکثر غلظت مهاری; Ap4A; diadenosine tetraphosphate; CAT; carnitine acetyltransferase; CDP-choline; cytidine diphosphate choline; CWDEs; cell walls degrading enzymes; DcpS; decapping scavenger enzyme; EC; enzyme commission numbers; HCCS; holocytochrome-c synthase; HGT; hori

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2018 سفارش ترجمه

Fermented non-digestible fraction from combined nixtamalized corn (Zea mays L.)/cooked common bean (Phaseolus vulgaris L.) chips modulate anti-inflammatory markers on RAW 264.7 macrophages

Keywords: نیمه حداکثر غلظت مهاری; AA; acetic acid; ATCC; American Type Cell Culture; BA; butyric acid; DCF; digested chip fraction; DMSO; dimethyl sulfoxide; DMEM; Dulbecco's modified eagle medium; FNDCF; fermented non-digested chip fraction; GC-MS; gas chromatography-mass spectrometr

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

Vitis amurensis Rupr: A review of chemistry and pharmacology

Keywords: نیمه حداکثر غلظت مهاری; Vitis amurensis Rupr; Chemistry; Pharmacology; CYA; cyanidin; DEL; delphinidin; PET; petunidin; PEO; peonidin; MAL; malvidin; IC50; half maximal inhibitory concentration; LPS; lipopolysaccharide; MIC; Minimum Inhibitory Concentration; MBC; Minimum Bacteri

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Characterization of an N-terminal mutant of αA-crystallin αA-R21Q associated with congenital cataract

Keywords: نیمه حداکثر غلظت مهاری; αA-WT; wild-type αA-crystallin; αA-R21Q; αA-crystallin mutant R21Q; sHSP; small heat shock protein; ACD; alpha crystallin domain; SEC; Size Exclusion Chromatography; Bis-ANS; 4,4′-Dianilino-1,1′-Binaphthyl-5,5′-Disulfonic Acid; ADH; alcohol

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Acylguanidine derivatives of zanamivir and oseltamivir: Potential orally available prodrugs against influenza viruses

Keywords: نیمه حداکثر غلظت مهاری; Acylguanidine; Zanamivir; Oseltamivir; Neuraminidase inhibitor; Influenza; Arg; arginine; Boc; tert-butoxycarbonyl; (Boc)2O; di(tert-butyl) dicarbonate; CC50; half maximal cytotoxicity concentration; CPE; cytopathic effect; DIEA; diisopropyl ethylamine; D

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2018 سفارش ترجمه

Bioinformatics analysis of ROP8 protein to improve vaccine design against Toxoplasma gondii

Keywords: نیمه حداکثر غلظت مهاری; Toxoplasma gondii; ROP8; Bioinformatics analysis; Vaccine; 3D; three-dimensional; ACC; auto cross covariance; ANN; artificial neural network; CD; cluster of differentiation; CI; confidence interval; CTL; cytotoxic T lymphocyte; GOR; Garnier-Osguthorpe-Rob

دانلود رایگان متن کامل مقاله ISI 49 صفحه سال انتشار : 2018 سفارش ترجمه

Design, synthesis and biological screening of 2-aminobenzamides as selective HDAC3 inhibitors with promising anticancer effects

Keywords: نیمه حداکثر غلظت مهاری; B16F10; murine melanoma cells; CDCl3; deuterated chloroform; CTCL; cutaneous T-cell lymphoma; DCM; dichloromethane; DFT; density functional theory; DMAP; 4-Dimethylaminopyridine; DMEM; Dulbecco's modified Eagle's media; DMF; dimethylformamide; DMSO; dimet

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2018 سفارش ترجمه

The traditional uses, phytochemistry, and pharmacology of Atractylodes macrocephala Koidz.: A review

Keywords: نیمه حداکثر غلظت مهاری; AM; Atractylodes macrocephala Koidz.; TCM; traditional Chinese medicine; UPLC; ultra-performance liquid chromatography; PDA; photo-diode array; IR; infrared spectroscopy; HS-LP-LPE; headspace liquid phase-liquid-phase extraction; GC-MS; gas chromatography

دانلود رایگان متن کامل مقاله ISI 57 صفحه سال انتشار : 2018 سفارش ترجمه

Novel combined Ato-C treatment synergistically suppresses proliferation of Bcr-Abl-positive leukemic cells in vitro and in vivo

Keywords: نیمه حداکثر غلظت مهاری; Arsenic trioxide; Cisplatin; Combination therapy; Bcr-Abl-positive leukemia; Apoptosis; APL; acute promyelocytic leukemia; ATO; arsenic trioxide; Ato-C; ATO/CDDP; CDDP; Cisplatin; CI; combination index; DRI; dose-reduction index; CML; Chronic myelogenous

دانلود رایگان متن کامل مقاله ISI 58 صفحه سال انتشار : 2018 سفارش ترجمه

Ethnomedical uses and pharmacological activities of most prevalent species of genus Piper in Panama: A review

Keywords: نیمه حداکثر غلظت مهاری; ED50; effective dose concentration; GI100; 100% growth inhibition; IC50; half maximal inhibitory concentration; LC50; 50% lethal concentration; MIC; minimum inhibitory concentration; MAR; maximum amount required; Piper spp.; Ethnomedicine; Genus Piper; Pa

دانلود رایگان متن کامل مقاله ISI 79 صفحه سال انتشار : 2018 سفارش ترجمه

Discovery of the selective sphingomyelin synthase 2 inhibitors with the novel structure of oxazolopyridine

Keywords: نیمه حداکثر غلظت مهاری; SMS; sphingomyelin synthase; SM; sphingomyelin; PC; phosphatidylcholine; CHD; coronary heart disease; SMase; sphingomyelinase; SPT; serine palmitoyl transferase; AS; atherosclerosis; SMSr; SMS related protein; SAR; structure-activity relationships; IC50;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Comparison of the acute inhibitory effects of Tetrodotoxin (TTX) in rat and human neuronal networks for risk assessment purposes

Keywords: نیمه حداکثر غلظت مهاری; ARfD; acute reference dose; DIV; days in vitro; EFSA; European Food Safety Authority; FBS; fetal bovine serum; hIPSC; human-induced pluripotent stem cell; IC50; half maximal inhibitory concentration; LD50; median lethal dose; LOEAL; lowest observed advers

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Identification of repaglinide as a therapeutic drug for glioblastoma multiforme

Keywords: نیمه حداکثر غلظت مهاری; Repaglinide; Glioma; Bioinformatics; Drug repositioning; Cancer therapy; Brain tumor; CMap; connectivity map; DE genes; differentially expressed genes; DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulfoxide; FBS; fetal bovine serum; GBM; gliob

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Extracts and compounds active on TRP ion channels from Waldheimia glabra, a ritual medicinal plant from Himalaya

Keywords: نیمه حداکثر غلظت مهاری; Waldheimia glabra (Decne.) Regel; TRP channels; GC/MS; NMR; Ludartin; TRP; Transient receptor potential; AITC; allyl isothiocyanate; EC50; half maximal effective concentration; IC50; half maximal inhibitory concentration;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Alibertia edulis (L.C. Rich.) A.C. Rich - A potent diuretic arising from Brazilian indigenous species

Keywords: نیمه حداکثر غلظت مهاری; 2K1C; Two-kidney-one-clip; AEAE; Alibertia edulis aqueous extract; AF; Acetate fraction; ALT; Alanine transaminase; ANOVA; Analysis of variance; AqF; Aqueous fraction; AST; Aspartate transaminase; BF; n-buthanol fraction; BW; Body weight; Ca+2; Calcium; C

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

In vitro biological assessment of Homalium zeylanicum and isolation of lucidenic acid A triterpenoid

Keywords: نیمه حداکثر غلظت مهاری; HAHZ; hydro alcoholic extract of Homalium zeylanicum; TLC; thin layer chromatography; Rf; Retardation factor; TPC; total phenolic contents; TFC; total flavonoid contents; DPPH; 2,2-diphenyl-1-picrylhydrazyl; NO; Nitric oxide; OH; hydroxyl; SOD; superoxide

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Reassessing APOBEC3G Inhibition by HIV-1 Vif-Derived Peptides

Keywords: نیمه حداکثر غلظت مهاری; A3G; APOBEC3G; AID; activation-induced deaminase; CBF-β; core-binding factor beta; EMSA; electrophoretic mobility shift assays; G-to-A; guanine-to-adenine; HPLC; high-performance liquid chromatography; IC50; half maximal inhibitory concentration; MS; mas

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

A new exploration of Dregea volubilis flowers: Focusing on antioxidant and antidiabetic properties

Keywords: نیمه حداکثر غلظت مهاری; DVHA; hydroalcoholic flower extract of D. volubilis; GAE; gallic acid equivalent; QE; quercetin equivalent; DPPH; 1,1-diphenyl-2-picryl-hydrazyl; IC50; half maximal inhibitory concentration; FT-IR; Fourier transform infrared; UHPLC; ultra high performance

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Synthetic polyphenol compounds inhibit β-catenin/Tcf signaling: Structure-activity relationship

Keywords: نیمه حداکثر غلظت مهاری; APC; Axin-adenomatous polyposis coli; BCA; bicinchoninic acid; CBP; CREB binding protein; CRC; colorectal cancer; DMSO; dimethyl sulfoxide; Dsh; disheveled; EMSA; electrophoretic mobility shift assay; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; GSK;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

OP16, a novel ent-kaurene diterpenoid, potentiates the antitumor effect of rapamycin by inhibiting rapamycin-induced feedback activation of Akt signaling in esophageal squamous cell carcinoma

Keywords: نیمه حداکثر غلظت مهاری; Akt; protein kinase B; DMSO; dimethyl sulfoxide; ESCC; esophageal squamous cell carcinoma; FBS; fetal bovine serum; IC50; half maximal inhibitory concentration; mTOR; mammalian target of rapamycin; PI3K; phosphatidylinositol 3 kinase; Rapa; rapamycin; Rap

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

(−)-UB006: A new fatty acid synthase inhibitor and cytotoxic agent without anorexic side effects

Keywords: نیمه حداکثر غلظت مهاری; FAS fatty acid synthase; C75 derivatives; CPT1 carnitine palmitoyltransferase 1; Ovarian cell cancer; 18S; 18S ribosomal RNA; BIP; binding immunoglobulin protein; BSA; bovine serum albumin; CASP3; caspase-3; CPT1; carnitine palmitoyltransferase 1; DDIT4/R

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Mycobacterium tuberculosis chorismate mutase: A potential target for TB

Keywords: نیمه حداکثر غلظت مهاری; Tuberculosis; Mycobacterium tuberculosis; Chorismate mutase; Inhibitors; BsCM; Bacillus subtilis chorismate mutase; CM; chorismate mutase; DAHP; 3-deoxy-d-arabinoheptulosonate 7-phosphate; EcCM; Escherichia coli chorismate mutase; HIV/AIDS; human Immunode

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Pyrrolizines: Design, synthesis, anticancer evaluation and investigation of the potential mechanism of action

Keywords: نیمه حداکثر غلظت مهاری; ALK1; activin receptor-like kinase; CDCl3; deuterated chloroform; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide; DSV; discovery studio visualizer; DYRK3; dual specificity tyrosine phosphorylation-regulated kinase; CDK2; cyclin-depende

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

Prediction of Hepatic Efflux Transporter-Mediated Drug Interactions: When Is it Optimal to Measure Intracellular Unbound Fraction of Inhibitors?

Keywords: نیمه حداکثر غلظت مهاری; transporters; drug interaction; hepatocytes; pharmacokinetics/pharmacodynamics; protein binding; AFE; average fold error; AUC; area under the curve; BSA; bovine serum albumin; CLBile; biliary clearance; CLBL; basolateral efflux clearance; CLUptake; uptake

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2017 سفارش ترجمه

Na+/K+-ATPase interaction with methylglyoxal as reactive metabolic side product

Keywords: نیمه حداکثر غلظت مهاری; aa residue; amino acid residue; AMG; aminoguanidine, also pimagedine; Arg (R); arginine; ATP; adenosine triphosphate; BSA; bovine serum albumin; CHER; catalytic hydrogen evolution reaction; CML; Nε-(carboxymethyl)lysine; CPS; constant-current chronopoten

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2017 سفارش ترجمه

Evaluation of invitro α-amylase and α-glucosidase inhibitory potential of N2O2 schiff base Zn complex

Keywords: نیمه حداکثر غلظت مهاری; ABTS; 2,2′-azinobis-3-ethylbenzothiazoline-6-sulfonic acid; DNS; dinitro salicylic acid; DPPH; 1-1-diphenyl 2-picryl hydrazyl; IC50; half maximal inhibitory concentration; LB; Lineweaver-Burk; MIC; minimum inhibitory concentration; S. aureus; Staphylo

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2017 سفارش ترجمه