دانلود مقالات ISI درباره Hek + ترجمه فارسی

HBP1 phosphorylation by AKT regulates its transcriptional activity and glioblastoma cell proliferation

Keywords: DNMT1; DNA-methyltransferase 1; FOXO; Forkhead box O transcription factors; GST; glutathione S-transferase; HBP1; HMG-box protein 1; HEK; human embryonic kidney; HMG; high mobility group; HPLC; high performance liquid chromatography; KD; kinase dead; MS;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Dehydroevodiamine and hortiamine, alkaloids from the traditional Chinese herbal drug Evodia rutaecarpa, are IKr blockers with proarrhythmic effects in vitro and in vivo

Keywords: DHE; dehydroevodiamine; IKr; rapid delayed rectifier current; APD; action potential duration; EAD; early afterdepolarization; cAVB; chronic atrioventricular block; TdP; Torsade de Pointes arrhythmia; hiPSC-CM; human induced pluripotent stem cell-derived c

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

Pathogenic IgG4 autoantibodies from endemic pemphigus foliaceus recognize a desmoglein-1 conformational epitope

Keywords: Cell adhesion molecule; Desmosome; IgG4 autoantibody; Skin autoimmunity; FS; fogo selvage; Dsg; desmoglein; Dsc; desmocollin; EC; extracellular; PF; pemphigus foliaceus; HEK; human embryonic kidney;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

Small molecule PGC-1α1 protein stabilizers induce adipocyte Ucp1 expression and uncoupled mitochondrial respiration

Keywords: Small molecule screening; PGC-1a; PGC-1alpha; PGC-1alpha1; Protein stabilization; UCP1; Mitochondrial respiration; Brown adipose tissue; C/EBP; CCAAT-enhancer-binding proteins; FCCP; carbonyl cyanide-4-(trifluoromethoxy)phenylhydrazone; HEK; human embryon

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2018 سفارش ترجمه

Integrating plant and animal biology for the search of novel DNA damage biomarkers

Keywords: ARP; actin related protein; ASK; Arabidopsis SPK1-like; At; Arabidopsis thaliana; ATAF; arabidopsis transcription activation factor; ATM; ataxia telangiectasia mutated; ATR; ATM and Rad3-related; ATRIP; ATR-interacting protein; BARD; BRCA1-associated RING

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2018 سفارش ترجمه

Membrane cholesterol modulates STEAP2 conformation during dynamic intracellular trafficking processes leading to broad subcellular distribution

Keywords: BSA; bovine serum albumin; DIC; differential interference contrast; ER; endoplasmic reticulum; FAD; flavin adenine dinucleotide; GFP; green fluorescent protein; HEK; human embryonic kidney; mAb; monoclonal antibody; MOPS; 3-(N-morpholino)propanesulfonic a

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2018 سفارش ترجمه

Deficiency in GnRH receptor trafficking due to a novel homozygous mutation causes idiopathic hypogonadotropic hypogonadism in three prepubertal siblings

Keywords: CDGP; constitutional delay of growth and puberty; CHO; Chinese hamster ovary; E2; estradiol; ER; endoplasmic reticulum; FSH; follicle-stimulating hormone; GnRH; gonadotropin-releasing hormone; HEK; human embryonic kidney; H-P-G axis; hypothalamic-pituit

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2018 سفارش ترجمه

TRPM7 functions in non-neuronal and neuronal systems: Perspectives on its role in the adult brain

Keywords: TRPM7; transient receptor potential melastatin like 7; PI3K; phosphatidyl inositol 3-kinase; Akt; serine-threonine kinase; S6K1; S6 kinase 1; mTORC; mammalian target of rapamycin complex; HEK; human embryonic kidney; TRPM6; transient receptor potential me

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

A systematic analysis of the expression of the anti-HIV VRC01 antibody in Pichia pastoris through signal peptide optimization

Keywords: Pichia pastoris / Komagataella phaffi; Broadly neutralizing antibody; VRC01; Signal peptide; 2A sequence; AA; α-amylase; α-MF; α-mating factor; αK; α-mating factor K; αKS; α-mating factor KS; αT; α-mating factor T; AOX1; alcohol oxidase 1; AP; al

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

Development of potent and proteolytically stable human neuromedin U receptor agonists

Keywords: Neuromedin U (NMU); NMU-8; Neuromedin U receptor agonists; Plasma stability; 1′Nal; 1′-naphtylalanine; 2′Nal; 2′-naphtylalanine; 7-OH-Tic; 7-hydroxy-L-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; ACN; acetonitrile; AUC; area under the curve;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

SOX9 Transcriptionally Regulates mTOR-Induced Proliferation of Basal Cell Carcinomas

Keywords: 4E-BP; 4E binding protein; AKT; v-akt murine thymoma viral oncogene homolog; BCC; basal cell carcinoma; BCNS; basal cell nevus syndrome; CCND1; cyclin D1; GLI; glioma-associated oncogene homolog; HEK; human embryonic kidney; ITRA; itraconazole; mTOR; mamm

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

MicroRNAs-103/107 Regulate Autophagy in the Epidermis

Keywords: HEK; human epidermal keratinocyte; HLEK; human limbal epithelial keratinocyte; miR; microRNA; PKC; protein kinase C;

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2018 سفارش ترجمه

Chemical characterization and cytotoxic, genotoxic, and mutagenic properties of Baccharis trinervis (Lam, Persoon) from Colombia and Brazil

Keywords: CHO; Chinese Hamster Ovary; AE; Aqueous extracts; B; Brazil; C; Colombia; EAF; Ethyl Acetate Fraction; BF; Butanol Extract; ARF; Aqueous Residue Fraction; HPLC; High Performance Liquid Chromatography; HRMS; High Resolution Mass Spectrometry; MTT; 3-(4.5-d

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2018 سفارش ترجمه

Synthesis and biological evaluation of a library of hybrid derivatives as inhibitors of influenza virus PA-PB1 interaction

Keywords: Anti-Influenza; PA-PB1; RdRp; Amino acid coupling; SPPS; Diphenyl-pyridine; AcOEt; Ethyl acetate; CC50; Half maximal cytotoxic concentration; cRNA; complementar RNA; DCM; dichloromethane; DDQ; 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone; DIPEA; N,N-Diisopro

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

The mouse Gm853 gene encodes a novel enzyme: Leucine decarboxylase

Keywords: AZ; antizyme; AZIN; antizyme inhibitor; DFMO; α-difluoromethylornithine; DMEM; Dulbecco's Modified Eagle Medium; HEK; human embryonic kidney; LDC; leucine decarboxylase; ODC; ornithine decarboxylase; PLP; pyridoxal phosphate; Polyamine; Isopentylamine; A

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

Androgen receptor (AR) degradation enhancer ASC-J9® in an FDA-approved formulated solution suppresses castration resistant prostate cancer cell growth

Keywords: Androgen receptor; Prostate cancer; Prostate therapy; ASC-J9®; IC50; Epithelial cells; Stromal cells; Fibroblasts; Myofibroblasts; Apoptosis; FDA-approved formula; AR; androgen receptor; PCa; prostate cancer; RT-PCR; reverse transcription polymerase chai

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Notch signaling is impaired during inflammation in a Lunatic Fringe-dependent manner

Keywords: AJ; adherence junction; APC; Allophycocyanin; BBB; blood-brain barrier; BECs; brain endothelial cells; CNS; central nervous system; DAPT; N-[N-(3,5-Difluorophenacetyl)-l-alanyl]-S-phenylglycine t-butyl ester; DLL1, -3 and -4; Delta-like family ligand 1, -

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

Sumoylation and ubiquitylation crosstalk in the control of ΔNp63α protein stability

Keywords: SUMO; Small Ubiquitin-like Modifier; Ub; ubiquitin; SHFM-IV; Split Hand Foot Malformation; Ubc9; ubiquitin carrier protein 9; p14ARF; p14 Alternative Reading Frame; GAM-1; Gallus Anti Mortem 1; GADD45; The Growth Arrest and DNA Damage; DLX5; Distal-Less H

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Solution NMR views of dynamical ordering of biomacromolecules

Keywords: ALS; Amyotrophic Lateral Sclerosis; CPMG; Carr-Purcell-Meiboom-Gill; CPP; Cell Penetrating Peptide; CHO; Chinese Hamster Ovary Cells; Rex; Chemical/Conformational Exchange; (C)EST; (Chemical) Exchange Saturation Transfer; CSA; Chemical Shift Anisotropy; C

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2018 سفارش ترجمه

Comprehensive identification of proteins binding to RNA G-quadruplex motifs in the 5′ UTR of tumor-associated mRNAs

Keywords: RNA G-quadruplexes; Post-transcriptional regulation; RNA-binding proteins; Translational regulation; Cancer; CD; Circular dichroism; FDR; False discovery rate; FF Luc; firefly luciferase; FTMS; Fourier transform mass spectrometry; GO; Gene Ontology; GQ; G

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2018 سفارش ترجمه

Ligand-dependent modulation of hOCT1 transport reveals discrete ligand binding sites within the substrate translocation channel

Keywords: OCT1; Organic Cation Transporter 1; hOCT1; human OCT1; HEK; Human Embryonic Kidney; EV; empty vector; MPP+; 1-methyl-4-phenylpyridinium; TEA; tetraethylammonium; CCF; competitive counter flow; TMD; transmembrane domains; CHARMm; Chemistry at Harvard Macro

دانلود رایگان متن کامل مقاله ISI 49 صفحه سال انتشار : 2018 سفارش ترجمه

Neuroanatomical distribution and function of the vasopressin V1B receptor in the rat brain deciphered using specific fluorescent ligands

Keywords: ACTH; adrenocorticotropic hormone; AVP; arginine8 vasopressin; AC; adenylyl cyclase; BSA; bovine serum albumin; CaMKII; calmoduline-dependent serine/threonine kinase II; CHO; chinese hamster ovary; DG; dentate gyrus; DMEM; Dulbecco's modified Eagles'

دانلود رایگان متن کامل مقاله ISI 51 صفحه سال انتشار : 2018 سفارش ترجمه

On the G protein-coupling selectivity of the native A2B adenosine receptor

Keywords: BAY60-6583; 2-[[6-amino-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]-2-pyridinyl]thio]-acetamide; cAMP; 3′,5′-cyclic adenosine monophosphate; CE3F4; 5,7-dibromo-6-fluoro-3,4-dihydro-2-methyl-1(2H)-quinolinecarboxaldehyde; CGS21680; 2-[p-(2-carboxyethy

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2018 سفارش ترجمه

A monoclonal antibody raised against a thermo-stabilised β1-adrenoceptor interacts with extracellular loop 2 and acts as a negative allosteric modulator of a sub-set of β1-adrenoceptors expressed in stable cell lines

Keywords: Alprenolol (Pubchem CID: 2119); CGP 12177 (Pubchem CID: 2687); CGP 20712A (Pubchem CID: 2685); Cimaterol (Pubchem CID: 2755); Furimazine (Pubchem CID: 219083); Hoechst 33342 (Pubchem CID: 1464); IBMX (Pubchem CID: 3758); ICI 118551 (Pubchem CID: 5484725);

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2018 سفارش ترجمه

Identification of Variants in RET and IHH Pathway Members in a Large Family With History of Hirschsprung Disease

Keywords: ENS; Neural Development; Genetic Causes of HSCR; Family Study; bp; base pair; ENS; enteric nervous system; GDNF; glial cell-derived neurotrophic factor; GFP; green fluorescent protein; GLI1; GLI family zinc finger 1; GLI3; GLI family zinc finger 3; HEK;

دانلود رایگان متن کامل مقاله ISI 55 صفحه سال انتشار : 2018 سفارش ترجمه

Tools and drugs for uracil nucleotide-activated P2Y receptors

Keywords: ADP; Adenosine 5′-diphosphate; AP4A; P1,P4-Di(adenosine-5′)-tetraphosphate; AR; Adenosine receptor; AR-C118925; 5-{[5-(2,8-Dimethyl-5H-dibenzo[a,d]cyclohepten-5-yl)-3,4-dihydro-2-oxo-4-thioxo-1(2H)-pyrimidinyl]methyl}-N-(1H-tetrazol-5-yl)-2-furancarbo

دانلود رایگان متن کامل مقاله ISI 193 صفحه سال انتشار : 2018 سفارش ترجمه

Attachment of a 'molecular spring' restores drug-stimulated ATPase activity to P-glycoprotein lacking both Q loop glutamines

Keywords: P-glycoprotein; ABC protein; Disulfide cross-linking; Molecular spring; Drug-stimulated ATPase activity; ABC; ATP-binding cassette; P-gp; P-glycoprotein; NBD; nucleotide-binding domain; HEK; human embryonic kidney; TM; transmembrane; TMD; transmembrane do

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

Research paperDetection of potassium channel KIR4.1 antibodies in Multiple Sclerosis patients

Keywords: CRESM; Regional Referring Multiple Sclerosis Centre; NICO; Neuroscience Institute Cavalieri Ottolenghi; KIR4.1; inward-rectifying potassium channel 4.1; MS; multiple sclerosis; LG-KIR4.1; lower-glycosylated KIR4.1; HEK; human embryonic kidney; ELISA; enzy

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Interaction of FAM5C with UDP-glucose:glycoprotein glucosyltransferase 1 (UGGT1): Implication of N-glycosylation in FAM5C secretion

Keywords: FAM5C; BRINP3; UGGT1; N-glycosylation; Endothelial cells; BRINP; bone morphogenetic protein and retinoic acid-inducible neural specific protein; DMEM; Dulbecco's modified medium; ECs; endothelial cells; ER; endoplasmic reticulum; G-I; glucosidase I; G- II

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Original articlePharmacological effects of β-d-mannuronic acid (M2000) on miR-146a, IRAK1, TRAF6 and NF-κB gene expression, as target molecules in inflammatory reactions

Keywords: ANOVA; analysis of variance; CCL-8; chemokine (C-C motif) ligand 8; CO2; carbon dioxide; FADD; fas-associated protein with death domain; HEK; human embryonic kidney; IRAK1; interleukin-1 receptor-associated kinase 1; IRF5; interferon regulatory factor 5;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Down-regulation of Kir2.6 channel by c-termini mutation D252N and its association with the susceptibility to Thyrotoxic Periodic Paralysis

Keywords: EGTA; ethylene glycol-bis(β-aminoethyl ether)-N,N,N′,N′-tetraacetic acid; HEK; Human embryonic kidney; Hepes; 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid; TPP; Thyrotoxic Periodic Paralysis; TREs; thyroid hormone response elements; TSH; t

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Gain-of-function mutation in SCN5A causes ventricular arrhythmias and early onset atrial fibrillation

Keywords: SCN5A; the gene encoding the α-subunit of the cardiac sodium channel; NaV1.5; cardiac sodium channel; AF; atrial fibrillation; AP; action potential; ECG; electrocardiogram; HEK; human embryonic kidney cell; INa; voltage gated sodium current; MRI; magneti

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

A short cross-linker activates human P-glycoprotein missing a catalytic carboxylate

Keywords: 1, 10-Phenanthroline (PubChemSID: 24278); Cyclosporine A (PubChemCID: 5284373); Verapamil hydrochloride (PubChemCID: 62969); Vinblastine (PubChemCID: 241903); n-dodecyl-β-D-maltoside (PubChemCID: 114880); ABC; ATP-binding cassette; P-gp; P-glycoprotein;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

The efficacy of Dynorphin fragments at the κ, μ and δ opioid receptor in transfected HEK cells and in an animal model of unilateral peripheral inflammation

Keywords: FCA; Freund's Complete Adjuvant; KOP; κ-opioid receptor; MOP; μ-opioid receptor; DOP; δ-opioid receptor; HEK; human embryonic kidney 293; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; BSA; bovine serum albumin; Dynorphin; cAMP; Opioid re

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

The binding orientation of epibatidine at α7 nACh receptors

Keywords: Cys-loop; Ion channel; Radioligand; Epibatidine; Agonist; α7 nACh; Nicotinic; Receptor; AChBP; 5-HT; 5-hydroxytryptamine; nACh; nicotinic acetylcholine; GABA; gamma-aminobutyric acid; HEK; human embryonic kidney; AChBP; acetylcholine binding protein; 5HT

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

High-level expression and purification of soluble form of human natural killer cell receptor NKR-P1 in HEK293S GnTI− cells

Keywords: NKR-P1; CD161; klrb1; NK cells; HEK293; LLT1; CTL; C-type lectin-like; GnTI−; N-acetylglucosaminyltransferase I negative; HEK; human embryonic kidney; LLT1; lectin-like transcript 1; lPEI; linear polyethylenimine; MALS; multi-angle light scattering; NK;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Polyglutamine expansion of ataxin-3 alters its degree of ubiquitination and phosphorylation at specific sites

Keywords: Ataxin-3; Spinocerebellar ataxia type 3; Mass spectrometry; Neurodegeneration; Ubiquitination; Phosphorylation; DUB; deubiquitinating enzyme;; HD; Huntington's disease; HEK; human embryonic kidney;; LC-MS/MS; liquid chromatography tandem mass spectrometry

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

E2F6 protein levels modulate drug induced apoptosis in cardiomyocytes

Keywords: α-mhc; α-myosin heavy chain; β2-AR; beta-2-adrenergic receptor; Bax; Bcl2 associated protein X; Bcl2; B-cell lymphoma 2; Blm2; bloom syndrome 2 homolog; Bnip3; Bcl2 interacting protein 3; Chk1; checkpoint kinase 1; c-src; proto-oncogene tyrosine protei

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Transcriptional regulation of the sodium channel gene (SCN5A) by GATA4 in human heart

Keywords: ChIP; chromatin immunoprecipitation; cRNA; complementary RNA; ddPCR; droplet digital PCR; GATA-BS; GATA binding sites; HEK; human embryonic kidney; Re-ChIP; sequential ChIP; NaV1.5; sodium channel, voltage-gated, type V alpha subunit; TSS; transcription s

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

The endocytic pathways of a secretory granule membrane protein in HEK293 cells: PAM and EGF traverse a dynamic multivesicular body network together

Keywords: CSFM; complete serum-free medium; EGF; epidermal growth factor; HEK; human embryonic kidney; HSG; HEPES-buffered saline with glucose; ILV; intralumenal vesicle; MPR; mannose-6-phosphate receptor; PAM; peptidylglycine α-amidating monooxygenase; PAL; pepti

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Optogenetic Control of Ca2 + and Voltage-Dependent Large Conductance (BK) Potassium Channels

Keywords: ChR; channelrhodopsin; CatCh; Calcium translocating Channelrhodopsin; BK; Big Potassium; HEK; human embryonic kidney; BAPTA; 1,2-bis(o-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid; Cav; voltage-gated calcium; optogenetics; BK channel; channelrhodops

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Differential cytotoxicity and intracellular calcium-signalling following activation of the calcium-permeable ion channels TRPV1 and TRPA1

Keywords: DRG; dorsal root ganglion neuron; TRP; transient receptor potential; ER; endoplasmic reticulum; AITC; allyl isothiocyanate; HEK; human embryonic kidney; BCTC; 4-(3-Chloro-2-pyridinyl)-N-[4-(1,1-dimethylethyl)phenyl]-1-piperazinecarboxamide; BABTA; 1,2-Bis

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

The binding orientations of structurally-related ligands can differ; A cautionary note

Keywords: Cys-loop; Ion channel; Receptor; Radioligand; 5-HT3; Agonist; Antagonist; Crystal; Binding; Granisetron; Tropisetron; Ligand; Structure; Synthesis; 5-HT; 5-hydroxytryptamine; nACh; nicotinic acetylcholine; GABA; gamma-aminobutyric acid; HEK; human embryon

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

The effects of RAMPs upon cell signalling

Keywords: Receptor activity modifying protein; G protein-coupled receptor; Signalling; Trafficking; Coupling; AM; adrenomedullin; AMY; amylin; CaSR; calcium-sensing receptor; CGRP; calcitonin gene-related peptide; CHO; chinese hamster ovary; CLR; calcitonin recepto

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2017 سفارش ترجمه

Histone methyltransferase SETDB1 maintains survival of mouse spermatogonial stem/progenitor cells via PTEN/AKT/FOXO1 pathway

Keywords: SETDB1; set domain, bifurcated 1; H3K9; histone H3 lysine 9; SSCs; spermatogonial stem cells; GDNF; glial cell line-derived neurotrophic factor; SFK; Src family kinase; PI3K; phosphatidylinositol 3-kinase; ESCs; embryo stem cells; DMEM/F12; Modified Eagle

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2017 سفارش ترجمه

Thiol-reactive drug substrates of human P-glycoprotein label the same sites to activate ATPase activity in membranes or dodecyl maltoside detergent micelles

Keywords: P-glycoprotein drug-binding sites; ABC protein; n-Dodecyl-β-D-maltoside detergent; Tariquidar; Thiol reactive verapamil and rhodamine; ABC; ATP-binding cassette; DM; n-dodecyl-β-D-maltoside; P-gp; P-glycoprotein; NBD; nucleotide-binding domain; HEK; hum

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2017 سفارش ترجمه

The multi-site docking protein Gab1 is constitutively phosphorylated independent from its recruitment to the plasma membrane in Jak2-V617F-positive cells and mediates proliferation of human erythroleukaemia cells

Keywords: AEBSF; 4-(2-aminoethyl)-benzolsulfonylfluorid; DMEM; Dulbecco's modified Eagle's medium; EGFR; epidermal growth factor receptor; Epo; erythropoietin; EpoR; erythropoietin receptor; Erk; extracellular signal regulated kinase; FCS; fetal calf serum; Gab1; G

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

The yeast Ste2p G protein-coupled receptor dimerizes on the cell plasma membrane

Keywords: BiFC; bimolecular fluorescence complementation; BRET; bioluminescence resonance energy transfer; C-EGFP; C-terminal domain of enhanced green protein; EGFP; enhanced green fluorescent protein; ER; endoplasmic reticulum; FRET; Förster resonance energy tran

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2017 سفارش ترجمه

Stress Signals, Mediated by Membranous Glucocorticoid Receptor, Activate PLC/PKC/GSK-3β/β-catenin Pathway to Inhibit Wound Closure

Keywords: CC; calphostin C; Dex; dexamethasone; Dex-BSA; BSA-conjugated dexamethasone; GC; glucocorticoid; GR; glucocorticoid receptor; GILZ; glucocorticoid response element-induced leucine zipper; GSK-3β; glycogen synthase kinase 3 beta; HEK; human keratinocyte

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2017 سفارش ترجمه

Lysophosphatidylcholine export by human ABCA7

Keywords: Aβ; amyloid β; ABC; ATP-binding cassette; AD; Alzheimer's disease; apoA-I; apolipoprotein A-I; apoE; apolipoprotein E; APP; amyloid precursor protein; BHK; baby hamster kidney; BSA; bovine serum albumin; DMEM; Dulbecco's modified Eagle's medium; GFP; gr

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه