دانلود مقالات ISI درباره Hek + ترجمه فارسی

N-glycosylation and disulfide bonding affects GPRC6A receptor expression, function, and dimerization

Keywords: BSA; bovine serum albumin; CRD; cysteine-rich domain; dFBS; dialyzed fetal bovine serum; DPBS; Dulbecco's Phosphate-Buffered Saline; DTT; dithiothreitol; ECD; extracellular domain; ELISA; Enzyme-Linked Immunosorbent Assay; ER; endoplasmic reticulum; EtO

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Site-specific structural characterization of O-glycosylation and identification of phosphorylation sites of recombinant osteopontin

Keywords: OPN; osteopontin; PTM; post-translational modification; O-GlcNAc; O-linked β-N-acetylglucosamine; MALDI-TOF; matrix-assisted laser desorption ionization-time of flight; MS; mass spectrometry; PMF; peptide mass fingerprint; MS/MS; tandem mass spectrometry

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Cellulose alters the expression of nuclear factor kappa B-related genes and Toll-like receptor-related genes in human peripheral blood mononuclear cells

Keywords: ATM; ataxia telangiectasia mutated; AUC; area under the curve; CD; cluster of differentiation; ECIS; electric cell substrate impedance sensing; EU; endotoxin units; FBS; foetal bovine serum; HEK; human embryonic kidney; IL-1Ra; interleukin 1 receptor anta

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

MAPK-induced Gab1 translocation to the plasma membrane depends on a regulated intramolecular switch

Keywords: Crk; CT10 regulator of kinase; CRKL; Crk-like protein; ERK; extracellular signal regulated kinase; FCS; foetal calf serum; Gab1; Grb2-associated binder 1; Grb2; growth factor receptor bound protein 2; IL-6; interleukin-6; JAK; Janus kinase; HEK; human emb

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Effects of AP39, a novel triphenylphosphonium derivatised anethole dithiolethione hydrogen sulfide donor, on rat haemodynamic parameters and chloride and calcium Cav3 and RyR2 channels

Keywords: ADT-OH; anethole dithiolethione, 5-[p-methoxyphenyl]3H-1,2-dithiole-3-thione; AP219; 9-(Carboxynonyl)triphenylphosphonium bromide; AP39; (10-oxo-10-(4-(3-thioxo-3H-1,2-dithiol-5-yl)phenoxy)decyl)triphenylphosphonium bromide; ApoE; apolioprotein E; ARRIVE;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Optimising methods for the preservation, capture and identification of ubiquitin chains and ubiquitylated proteins by immunoblotting

Keywords: Ubiquitin; Ubiquitin-binding-domain; Immunoblotting; Deubiquitylase; Ubiquitin chain topology; DMP; dimethyl pimelidinate; DUB; deubiquitylase; GST; glutathione S-transferase; HEK; human embryonic kidney; IAA; iodoacetamide; IL-1R; IL-1 receptor; IMAC; im

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Downregulation of kinin B1 receptor function by B2 receptor heterodimerization and signaling

Keywords: kB1R; kinin B1 receptor; kB2R; bradykinin B2 receptor; GPCR; G protein-coupled receptor; BK; bradykinin; KD; kallidin; DABK; des-Arg9-bradykinin; DAKD; des-Arg10-kallidin; LV; left ventricular; ACE; angiotensin I converting enzyme; DMEM; Dulbecco's Modifi

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Space experiment “Cellular Responses to Radiation in Space (CellRad)”: Hardware and biological system tests

Keywords: ATM; Ataxia telangiectasia mutated; CellRad; Cellular Responses to Radiation in Space; CMV; cytomegalovirus; d2EGFP; destabilized variant of EGFP; DDR; DNA damage response; DSB; double strand breaks; DLR; German Aerospace Center; DMSO; dimethyl sulfoxide;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

A subset of N-substituted phenothiazines inhibits NADPH oxidases

Keywords: CHO; Chinese hamster ovary; DMSO; dimethyl sulfoxide; DUOX; dual oxidase; DMEM; Dulbecco׳s modified Eagle medium; DPI; diphenyleneiodonium; ESP; electrostatic potential; FBS; fetal bovine serum; GFP; green fluorescent protein; HBSS; Hanks׳ buffered salt

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2015 سفارش ترجمه

Synthesis and biological evaluation of 3-phenethylazetidine derivatives as triple reuptake inhibitors

Keywords: 5-HT; serotonin; NE; norepinephrine; DA; dopamine; SSRI; selective serotonin reuptake inhibitor; SNRI; serotonin norepinephrine reuptake inhibitor; TRI; triple reuptake inhibitor; CYP; cytochrome P450; hERG; human ether-a go-go-related gene; HEK; human em

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

An ATPase inhibitory peptide with antibacterial and ion current effects

Keywords: CFU; colony forming units; HEK; human embryo-kidney; MBC; minimum bactericidal concentration; PSK; Peptide Ser Lys; ATPase inhibitory peptide; Glycine-rich antibacterial peptide; Pancreatic β cell; Cellular cation current; Chrysomya megacephala peptide s

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

A salt bridge between Arg-20 on parathyroid hormone (PTH) and Asp-137 on the PTH1 receptor is essential for full affinity

Keywords: PTH; parathyroid hormone; PTHrP; parathyroid hormone-related peptide; 125I-rPTH(1-34); 125I-[Nle8,21,Tyr34]rPTH(1-34)NH2; MBS; membrane binding solution; GPCR; G protein-coupled receptor; N domain; N-terminal extracellular domain; PTH1; PTH/PTHrP rece

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Nonsense-mediated mRNA decay due to a CACNA1C splicing mutation in a patient with Brugada syndrome

Keywords: BrS; Brugada syndrome; cDNA; complementary DNA; ECG; electrocardiogram; HEK; human embryo kidney; hERG; human ether-à-go-go-related gene; ICa; calcium current; ICD; implantable cardioverter-defibrillator; mRNA; messenger RNA; NMD; nonsense-mediated mRN

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

GGA1 overexpression attenuates amyloidogenic processing of the amyloid precursor protein in Niemann-Pick type C cells

Keywords: Aβ; amyloid beta peptide; AD; Alzheimer's disease; ADAM; A disintegrin and metalloproteinase; APOE; apolipoprotein E; APP; amyloid precursor protein; BACE1; beta-secretase; CHO; Chinese hamster ovary; CTF; C-terminal fragment; DN; dominant negative; FA

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

RacGTPase-activating protein 1 interacts with hepatitis C virus polymerase NS5B to regulate viral replication

Keywords: CE; cell extract; co-IP; coimmunoprecipitation; DMEM; Dulbecco's modified Eagle's medium; dsRNA; double-stranded RNA; FBS; fetal bovine serum; FFU; focus-forming units; GAP; GTPase activating protein; GFP; green fluorescent protein; HEK; human embryo

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Mechanisms that underlie the internalization and extracellular signal regulated kinase 1/2 activation by PKR2 receptor

Keywords: AT1AR; angiotensin type 1A receptor; ConA; Concanavalin A; DN-GRK; dominant-negative G-protein-coupled receptor kinase 2; EGFP; enhanced green fluorescent protein; ERK; extracellular signal regulated kinase; GPCR; G-protein-coupled receptors; GRK; GPCR ki

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Mislocalization of K+ channels causes the renal salt wasting in EAST/SeSAME syndrome

Keywords: Epithelial sodium transport; EAST/SeSAME syndrome; Intracellular trafficking; Kidney; Potassium channel; Tubulopathy; Kir; inwardly rectifying K+ channel; DCT; distal convoluted tubule; GFP; green fluorescent protein; HEK; human embryonic kidney; NCC; Na+

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

TLR7/8 agonists activate a mild immune response in rabbits through TLR8 but not TLR7

Keywords: TLR; toll-like receptor; TIR; toll-interlerkin 1 receptor; LRR; leucine-rich repeats; NF-κB; nuclear factor-κB; IRF7; interferon regulatory factor 7; MyD88; myeloid differentiation factor 88; HEK; human embryonic kidney; FCS; fetal calf serum; PBS; phos

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Targeting kidney CLC-K channels: Pharmacological profile in a human cell line versus Xenopus oocytes

Keywords: NFA; niflumic acid; HEK; human embryonic kidney; MDCK; Madin Darby Canine Kidney; ATP; adenosine 5′-triphosphate; DCT; distal convoluted tubule; CLC-K chloride channel; Kidney; Pharmacology; HEK293 cell; Bartter syndrome; Hypertension;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

LC-MS/MS characterization of combined glycogenin-1 and glycogenin-2 enzymatic activities reveals their self-glucosylation preferences

Keywords: CID; collision-induced dissociation; DTT; dithiothreitol; ECD; electron capture dissociation; Glc; glucose; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; HEK; Human Embryonic Kidney; LC; liquid chromatography; MS; mass spectrometry; PAS; peri

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Pharmacological profiles of aminoindanes, piperazines, and pipradrol derivatives

Keywords: Novel psychoactive substance; Monoamine; Transporter; Receptor; 2-AI; 2-aminoindane; BZP; 1-benzylpiperazine; DA; dopamine; DAT; dopamine transporter; D2PM; diphenyl-2-pyrrolidinemethanol; 2-DPMP; desoxypipradrol or 2-diphenylmethylpiperidine; HEK; human

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Potential roles of PINK1 for increased PGC-1α-mediated mitochondrial fatty acid oxidation and their associations with Alzheimer disease and diabetes

Keywords: PGC-1α; peroxisome proliferator-activated receptor-gamma co-activator 1α; PINK1; PTEN-induced putative kinase 1; AD; Alzheimer disease; PD; Parkinson disease; HD; Huntington disease; ALS; amyotrophic lateral sclerosis; STZ; streptozotocin; HEK; human em

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

P2X7 receptors mediate resistance to toxin-induced cell lysis

Keywords: HEK; human embryonic kidney 293 cells; HMC-1; human mast cell line 1; P2X7R; P2X7 receptor; RT; room temperature; SLO; streptolysin O; P2X7; Plasmalemma; Blebbing; Calcium; Lysis; Annexin;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

mTOR and autophagy: A dynamic relationship governed by nutrients and energy

Keywords: Akt1; v-akt murine thymoma viral oncogene homolog 1; AMBRA; Autophagy/Beclin-1 regulator 1; AMPK; AMP-dependent protein kinase; ATG; autophagy-related; BECN1; beclin 1; DEPTOR; DEP domain containing mTOR-interacting protein; EGFR; epidermal growth factor

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Biophysical characterization of sites of host adaptive mutation in the influenza A virus RNA polymerase PB2 RNA-binding domain

Keywords: ATCC; American Type Culture Collection; EMSA; electrophoretic mobility shift assays; FAM; fluorescein amidite; FLuc; firefly luciferase; HEK; human embryonic kidney; NMR; nuclear magnetic resonance; RdRp; RNA-dependent RNA polymerase; RLuc; Renilla lucife

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

The conserved sumoylation consensus site in TRIM5α modulates its immune activation functions

Keywords: CA; capsid; HEK; human embryonic kidney; HTLV; human T-cell leukemia virus; IF; immunofluorescence; IP; immunoprecipitation; LMB; leptomycin B; MOI; multiplicity of infection; NB; nuclear body; PBS; phosphate buffer saline; PML; promyelocytic leukemia; SU

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

TRAF-mediated modulation of NF-kB AND JNK Activation by TNFR2

Keywords: AIP1; ASK1 interacting protein; AP-1; activating protein 1; BKO; binding knock out; CRMA; cytokine response modifier A; cIAP; cellular inhibitor of apoptosis; DMEM; Dulbecco modified Eagle's medium; FLAG; FLAG peptide; HA; hemagglutinin; HEK; human embryo

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Pericytes prevent regression of endothelial cell tubes by accelerating metabolism of lysophosphatidic acid

Keywords: AMD; age-related macular degeneration; ATX; autotaxin; BREC; bovine retinal endothelial cell; BRP; bovine retinal pericyte; EC; endothelial cell; HEK; HEK293 (human embryonic kidney) cell; HUVEC; human umbilical vein endothelial cell; LPA; lysophosphatidi

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Functional interaction of the cystic fibrosis transmembrane conductance regulator with members of the SLC26 family of anion transporters (SLC26A8 and SLC26A9): Physiological and pathophysiological relevance

Keywords: cAMP; cyclic adenosine monophosphate; CF; cystic fibrosis; CFBE4Io-; cystic fibrosis bronchial epithelial cell line; CFTR; cystic fibrosis transmembrane conductance regulator; CHO-K1; Chinese hamster ovary-K1; DHPLC; denaturing high performance liquid chr

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Probing biased/partial agonism at the G protein-coupled A2B adenosine receptor

Keywords: GPCR; Adenosine receptor; Purines; Cyclic AMP; Calcium; Arrestin; BAY60-6583 (BAY, LUF6210); 2-[[6-amino-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]-2-pyridinyl]thio]acetamide; cyclic AMP (cAMP); 3′5′-cyclic adenosine monophosphate; CGS21680; 2-[p-(2

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Aspp2 negatively regulates body growth but not developmental timing by modulating IRS signaling in zebrafish embryos

Keywords: aa; amino acids; Akt/PKB; protein kinase B; Ank; ankyrin repeats; AO; Acridine orange; BrdU; 5-bromo-2′-deoxyuridine; EGFP; enhanced GFP; Erk; extracellular signal-regulated kinases; HEK; human embryonic kidney; hpf; hour post fertilization; IGF-IR; IGF

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

GCK-MODY diabetes as a protein misfolding disease: The mutation R275C promotes protein misfolding, self-association and cellular degradation

Keywords: BCA; bicinchoninic acid; DMEM; dulbecco's modified eagles medium; GCK; glucokinase gene; Glc; α-D-glucose; GKRP; glucokinase regulatory protein; HEK; human embryonic kidney; hGK; human glucokinase; IFG; impaired fasting glucose; MIN; mouse insulinoma;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

The binding characteristics and orientation of a novel radioligand with distinct properties at 5-HT3A and 5-HT3AB receptors

Keywords: Antagonist; Cys-loop; Ion channel; Radioligand; 5-HT3; Agonist; 5-HT; 5-hydroxytryptamine; nACh; nicotinic acetylcholine; GABA; gamma-aminobutyric acid; HEK; human embryonic kidney; AChBP; acetylcholine binding protein; 5HTBP; an AChBP mutant modified to

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Functional assessment of the mutational effects of human IRAK4 and MyD88 genes

Keywords: DD; death domain; HEK; human embryonic kidney; ID; internal domain; IRAK; Interleukin-1 receptor-associated kinase; MyD88; myeloid differentiating factor 88; Mal; MyD88 adaptor-like; NMR; nuclear magnetic resonance; ELISA; enzyme-linked immunosorbent assa

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

A subset of chicken statoacoustic ganglion neurites are repelled by Slit1 and Slit2

Keywords: CMV; cytomegalovirus; CNTF; Ciliary Neurotrophic Factor; df; degrees of freedom; E; embryonic day; EF-1α; elongation factor 1 alpha; GFP; green fluorescent protein; HBSS; Hank's Balanced Salt Solution; HEK; human embryonic kidney; HH; Hamburger and Hamil

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Differential requirements of arrestin-3 and clathrin for ligand-dependent and -independent internalization of human G protein-coupled receptor 40

Keywords: LA; linoleic acid; LNA; linolenic acid; GPCR; G-protein coupled receptor; HEK; human embryonic kidney; cAMP; cyclic AMP; siRNA; small interfering RNA; shRNA; small hairpin RNA; Rab; ras-related GTP-binding protein; BSA; bovine serum albumin; GRKs; G prote

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Caveolin-1 interacts with ATP binding cassette transporter G1 (ABCG1) and regulates ABCG1-mediated cholesterol efflux

Keywords: ABC; ATP-binding cassette transporter; AcLDL; acetylated LDL; apo; apolipoprotein; BSA; bovine serum albumin; CAV1; caveolin-1; CL; cytoplasmic loop; DAPI; 4′,6-diamidino-2-phenylindole; DMEM; Dulbecco's modified Eagle's medium; EGFR; epidermal growth f

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Activation of Bombyx neuropeptide G protein-coupled receptor A4 via a Gαi-dependent signaling pathway by direct interaction with neuropeptide F from silkworm, Bombyx mori

Keywords: Neuropeptide; GPCR; Signaling; Arrestin; MAP kinases; AKH; adipokinetic hormone; cAMP; cyclic AMP; CRE; cAMP-response element; EGFP; enhanced green fluorescent protein; ERK1/2; extracellular signal-regulated kinase1/2; Gi; inhibitory GTP-binding protein o

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

MicroRNA-150 regulates the cytotoxicity of natural killers by targeting perforin-1

Keywords: miR-150; NK cells; perforin-1; NK cell cytotoxicity; post-transcriptional regulation; immunotherapy; tumor growth and metastasis; AANAT; Aralkylamine N-acetyltransferase; DMEM; Dulbecco modified Eagle medium; E/T; Effector/target; GAPDH; Glyceraldehyde-3-

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

A survey of detergents for the purification of stable, active human cystic fibrosis transmembrane conductance regulator (CFTR)

Keywords: CF; cystic fibrosis; CFTR; cystic fibrosis transmembrane conductance regulator; CMC; critical micelle concentration; DTT; dithiothreitol; EM; electron microscopy; GFP; green fluorescent protein; HEK; human embryonic kidney cells; Inh172; CFTR Inhibitor 17

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Activation of c-Src: A hub for exogenous pro-oxidant-mediated activation of Toll-like receptor 4 signaling

Keywords: ONS; oxidative/nitrosative stress; TLR; Toll-like receptor; HEK; human embryonic kidney; MD; myeloid of differentiation; Ca-pY; caffeic acid-pYEEIE; CD; cluster of differentiation; Eb; ebselen; MPLA; monophosphoryl lipid A; LPS-EK; lipopolysaccharide

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

TET enzymatic oxidation of 5-methylcytosine, 5-hydroxymethylcytosine and 5-formylcytosine

Keywords: α-KG; α-ketoglutarate; AML; acute myeloid leukemia; APOBEC; apolipoprotein B mRNA-editing enzyme complex; ARP; aldehyde reactive probe; β-GT; β-glucosyl transferase; 5-caC; 5-carboxylcytosine; 5-cadCyd; 5-carboxyl-2′-deoxycytidine; C; cytosine; C5-M

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2014 سفارش ترجمه

TRIM39R, but not TRIM39B, regulates type I interferon response

Keywords: BD; Behcet's disease; HLA; human leukocyte antigen; GWAS; genome-wide association study; IL; interleukin; TRIM; tripartite moti; LD; linkage disequilibrium; HEK; human embryonic kidney; PVDF; polyvinylidene difluoride; TBST; Tris-buffered saline contain

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Amino acid residues at the N- and C-termini are essential for the folding of active human butyrylcholinesterase polypeptide

Keywords: AChE; acetylcholinesterase; BHK; baby hamster kidney cells; BTC; butyrylthiocholine iodide; ChE; cholinesterase; CHO; Chinese hamster ovary cells; DTNB; 5,5′-dithiobis 2-nitrobenzoic acid; HBP; HuBChE polypeptide; HEK; human embryonic kidney cells; HuBC

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Agonists and antagonists induce different palonosetron dissociation rates in 5-HT3A and 5-HT3AB receptors

Keywords: Serotonin receptor; Allosteric binding site; Site-directed mutagenesis; Radioligand binding; FlexStation assays; 5-HT; 5-hydroxytryptamine (serotonin); HEK; human embryonic kidney; IC50; concentration of antagonist required for half-maximal inhibition; Kd

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Exploring a potential palonosetron allosteric binding site in the 5-HT3 receptor

Keywords: 5-HT; 5-hydroxytryptamine (serotonin); EC50; concentration of agonist required for half-maximal response; HEK; human embryonic kidney; IC50; concentration of antagonist required for half-maximal inhibition; Kd; affinity constant; Serotonin receptor; Allos

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Delineation of the TRAK binding regions of the kinesin-1 motor proteins

Keywords: FEZ1; fasciculation and elongation protein-ζ; FRET; Forster resonance energy transfer; GRIP; glutamate receptor-interacting protein 1; HAP1; Huntingtin-associated protein; HEK; human embryonic kidney; MADD; adaptor protein mitogen-activated protein kinas

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Down-regulation of LRRK2 in control and DAT transfected HEK cells increases manganese-induced oxidative stress and cell toxicity

Keywords: LRRK2; leucine-rich repeat kinase 2; DAT; dopamine transporter; DA; dopamine; Mn; manganese; HEK; human embryonic kidney; ROS; reactive oxygen species; JNK; c-Jun N-terminal kinases; p38; 38 mitogen-activated protein kinase; AP13A2; probable cation-transp

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

The TRPM4 non-selective cation channel contributes to the mammalian atrial action potential

Keywords: AP; action potential; APA; action potential amplitude; APD; action potential duration; ER; reversal potential; FFA; flufenamic acid; H-89; N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamidedihydrochloride hydrate; g; single channel conductance; H

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Oral treatment with a novel small molecule alpha 4 integrin antagonist, AJM300, prevents the development of experimental colitis in mice

Keywords: IBD; inflammatory bowel disease; AJM300; orally active small molecule α4 integrin antagonist; AJM300M1; a special formulation containing AJM300 at approximately 43% and excipients: AJM300M1 preparation; VCAM-1; vascular cell adhesion molecule-1; MAdCAM-1

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه