دانلود مقالات ISI درباره hepatocytes + ترجمه فارسی

Creatine reduces hepatic TG accumulation in hepatocytes by stimulating fatty acid oxidation

Keywords: hepatocytes; ABCA1; ATP binding cassette protein; AMPK; adenosine monophosphate-activated protein kinase; CT; CTP:phosphocholine cytidylyltransferase; DGAT; acyl CoA:diacylglycerol acyltransferase; HDL; high density lipoproteins; HFD; high-fat diet; HCD; high-carbohyd

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Identification of Primary Equilibrative Nucleoside Transporter 1 mRNA Isoforms Resulting from Alternative Promoter Usage in Human Hepatocytes

Keywords: hepatocytes; equilibrative nucleoside transporter; SLC29A1; alternative promoter; 5′-untranslated region; hepatocytes; gene expression; human

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Combined use of N-acetylcysteine and Liberase improves the viability and metabolic function of human hepatocytes isolated from human liver

Keywords: hepatocytes; acetylcysteine; cell transplantation; hepatocytes; Liberase;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Ascorbic acid suppresses endotoxemia and NF-κB signaling cascade in alcoholic liver fibrosis in guinea pigs: A mechanistic approach

Keywords: hepatocytes; Alcohol; Ascorbic acid; Guinea pigs; Hepatocytes; Liver toxicity;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Preparation and characterization of galactosylated alginate-chitosan oligomer microcapsule for hepatocytes microencapsulation

Keywords: hepatocytes; Galactosylated alginate; Microcapsule; Mechanical stability; Selective permeability; Microenvironment; Hepatocytes;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

A Novel Strategy for ADME Screening of Prodrugs: Combined Use of Serum and Hepatocytes to Integrate Bioactivation and Clearance, and Predict Exposure to Both Active and Prodrug to the Systemic Circulation

Keywords: hepatocytes; prodrug; active drug; screening strategy; serum; hepatocytes; absorption; bioavailability; in vitro models; exposure;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Evaluation of the use of imaging parameters for the detection of compound-induced hepatotoxicity in 384-well cultures of HepG2 cells and cryopreserved primary human hepatocytes

Keywords: hepatocytes; Hepatotoxicity; Imaging; Metabolism; Hepatocytes;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Hepatitis B virus preS1-derived lipopeptide functionalized liposomes for targeting of hepatic cells

Keywords: hepatocytes; Hepatitis B virus; Targeted drug delivery; Liver; Liposomes; Hepatocytes

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Integration of pharmacokinetic and NRF2 system biology models to describe reactive oxygen species production and subsequent glutathione depletion in liver microfluidic biochips after flutamide exposure

Keywords: hepatocytes; Nrf2 systems biology modeling; Pharmacokinetic modeling; Microfluidic biochips; Hepatocytes; Flutamide;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Nanosilver cytotoxicity in rainbow trout (Oncorhynchus mykiss) erythrocytes and hepatocytes

Keywords: hepatocytes; Rainbow trout; Nanomaterials; Nanosilver toxicity; Ionic silver toxicity; Erythrocytes; Hepatocytes; Cysteine; Buthionine sulfoximine;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Bioreactor technologies to support liver function in vitro

Keywords: hepatocytes; Tissue engineering; Bioreactor; Microfluidic; Organ on chip; Hepatocytes; Liver non-parenchymal cells; Drug development; Drug toxicity

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2014 سفارش ترجمه

GSSG/GSH ratios in cryopreserved rat and human hepatocytes as a biomarker for drug induced oxidative stress

Keywords: hepatocytes; CE; collision energy; CM; carboxymethyl; CsA; cyclosporin A; CXP; collision cell exit potential; DMSO; dimethyl sulphoxide; DP; declustering potential; DTNB or Ellman's reagent; 5,5′-dithiobis-(2-nitrobenzoic acid); ESI; electrospray ionization; FBS;

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2014 سفارش ترجمه

Induction of ABCA1 and ABCG1 expression by the liver X receptor modulator cineole in macrophages

Keywords: hepatocytes; Cineole; Liver X receptor; Cholesterol; Macrophage; Hepatocytes;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Effects of estradiol on the endocytic transport of vitamin D carrier protein in hepatocytes

Keywords: hepatocytes; Estradiol; Endocytosis; Nutrient-carrier proteins; Hepatocytes; Vitamin D-binding protein; Fulvestrant;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Preservation, induction or incorporation of metabolism into the in vitro cellular system − Views to current opportunities and limitations

Keywords: hepatocytes; Xenobiotic metabolism; Metabolic competence; In vitro cellular systems; Hepatocytes; Cell lines;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Analysis of DNA methylation change induced by Dnmt3b in mouse hepatocytes

Keywords: hepatocytes; Dnmt; DNA methyltransferase; Gpam; glycerol-3-phosphate acyltransferase 1; MIAMI; microarray-based integrated analysis of methylation by isoschizomers; DNA methylation; DNA methyltransferase; Epigenetics; Hepatocytes; Gene expression;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Disruption of polyubiquitin gene Ubc leads to defective proliferation of hepatocytes and bipotent fetal liver epithelial progenitor cells

Keywords: hepatocytes; Ub; ubiquitin; AFP; α-fetoprotein; CK-19; cytokeratin-19; FLCs; fetal liver cells; FLECs; fetal liver epithelial cells; FLEPCs; fetal liver epithelial progenitor cells; Polyubiquitin gene; Ubiquitin; Embryonic lethality; Fetal liver development; Hepatocy

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Evaluation of UGT protein interactions in human hepatocytes: Effect of siRNA down regulation of UGT1A9 and UGT2B7 on propofol glucuronidation in human hepatocytes

Keywords: hepatocytes; UDP-Glucuronosyltransferase; siRNA; Protein interactions; Hepatocytes;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Biphasic regulation of the NADPH oxidase by HGF/c-Met signaling pathway in primary mouse hepatocytes

Keywords: hepatocytes; HGF; c-Met; NADPH oxidase; Hepatocytes; ROS;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Pex11α in brown trout (Salmo trutta f. fario): Expression dynamics during the reproductive cycle reveals sex-specific seasonal patterns

Keywords: hepatocytes; Peroxins; Pex11α; PPAR; Peroxisomes; Hepatocytes; Liver; Trout; Fish;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Dichloro-dihydro-fluorescein diacetate (DCFH-DA) assay: A quantitative method for oxidative stress assessment of nanoparticle-treated cells

Keywords: hepatocytes; DCFH-DA; Hepatocytes; In vitro assays; Nanoparticles;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Resistin impairs SIRT1 function and induces senescence-associated phenotype in hepatocytes

Keywords: hepatocytes; Resistin; SIRT1; Hepatocytes; PPARα; PGC-1α; Senescence-associated β-galactosidase activity;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Carbamazepine suppresses calpain-mediated autophagy impairment after ischemia/reperfusion in mouse livers

Keywords: hepatocytes; MPT; mitochondrial permeability transition; I/R; ischemia/reperfusion; CBZ; carbamazepine; FDA; Food & Drug Administration; Atg; autophagy-related proteins; KRH; Krebs-Ringer-N-2 hydroxyethylpiperazine-N-2 ethanesulfonic acid; PI; propidium iodide; TMRM

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

3D co-culturing model of primary pancreatic islets and hepatocytes in hybrid spheroid to overcome pancreatic cell shortage

Keywords: hepatocytes; Co-culture; Pancreatic islets; Hepatocytes; Concave microwell array; Type-1 diabetes mellitus (T1DM); Islet encapsulation;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Hepatocyte Composition-Based Model as a Mechanistic Tool for Predicting the Cell Suspension: Aqueous Phase Partition Coefficient of Drugs in In Vitro Metabolic Studies

Keywords: hepatocytes; distribution; hepatocytes; liver; metabolism; metabolic clearance; unbound fraction; computational ADME; in vitro-in vivo extrapolation; IVIVE; pharmacokinetics; PBPK modeling;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Hepatoprotective mechanisms of Ageratum conyzoides L. on oxidative damage induced by acetaminophen in Wistar rats

Keywords: hepatocytes; Acetaminophen; Ageratum conyzoides; Oxidative damage; Hepatocytes;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

Coagulation factors, fibrinogen and plasminogen activator inhibitor-1, are differentially regulated by yellow fever virus infection of hepatocytes

Keywords: hepatocytes; Yellow fever virus; Asibi virus; 17-D vaccine; Hepatocytes; Fibrinogen; Plasminogen activator inhibitor-1

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Up-regulation of cyclin-E1 via proline-mTOR pathway is responsible for HGF-mediated G1/S progression in the primary culture of rat hepatocytes

Keywords: hepatocytes; Hepatocyte growth factor; Proline; Collagen synthesis; Mammalian target of rapamycin; Cyclin-E1; Hepatocytes

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Regulation of multidrug resistance protein 2 (MRP2, ABCC2) expression by statins: Involvement of SREBP-mediated gene regulation

Keywords: hepatocytes; Statin; Hepatocytes; Multidrug resistance protein 2; Sterol regulatory element-binding protein

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Nitric oxide and cell death in liver cancer cells

Keywords: hepatocytes; Liver; Cancer; Nitrosative stress; Nitric oxide; Hepatocytes; Therapy

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

The protective effect of adipose-derived stem cells against liver injury by trophic molecules

Keywords: hepatocytes; Adipose-derived stem cells; Hepatocytes; Vascular endothelial growth factor

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Chemerin is highly expressed in hepatocytes and is induced in non-alcoholic steatohepatitis liver

Keywords: hepatocytes; Fatty liver; Hepatocytes; Chemerin; Non-alcoholic steatohepatitis

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Sulfite exposure-induced hepatocyte death is not associated with alterations in p53 protein expression

Keywords: hepatocytes; Sulfite; Hepatocytes; p53; Mdm2; Bcl-2; RIP1

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Understanding glucose uptake during methionine deprivation in incubated rainbow trout (Oncorhynchus mykiss) hepatocytes using a non-radioactive method

Keywords: hepatocytes; Hepatocytes; Methionine deprivation; Glucose uptake; Glucose transporter; Mitochondrial uncoupling

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Dielectric characterization of hepatocytes in suspension and embedded into two different polymeric scaffolds

Keywords: hepatocytes; Hepatocytes; Polymeric scaffolds; Dielectric spectroscopy;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Differential regulation of drug transporter expression by all-trans retinoic acid in hepatoma HepaRG cells and human hepatocytes

Keywords: hepatocytes; Retinoic acid; Drug transporters; Hepatocytes; Regulation; RXR; RAR

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

The biochemical basis of obesity

Keywords: hepatocytes; Triglyceride; Carbohydrate; Phosphoric acids; Hydroxylamine; Hydrogen peroxide; Adipocytes; Hepatocytes

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Metabolism of Bromopride in Mouse, Rat, Rabbit, Dog, Monkey, and Human Hepatocytes

Keywords: hepatocytes; bromopride; hepatocytes; LC-MSn; high resolution mass spectrometry; biotransformation; metabolite identification;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Assessment of energetic costs of AhR activation by β-naphthoflavone in rainbow trout (Oncorhynchus mykiss) hepatocytes using metabolic flux analysis

Keywords: hepatocytes; Energetic costs; Metabolic flux analysis; β-Naphthoflavone; Hepatocytes; Rainbow trout

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Mathematical modeling of liver enzyme elevation in HIV mono-infection

Keywords: hepatocytes; HIV; Hepatocytes; ODE system; ALT elevation

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

In vitro pharmacokinetic profile of a benzopyridooxathiazepine derivative using rat microsomes and hepatocytes: Identification of phases I and II metabolites

Keywords: hepatocytes; Benzopyridooxathiazepine; Hepatocytes; Metabolism; Microsomes; Orbitrap mass spectrometry; Validation

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Investigation of the role of transporters on the hepatic elimination of an LAT1 selective inhibitor JPH203

Keywords: hepatocytes; ADME; biliary excretion; bioavailability; cancer chemotherapy; hepatocytes; transporters

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Prediction of Total Hepatic Clearance by Combining Metabolism, Transport, and Permeability Data in the In Vitro-In Vivo Extrapolation Methods: Emphasis on an Apparent Fraction Unbound in Liver for Drugs

Keywords: hepatocytes; hepatocytes; intrinsic clearance; unbound fraction; metabolism; transport; permeability; in vitro-in vivo extrapolation; in vitro-in vivo correlation; IVIVE; pharmacokinetics; physiologically based pharmacokinetics; PBPK modeling;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Targeting C-type lectin receptors with multivalent carbohydrate ligands

Keywords: hepatocytes; C-type lectin receptors; Carbohydrates; Multivalency; Glycodendrimers; Glyconanoparticles; Glycoliposomes; Dendritic cells; Macrophages; Hepatocytes; Drug delivery; Immunomodulation

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Absolute measurement of species differences in sodium taurocholate cotransporting polypeptide (NTCP/Ntcp) and its modulation in cultured hepatocytes

Keywords: hepatocytes; target proteomics; hepatic transport; hepatocytes; LC–MS/MS; NTCP; transporters

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Perspective on liver regeneration by bone marrow–derived stem cells—A scientific realization or a paradox

Keywords: hepatocytes; bone marrow–derived stem cells; cell fusion; cues; functional recovery; hepatocytes; liver regeneration; plasticity

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Toward a new paradigm for the efficient in vitro–in vivo extrapolation of metabolic clearance in humans from hepatocyte data

Keywords: hepatocytes; hepatocytes; intrinsic clearance; unbound fraction; computational ADME; in vitro–in vivo extrapolation; in vitro–in vivo correlation; IVIVE; pharmacokinetics; physiologically based pharmacokinetics; PBPK modeling

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Metabolic Characterization of Primary Rat Hepatocytes Cultivated in Parallel Microfluidic Biochips

Keywords: hepatocytes; hepatocytes; hepatic metabolism; drug delivery system; cytochrome P450; phase II metabolism; efflux pumps; in vitro models

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Pharmacokinetic Modeling of Hepatocyte Growth Factor in Experimental Animals and Humans

Keywords: hepatocytes; pharmacokinetics/pharmacodynamics; proteins; receptors; hepatic clearance; elimination; hepatocytes; distribution;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

An updated method for the isolation and culture of primary calf hepatocytes

Keywords: hepatocytes; Calf; Hepatocytes; Cell isolation; Primary culture; Hepatocyte function

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه