دانلود مقالات ISI درباره hepatocytes + ترجمه فارسی

Hepatoprotective and antioxidant potential of Asphodeline lutea (L.) Rchb. roots extract in experimental models in vitro/in vivo

Keywords: hepatocytes; Anthraquinones; Asphodeline lutea; CCl4; Cytochrome P450; Hepatocytes; Oxidative stress

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Characterization of Long-Lasting Oatp Inhibition by Typical Inhibitor Cyclosporine A and In Vitro-In Vivo Discrepancy in Its Drug Interaction Potential in Rats

Keywords: hepatocytes; drug interactions; in vitro/in vivo correlations; pharmacokinetics; protein binding; transporters; CYP enzymes; hepatocytes; organic anion-transporting polypeptide transporters; multidrug resistance transporters; solute transporters; ABT; 1-aminobenzotr

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Mechanisms of cortisol action in fish hepatocytes

Keywords: hepatocytes; Fish; Hepatocytes; Cortisol; Stress; Intermediary metabolism; Glucocorticoid signalling; Glucoregulatory hormones;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Toxicity and oxidative stress induced by T-2 toxin and HT-2 toxin in broilers and broiler hepatocytes

Keywords: hepatocytes; T-2 and HT-2 toxin; Broilers; Hepatocytes; Toxicity; Oxidative stress; T-2; T-2 toxin; HT-2; HT-2 toxin; GSH; glutathione; LDH; lacate dehydrogenase; ALT; alanine aminotransferase; AST; aspartate aminotransferase; ROS; reactive oxygen species; GSH-PX; glu

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Inhibition of bile salt transport by drugs associated with liver injury in primary hepatocytes from human, monkey, dog, rat, and mouse

Keywords: hepatocytes; Bile salt export pump; BSEP; ABCB11; Drug-induced liver injury; DILI; Bile salts; Hepatocytes; Species differenceBSEP, bile salt export pump; CA, cholic acid; CDCA, chenodeoxycholic acid; DILI, drug-induced liver injury; GCA, glycocholic acid; GCDCA, glyc

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Oxidative products from alcohol metabolism differentially modulate pro-inflammatory cytokine expression in Kupffer cells and hepatocytes

Keywords: hepatocytes; Alcohol; Kupffer cells; Hepatocytes; 4-HNE; Cytokines; Chemokines;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Acrolein enhances epigenetic modifications, FasL expression and hepatocyte toxicity induced by anti-HIV drug Zidovudine

Keywords: hepatocytes; AZT; azidothymidine or Zidovudine; ACR; acrolein; ART; antiretroviral therapy; ChIP; chromatin immunoprecipitation; FasL; Fas ligand; H3K9Ac; histone 3 lysine 9 acetylation; H3K4Me3; histone 3 lysine 4 trimethylation; RNA Pol II; RNA polymerase II; TF; tr

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Reduced cardiolipin content decreases respiratory chain capacities and increases ATP synthesis yield in the human HepaRG cells

Keywords: hepatocytes; Cardiolipin synthase; Mitochondrial network; Supercomplexes; Oxidative phosphorylation; Hepatocytes

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Resolvin D1 protects the liver from ischemia/reperfusion injury by enhancing M2 macrophage polarization and efferocytosis

Keywords: hepatocytes; Arginase 1; Arg1; cyclooxygenase; COX; ALX/N-formyl peptide receptor 2; ALX/FPR2; hepatocytes; HPCs; interleukin 1; IL-1; ischemia/reperfusion; IR; Kupffer cell; KC; lipopolysaccharide; LPS; liposome clodronate; LC; lipoxins; Lxs; lipoxygenase; LOX; nucle

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Establishment of a Drug-Induced, Bile Acid-Dependent Hepatotoxicity Model Using HepaRG Cells

Keywords: hepatocytes; hepatocytes; bile acid transporters; biliary excretion; in vitro models; toxicology; cell lines; ALP; alkaline phosphatase; BA; bile acid; BEI; biliary excretion index; BSEP/Bsep; bile salt export pump; CsA; cyclosporine A; DILI; drug-induced liver injur

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Hepatocytes as in vitro test system to investigate metabolite patterns of pesticides in farmed rainbow trout and common carp: Comparison between in vivo and in vitro and across species

Keywords: hepatocytes; FCR; feed conversion ratio; GSI; gonado-somatic index; LSC; liquid scintillation counting; MS; mass spectrometry; MRL; maximum residue level; MeOH; methanol; MXC; methoxychlor; SGR; specific growth rate; TLC; thin-layer chromatography; TRR; total radioact

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

The Role of Extracellular Binding Proteins in the Cellular Uptake of Drugs: Impact on Quantitative In Vitro-to-In Vivo Extrapolations of Toxicity and Efficacy in Physiologically Based Pharmacokinetic-Pharmacodynamic Research

Keywords: hepatocytes; ADME; clearance; disposition; distribution; hepatocytes; IVIVE; partition coefficients; pharmacokinetics; pharmacodynamics; PKPD;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

A bridge to silencing: Co-assembling anionic nanoparticles of siRNA and hyaluronan sulfate via calcium ion bridges

Keywords: hepatocytes; Anionic polymer; Acute phase response; Hepatocytes; Hyaluronan-sulfate; Gene silencing; siRNA delivery; Transfection;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Co-culture of Hepatocytes and Kupffer Cells as an In Vitro Model of Inflammation and Drug-Induced Hepatotoxicity

Keywords: hepatocytes; Kupffer cells; hepatocytes; in vitro model systems; hepatotoxicity; co-culture;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Three nuclear and two membrane estrogen receptors in basal teleosts, Anguilla sp.: Identification, evolutionary history and differential expression regulation

Keywords: hepatocytes; Estrogen nuclear receptor; Estrogen membrane receptor; Teleosts; Evolution; Hepatocytes; Eel

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Hepatocyte Toll-Like Receptor 5 Promotes Bacterial Clearance and Protects Mice Against High-Fat Diet-Induced Liver Disease

Keywords: hepatocytes; Innate Immunity; TLR5; Hepatocytes; Inflammation; Steatosis; ALT; alanine aminotransferase; AST; aspartate aminotransferase; CCL4; carbon tetrachloride; CFU; colony-forming unit; ConA; concanavalin A; CXCL; chemokine (C-X-C motif) ligand 1; DC; dendritic

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2016 سفارش ترجمه

Cyclooxygenase-2 contributes to the selective induction of cell death by the endocannabinoid 2-arachidonoyl glycerol in hepatic stellate cells

Keywords: hepatocytes; Cyclooxygenase-2; 2-Arachidonoyl glycerol; Prostaglandin D2 glycerol ester; Hepatic stellate cells; Hepatocytes; Cell death;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2016 سفارش ترجمه

The dipeptide Pro-Asp promotes IGF-1 secretion and expression in hepatocytes by enhancing JAK2/STAT5 signaling pathway

Keywords: hepatocytes; Dipeptide; Pro-Asp; IGF-1; Hepatocytes; JAK2/STAT5; Akt; protein kinase B; Asp; aspartic acid; ERK; extracellular signal-regulated kinase; GH; growth hormone; IGF-1; insulin-like growth factor 1; JAK2; Janus kinase 2; PepT1; peptide transporter 1; PepT2;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2016 سفارش ترجمه

Modulation of CYP3A4 activity alters the cytotoxicity of lipophilic phycotoxins in human hepatic HepaRG cells

Keywords: hepatocytes; Phycotoxins; Hepatocytes; High content analysis; CYP3A4; Cytotoxicity;

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2016 سفارش ترجمه

Role of PTEN in TNFα induced insulin resistance

Keywords: hepatocytes; Diabetes; Insulin resistance; Hepatocytes; Obesity; Adipocyte; VO-OHpic; 3- hydroxypicolinate vanadium (IV) complex; CDC; Center for Disease Control; MEM; Eagles minimal essential medium; FBG; fasting blood glucose; TG; fasting plasma triglyceride; IR; in

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2015 سفارش ترجمه

Hepatoprotective potential of Saraca ashoka (Roxb.) De Wilde bark by carbon tetrachloride induced liver damage in rats

Keywords: hepatocytes; Hepatotoxicity; Saraca ashoka; Carbon tetrachloride; Hepatocytes

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Nanodiamond-induced increase in ROS and RNS levels activates NF-κB and augments thiol pools in human hepatocytes

Keywords: hepatocytes; Nanodiamonds; Hepatocytes; Oxidative stress; Nitric oxide; NF-κB activation; Thiols

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Cardiotrophin-1 decreases liver apoptosis through calpastatin induction

Keywords: hepatocytes; Cardiotrophin-1; Hepatocytes; Calpastatin; Calpain; Stat3; Akt; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

MicroRNA-122 targets genes related to liver metabolism in chickens

Keywords: hepatocytes; MicroRNA-122; Target genes; Liver metabolism; Chicken; Hepatocytes

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

A non-adhesive hybrid scaffold from gelatin and gum Arabic as packed bed matrix for hepatocyte perfusion culture

Keywords: hepatocytes; Bioreactor; Bioartificial liver; Hepatocytes; Scaffold; Packed bed matrix;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Research ArticleMouse hepatocytes and LSEC proteome reveal novel mechanisms of ischemia/reperfusion damage and protection by A2aR stimulation

Keywords: hepatocytes; HP; hepatocytes; LSEC; liver sinusoidal endothelial cells; A2aR; adenosine 2a receptor; IR; ischemia-reperfusion; CGS21680; 2p-(2-carboxyethyl)-phenyl-amino-50-N-ethylcarboxyamido-adenosine; ROS; reactive oxygen species; 2-DE; two-dimensional gel electrop

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Saturable Hepatic Extraction of Gemcitabine Involves Biphasic Uptake Mediated by Nucleoside Transporters Equilibrative Nucleoside Transporter 1 and 2

Keywords: hepatocytes; transporters; cancer; hepatocytes; equilibrative nucleoside transporter; hepatic transport; kinetics

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Interleukin 6 inhibits HBV entry through NTCP down regulation

Keywords: hepatocytes; HBV; Hepatitis B virus; NTCP; Sodium taurocholate co-transporting polypeptide; IL-6; Interleukin 6; IFN γ; Interferon gamma; ALT; Alanine aminotransferase; TNFα; Tumor Necrosis Factor alpha; IL-1β; Interleukin 1 beta; OSM; Oncostatin M; PHH; Primary Hu

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Research ArticleGene networks and transcription factor motifs defining the differentiation of stem cells into hepatocyte-like cells

Keywords: hepatocytes; FH; Freshly isolated hepatocytes; CS; collagen sandwich; CM; collagen monolayer; SC; stem cells; HLC; hepatocyte-like cells; TF; transcription factors; Stem cells; Hepatocytes; Differentiation; Gene array; Bioinformatics; Transcriptomics; Gene networks;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

New role of irisin in hepatocytes: The protective effect of hepatic steatosis in vitro

Keywords: hepatocytes; Irisin; Hepatic lipogenesis PRMT3; Hepatocytes;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Micron-sized iron oxide-containing particles for microRNA-targeted manipulation and MRI-based tracking of transplanted cells

Keywords: hepatocytes; miRNA; MPIO; MRI; Antisense oligonucleotides; Hepatocytes

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Polarized location of SLC and ABC drug transporters in monolayer-cultured human hepatocytes

Keywords: hepatocytes; Canalicular secretion; Drug transporter; Hepatocytes; Polarization; Primary culture;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Down-regulation of suppressor of cytokine signaling 3 by miR-122 enhances interferon-mediated suppression of hepatitis B virus

Keywords: hepatocytes; MicroRNA-122; Suppressor of cytokine signaling 3; Interferon; Hepatitis B virus; Hepatocytes

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Estrogenic and anti-estrogenic influences in cultured brown trout hepatocytes: Focus on the expression of some estrogen and peroxisomal related genes and linked phenotypic anchors

Keywords: hepatocytes; Ethinylestradiol; ICI 182,780; Peroxisomes; Hepatocytes; Brown trout;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Influence of HIV antiretrovirals on methadone N-demethylation and transport

Keywords: hepatocytes; Methadone; Hepatocytes; Protease inhibitors; Cytochrome P450 3A; CYP3A; Cytochrome P450 2B6; CYP2B6;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Characterization of type I interferon pathway during hepatic differentiation of human pluripotent stem cells and hepatitis C virus infection

Keywords: hepatocytes; Pluripotent stem cells; Endoderm; Hepatocytes; Hepatocyte-like cells; Differentiation; Interferon; Innate immunity; ISG; Interferon-stimulated genes

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Ferritin-stimulated lipid peroxidation, lysosomal leak, and macroautophagy promote lysosomal “metastability” in primary hepatocytes determining in vitro cell survival

Keywords: hepatocytes; ACD; accidental (necrotic) cell death; AO; acridine orange; CM; conditioned medium; DAPI; 4′,6-diamidino-2-phenylindole; DFO; desferrioxamine mesylate; EGF; epidermal growth factor; ELC; endo-/lysosomal compartment; GFL; green AO fluorescence; GSH; glut

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Safety assessment of potential food ingredients in canine hepatocytes

Keywords: hepatocytes; Hepatocytes; In vitro; Toxicity; Food ingredient; PCR array; Dog;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Honokiol activates the LKB1-AMPK signaling pathway and attenuates the lipid accumulation in hepatocytes

Keywords: hepatocytes; ACC; acetyl-CoA carboxylase; AMPK; AMP-activated protein kinase; ATGL; adipose triglyceride lipase; CaMKK; calcium/calmodulin-dependent protein kinase kinase; FAS; fatty acid synthase; FFA; free fatty acid; HFD; high fat diet; Hon; honokiol; LKB1; liver k

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Role of hepatocyte S6K1 in palmitic acid-induced endoplasmic reticulum stress, lipotoxicity, insulin resistance and in oleic acid-induced protection

Keywords: hepatocytes; Lipotoxicity; Insulin signaling; Hepatocytes; Free fatty acids; ER stress; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Synthesis and Evaluation of Bile Acid–Ribavirin Conjugates as Prodrugs to Target the Liver

Keywords: hepatocytes; bile acid transporters; hepatocytes; metabolism; NTCP; prodrugs; ribavirin; site-specific delivery

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Free fatty acids enhance the oxidative damage induced by ethanol metabolism in an in vitro model

Keywords: hepatocytes; Steatosis; Ethanol; Oxidative stress; VL-17A; Hepatocytes;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2015 سفارش ترجمه

Reactivity of autoantibodies against not only erythrocytes but also hepatocytes in sera of mice with malaria

Keywords: hepatocytes; Autoantibody; Plasmodium yoelii; Malaria; Hepatocytes; Erythrocytes;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Decrease of serum S100B during an oral glucose tolerance test correlates inversely with the insulin response

Keywords: hepatocytes; Adipocytes; Astrocytes; Hepatocytes; Insulin; Oligodendrocytes; Oral glucose tolerance; S100B;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Precision-cut liver slices of Atlantic cod (Gadus morhua): An in vitro system for studying the effects of environmental contaminants

Keywords: hepatocytes; Hepatocytes; Liver slices; In vitro; Atlantic cod; CYP1A; VitellogeninPCLS, precision-cut liver slices; AHR, aryl hydrocarbon receptor; ER, estrogen receptor; BNF, β-naphthoflavone; EE2, 17α-ethynylestradiol; CYP, cytochrome P450

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

miRNA-302 facilitates reprogramming of human adult hepatocytes into pancreatic islets-like cells in combination with a chemical defined media

Keywords: hepatocytes; miR-302; Hepatocytes; Pancreatic islets-like cells; Insulin

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Purification, characterisation and protective effects of polysaccharides from alfalfa on hepatocytes

Keywords: hepatocytes; Alfalfa polysaccharides; Monosaccharide analysis; Molecular weight; Hepatocytes; Antioxidant;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Elevated adropin: A candidate diagnostic marker for myocardial infarction in conjunction with troponin-I

Keywords: hepatocytes; Myocardial infarction; Adropin; Cardiac muscle cells; Hepatocytes; Kidneys

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Prolactin is a major inhibitor of hepatic Leptin A synthesis and secretion: Studies utilizing a homologous Leptin A ELISA in the tilapia

Keywords: hepatocytes; Leptin; Prolactin; Pituitary; Hepatocytes; Teleost fishes; Enzyme-linked immunosorbant assay;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Creatine reduces hepatic TG accumulation in hepatocytes by stimulating fatty acid oxidation

Keywords: hepatocytes; ABCA1; ATP binding cassette protein; AMPK; adenosine monophosphate-activated protein kinase; CT; CTP:phosphocholine cytidylyltransferase; DGAT; acyl CoA:diacylglycerol acyltransferase; HDL; high density lipoproteins; HFD; high-fat diet; HCD; high-carbohyd

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه