Selective death of cancer cells by preferential induction of reactive oxygen species in response to (-)-epigallocatechin-3-gallate
Keywords: htert; EGCG; ROS; hTERT; CTCF; DNMT1;
مقالات ISI htert (ترجمه نشده)
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The AAA-ATPase NVL2 is a telomerase component essential for holoenzyme assembly
Keywords: htert; Telomerase; hTERT; NVL2; AAA-ATPase; Nucleolus;
Combined introduction of Bmi-1 and hTERT immortalizes human adipose tissue-derived stromal cells with low risk of transformation
Keywords: htert; Adipose tissue-derived stromal cells; hTERT; Immortalization
Is telomerase a viable target in cancer?
Keywords: htert; ALT; alternative lengthening of telomeres; hTERT; human telomerase reverse transcriptase; hTR; human telomerase RNA; TRAP; telomere repeat amplification protocol; CTL; cytotoxic T lymphocytes; NSCLC; non small cell lung cancer; HLA; human leukocyte antige
Acquisition of mitochondrial dysregulation and resistance to mitochondrial-mediated apoptosis after genotoxic insult in normal human fibroblasts: A possible model for early stage carcinogenesis
Keywords: htert; Cr(VI); hexavalent chromium; TGA; terminal growth arrest; ROS; reactive oxygen species; SMAC/DIABLO; second mitochondria-derived activator of caspases/direct inhibitor of apoptosis binding protein; hTERT; human telomerase; mtDNA; mitochondrial DNA; âÏm
Specific recognition of phosphorylated tail of H2AX by the tandem BRCT domains of MCPH1 revealed by complex structure
Keywords: htert; BRCT; BRCA1 C-terminal domain; IRIF; Ionizing Radiation-Induced Foci; DSBs; double-stranded DNA breaks sites; DDR; DNA damage response; H2AX; histone 2A variant X; hTERT; human telomerase reverse transcriptase; SWI-SNF; switching defective/sucrose non-f
Telomere dysfunction induced by chemotherapeutic agents and radiation in normal human cells
Keywords: htert; β2-M; β2-microglubin; ConA; concanavalin A; DOX; doxorubicin; DSB; double strand DNA break; hTERC; human telomerase RNA component; hTERT; human telomerase reverse transcriptase; IF; immunofluorescence; qRT-PCR; quantitative RT-PCR; TIF; telomere dysfunc
Human telomerase represses ROS-dependent cellular responses to Tumor Necrosis Factor-α without affecting NF-κB activation
Keywords: htert; hTERT; human telomerase reverse transcriptase catalytic subunit; hTR; human telomerase RNA component; ROS; reactive oxygen species; TNF-α; tumor necrosis factor-α; NAC; N-acetyl-L-cysteine; CHX; cycloheximide; ERK1/2; extracellular signal-regulated kina
Androgen receptor-mediated gene repression
Keywords: htert; AR; androgen receptor; AR wt; wild type androgen receptor; ARE; androgen response element; nARE; negative androgen response element; pARE; positive androgen response element; AP-1; activator protein-1; αBE; α basal element; BrCa; breast cancer; CBP; CRE
Recognition, signaling, and repair of DNA double-strand breaks produced by ionizing radiation in mammalian cells: The molecular choreography
Keywords: htert; 53BP1; Tp53 binding protein 1; 9-1-1; RAD9-RAD1-HUS1 checkpoint clamp complex; a.a.; amino acid; ACF1; ATP-utilizing chromatin assembly and remodeling factor 1; ALC1; amplified in liver cancer 1; APLF/PALF; aprataxin and PNKP-like factor; Aprataxi
Circulating DNA is a Useful Prognostic Factor in Patients with Advanced Non-small Cell Lung Cancer
Keywords: htert; hTERT; Telomerase; Plasma; Prognostic factors; Non-small cell lung cancer; NSCLC
Liver-specific gene therapy of hepatocellular carcinoma by targeting human telomerase reverse transcriptase with pegylated immuno-lipopolyplexes
Keywords: htert; hTERT; RNA interference; Hepatocellular carcinoma; Pegylated immuno-lipopolyplexes; Apolipoprotein A-I promoter
Vitamin D and cancer: Deciphering the truth
Keywords: htert; AIF; apoptosis-inducing factor; CDK; cyclin-dependent kinase; COX-2; cyclo-oxygenase 2; E2F1; E2F transcription factor 1; HIF1a; hypoxia inducible factor 1 alpha; hTERT; human telomerase reverse transcriptase; IL-8; interleukin-8; NFkB; nuclear factor kap
A new human dyskerin isoform with cytoplasmic localization
Keywords: htert; DC; Dyskeratosis Congenita; X-DC; X-linked Dyskeratosis Congenita; snoRNA; small nucleolar RNA; snoRNPs; small nucleolar RNA ribonucleoproteins; hTERT; human telomerase reverse transcriptase; hTR; human telomerase RNA component; IRES; Internal Ribosome En
RuvBl2 cooperates with Ets2 to transcriptionally regulate hTERT in colon cancer
Keywords: htert; RuvBl2; hTERT; c-Myc; Colon cancer;
NF-kappaB p65 modulates the telomerase reverse transcriptase in the HepG2 hepatoma cell line
Keywords: htert; Hepatocellular carcinoma; NF-kappaB; hTERT; Dexamethasone; MG-132; LPS
Construction, modification and evaluation of apolipoprotein A-I promoter-driven shRNA expression vectors against hTERT
Keywords: htert; shRNA; RNA polymerase II; RNA polymerase III; Apolipoprotein A-I; hTERT;
Sphingolipids and expression regulation of genes in cancer
Keywords: htert; C1P; ceramide 1-phosphate; CAPP; ceramide-activated protein phosphatase; CerK; ceramide kinase; CerS; ceramide synthase; CERT; ceramide transfer protein; COX-2; cyclooxygenase-2; CPPase; ceramide phosphate phosphatase; CSC; cancer stem cell; ES; embryo st
Immortalization and functional characterization of rat arachnoid cell lines
Keywords: htert; membrane transport; CSF; retroviral vector; SV40 LTAg; hTERT; CSF; cerebrospinal fluid; DT; double-transduced; FBS; fetal bovine serum; hTERT; human telomerase; LTAg; large T antigen; PBS; phosphate buffered saline; rTERT; rat telomerase; SEM; scanning el
The Promoter of Human Telomerase Reverse Transcriptase Is Activated During Liver Regeneration and Hepatocyte Proliferation
Keywords: htert; Liver Disease; Telomere; Chromosome; Hepatitis; cDNA; complementary DNA; ChiP; chromatin immunoprecipitation; hTERT; human TERT; mRNA; messenger RNA; PCR; polymerase chain reaction; PH; partial hepatectomy; TERT; telomerase reverse transcriptase; shRNA; s
Acycloguanosyl 5â²-thymidyltriphosphate, a Thymidine Analogue Prodrug Activated by Telomerase, Reduces Pancreatic Tumor Growth in Mice
Keywords: htert; Suicide Gene Therapy; Human Telomerase Reverse Transcriptase; hTERT; Telomere; ACV; acyclovir; ACV-TP-dA; acycloguanosyl 2â²-deoxy-5â²-adenosyltriphosphate; ACV-TP-dC; acycloguanosyl 5â²-cythydyltriphosphate; ACV-TP-dG; acycloguanosyl 2â²-deoxy-5â²-g
Leptin upregulates telomerase activity and transcription of human telomerase reverse transcriptase in MCF-7 breast cancer cells
Keywords: htert; Leptin; Telomerase; hTERT; STAT3;
Human telomerase reverse transcriptase expression in colorectal tumors: correlations with immunohistochemical expressionand clinicopathologic features
Keywords: htert; hTERT; Immunohistochemistry; Colorectal tumors; Clinicopathologic features;
Flow cytometric detection of human telomerase reverse transcriptase (hTERT) expression in a subpopulation of bone marrow cells
Keywords: htert; Telomerase; hTERT; Hematopoietic cell; Flow cytometry
Rapamycin inhibits cell proliferation in type I and type II endometrial carcinomas: A search for biomarkers of sensitivity to treatment
Keywords: htert; Rapamycin; PTEN; Akt; hTERT; Endometrial carcinoma; mTOR pathway
Cell turnover in apocrine metaplasia and apocrine adenosis of the breast
Keywords: htert; TUNEL; Breast; Apocrine; Apoptosis; Proliferation; hTERT
Human chromosome 5 carries a transcriptional regulator of human telomerase reverse transcriptase (hTERT)
Keywords: htert; Telomerase; Repressor; Chromosome transfer; Human chromosome 5; hTERT
Telomerase in cancer immunotherapy
Keywords: htert; Tumor-associated antigen; Telomerase; hTERT; T cell; Cancer immunotherapy
Tumor cell redox state and mitochondria at the center of the non-canonical activity of telomerase reverse transcriptase
Keywords: htert; hTERT; Mitochondria; ROS; Apoptosis; Senescence
Identification of small molecule inhibitors of telomerase activity through transcriptional regulation of hTERT and calcium induction pathway in human lung adenocarcinoma A549 cells
Keywords: htert; Small molecule; Telomerase activity; hTERT; hTERT promoter; Anchorage-independent growth; Calcium release
Immunogenicity of a recombinant lentiviral vector carrying human telomerase tumor antigen in HLA-B*0702 transgenic mice
Keywords: htert; Lentiviral vector; hTERT; CD8 T cells
Liver cancer: From molecular pathogenesis to new therapies
Keywords: htert; DEB; drug-eluting bead; HBV; hepatitis B virus; HCC; hepatocellular carcinoma; HCV; hepatitis C virus; hTERT; human telomerase reverse transcriptase; PDGF; platelet derived growth factor; FAK; focal adhesion kinase; Pyk2; proline-rich tyrosine kinase 2; M
Knockdown of hTERT and concurrent treatment with interferon-gamma inhibited proliferation and invasion of human glioblastoma cell lines
Keywords: htert; Cell invasion; Glioblastoma; hTERT; IFN-γ; Telomerase
Immortalized Epithelial Cells Derived From Human Colon Biopsies Express Stem Cell Markers and Differentiate In Vitro
Keywords: htert; Stem/Progenitor Cells; Epithelial Mesenchymal Transition; Self-Renewal; Multilineage Differentiation; BIO; bromoindirubin-3-oxime; 2D; two-dimensional; 3D; three-dimensional; Cdk4; cyclin-dependent kinase-4; EGF; epithelial growth factor; GSK-3β; glycoge
Telomerase and DNA repair in glioma
Keywords: htert; Glioma; hTERT; MGMT; Chemotherapy;
Telomerase reverse transcriptase activates the expression of vascular endothelial growth factor independent of telomerase activity
Keywords: htert; Telomerase; hTERT; VEGF;
Immortalization of ameloblastoma cells via reactivation of telomerase function: Phenotypic and molecular characteristics
Keywords: htert; Ameloblastoma; Telomerase; hTERT; Immortalization; Transfection
The detection of circulating tumor cells of breast cancer patients by using multimarker (Survivin, hTERT and hMAM) quantitative real-time PCR
Keywords: htert; Breast cancer; Circulating tumor cells; Quantitative real-time PCR; Survivin; hTERT; hMAM
Novel semisynthetic triterpenoid AMR-Me inhibits telomerase activity in human leukemic CEM cells and exhibits in vivo antitumor activity against Dalton’s lymphoma ascites tumor
Keywords: htert; AMR-Me; Leukemia; Telomerase; hTERT; Apoptosis; Dalton’s lymphoma ascites tumor
Butein suppresses c-Myc-dependent transcription and Akt-dependent phosphorylation of hTERT in human leukemia cells
Keywords: htert; Butein; Telomerase; hTERT; c-Myc; Akt
An immortalized goat mammary epithelial cell line induced with human telomerase reverse transcriptase (hTERT) gene transfer
Keywords: htert; Immortalization; Goat mammary epithelial cells; hTERT; Somatic cell nuclear transfer; Donor cells
Telomerase, mitochondria and oxidative stress
Keywords: htert; Telomerase; Oxidative stress; Telomere-independent function; hTERT; Mitochondria
Molecular and phenotypic modulations of primary and immortalized canine chondrocytes in different culture systems
Keywords: htert; Canine chondrocytes; Alginate culture; Phenotype; Immortalization; hTERT
The Isolation and Characterization of a Novel Telomerase Immortalized First Trimester Trophoblast Cell Line, Swan 71
Keywords: htert; Apoptosis; hTERT; Placenta; Pregnancy; Telomerase; Trophoblast
Arsenic induces telomerase expression and maintains telomere length in human cord blood cells
Keywords: htert; In vitro; Arsenic; hTERT; ROS; BSO; DMPO
Papillomavirus E6 proteins
Keywords: htert; HPV; E6 oncogene; p53; Apoptosis; hTERT
Differential hTERT mRNA processing between young and older glioma patients
Keywords: htert; hTERT; Telomerase; Telomere length; Age; Glioma
Telomerase-mediated life-span extension of human primary fibroblasts by human artificial chromosome (HAC) vector
Keywords: htert; Human artificial chromosome (HAC); Non-integrating vector; Telomerase; hTERT; Life-span extension; Cellular proliferation; Primary cultured cells
Melatonin down-regulates hTERT expression induced by either natural estrogens (17β-estradiol) or metalloestrogens (cadmium) in MCF-7 human breast cancer cells
Keywords: htert; hTERT; Estradiol; Cadmium; Melatonin; MCF-7 cells
Identification and functional characterization of novel telomerase variant alleles in Japanese patients with bone-marrow failure syndromes
Keywords: htert; Telomeres; Telomerase; Aplastic anemia; Myelodysplastic syndromes; Bone-marrow failure syndromes; hTERC; hTER; hTR; hTERT