Keywords: عامل القایی هیپوکسی 1α; Anoxia; Hypoxia inducible factor-1α; Reactive oxygen species; Anaerobic; Cell cycle; Phenotypic variation;
مقالات ISI عامل القایی هیپوکسی 1α (ترجمه نشده)
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Keywords: عامل القایی هیپوکسی 1α; ARDS; Acute respiratory distress syndrome; TRALI; Transfusion-related acute lung injury; IPF; Idiopathic pulmonary fibrosis; CF; Cystic fibrosis; COPD; Chronic obstructive pulmonary disease; PAP; Pulmonary alveolar proteinosis BAL Bronchoalveolar lavage;
Keywords: عامل القایی هیپوکسی 1α; FFAs; free fatty acids; HFD; high-fat diet; HIF-1α; hypoxia inducible factor-1α; VEGF; vascular endothelial growth factor; Glut1; glucose transporter 1; DAG; diacylglycerol; PKCθ; protein kinase Cθ; PDE3B; phosphodiesterase 3B; cAMP; cyclic AMP; Metfo
Keywords: عامل القایی هیپوکسی 1α; AMPK; AMP-activated protein kinase; BM; bone marrow; CAT; catalase; Complex I; NADH-coenzyme Q oxidoreductase; Complex II; succinate-coenzyme Q oxidoreductase; Complex III; ubiquinol-cytochrome c oxidoreductase; COX; cytochrome c oxidase; Complex V; FoF1A
Keywords: عامل القایی هیپوکسی 1α; Nickel; Mitochondria; Fatty acid oxidation; Lung fibroblast; Hypoxia inducible factor-1α; Very long-chain acyl-CoA dehydrogenase;
Keywords: عامل القایی هیپوکسی 1α; 3D; three dimensional; DIV; days in vitro; DMEM; Dulbecco's modified Eagle's medium; ECM; extracellular matrix; FBS; fetal bovine serum; HBSS; Hanks' balanced salt solution; HIF-1α; hypoxia inducible factor-1α; HS; horse serum; PBS; phosphate buff
Keywords: عامل القایی هیپوکسی 1α; Asthma; COPD; DNA methylation; Fibrosis; Histone code; Noncoding RNA; ACD/MPV; alveolar capillary dysplasia and misalignment of pulmonary veins; BMPR2; bone morphogenetic protein receptor 2; COPD; chronic obstructive pulmonary disease; COX-2; cyclooxygena
Keywords: عامل القایی هیپوکسی 1α; AdVEGF; adenoviral vector encoding vascular endothelial growth factor; aFGF; acidic fibroblast growth factor; Ang-1; angiopoietin 1; bFGF; basic fibroblast growth factor; BMDCs; bone marrow-derived cells; BVR; biliverdin reductase; Del-1; developmental en
SIRT3-mediated cardiac remodeling/repair following myocardial infarction
Keywords: عامل القایی هیپوکسی 1α; MI; myocardial infarction; HIF; hypoxia inducible factor-1α; SOD2; superoxide dismutase; FOXO3A; forkhead box O3a; OPA1; optic atrophy 1; MMPs; matrix metalloproteinases; TGF-β; transforming growth factor-β; PARP-1; poly (ADP ribose)- polymerase 1; VEG
Endogenous acetylcholine regulates neuronal and astrocytic vascular endothelial growth factor expression levels via different acetylcholine receptor mechanisms
Keywords: عامل القایی هیپوکسی 1α; Vascular endothelial growth factor; Endogenous acetylcholine; Acetylcholine receptor; Medial septal cholinergic neurons; ACh; acetylcholine; AChE; acetylcholinesterase; AChR; acetylcholine receptor; AraC; cytosine β-d-arabinofuranoside hydrochloride; CCh
GLA supplementation regulates PHD2 mediated hypoxia and mitochondrial apoptosis in DMBA induced mammary gland carcinoma
Keywords: عامل القایی هیپوکسی 1α; AA; arachidonic acid; AB; alveolar bud; AAA; aromatic amino acid; BCAA; branched chain amino acid; BSA; bovine serum albumin; BMRB; biological magnetic resonance databank; CEC; cuboidal epithelial cell; CPMG; carr-purcell-meiboom-gill; DMBA; 7, 12-d
Genistein rescues hypoxia-induced pulmonary arterial hypertension through estrogen receptor and β-adrenoceptor signaling
Keywords: عامل القایی هیپوکسی 1α; α-SMA; α-smooth muscle actin; CAT; catalase; CCK-8; cell counting kit-8; ER; estrogen receptor; FSC; forward cell scatter; Fura 2 AM; fura 2 acetoxymethy ester; HIF-1α; hypoxia inducible factor-1α; IL-1β; interleukin-1β; MLC; myosin light chain; MLC
Jianpi Jiedu decoction, a traditional Chinese medicine formula, inhibits tumorigenesis, metastasis, and angiogenesis through the mTOR/HIF-1α/VEGF pathway
Keywords: عامل القایی هیپوکسی 1α; JPJD; Jianpi Jiedu decoction; CRC; colorectal cancer; TUNEL; Terminal deoxynucleotidyl transferase dUTP nick end labeling; IHC; immunohistochemistry; MTT; 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide; mTOR; mammalian target of rapamyc
β-N-oxalyl-L-α,β-diaminopropionic acid induces wound healing by stabilizing HIF-1α and modulating associated protein expression
Keywords: عامل القایی هیپوکسی 1α; L-ODAP; Lathyrus sativus; Wound healing; Hypoxia inducible factor-1α; DAB; 3,3â²-diaminobenzidine (DAB); DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethyl sulphoxide; ECM; extracellular matrix; HIF; hypoxia-inducible factor; HRE; hypoxia response
Expression of hypoxia inducible factor-1α and its correlation with phosphoenolpyruvate carboxykinase after portal vein ligation in rats
Keywords: عامل القایی هیپوکسی 1α; Portal vein ligation; Liver regeneration; Hypoxia inducible factor-1α; Phosphoenolpyruvate carboxykinase;
The metabolic bone disease associated with the Hyp mutation is independent of osteoblastic HIF1α expression
Keywords: عامل القایی هیپوکسی 1α; FGF23; Phosphate; Hypoxia inducible factor-1α; X-linked hypophosphatemia;
Roles of hypoxia inducible factor-1α in the temporomandibular joint
Keywords: عامل القایی هیپوکسی 1α; Temporomandibular joint osteoarthritis (TMJ-OA); Hypoxia inducible factor-1α; Articular cartilage degradation; Chondrocyte apoptosis;
The pivotal role of HIF-1α in lung inflammatory injury induced by septic mesenteric lymph
Keywords: عامل القایی هیپوکسی 1α; Sepsis; Hypoxia inducible factor-1α; Acute lung injury; Inflammation; A549; HPMEC;
Protective role of hypoxia-inducible factor-1α-dependent CD39 and CD73 in fulminant acute liver failure
Keywords: عامل القایی هیپوکسی 1α; ALF; acute liver failure; HIF-1α; hypoxia inducible factor-1α; CD39; ecto-5â²-nucleotidase 39; CD73; ecto-5â²-nucleotidase 73; Acute liver failure; CD39; CD73; HIF-1α;
Role of HIF-1α signaling pathway in osteoarthritis: a systematic review
Keywords: عامل القایی هیپوکسی 1α; Hypoxia inducible factor-1α; HIF-1α signaling pathway; Genetic polymorphisms; Osteoarthritis; Fator induzÃvel por hipóxia 1-α; Via de sinalização do HIF-1α; Polimorfismos genéticos; Osteoartrite;
HIF-1α/Ascl2/miR-200b regulatory feedback circuit modulated the epithelial-mesenchymal transition (EMT) in colorectal cancer cells
Keywords: عامل القایی هیپوکسی 1α; ChIP; chromatin immunoprecipitation; CRC; colorectal cancer; PCR; polymerase chain reaction; RT; reverse transcription; EMT; epithelial-mesenchymal transition; MET; mesenchymal-epithelial transition; Ascl2; Achaete scute-like 2; HIF-1α; hypoxia inducible
The Vascular Endothelial Growth Factor-A phosphorylates Murine Double Minute-2 on its Serine 166 via the Extracellular Signal-Regulated Kinase 1/2 and p90 Ribosomal S6 Kinase in primary human endothelial cells
Keywords: عامل القایی هیپوکسی 1α; Angiogenesis; Endothelial cell; Skeletal muscle; ERK1/2; extracellular signal-regulated kinase 1/2; HIF-1α; hypoxia inducible factor-1α; HDMECs; human dermal microvascular endothelial cells; MAPK; mitogen activated protein kinases; Mdm2; murine double m
Isoflurane neurotoxicity involves activation of hypoxia inducible factor-1α via intracellular calcium in neonatal rodents
Keywords: عامل القایی هیپوکسی 1α; Isoflurane; Hypoxia inducible factor-1α; Neurotoxicity; Calcium;
CD271 Down-Regulation Promotes Melanoma Progression and Invasion in Three-Dimensional Models and in Zebrafish
Keywords: عامل القایی هیپوکسی 1α; 3D; three-dimensional; HIF-1α; hypoxia inducible factor-1α; MIC; melanoma-initiating cell; MM; metastatic melanoma; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; PM; primary melanoma;
Lack of mitochondrial DNA impairs chemical hypoxia-induced autophagy in liver tumor cells through ROS-AMPK-ULK1 signaling dysregulation independently of HIF-1α
Keywords: عامل القایی هیپوکسی 1α; Akt; protein kinase B; AMPK; AMP-activated protein kinase; AVOs; acidic vesicular organelles; BNIP3; BCL2/adenovirus E1B 19Â kDa interacting protein 3; BNIP3L; BCL2/adenovirus E1B 19Â kDa interacting protein 3-like; CCND1; cyclin D1; CFSE; 5-(6)-carboxyfl
Redox cycling metals: Pedaling their roles in metabolism and their use in the development of novel therapeutics
Keywords: عامل القایی هیپوکسی 1α; AC; adenylyl cyclase; AI; anemia of inflammation; cdks; cyclin-dependent kinases; bFGF; basic fibroblast growth factor; BpT; 2-benzoylpyridine thiosemicarbazone; Bp4eT; 2-benzoylpyridine 4-ethyl-3-thiosemicarbazone; Bp44mT; 2-benzoylpyridine 4,4-dimethyl-
hCG stimulates angiogenic signals in lymphatic endothelial and circulating angiogenic cells
Keywords: عامل القایی هیپوکسی 1α; hCG; human chorionic gonadotropin; HIF-1α; hypoxia inducible factor-1α; CXCL12; C-X-C motif chemokine 12; CXCR4; C-X-C chemokine receptor type 4; CAC; circulating angiogenic cells; LH; luteinizing hormone; LEC; lymphatic endothelial cells; UTM; uterine
Analysis of Hypoxia-Inducible Factor-1α Expression Relative to Other Key Factors in Malignant Canine Mammary Tumours
Keywords: عامل القایی هیپوکسی 1α; dog; hypoxia inducible factor-1α; immunohistochemistry; mammary tumours;
Punicalagin improves chorioallantoic and yolk sac vasculogenesis and teratogenesis of embryos induced by nicotine exposure
Keywords: عامل القایی هیپوکسی 1α; Punicalagin; Nicotine; Teratogenesis; Placenta; Yolk sac; Vascularization; ROS; reactive oxygen species; TBARS; thiobarbituric acid reactive substances; MDA; malondialdehyde; SOD1; cytoplasmic superoxide dismutase; GPx1; cytoplasmic glutathione peroxidase
δ-Tocotrienol treatment is more effective against hypoxic tumor cells than normoxic cells: potential implications for cancer therapy
Keywords: عامل القایی هیپوکسی 1α; Akt; protein kinase B; CDK4; cyclin-dependent kinase 4; DLD-1; human colorectal adenocarcinoma cell line; H&E; hematoxylin and eosin; HIF-1α; hypoxia inducible factor-1α; NIH; National Institutes of Health; PBS; phosphate-buffered saline; PECAM-1; plate
OKN-007 decreases free radical levels in a preclinical F98 rat glioma model
Keywords: عامل القایی هیپوکسی 1α; BSA; bovine serum albumin; CNS; central nervous system; ERK 1/2; extracellular signal-regulated kinase 1/2; DMPO; 5,5-dimethyl-1-pyrroline N-oxide; DTPA; diethylene triamine penta acetic acid; EGF; epidermal growth factor; Gd; gadolinium; HIF-1α; hypoxia
Tanshinone IIA dampens the cell proliferation induced by ischemic insult in rat astrocytes via blocking the activation of HIF-1α/SDF-1 signaling
Keywords: عامل القایی هیپوکسی 1α; Astrocytes; Ischemia; Tanshinone IIA; Hypoxia inducible factor-1α; Stromal cell-derived factor-1;
Cloning, characterization, hypoxia and heat shock response of hypoxia inducible factor-1 (HIF-1) from the small abalone Haliotis diversicolor
Keywords: عامل القایی هیپوکسی 1α; HIF-1α; hypoxia inducible factor-1α; HIF-1β; hypoxia inducible factor-1β; ARNT; aryl hydrocarbon receptor nuclear translocator; bHLH/PAS; basic helix-loop-helix/Per-Arnt-Sim; CBP; CREB1-binding protein; C-TAD; C-terminal transactivation domain; DO
Research ReportEvidence that neuronal Notch-1 promotes JNK/c-Jun activation and cell death following ischemic stress
Keywords: عامل القایی هیپوکسی 1α; ATF2; activating transcription factor 2; DAPT; N-[N-(3,5-Difluorophenacetyl)-l-alanyl]-S-phenylglycine t-butyl ester; CE; compound E; GD; glucose-deprived; HIF-1α; hypoxia inducible factor-1α; JNK; c-Jun N-terminal kinases; MAPK; mitogen-activated prote
NR4A nuclear receptors are orphans but not lonesome
Keywords: عامل القایی هیپوکسی 1α; 6-MP; 6-mercaptopurine; 9-cis-RA; 9-cis-retinoic acid; AMP; adenosine monophosphate; AMPK; AMP-activated protein kinase; Cam-kinase; calcium/calmodulin-dependent protein kinase; CREB; cAMP response element binding protein; DBD; DNA-binding domain; DSB; DN
Molecular functions of the iron-regulated metastasis suppressor, NDRG1, and its potential as a molecular target for cancer therapy
Keywords: عامل القایی هیپوکسی 1α; Akt; protein kinase B; CPT-11; irinotecan; CMT4D; Charcot-Marie-Tooth disease, type 4D; DFO; deferoxamine (or desferrioxamine B); DpC; di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone; DpT; di-2-pyridylketone thiosemicarbazone; Dp44mT; di-
Menadione and ethacrynic acid inhibit the hypoxia-inducible factor (HIF) pathway by disrupting HIF-1α interaction with p300
Keywords: عامل القایی هیپوکسی 1α; Hypoxia inducible factor-1α; p300; Small molecule inhibitor; Menadione; Ethacrynic acid;
Role of hypoxia inducible factor-1α in remote limb ischemic preconditioning
Keywords: عامل القایی هیپوکسی 1α; RIPC; remote ischemic preconditioning; I/R; ischemia/reperfusion; HIF-1α; hypoxia inducible factor-1α; HIF1a; gene encoding the HIF-1α protein; MI; myocardial infarction; Cd; cadmium; IS; infarct size; IPC; local ischemic preconditioning; PCR; polymera
Dehydration mediated microRNA response in the African clawed frog Xenopus laevis
Keywords: عامل القایی هیپوکسی 1α; AMPK; Adenosine monophosphate-activated protein kinase; ERK; Extracellular signal-regulated kinases; HIF-1α; Hypoxia inducible factor-1α; JNK; C-Jun N-terminal kinases; KEGG; Kyoto encyclopedia of Genes and Genomes; MAPK; Mitogen activated protein kinas
The SLC16 gene family - Structure, role and regulation in health and disease
Keywords: عامل القایی هیپوکسی 1α; CHC; α-cyano-4-hydroxycinnamate; DIDS; 4,4â²-di-isothiocyanostilbene-2,2â²-disulphonate; HIF-1α; hypoxia inducible factor-1α; MCT; monocarboxylate transporter; pCMBS; p-chloromercuribenzenesulphonate; PSD; postsynaptic density; TM; transmembrane heli
The accumulations of HIF-1α and HIF-2α by JNK and ERK are involved in biphasic effects induced by different levels of arsenite in human bronchial epithelial cells
Keywords: عامل القایی هیپوکسی 1α; Biphasic effects; Hypoxia inducible factor-1α; Hypoxia inducible factor-2α; Extracellular signal-regulated kinases (ERK); c-Jun N-terminal kinases (JNK); Arsenite;
ATF3 inhibits adipocyte differentiation of 3T3-L1 cells
Keywords: عامل القایی هیپوکسی 1α; ATF3; activation transcription factor 3; ATF/CRE; ATF/CREB responsive element; C/EBP; CCAAT/enhancer-binding proteins; ChIP; chromatin immunoprecipitation; EMSA; electrophoretic mobility shift assay; aP2; adipocyte fatty acid binding protein; HIF-1α; hyp
Metabolic reprogramming in cancer: Unraveling the role of glutamine in tumorigenesis
Keywords: عامل القایی هیپوکسی 1α; Gls; glutaminase; GDH; glutamate dehydrogenase; PC; pyruvate carboxylase; GFAT; fructose-6-phosphate amido-transferase; GSH; glutathione; GlcNAc; N-acetyl-d-glucosamine; PRPP; 5-phospho-α-d-ribosyl 1-pyrophosphate; AOA; aminooxyacetate; EAA; essential am
Effect of trifluoperazine on toxicity, HIF-1α induction and hepatocyte regeneration in acetaminophen toxicity in mice
Keywords: عامل القایی هیپوکسی 1α; APAP; acetaminophen; ALT; alanine aminotransferase; cPLA2; cytosolic phospholipase A2; (CYC); cyclosporine A; GSH; glutathione; HIF-1α; hypoxia inducible factor-1α; MPT; mitochondrial permeability transition; PCNA; proliferating cell nuclear antigen; PG
Mechanism of TNF-α autocrine effects in hypoxic cardiomyocytes: Initiated by hypoxia inducible factor 1α, presented by exosomes
Keywords: عامل القایی هیپوکسی 1α; Hypoxia; Cardiomyocytes; Tumor necrosis factor-α; Hypoxia inducible factor-1α; Exosomes;
Retinoic acid increases hypoxia-inducible factor-1α through intracrine prostaglandin E2 signaling in human renal proximal tubular cells HK-2
Keywords: عامل القایی هیپوکسی 1α; Hypoxia inducible factor-1α; All trans retinoic acid; Cyclooxigenases; Prostaglandin E2; Human proximal tubular cells;
Cyanide preconditioning protects brain endothelial and NT2 neuron-like cells against glucotoxicity: Role of mitochondrial reactive oxygen species and HIF-1α
Keywords: عامل القایی هیپوکسی 1α; Cyanide; Glucotoxicity; Hypoxia inducible factor-1α; Mitochondria; Mitochondrial network; Preconditioning; Mitochondrial reactive oxygen species;
The transferrin receptor and the targeted delivery of therapeutic agents against cancer
Keywords: عامل القایی هیپوکسی 1α; AD; adamantane; ADEPT; antibody-directed enzyme prodrug therapy; ADR; doxorubicin/adriamycin; Av; avidin; AVET; adenovirus-enhanced transferrinfection; ART; artemisinin; BAP; biotin-adaptor peptide; BBB; blood-brain barrier; BFU-E; blast forming unit-er
Role of HIF-1α in maternal hyperglycemia-induced embryonic vasculopathy
Keywords: عامل القایی هیپوکسی 1α; constitutively active hypoxia inducible factor-1α; diabetic embryonic vasculopathy; hypoxia inducible factor-1α; maternal diabetes; vascular endothelial growth factor;
Effect of pioglitazone on diabetic nephropathy and expression of HIF-1α and VEGF in the renal tissues of type 2 diabetic rats
Keywords: عامل القایی هیپوکسی 1α; Pioglitazone; Diabetes; Hypoxia inducible factor-1α; Vascular endothelial growth factor; Nephropathy;