Keywords: Amyloid aggregation; IAPP; αS; Protein corona; Membrane; Inhibition;
مقالات ISI (ترجمه نشده)
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Keywords: Aβ1-42; 42-amino acid-long Aβ peptide; AD; Alzheimer's disease; ADAPT; Alzheimer's Disease Anti-Inflammatory Prevention Trial; ADAS-Cog; Alzheimer's Disease Assessment Scale-Cognitive Subscale; ADCS-ADL; Alzheimer's Disease Cooperative Study Activ
Keywords: IAPP; islet amyloid polypeptide; ESI-IMS-MS; Electrospray Ionization Ion Mobility Spectrometry Mass Spectrometry; Amylin; Insulin; LisPro; Aspart; Pramlintide; Diabetes;
Keywords: Membrane; Amyloid; Helical; α-Synuclein; IAPP; Aggregation;
Keywords: IAPP; Obesity; Amyloid beta; Diabetes; CGRP; Pramlintide;
Keywords: Aβ; amyloid beta; AD; Alzheimer's disease; BBB; blood brain barrier; CCB; calcium channel blocker; Chol; cholesterol; Cys; cysteine; DHPC; 1,2-dihexanoyl-sn-glycero-3-phosphocholine; DLPC; 1,2-dilauroyl-sn-glycero-3-phosphocholine; DMPC; 1,2-dimyristoyls
Keywords: Aβ; amyloid-beta; AFM; atomic force microscopy; ANS; 8-anilino-1-naphthalenesulfonate; αSNWT; wild-type α-synuclein; αSN103; C-terminally truncated α-synuclein; CD; circular dichroism; CTR; C-terminal region; DHPC; 1,2-dihexanoyl-sn-glycero-3-phospho
Keywords: T1D; type 1 diabetes; T2D; type 2 diabetes; IAPP; islet amyloid polypeptide; C4BP; C4b binding protein; MAC; membrane attack complex; ASC; apoptosis-associated speck like protein containing a CARD domain; Complement; Diabetes; CD59; C4BP; Insulin secretio
Keywords: Obesity; IAPP; Reward; Mesolimbic; Macronutrient; Diet;
Keywords: AD; Alzheimer disease; TEM; transmission electron microscopy; ThS; thioflavin S; PI; propidium iodide; DAPI; 4â²,6â²-diamino-2-phenylindole dihydrochloride; IAPP; islet amyloid polypeptide; TDP-43; TAR DNA-binding protein of 43Â kDa; MTT; 3-(4,5-dimethy
Keywords: Calcitonin; Food intake; IAPP; Motivated behavior; Obesity; Reward;
Keywords: IAPP; islet amyloid polypeptide; hIAPP; human IAPP; DEPC; diethylpyrocarbonate; DMI; DEPC-modified hIAPP; HFIP; 1,1,1,3,3,3-hexafluoro-2-propanol; ThT; thioflavin-T; Modification; Amyloid; hIAPP; Imidazole ring;
Keywords: DKD; diabetic kidney disease; ATR-FTIR; attenuated total reflectance-Fourier transform infrared; ANN; artificial neural network; HCA; hierarchical cluster analysis; PCA; principal component analysis; ESRD; end-stage renal disease; AGEs; advanced glycation
Keywords: IAPP; Obesity; Pramlintide; Alzheimer's; Leptin; Motivation
Keywords: IAPP; islet amyloid polypeptide; ESI-IMS-MS; electrospray ionization-ion mobility spectrometry-mass spectrometry; Amylin; Islet amyloid polypeptide; Zinc; Amyloid; Diabetes; Oligomer; Islet;
Keywords: AGEs; advanced glycation end products; ATM; Adipose tissue macrophage; CCL; chemokine (C-C motif) ligand; CCR2; chemokine (C-C motif) receptor 2; CX3CL1; chemokine (C-X3-C motif) ligand 1; CX3CR1; chemokine (C-X3-C motif) receptor 1; CXCL; CXC chemokine l
Keywords: GLUT; Glucose transporter; T1DM; Type-1 diabetes mellitus; T2DM; Type-2 diabetes mellitus; PKB/Akt; protein kinase B; GSK-3; glycogen synthase kinase-3; PGC-1α; peroxisome proliferator-activated receptor gamma coactivator-1α; FOXO; forkhead box O; VLDL;
Keywords: Thermogenic program; Obesity; Dual browning gene construct; IAPP; FNDC5; Irisin
Keywords: Variable domain of heavy-chain antibody; Inhibition of protein misfolding and aggregation; Protein misfolding diseases; Amyloidoses; VHH; Nanobody; Ab; antibody; Aβ; amyloid β-peptide; AD; Alzheimer's disease; ANS; anilino naphthalene-sulfonic acid; AP;
Keywords: ECC; eccentric; CON; concentric; GH; growth hormone; IGF-I; insulin-like-growth-factor I; LVH; left ventricular hypertrophy; 1-RM; one-repetition maximum; P13K-Akt/mTOR; phosphatidylinositol 3-kinase-protein kinase B-mammalian target of rapamycin; IAPP; i
Keywords: ACTB; actin, beta; ACOX1; acyl-CoA oxidase 1; ADCYAP1R1; adenylate cyclase activating polypeptide 1 receptor 1; ADIPOQ; adiponectin C1Q and collagen domain containing; ADIPOR1; adiponectin receptor 1; ADIPOR2; adiponectin receptor 2; ADRA2B; adrenergic re
Keywords: Pattern recognition receptor; obesity; microbiota; metabolic inflammation; ACS; Apoptosis-associated speck-like protein containing a CARD; BM; Bone marrow; DAMP; Danger-associated molecular pattern; HFD; High-fat diet; IAPP; Islet amyloid polypeptide; IKK
Keywords: AD; Alzheimer's disease; ANS; 1-anilinonaphthalene-8-sulfonic acid; AS; α-synuclein; CMC; critical micellar concentration; CTE; chronic traumatic encephalopathy; EPR; electron paramagnetic; ETeff; energy transfer efficiency; FRET; Förster resonance en
Keywords: IAPP; islet amyloid polypeptide; ESI-IMS-MS; Electrospray Ionization-Ion Mobility Spectrometry-Mass Spectrometry; Amylin; Islet associated polypeptide; IAPP; Amyloid; Diabetes;
Keywords: Islet amyloid polypeptide; Amylin; Amyloid; Type 2 diabetes; IAPP;
Keywords: Amylin; IAPP; MSH; Pituitary; Axolotl; Amphibian
Aggregation of the diabetes-related peptide ProIAPP1-48 measured by dynamic light scattering
Keywords: IAPP; ProIAPP; Amylin; Amyloid: aggregation; Copper in biology; Aluminium in biology; Dynamic light scattering;
Selectivity of the phospholamban ion channel investigated by single channel measurements
Keywords: PLN; phospholamban; SERCA; Ca-ATPase; SR; sarcoplasmic reticulum; BLMs; bilayer lipid membranes; GUVs; giant unilamellar vesicles; tBLMs; tethered bilayer lipid membranes; DPhPC; diphytanoylphosphatidylcholine; Iapp; apparent single channel current amplit
Levels of retinal IAPP are altered in Alzheimer's disease patients and correlate with vascular changes and hippocampal IAPP levels
Keywords: Alzheimer's disease; Hippocampus; IAPP; Pericytes; Retina;
A role for Glucagon-Like Peptide-1 in the regulation of β-cell autophagy
Keywords: Akt; protein kinase B; Ambra1; Autophagy And Beclin 1 Regulator 1; AMPK; 5â² AMP-activated protein kinase; Atg; autophagy related proteins; CAMKK; Ca2+/calmodulin-dependent protein kinase kinase; DFCP1; double FYVE-containing protein 1; DPP4; dipeptidyl
Zn2+ detection by MRI using Ln3+-based complexes: The central role of coordination chemistry
Keywords: AMPA; 2-(aminomethyl)pyridine-N-acetate; BPEN; N,N-bis-(2-pyridyl-methyl)ethylene diamine; BPYREN; N,N-bis-(3-pyrazolyl-methyl)ethylene diamine; CEST; Chemical Exchange Saturation Transfer; DNA; Desoxyribonucleic acid; DPA; N,Nâ²-bis-(2-pyridyl-methyl)am
Cu and Zn coordination to amyloid peptides: From fascinating chemistry to debated pathological relevance
Keywords: AD; Alzheimer's disease; AFM; atomic force microscopy; APP; amyloid precursor protein; Aβ; amyloid-β peptide; DHA; dihydro ascorbic acid; EPR; electron paramagnetic resonance; FAD; familial Alzheimer's disease; hAβ, hIAPP; human peptides; IAPP; isl
Effects of bisphenol A on metabolism and evidences of a mode of action mediated through endocrine disruption
Keywords: Bisphenol A; BPA; Endocrine disruption; Obesity; Type 2 diabetes; Insulin; BAT; brown adipose tissue; BMI; body mass index; bw; body weight; DES; diethylstilbestrol; DM; Diabete mellitus; ED; endocrine disruptor; eGFR; estimated glomerular filtration; ERR
αCGRP, another amyloidogenic member of the CGRP family
Keywords: CGRP; Calcitonin Gene Related Peptide; CT; calcitonin; IAPP; islet amyloid polypeptide; GPCR; G-Protein Coupled Receptor; RAMP; Receptor Activity Modifying Protein; T2D; Type 2 Diabetes; MTC; Medullary Thyroid Carcinoma; MD; Molecular Dynamics; CD; Circul
IAPP in type II diabetes: Basic research on structure, molecular interactions, and disease mechanisms suggests potential intervention strategies
Keywords: 2DIR; two-dimensional infra-red spectroscopy; AFM; atomic force microscopy; AGE; advanced glycation end; CD; circular dichroism; CGRP; calcitonin gene-related peptides; DMSO; Dimethyl Sulfoxide; EGCG; epigallocatechin gallate; EPR; electron paramagnetic r
Dynamic membrane interactions of antibacterial and antifungal biomolecules, and amyloid peptides, revealed by solid-state NMR spectroscopy
Keywords: Antibacterial peptide; Antifungal natural product; Amyloidogenic peptide; IAPP; Membrane environment; Lipid raft; Solid-state NMR;
Inflammasomes and type 2 diabetes: An updated systematic review
Keywords: AIM; Absent In Melanoma; ASC; Apoptosis-associated Speck-like protein; ATF6; Activating Transcription Factor 6; CARD; Caspase Activation and Recruitment Domain; DAMPs; Damage Associated Molecular Patterns; DIO; Diet Induced Obese; IAPP; Islet Amyloid Poly
Amyloidogenesis of the amylin analogue pramlintide
Keywords: IAPP; islet amyloid polypeptide; ESI-IMS-MS; electrospray ionization-ion mobility spectrometry-mass spectrometry; Amylin; Islet associated polypeptide; Pramlintide; Amyloid; Diabetes;
Nano-cage-mediated refolding of insulin by PEG-PE micelle
Keywords: Insulin; DTT; Refolding; PEG-PE micelle; Nano-cage; Negative charge layer; DTT; dithiothreitol; CD; circular dichroism; ThT; thioflavinT; HSPs; heat-shock proteins; apoE; apolipoprotein E; SOD1; superoxide dismutase 1; IAPP; islet amyloid polypeptide; PDI
Heparin interactions with apoA1 and SAA in inflammation-associated HDL
Keywords: Heparan sulfate; Lipoproteins/receptors; Amyloid; Atherosclerosis; Proteoglycans; Mass spectrometry; apoA1; apolipoprotein A1; SAA; Serum amyloid A; HSPG; heparan sulfate proteoglycans; ECM; extracellular matrix; Aβ; amyloid beta; IAPP; islet amyloid pol
Molecular and cellular mechanisms linking inflammation to insulin resistance and β-cell dysfunction
Keywords: AMPK; AMP-activated protein kinase; ATM; adipose tissue macrophages; CCL; chemokine (C-C motif) ligand; CCR2; chemokine (C-C motif) receptor 2; CX3CL1; chemokine (C-X3-C motif) ligand 1; CX3CR1; chemokine (C-X3-C motif) receptor; CXCL; CXC chemokine ligan
Amylin-like immunoreactivity in pancreatic X cells of the black-spotted frog Rana (Pelophylax) nigromaculata
Keywords: Amylin; IAPP; Pancreas; Frog; Amphibian; Immunohistochemistry
Exogenous amyloidogenic proteins function as seeds in amyloid β-protein aggregation
Keywords: Aβ; amyloid β-protein; AD; Alzheimer's disease; Act; actin; αS; α-synuclein; Cas; casein; EM; electron microscopy; Fibro; fibroin; fAβ; Aβ fibrils; fAct; Act fibrils; fCas; casein fibrils; fFibro; fibroin fibrils; fIAPP; IAPP fibrils; fSer; sericin
Amylin activates distributed CNS nuclei to control energy balance
Keywords: IAPP; Obesity; Pramlintide; VTA; Reward
Molecular and cytotoxic properties of hIAPP17-29 and rIAPP17-29 fragments: A comparative study with the respective full-length parent polypeptides
Keywords: Spectroscopy; Type 2 diabetes; Confocal microscopy; Mitochondria; Amyloid; Model membranes; hIAPP; human islet amyloid polypeptide; IAPP; islet amyloid polypeptide; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; rIAPP; rodent islet amy
Deletion of retinoic acid receptor β (RARβ) impairs pancreatic endocrine differentiation
Keywords: ES; embryonic stem; Gcg; glucagon; Iapp; islet amyloid polypeptide; Ins1; insulin 1; KO; knockout; Ngn3; Neurogenin3; RA; all-trans retinoic acid; RAR; retinoic acid receptor; RARE; retinoic acid response element; Sst; somatostatin; WT; wild-type; Retinoi
Proinsulin C-peptide interferes with insulin fibril formation
Keywords: ThT; Thioflavin T; ESI-MS; electrospray ionization mass spectrometry; HDX-MS; hydrogen/deuterium exchange mass spectrometry; EM; electron microscopy; IAPP; islet amyloid polypeptide; Proinsulin C-peptide; Amyloid formation; Diabetes type 1; Mass spect
A mechanistic insight into the amyloidogenic structure of hIAPP peptide revealed from sequence analysis and molecular dynamics simulation
Keywords: IAPP; Aggregation; Sequence analysis; Molecular dynamics; Fibril; Type II diabetes;
Protein-oxidized phospholipid interactions in cellular signaling for cell death: From biophysics to clinical correlations
Keywords: A2E; N-retinylidene-N-retinylethanolamine; 2DM; type 2 diabetes; apo; apolipoprotein; Aβ; Alzheimer β-peptide; AD; Alzheimer's disease; AMD; age-related macular degeneration; AMP; antimicrobial peptides; CMC; critical micelle concentration; cyt c; cytoc
Histidine-rich protein Hpn from Helicobacter pylori forms amyloid-like fibrils in vitro and inhibits the proliferation of gastric epithelial AGS cells
Keywords: Aβ; β-amyloid; AD; Alzheimer's disease; ÎΨm; mitochondrial transmembrane potential; FBS; fetal bovine serum; H. pylori; Helicobacter pylori; HRC; histidine-rich Ca2+ binding protein; IAPP; islet amyloid polypeptide; JC-1; 5,5â²,6,6â²-tetrachloro-1,1