Keywords: Ectopic lymphoid tissue; immunoglobulin; lymphoid aggregate; lymphorganogenesis; AID; Activation-induced cytidine deaminase; BAFF; B cell-activating factor of the TNF family; Bcl; B-cell lymphoma; CD21L; CD21 ligand; CRSsNP; Chronic rhinosinusitis witho
مقالات ISI (ترجمه نشده)
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Keywords: ADAM; a disintegrin and metalloproteinase; APP; amyloid precursor protein; APC; antigen presenting cell; Aβ; β-amyloid; B7-H1; B7-homolog 1; CARD; caspase activation and recruitment domain; CCR; C-C chemokine receptor; CIM; C-protein induced myositis; C
Keywords: Flow cytometry; Intracellular protein; Monoclonal antibody; Primary immunodeficiency disease; Surface protein; ADA; adenosine deaminase; ALPS; autoimmune lymphoproliferative syndrome; APECED; autoimmune polyendocrinopathy-candidiasis-ectodermal dystrop
Keywords: ADA; anti-drug antibodies; AMPK; 5â² adenosine monophosphate-activated protein kinase; aHUS; atypical hemolytic uremic syndrome; AMD; age-related macular degeneration; APC; antigen presenting cells; AT; anaphylatoxin; BTK; Bruton's tyrosine kinase; C1q
Keywords: AD; atopic dermatitis; CSR; class-switch recombination; CXCR5; chemokine (C-X-C motif) receptor type 5; DCs; dendritic cells; DEHP; di-(2-ethylhexyl)phthalate; FFPE; formalin-fixed paraffin-embedded; GC; germinal center; ICOS; inducible T cell co-stimulat
Keywords: Autoimmunity; primary immunodeficiency diseases; BÂ cells; T cells; AID; Activation-induced cytidine deaminase; AIHA; Autoimmune hemolytic anemia; AIRE; Autoimmune regulator; ALPS; Autoimmune lymphoproliferative disease; ANA; Anti-nuclear autoantibody; AP
Keywords: CVID; Common variable immunodeficiency; ICOS; inducible T-cell costimulator; TACI; transmembrane activator and calcium mobilizing ligand interactor; ESID; European society of immune deficiencies; TNF; tumor necrosis factor; IFN-γ; interferon gamma; IL- 6
Keywords: Atopic dermatitis; laser capture microdissection; IL-34; claudins 8 and 4; immune; barrier; AD; Atopic dermatitis; CE; Cornified envelope; CLDN; Claudin; CSF-1R; Colony-stimulating factor 1 receptor; CTLA4; Cytotoxic T-lymphocyte antigen 4; DC; Dendritic
Keywords: Carbon balance; Forest ecosystems; Profile measurement; ADVEX; ICOS;
Keywords: Immunology; primary immunodeficiency; nuclear factor κB; autoimmunity; intravenous immunoglobulin; common variable immunodeficiency; severe combined immunodeficiency; newborn screening; gene therapy; ADA; Adenosine deaminase; ADAM; A disintegrin and meta
FOXP3, ICOS and ICOSL gene polymorphisms in systemic sclerosis: FOXP3 rs2294020 is associated with disease progression in a female Italian population
Keywords: Systemic sclerosis; Single nucleotide polymorphism; FOXP3; ICOS; ICOSL;
A novel mouse model for tracking the fate of CXCR5-expressing T cells
Keywords: Follicular helper T cells; CXCR5; Memory T cells; Humoral immunity; GC; Germinal center; Tfh; Follicular helper T; OVA; Ovalbumin; CXC-R5; C-X-C chemokine receptor type 5; CCR7; C-C chemokine receptor type 7; ICOS; Inducible costimulator; PD-1; Programmed
ICOS activation in combination with electrochemotherapy generates effective anti-cancer immunological responses in murine models of primary, secondary and metastatic disease
Keywords: Cancer; Electrochemotherapy; Immunotherapy; ICOS;
Cyclosporin A indirectly attenuates activation of group 2 innate lymphoid cells in papain-induced lung inflammation
Keywords: BAL; bronchoalveolar lavage; CsA; cyclosporin A; ICOS; inducible T cell costimulator; ICOSL; inducible T cell costimulator ligand; ILC2s; group 2 innate lymphoid cells; NFAT; nuclear factor of activated T-cells; Th2; type 2 helper T; TSLP; thymic stromal
Fine tuning subsets of CD4+ T cells by low-dosage of IL-2 and a new therapeutic strategy for autoimmune diseases
Keywords: aa; Amino acids; A region; Acidic region of IL-2Rβ; AKT; Protein kinase B; AA; Alopecia Areata; CTLA-4; Cytotoxic T lymphocyte antigen-4; cDNA; Complementary DNA; Foxp3; Forkhead box P3; GVHD; Chronic graft-versus-host disease; HCV; Hepatitis C virus; hd
Pathogenic and protective roles of B cells and antibodies in patients with chronic rhinosinusitis
Keywords: Antibodies; antibody deficiency; autoimmunity; chronic rhinosinusitis; B cells; immunodeficiency; mucosal immunity; BAFF; B-cell activating factor of the TNF family; BAFF-R; B-cell activating factor of the TNF family receptor; CRS; Chronic rhinosinusitis;
Experimental asthma persists in IL-33 receptor knockout mice because of the emergence of thymic stromal lymphopoietin-driven IL-9+ and IL-13+ type 2 innate lymphoid cell subpopulations
Keywords: Asthma; type 2 innate lymphoid cells; IL-33 receptor; thymic stromal lymphopoietin; IL-9; mast cells; APC; Allophycocyanin; BAL; Bronchoalveolar lavage; FITC; Fluorescein isothiocyanate; FoxP3; Forkhead box P3; ICOS; Inducible costimulator; ILC; Innate ly
Regulation of cancer immune escape: The roles of miRNAs in immune checkpoint proteins
Keywords: Immune checkpoint proteins (ICPs); miRNAs; Cancer immune escape; Antigen-MHC; antigen-major histocompatibility complex; ICPs; immune checkpoint proteins; 3â²UTR; 3â² untransltated region; PD-1; programmed cell death protein; Tregs; regulatory T cells; H
Human Vδ3+ γδ T cells induce maturation and IgM secretion by B cells
Keywords: APC; antigen presenting cell; DC; dendritic cell; ELISA; enzyme-linked immunosorbent assay; HMB-PP; (E)-4-hydroxy-3-methyl-but-2 enyl pyrophosphate; ICOS; inducible co-stimulatory molecule; IFN; γinterferon-γ; Ig; immunoglobulin; IL; interkeukin; iNKT c
Optimizing conventional DMARD therapy for Sjögren's syndrome
Keywords: 6-MP; 6-mercaptopurine; 6-T-GTP; 6-thioguanine triphosphate; ABT; abatacept; Ach; acetylcholine; ALAT; alanine amino transferase; AZA; azathioprine; BAFF; B cell activating factor; Bcl-6; B cell lymphoma 6; bDMARDs; biological disease modifying antirheuma
The Major Orphan Forms of Ichthyosis Are Characterized by Systemic T-Cell Activation and Th-17/Tc-17/Th-22/Tc-22 Polarization in Blood
Keywords: AD; atopic dermatitis; ARCI; autosomal recessive congenital ichthyosis; CIE; congenital ichthyosiform erythroderma; CLA; cutaneous lymphocyte antigen; EI; epidermolytic ichthyosis; IASI; ichthyosis area severity index; IASI-E; ichthyosis area severity ind
Dendritic cells conditioned by activin A-induced regulatory T cells exhibit enhanced tolerogenic properties and protect against experimental asthma
Keywords: Activin-A; allergic asthma; regulatory T cells; tolerogenic dendritic cells; immune regulation; Act-A-Treg; Activin-A-induced regulatory T; alum; Aluminum hydroxide; BAL; Bronchoalveolar lavage; BM-DCs; Bone marrow-derived dendritic cell; cDC; Convent
Involvement of Ly6C, 4-1BB, and KLRG1 in the activation of lamina propria lymphocytes in the small intestine of sanroque mice
Keywords: Costimulation; Inflammation; Intestine; Proinflammatory cytokine; Roquin; ICOS; inducible costimulator; IELs; intraepithelial lymphocytes; KLRG1; killer cell lectin-like receptor subfamily G member 1; LPLs; lamina propria lymphocytes; LCA; leukocyte commo
Depletion of regulatory T cells by anti-ICOS antibody enhances anti-tumor immunity of tumor cell vaccine in prostate cancer
Keywords: PC; prostate cancer; DC; dendritic cell; FITC; fluorescein isothiocyanate; mGM-CSF; mouse granulocyte macrophage colony-stimulating factor; PBS; PHOSPHATE buffered saline; SA; streptavidin; Tregs; regulatory T cells; ICOS; inducible costimulator; Foxp3; f
Achaete-scute complex homologue 2 accelerates the development of Sjögren's syndrome-like disease in the NOD/ShiLtJ mouse
Keywords: SS; Sjögren's syndrome; Ascl2; achaete-scute complex homologue 2; TFH; Follicular helper T cell; CXCR; C-X-C chemokine receptor; IL; interleukin; TNF; tumor necrosis factor; PD-1; programmed cell death 1; ICOS; inducible T-cell costimulator; BAFF; B-ce
Rapid de novo generation of antigen specific human B cells with expression of Blimpâ1 and AID by in vitro immunization
Keywords: LLME; L-leucyl-L-leucine methyl ester; PBMCs; Peripheral blood mononuclear cells; Tfh; T follicular helper; ICOS; Inducible co-stimulator; DCs; Dendritic cells; BCL-6; B cell lymphoma 6; FBS; Fetal bovine serum; KLH; Keyhole limpet hemocyanin; MFI; Mean f
Modification of cytokine-induced killer cells with folate receptor alpha (FRα)-specific chimeric antigen receptors enhances their antitumor immunity toward FRα-positive ovarian cancers
Keywords: ACT; adoptive cellular immunotherapy; AICD; activation induced cell death; ALL; acute lymphocytic leukemia; AML; acute myeloid leukemia; BsAb; bispecific antibody; CA125; cancer antigen-125; CARs; chimeric antigen receptors; CBMCs; cord blood mononuclear
Ruxolitinib reverses dysregulated T helper cell responses and controls autoimmunity caused by a novel signal transducer and activator of transcription 1 (STAT1) gain-of-function mutation
Keywords: STAT1 gain of function; IFN-γ; ruxolitinib; autoimmunity; TH1 cell; TH17 cell; follicular T helper cell; T helper cell polarization; ATG; Anti-thymocyte globulin; BSA; Body surface area; GOF; Gain of function; IC50; Half-maximal inhibitory concentration
Pregnancy favors the expansion of circulating functional follicular helper T Cells
Keywords: Bcl-6; transcription factor B cell lymphoma-6; CMV; cytomegalovirus; E2-17β; estradiol; ELISA; Enzyme-linked immunosorbent assay; GC; germinal center; HbsAg; hepatitis B superficial antigen; HBV; hepatitis B virus; HIV; Human immunodeficiency virus; IC
Mucosal-associated invariant T cells are depleted and functionally altered in patients with common variable immunodeficiency
Keywords: BAFF-R; B cell activating factor receptor; CVID; common variable immunodeficiency; ESID; European Society for Immunodeficiencies; HMB-PP; (E)-4-hydroxy-3-methyl-2-butenyl pyrophosphate; ICOS; inducible T cell Costimulator; iNKT; invariant natural killer T
Modulation of dendritic cell and T cell cross-talk during aging: The potential role of checkpoint inhibitory molecules
Keywords: APC; antigen-presenting cell; cDC; conventional dendritic cell; CTLA-4; cytotoxic T lymphocyte antigen-4; DC; dendritic cell; DUSP; dual-specific phosphatase; GAL-9; galectin-9; ICOS; inducible T cell co-stimulator; ICOSL; inducible T cell co-stimulator l
Human regulatory B cells control the TFH cell response
Keywords: Regulatory B cells; follicular T helper cells; IL-12; IL-21; antibody production; humoral immune response; Bcl-6; B-cell lymphoma 6; Breg; Regulatory B; DC; Dendritic cell; Foxp3; Forkhead box P3; GC; Germinal center; ICAM; Intercellular adhesion molecule
Mucosal Expression of Type 2 and Type 17 Immune Response Genes Distinguishes Ulcerative Colitis From Colon-Only Crohn's Disease in Treatment-Naive Pediatric Patients
Keywords: Immune Regulation; Gene Expression Profile; Prognostic Factor; AUROC; CD; Crohn's disease; CDc; colon-only Crohn's disease; CDic; ileocolonic Crohn's disease; CI; confidence interval; Cq; quantification cycle; IBD; inflammatory bowel disease; ICOS;
Follicular helper T cells mediate IgE antibody response to airborne allergens
Keywords: Follicular T cells; IL-4; IgE; allergy; allergens; TH2 cells; APC; Antigen-presenting cell; BAL; Bronchoalveolar lavage; eGFP; Enhanced green fluorescent protein; FACS; Fluorescence-activated cell sorting; GC; Germinal center; HDM; House dust mite; ICOS;
Circulating and Tissue-Resident CD4+ T Cells With Reactivity to Intestinal Microbiota Are Abundant in Healthy Individuals and Function Is Altered During Inflammation
Keywords: Immune Regulation; Microbiota; Cytokines; Tissue-resident Memory T cells; CFSE; carboxy-fluorescein succinimidyl ester; IBD; inflammatory bowel disease; ICOS; inducible T-cell costimulator; IFN; interferon; IL; interleukin; LPMC; Lamina propria mononuclea
MicroRNAs: New regulators of IL-22
Keywords: IL-22; interleukin-22; Th22; T helper 22 cell; Th1; T helper 1 cell; Th17; T helper 17 cell; NK22; natural killer 22; NKT; natural killer T cell; ILCs; innate lymphoid cells; RORγt; retinoid orphan receptor γt; STAT3; signal transducer and activator of
Impaired selective cytokine production by CD4+ T cells in Common Variable Immunodeficiency associated with the absence of memory B cells
Keywords: CVID; Common Variable Immunodeficiency; PBMCs; Peripheral blood mononuclear cells; PMA; Phorbol 12-myristrate 13-acetate; SEB; Staphylococcal enterotoxin B; MFI; mean fluorescence intensity; ICOS; Inducible coestimulator; BAFFR; B cell activating factor r
Insights into the development and regulation of T follicular helper cells
Keywords: Th; T helper; Tfh; T follicular helper; IL; interleukin; Ig; Immunoglobulin; STAT; signal transduction and activator of transcription; ICOS; inducible co-stimulator; SLAM; signaling lymphocytic activation molecule; SAP; slam associated protein; GC; germin
Intrinsic functional defects of type 2 innate lymphoid cells impair innate allergic inflammation in promyelocytic leukemia zinc finger (PLZF)-deficient mice
Keywords: Allergic mechanisms; innate lymphoid cells; mouse models; CLP; Common lymphoid progenitor; DAPI; 4â²,6-Diamidino-2-phenylindole; ICOS; Inducible costimulator; ILC; Innate lymphoid cell; ILC2; Type 2 innate lymphoid cell; IL-7Rα; IL-7 receptor α; iNKT;
Nasal IL-4+CXCR5+CD4+ T follicular helper cell counts correlate with local IgE production in eosinophilic nasal polyps
Keywords: B cell; ectopic lymphoid structure; eosinophil; IgE; IL-4; nasal polyp; T follicular helper cell; Bcl-6; Transcription factor B-cell lymphoma 6; Bm; B mature; CRSwNP; Chronic rhinosinusitis with nasal polyps; CSR; Class-switch recombination; FACS; Fluores
Regulatory T cells in allergic diseases
Keywords: Asthma; food allergy; regulatory TÂ cells; forkhead box P3; IL-4; TH2 cells; CNS; Conserved noncoding region; CTLA-4; Cytotoxic T-lymphocyte-associated protein 4; DC; Dendritic cell; FOXP3; Forkhead box P3; GF; Germ-free; ICOS; Inducible T cell costimulat
IL-25 and CD4+ TH2 cells enhance type 2 innate lymphoid cell-derived IL-13 production, which promotes IgE-mediated experimental food allergy
Keywords: IL-25; type 2 innate lymphoid cells; CD4+ TH2 cells; IL-13; food allergy; APC; Allophycocyanin; BM; Bone marrow; CT; Cholera toxin; FITC; Fluorescein isothiocyanate; 4GET; Il4 expression-driven GFP reporter; GFP; Green fluorescent protein; ICOS; Inducib
Role of IL-4 receptor α-positive CD4+ T cells in chronic airway hyperresponsiveness
Keywords: TH2 cell; acute allergic airway disease; chronic asthma; cytokine receptors; IL-4; IL-13; gene-deficient mice; AHR; Airway hyperresponsiveness; BAL; Bronchoalveolar lavage; FITC; Fluorescein isothiocyanate; ICOS; Inducible costimulator; ILC2; Type 2 innat
T helper 2 and T follicular helper cells: Regulation and function of interleukin-4
Keywords: Th2; T helper 2; Tfh; T follicular helper; IL; Interleukin; Ig; Immunoglobulin; STAT; signal transduction and activator of transcription; TCR; T cell receptor; NFAT; nuclear factor of activated T cells; IRF4; Interferon regulatory factor 4; ERK; extracell
Virus-Specific CD4+ T Cells Have Functional and Phenotypic Characteristics of Follicular T-Helper Cells in Patients With Acute and Chronic HCV Infections
Keywords: Viral Hepatitis; Immune Regulation; Antiviral Response; IL21; GC; germinal center; HCV; hepatitis C virus; HIV; human immunodeficiency virus; ICCS; intracellular cytokine staining; ICOS; inducible costimulator of T cells; IFN; interferon; IL; interleukin;
T helper 17 cells may drive neuroprogression in major depressive disorder: Proposal of an integrative model
Keywords: 5-HT; serotonin; CCL20; chemokine (C-C motif) ligand 20; CCR6; CC-chemokine receptor 6; CNS; central nervous system; CRF; corticotrophin releasing factor; CRP; C-reactive protein; EAE; experimental autoimmune encephalomyelitis; GM-CSF; granulocyte-macroph
A signaling-enhanced chimeric receptor to activate the ICOS pathway in T cells
Keywords: ADA; anti-drug antibody; CD3; cluster of differentiation 3; B7RP1; B7 related protein 1; ICOS; inducible costimulator; TCR; T cell receptor; ICOS-CD3; chimeric receptor consisting of full-length ICOS and the cytoplasmic region of CD3 zeta; ITAM; immune
Mechanisms of allergy and clinical immunologyHuman B cells promote T-cell plasticity to optimize antibody response by inducing coexpression of TH1/TFH signatures
Keywords: B cell; T-cell plasticity; IL-21; IFN-γ; coexpression; T-bet; Bcl-6; antibody response; crosstalk; Bcl-6; B cell lymphoma 6; DC; Dendritic cell; DP; Double positive; ICOS; Inducible costimulator; LN; Lymph node; PD-1; Programmed cell death 1; PE; Phycoer
Human Vγ9/Vδ2 T cells: Innate adaptors of the immune system
Keywords: APC; antigen presenting cell; BCG; bacillus Calmette-Guérin; BTN3A; butyrophilin 3A (CD277); DC; dendritic cell; DMAPP; dimethylallyl pyrophosphate; α-GC; α-galactosylceramide; HMB-PP; (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate; ICOS; inducible
Atopic dermatitis and skin diseaseEarly pediatric atopic dermatitis shows only a cutaneous lymphocyte antigen (CLA)+ TH2/TH1 cell imbalance, whereas adults acquire CLA+ TH22/TC22 cell subsets
Keywords: Atopic dermatitis; T cell; cutaneous lymphocyte antigen; IL-13; IL-22; IFN-γ; inducible costimulator; CD69; HLA-DR; AD; Atopic dermatitis; CLA; Cutaneous lymphocyte antigen; ICOS; Inducible costimulator; PE; Phycoerythrin; PMA; Phorbol 12-myristate 13-ac