دانلود مقالات ISI درباره Igf-Ir + ترجمه فارسی

Discovery of 3,5-disubstituted-1H-pyrrolo[2,3-b]pyridines as potent inhibitors of the insulin-like growth factor-1 receptor (IGF-1R) tyrosine kinase

Keywords: IGF-1R; IGF-IR; Pyrrolopyridine; Kinase inhibitor

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Optimization of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine IGF-1R tyrosine kinase inhibitors towards JNK selectivity

Keywords: IGF-1R; IGF-IR; JNK; Pyrrolopyrimidine

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Optimization of a series of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine inhibitors of IGF-1R: Elimination of an acid-mediated decomposition pathway

Keywords: IGF-1R; Pyrrolopyrimidine; IGF-IR; Kinase

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Discovery of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidines: Potent inhibitors of the IGF-1R receptor tyrosine kinase

Keywords: Pyrrolopyrimidine; IGF-1R; Kinase inhibitor; IGF-IR

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Knockdown of IGF-IR by RNAi Inhibits SW480 Colon Cancer Cells Growth In Vitro

Keywords: IGF-IR; Colon cancer; Short hairpin RNA interference; Cell growth

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Type I Insulin-like Growth Factor Receptor Induces Pulmonary Tumorigenesis

Keywords: AAH; adenomatous alveolar hyperplasia; BASC; bronchioalveolar stem cell; CREB; cyclic adenosine monophosphate response element binding protein; CCSP; Clara cell secretory protein; IGF; insulin-like growth factor; IGFBP; insulin-like growth factor binding

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

IGF-I and INS receptor expression in the salivary glands of diabetic Nod mice submitted to long-term insulin treatment

Keywords: Salivary glands; Autoimmune diabetes; Insulin treatment; IGF-IR; Insulin receptor;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Novel 2-phenylquinolin-7-yl-derived imidazo[1,5-a]pyrazines as potent insulin-like growth factor-I receptor (IGF-IR) inhibitors

Keywords: Imidazopyrazines; Insulin-like growth factor-I receptor; IGF-IR; IGF-1R; Tyrosine kinase inhibitor; Tumor growth inhibition; Cancer

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2008 سفارش ترجمه

1,3-Disubstituted-imidazo[1,5-a]pyrazines as insulin-like growth-factor-I receptor (IGF-IR) inhibitors

Keywords: IGF-IR; IR; Tyrosine kinase inhibitors; Oncology; Imidazopyrazines; Imidazo[1,5-a]pyrazines; Insulin-like growth-factor-I receptor; Insulin receptor

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Expression of IGF-I and IGF-I receptor in male and female sterlet, Acipenser ruthenus — Evidence for an important role in gonad maturation

Keywords: Sturgeon; Gonad maturation; IGF-I; IGF-IR; IGF-I receptor; Insulin-like growth factor; Ovary; Testis; Reproductive cycle

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Effects of RACK1 on cell migration and IGF-I signalling in cardiomyoctes are not dependent on an association with the IGF-IR

Keywords: RACK1; IGF-IR; Src; PKC

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

WISP3 suppresses insulin-like growth factor signaling in human chondrocytes

Keywords: CCN6; Chondrocytes; Collagen II; ERK; IGF-IR; IRS-1; SEDT-PA; WISP3

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Insulinlike growth factor I receptor and estrogen receptor β expressions are inversely correlated in colorectal neoplasms and affected by the insulin resistance syndrome

Keywords: IGF-IR; ER-β; Colorectal cancer; Insulin resistance; Confocal microscopy

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

The role of the IGF-I system for vitellogenesis in maturing female sterlet, Acipenser ruthenus Linnaeus, 1758

Keywords: Gonad maturation; IGF-I; IGF-IR; IGF-I receptor; Insulin-like growth factor; Cyclical reproduction; Folliculogenesis; Vitellogenesis; Puberty

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Targeting receptor tyrosine kinase signaling in acute myeloid leukemia

Keywords: AML; Receptor tyrosine kinase; Flt3; c-Kit; IGF-IR; PI3K; mTOR

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2007 سفارش ترجمه

Apoptosis and the cardiac action of insulin-like growth factor I

Keywords: Insulin-like growth factor; Apoptosis; Myocardium; Ischaemia; Reperfusion injury; Signaling; ARC; apoptotic repressor with CARD; ATP; adenosine triphosphate; bFGF; basic fibroblast growth factor (also known as FGF2); BAK; Bcl-2 antagonist/killer protein;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2007 سفارش ترجمه

Transcriptional regulation of the insulin-like growth factor-I receptor gene in breast cancer

Keywords: IGF-IR; Transcription factors; Breast cancer; BRCA1; p53; WT1

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Characterisation of insulin-like growth factor receptors and insulin receptors in the human placenta using lectin affinity methods

Keywords: IGF-IR; IGF-IIR; IR; Lectin chromatography; WGA; BanLec; PHA; Con A; SNA

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

Herceptin: mechanisms of action and resistance

Keywords: Breast; Monoclonal antibodies; Trastuzumab; Tyrosine kinase receptor; p27kip1; IGF-IR

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2006 سفارش ترجمه

Growth factor signalling networks in breast cancer and resistance to endocrine agents: new therapeutic strategies

Keywords: Breast cancer; EGFR; HER2; IGF-IR; Tamoxifen; Gefitinib; Endocrine and gefitinib resistance;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

Blocking the insulin-like growth factor-I receptor as a strategy for targeting cancer

Keywords: Drug Discovery; IGF-IR; Growth factor; Conformational change; Antibodies; Kinase inhibitor;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Involvement of the small protein tyrosine phosphatases TC-PTP and PTP1B in signal transduction and diseases: From diabetes, obesity to cell cycle, and cancer

Keywords: EGFR; epidermal growth factor receptor; GHR; growth hormone receptor; IGF-IR; insulin-like growth factor I receptor; IR; insulin receptor; IRS; insulin receptor substrate; JAK; janus kinase; KO; knockout; LeptinR; leptin receptor; PDGFR; platelet derived

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Functions and regulation of transforming growth factor-beta (TGF-β) in the prostate

Keywords: Prostate; TGF-beta; Smad3; Androgen; Carcinogenesis; IGF-I; Akt; Rapamycin; Therapeutics; TGF-β; transforming growth factor-β; TβRII; TGF-β1 receptor II; TβRI; TGF-β1 receptor I; TβRIII; TGF-β1 receptor III; IGF-I; insulin-like growth hormone fact

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

Responses of keratinocytes to substrate-bound vitronectin:growth factor complexes

Keywords: αvβ3; alpha-v beta-3 integrin; αvβ5; alpha-v beta-5 integrin; CGM; Complete Green's media; DMEM-SFM; Dulbecco's modified eagle medium-serum-free; HBB; Hepe's binding buffer; HS; Heparan sulfate's; IGFBP; Insulin-like growth factor binding protein; IGF

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه

Prognostic and therapeutic relevance of HER2 expression in osteosarcoma and Ewing's sarcoma

Keywords: HER2; Osteosarcoma; Ewing's sarcoma; P-glycoprotein; Trastuzumab; IGF-IR;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2005 سفارش ترجمه