IL-33 inhibits RANKL-induced osteoclast formation through the regulation of Blimp-1 and IRF-8 expression
Keywords: Osteoclastogenesis; IL-33; Blimp-1; IRF-8;
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Soluble ST2 reflects hemodynamic stress in non-ischemic heart failure
Keywords: ST2; suppressor of tumorigenicity 2; sST2; soluble ST2; IL-33; Interleukin-33; ECG; electrocardiogram; NT-proBNP; N-terminal pro-B-type natriuretic peptide; NYHA; New York Heart Association; Dilated cardiomyopathy; ST2; Hemodynamics; Etiology; Prognosis;
L’interleukine-33 : une cible thérapeutique potentielle de la néo-angiogenèse associée à l’asthme
Keywords: IL-33; ST2; Asthme; Endothélium; Épithélium; Th2; Th1IL-33; ST2; Asthma; Endothelium; Epithelium; Th2; Th1
The role of IL-33/ST2L signals in the immune cells
Keywords: IL-33; ST2L; sST2; Immune cells
Molecular adjuvant IL-33 enhances the potency of a DNA vaccine in a lethal challenge model
Keywords: DNA vaccines; Adjuvants; IL-33; CD8 T cells; HIV; LCMV;
Respiratory macrophages and dendritic cells mediate respiratory syncytial virus-induced IL-33 production in TLR3- or TLR7-dependent manner
Keywords: Respiratory syncytial virus (RSV); Innate immune cells; IL-33; TLRs;
The IL-33/ST2 axis: Role in health and disease
Keywords: IL-33; ST2; Autoimmunity; Inflammatory bowel diseases; Table of contents;
Research ReportInterleukin-33 ameliorates ischemic brain injury in experimental stroke through promoting Th2 response and suppressing Th17 response
Keywords: MCAO; middle cerebral artery occlusion; CNS; central nervous system; DAMPs; damage associated molecular pattern molecules; HMGB1; high mobility group box 1; FACS; fluorescence activated cell sorter; Ischemic stroke; MCAO; IL-33; Th1/Th2 balance; Th17 immu
IL-33/ST2 axis controls Th2/IL-31 and Th17 immune response in allergic airway diseases
Keywords: PBMC; peripheral blood mononuclear cells; Th; T helper; IL-33; interleukin 33; IL-31; interleukin 31; IL-17; interleukin 17; T1/ST2; cellular IL-33 receptor; sST2; soluble IL-33 receptor; BDP; beclomethasone dipropionate; AR; allergic rhinitis; AAR; aller
Anti-inflammatory activity of flavonoids in Nepalese propolis is attributed to inhibition of the IL-33 signaling pathway
Keywords: BALF; bronchoalveolar lavage fluid; BMMC; bone marrow-derived mast cells; FBS; fetal bovine serum; IBD; inflammatory bowel diseases; IκB; inhibitory of NF-κB; IKK; IκB kinase; IL; interleukin; IL-1RAcP; IL-1R accessory protein; IL-1R/TLR; IL-1 receptor
IL-33 and soluble ST2 levels as novel predictors for remission and progression of carotid plaque in early rheumatoid arthritis: A prospective study
Keywords: Early rheumatoid arthritis; IL-33; Soluble ST2; Disease remission; Atherosclerosis; Carotid plaque
Cardiomyocyte–fibroblast interaction contributes to diabetic cardiomyopathy in mice: Role of HMGB1/TLR4/IL-33 axis
Keywords: Myocardial fibrosis; Diabetes mellitus; HMGB1; IL-33; TLR4
Decidual stromal cell-derived IL-33 contributes to Th2 bias and inhibits decidual NK cell cytotoxicity through NF-κB signaling in human early pregnancy
Keywords: DSCs; decidual stromal cells; dNKs; decidual natural killer cells; FBS; fetal bovine serum; pNKs; peripheral natural killer cells; PBMCs; peripheral blood mononuclear cells; ST2; suppression of tumorigenicity 2; sST2; soluble ST2; Decidual NK cells; IL-33
Pulmonary receptor for advanced glycation end-products promotes asthma pathogenesis through IL-33 and accumulation of group 2 innate lymphoid cells
Keywords: Asthma; receptor for advanced glycation end-products; IL-33; group 2 innate lymphoid cells; AAI; Allergic airway inflammation; HDM; House dust mite; HMGB1; High-mobility group protein B1; ICAM-1; Intercellular adhesion molecule 1; ILC2; Group 2 innate lym
Asthma and lower airway diseasePediatric severe asthma with fungal sensitization is mediated by steroid-resistant IL-33
Keywords: Severe asthma; fungal sensitization; pediatric; IL-33; innate immunity; steroid resistance; ABPA; Allergic bronchopulmonary aspergillosis; AHR; Airway hyperresponsiveness; BAL; Bronchoalveolar lavage; HDM; House dust mite; ICOS; Inducible costimulator; IL
Persistence of asthma requires multiple feedback circuits involving type 2 innate lymphoid cells and IL-33
Keywords: Type 2 innate lymphoid cells; IL-33; T cells; feedback circuit; chronic asthma; BAL; Bronchoalveolar lavage; γc; Common γc chain of the IL-2 receptor; CRTH2; Chemoattractant receptor-homologous molecule expressed on TH2 lymphocytes; DRA; Dust mite, ragw
A preliminary report of increased plasma levels of IL-33 in bipolar disorder: Further evidence of pro-inflammatory status
Keywords: Bipolar disorder; Mania; Depression; IL-33; sST2
Enhancement of the p38 MAPK and PKA signaling pathways is associated with the pro-melanogenic activity of Interleukin 33 in primary melanocytes
Keywords: IL-33; NHEM; Melanogenesis; p38 MAPK; PKA; CREB
Nuclear IL-33 regulates soluble ST2 receptor and IL-6 expression in primary human arterial endothelial cells and is decreased in idiopathic pulmonary arterial hypertension
Keywords: IL-33; Soluble ST2; Pulmonary hypertension; Human endothelial cells; Nuclear repressor;
IL-33/ST2 pathway contributes to metastasis of human colorectal cancer
Keywords: IL-33; ST2; Colorectal cancer; Tumor metastasis
Cigarette smoke alters IL-33 expression and release in airway epithelial cells
Keywords: CSE; cigarette smoke extracts; MoAb; monoclonal antibody; CM; complete medium; Cigarette smoke; IL-33; COPD; Inflammation; Bronchial epithelial cell;
Ginger extracts influence the expression of IL-27 and IL-33 in the central nervous system in experimental autoimmune encephalomyelitis and ameliorates the clinical symptoms of disease
Keywords: Experimental autoimmune encephalomyelitis; Ginger; IL-27; IL-33; Clinical symptoms
Altered subcellular localization of IL-33 leads to non-resolving lethal inflammation
Keywords: IL-33; Non-resolving inflammation; Eosinophilia; Knock-in mouse; Nuclear alarmin; Immune homeostasis; AM; alveolar macrophages; BM; bone marrow; eos; eosinophils; FCM; flow cytometry; FRC; fibroblastic reticular cell; HEV; high endothelial venule; IHC; im
Increased ILC2s in the eosinophilic nasal polyp endotype are associated with corticosteroid responsiveness
Keywords: Dex; Dexamethasone; IL-5; Interleukin-5; IL-13; Interleukin-13; IL-25; Interleukin-25; IL-33; Interleukin-33; ILC2; Group 2 innate lymphoid cell; LTD4; Leukotriene D4; PBS; Phosphate buffered saline; PGD2; Prostaglandin D2; TSLP; Thymic stromal lymphopoie
Alternaria-derived serine protease activity drives IL-33-mediated asthma exacerbations
Keywords: Alternaria alternata; allergic airway disease; asthma exacerbation; protease; IL-33; AEBSF; 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride; ALT; Alternaria; BALF; BAL fluid; CAT; Cat dander; HDM; House dust mite; MCPT-1; Mast cell protease-1; MMP-
Prostaglandin D2 activates group 2 innate lymphoid cells through chemoattractant receptor-homologous molecule expressed on TH2 cells
Keywords: Group 2 innate lymphoid cell; PGD2; chemoattractant receptor-homologous molecule expressed on TH2 cells; IL-25; IL-33; innate type 2 immunity; adaptive type 2 immunity; CRTH2; Chemoattractant receptor-homologous molecule expressed on TH2 cells; CSF-1; Mac
IL-33 promotes ST2-dependent lung fibrosis by the induction of alternatively activated macrophages and innate lymphoid cells in mice
Keywords: IL-33; lung fibrosis; alternatively activated macrophages; type 2 innate lymphoid cells; APC; Allophycocyanin; Arg1; Arginase 1; BAL; Bronchoalveolar lavage; BMDM; Bone marrow-derived macrophage; CT; Computed tomography; FITC; Fluorescein isothiocyanate
Presence of a novel exon 2E encoding a putative transmembrane protein in human IL-33 gene
Keywords: cDNA; complementary DNA; DMEM; Dulbecco's Modified Eagle's Medium; EDTA; ethylenediaminetetraacetic acid; FBS; fetal bovine serum; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; NP-40; Nonidet P-40; RT-PCR; reverse transcription-polymerase chain rea
High plasma levels of soluble ST2 but not its ligand IL-33 is associated with severe forms of pediatric dengue
Keywords: Dengue; Myocarditis; IL-33; Soluble ST2;
Pre-discharge risk stratification in unselected STEMI: Is there a role for ST2 or its natural ligand IL-33 when compared with contemporary risk markers?
Keywords: Myocardial Infarction; ST2; N-terminal B type natriuretic peptide; prognosis; GRACE score; IL-33;
IL-33 promotes Staphylococcus aureus-infected wound healing in mice
Keywords: IL-33; Bacteria; Infection; Neutrophil; Wound healing;
IL-33 mediates the expressions of IL-5 and IL-13 in Angiostrongylus cantonensis-infected mice
Keywords: Angiostrongylus cantonensis; IL-33;
Novel allergic asthma model demonstrates ST2-dependent dendritic cell targeting by cypress pollen
Keywords: IL-33; dendritic cells; cypress pollen; allergic asthma; ST2; mouse model; eosinophils; T cells; BAL; Bronchoalveolar lavage; CT; Cycle threshold; DC; Dendritic cell; FITC; Fluorescein isothiocyanate; HPRT; Hypoxanthine phosphoribosyltransferase; MLN; Med
Decoding asthma: Translating genetic variation in IL33 and IL1RL1 into disease pathophysiology
Keywords: IL-33; IL-1RL1; ST2; genome-wide association study; nuocytes; innate helper cells; innate type 2 lymphoid cells; expression quantitative trait locus; ASW; African ancestry in Southwest United States; CEU; Utah residents with Northern and Western European
IL-33 promotes airway remodeling in pediatric patients with severe steroid-resistant asthma
Keywords: Asthma; pediatric; airway remodeling; steroid resistance; IL-33; therapy; AAD; Allergic airways disease; AHR; Airway hyperresponsiveness; BAL; Bronchoalveolar lavage; EB; Endobronchial biopsy; HDM; House dust mite; RBM; Reticular basement membrane; STRA;
IL-33 promotes eosinophilia in vivo and antagonizes IL-5-dependent eosinophil hematopoiesis ex vivo
Keywords: Eosinophil; IL-5; IL-33; GM-CSF
Expression of IL-33 in the epidermis: The mechanism of induction by IL-17
Keywords: IL-33; IL-17; Psoriasis; Normal human keratinocytes; Signaling pathway
Interleukin-33 mediates formalin-induced inflammatory pain in mice
Keywords: CNS; central nervous system; ERK; extracellular-signal-regulated kinases; IL-33; interleukin-33; MAPK; mitogen-activated protein kinases; rIL; recombinant IL-33; SEM; standard error; SPSS; Statistical Package for the Social Sciences; PBS; phosphate buffer
IL-33 is more potent than IL-25 in provoking IL-13–producing nuocytes (type 2 innate lymphoid cells) and airway contraction
Keywords: Nuocytes; type 2 innate lymphoid cells; IL-13; IL-25; IL-33; asthma; contractionAHR, Airways hyperreactivity; BAL, Bronchoalveolar lavage; Cit, Citrine; ICOS, Inducible costimulator; ILC2, Type 2 innate lymphoid cells; OVA, Ovalbumin; RWP, Ragweed pollen;
Maternal serum interleukin-33 and soluble ST2 across early pregnancy, and their association with miscarriage
Keywords: Miscarriage; sST2; IL-33; Serum; Pregnancy;
Th2-inducing cytokines IL-4 and IL-33 synergistically elicit the expression of transmembrane TNF-α on macrophages through the autocrine action of IL-6
Keywords: TNF-α, tumor necrosis factor-α; tmTNF-α, transmembrane TNF-α; sTNF-α, soluble TNF-α; TACE, TNF-α-converting enzyme; LPS, lipopolysaccharide; WT, wild-typeMacrophage; TNF-α; IL-4; IL-6; IL-33; Inflammation
IL-33 enhances Siglec-8 mediated apoptosis of human eosinophils
Keywords: Siglec-8; IL-33; Eosinophils; Apoptosis; Reactive oxygen species; ROS; reactive oxygen species; mAb; monoclonal antibody; TMRE; tetramethyl-rhodamine; PARP; poly(ADP-ribose) polymerase; Siglec; sialic acid binding immunoglobulin-like lectin; ITIM; immunor
Distinct serum and synovial fluid interleukin (IL)-33 levels in rheumatoid arthritis, psoriatic arthritis and osteoarthritis
Keywords: Arthritis; IL-33; Inflammation; ST2 receptor; Synovium
IL-33 blockade suppresses the development of experimental autoimmune encephalomyelitis in C57BL/6 mice
Keywords: IL-33; Neutralizing antibody; Experimental autoimmune encephalomyelitis; Inflammation; Demyelination;
Interleukin-33 acts as a pro-inflammatory cytokine and modulates its receptor gene expression in highly metastatic human pancreatic carcinoma cells
Keywords: Colo357; IL-33; ST2/ST2L; cytokines; NF-κB;
Interleukin-33 upregulation in peripheral leukocytes and CNS of multiple sclerosis patients
Keywords: Autoimmunity; Demyelination; IL-33; Inflammation; Astrocytes; EAE
Innate IL-13-producing nuocytes arise during allergic lung inflammation and contribute to airways hyperreactivity
Keywords: Nuocytes; IL-13; asthma; IL-25; IL-33; AHR; Airways hyperreactivity; BAL; Bronchoalveolar lavage; ICOS; Inducible costimulator; IL-4eGFP; IL-4-enhanced green fluorescent protein; IL-13Tom; IL-13 tomato fluorescent protein; OVA; Ovalbumin; PE; Phycoeryth
IL-33 induces innate lymphoid cell-mediated airway inflammation by activating mammalian target of rapamycin
Keywords: IL-33; TH2; innate lymphoid cells; asthma; mammalian target of rapamycin; rapamycin; AHR; Airway hyperresponsiveness; APC; Allophycocyanin; BAL; Bronchoalveolar lavage; ICOS; Inducible costimulator; ILC; Innate lymphoid cell; Lin; Lineage-specific marker;
Dynamic role of epithelium-derived cytokines in asthma
Keywords: Asthma; Epithelium; IL-25; IL-33; TSLP
Interleukin-33: A novel player in osteonecrosis of the femoral head?
Keywords: Osteonecrosis femoral head; IL-33; Alarmin; Bone remodeling