Intracerebroventricular infusion of neuropeptide Y modulates VIP secretion in the fasting conscious dog
Keywords: VIP; NPY; Glucagon; Insulin; Intracerebroventricular;
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Peripheral anti-nociceptive effect of nociceptin/orphanin FQ in inflammation and stress-induced colonic hyperalgesia in rats
Keywords: IBS; intestinal bowel syndrome; CRF; corticotropin-releasing factor; N/OFQ; nociceptin/orphanin/FQ; NOP receptor; nociceptin/orphanin peptide receptor; MPO; myeloperoxidase; ICV; intracerebroventricular; IP; intraperitoneal; IT; intrathecal; IC; intracolo
Research ReportNon-opioid antinociception produced by brain stem injections of improgan: Significance of local, but not cross-regional, cannabinoid mechanisms
Keywords: ANOVA; analysis of variance; DPAG; dorsal periaqueductal gray; EMB; explosive motor behavior; HP; hot plate; i.c.; intracerebral; icv; intracerebroventricular; PAG; periaqueductal gray; RM; raphe magnus; TF; tail flick; VLPAG; ventrolateral periaqueductal
Intrinsic neuronal plasticity in the juxtacapsular nucleus of the bed nuclei of the stria terminalis (jcBNST)
Keywords: 4-AP; 4-aminopyridine; α-DTX; α-dendrotoxin; AMPA; α-hydroxy-5-methyl-4-isoazolepropionic acid; APir; amygdalopiriform transition area; jcBNST; juxtacapsular nucleus of the anterior division of the BNST; BLA; basolateral nucleus of the amygdala; BNST;
β2-adrenoceptors are essential for desipramine, venlafaxine or reboxetine action in neuropathic pain
Keywords: Antiallodynic; Antidepressant; Beta2 adrenoceptor; Alpha2 adrenoceptor; Gabapentin; Neuropathic pain; Desipramine; Venlafaxine; Intracerebroventricular; Intrathecal
Effects of acidic-astressin and ovine-CRF microinfusions into the ventral hippocampus on defensive behaviors in rats
Keywords: aCSF; artificial cerebrospinal fluid; aSVG-30; antisauvagine; BLA; basolateral amygdale; CRF; corticotropin-releasing factor; EPM; elevated plus-maze; [Glu11,16]Ast; acidic-astressin; h/rCRF; human/rat CRF; i.c.v.; intracerebroventricular; LTP; long-term
The Rac GTPase-activating bacterial protein toxin CNF1 induces analgesia up-regulating μ-opioid receptors
Keywords: Pain; Cytoskeleton; Rho GTPases; μ-Opioid receptors; Behavior; Bacterial protein toxins; Mice; CNF1; Cytotoxic Necrotizing Factor 1; icv; intracerebroventricular; i.p.; intraperitoneal; i.pl.; intraplantar; MORs; μ-opioid receptors; PAG; periaqueductal
Development of fetal brain renin-angiotensin system and hypertension programmed in fetal origins
Keywords: ACE; angiotensin converting enzyme; ACTH; adrenocorticotropic hormone; Ang; angiotensin; AP; area postrema; AT1R; angiotensin II receptor subtype 1; AT2R; angiotensin II receptor subtype 2; ATIP; AT2R-interacting protein; AVP; arginine vasopressin; BBB; b
Associate editor: John SchetzEthnobotany as a pharmacological research tool and recent developments in CNS-active natural products from ethnobotanical sources
Keywords: Methylxanthines; Hypericum perforatum; Hoodia; Piper methysticum; Salvia divinorum; CNS; central nervous system; ICV; intracerebroventricular; SJW; St. John's wort;
The R6 lines of transgenic mice: A model for screening new therapies for Huntington's disease
Keywords: AdBDNF/AdNoggin; adenoviral BDNF + adenoviral noggin; AIF; apoptosis inducing factor; asialoEPO; asialoerythropoietin; BDNF; brain-derived neurotrophic factor; CGS; CGS21680; DA; dopamine; DARPP-32; dopamine and cyclic-adenosine monophosphate regulated ph
Long-term effects of intracerebroventricular insulin microinjection on renal sodium handling and arterial blood pressure in rats
Keywords: Central nervous system; Intracerebroventricular; Insulin; Natriuresis; Blood pressure and lithium clearance
The inhibitory effect of trimethylamine on the anticonvulsant activities of quinine in the pentylenetetrazole model in rats
Keywords: 4AP; 4-aminopyridine; ANOVA; analysis of variance; AP; anterior-posterior; CNS; central nervous system; Cx; connexins; DV; dorsal-ventral; FCD; focal cortical dysplasia; GABA; γ-aminobutyric acid; GTCS; generalized tonic-clonic seizures; i.c.v; int
Supraspinally-administered agmatine attenuates the development of oral fentanyl self-administration
Keywords: NMDA; NOS; Neuroprotection; Intracerebroventricular
Protective effect of nitric oxide synthase inhibition or antioxidants on brain oxidative damage caused by intracerebroventricular arginine administration
Keywords: Arginine; Na+,K+-ATPase; Antioxidants; Intracerebroventricular; Hippocampus; Oxidative stress
Central nervous system administration of interleukin-6 produces splenic sympathoexcitation
Keywords: Sympathetic nerve discharge; Interleukin-6; Intracerebroventricular; Spleen;
Testosterone and nucleus accumbens dopamine in the male Syrian hamster
Keywords: Anabolic androgenic steroid; Testosterone; Amphetamine; Hamster; Nucleus accumbens; Dopamine; Microdialysis; HPLC–EC; Intracerebroventricular; Subcutaneous
An antidepressant behaviour in mice carrying a gene-specific InsP3R1, InsP3R2 and InsP3R3 protein knockdown
Keywords: Antidepressant; Heparin; Knockdown mice; Inositol-1,4,5-trisphosphate receptor; Intracellular calcium; aODN; antisense oligonucleotide; i.c.v.; intracerebroventricular; InsP3Rl; type 1 inositol-1,4,5-trisphosphate receptor; InsP3R2; type 2 inositol-1,4,5-
Research reportEffects of chronic and acute stressors and CRF on depression-like behavior in mice
Keywords: CFS; chronic footshock; TST; tail suspension test; FST; forced swim test; CRF; corticotropin releasing factor; icv; intracerebroventricular; aCSF; artificial cerebrospinal fluid; CMS; chronic mild stress; Corticotropin-releasing factor; Porsolt forced swi
Exaggerated sickness behavior and brain proinflammatory cytokine expression in aged mice in response to intracerebroventricular lipopolysaccharide
Keywords: Brain; Lipopolysaccharide; Age; Glia; Cytokines; Mice; Behavior; Intracerebroventricular
Intracerebroventricular injection of propionic acid, an enteric bacterial metabolic end-product, impairs social behavior in the rat: Implications for an animal model of autism
Keywords: Intracerebroventricular; Behavioral tracking; Play behavior; Autism; Animal model; Neuroinflammatory; Sodium acetate; Propanol; Short chain fatty acids
An initial animal proof-of-concept study for central administration of clozapine to schizophrenia patients
Keywords: Intracerebroventricular; Rats; DBA/2 mice; Elevated plus maze; Open field maze; Auditory gating
N-truncated amyloid-β oligomers induce learning impairment and neuronal apoptosis
Keywords: Aβ; amyloid-β peptide; AD; Alzheimer's disease; cPLA2; cytosolic calcium-dependent phospholipase A2; DAPI; 4,6-diamidino-2-phenylindole; DMEM; Dulbecco's modified eagle's medium; icv; intracerebroventricular; MAFP; methyl arachidonyl fluorophosphonate;
Peripheral or central administration of nitric oxide synthase inhibitor affects feeding behavior in chicks
Keywords: Chicks; Feeding; Intracerebroventricular; Intraperitoneal; NG-nitro-L-arginine methyl ester; Nitric oxide
Intracerebroventricular injection of losartan inhibits angiotensin II-sensitive neurons via GABA inputs in the anterior hypothalamic area of rats
Keywords: Losartan; Angiotensin II; Intracerebroventricular; Hypothalamus; Unit discharge; Rats;
Central interleukin-1 (IL1) signaling is required for pharmacological, but not physiological, effects of leptin on energy balance
Keywords: Inflammation; Hypothalamus; Appetite; Cytokine; icv; intracerebroventricular; IL1ra; interleukin-1 receptor antagonist; AdV; adenoviral; IL1; interleukin-1; CNS; central nervous system; MTII; melanotan II; POMC; pro-opiomelanocortin; ARC; arcuate nucleus;
Galanin enhances and a galanin antagonist attenuates depression-like behaviour in the rat
Keywords: Depression-like behaviour; Forced swim test; Galanin; Galanin antagonist; Intracerebroventricular
The effect of centrally administered erythropoietin on cardiovascular and respiratory system of anaesthetized rats
Keywords: Erythropoietin; Intracerebroventricular; Blood pressure; Heart rate; Respiratory frequency; Tidal volume; Minute ventilation;
The involvement of the central cholinergic system in the pressor and bradycardic effects of centrally administrated melittin in normotensive conscious rats
Keywords: Brain phospholipase A2 (PLA2); Melittin; Mean arterial pressure; Heart rate; Central cholinergic system; Intracerebroventricular
MTII attenuates ghrelin- and food deprivation-induced increases in food hoarding and food intake
Keywords: Fasting; Foraging; Melanotan II; Hamster; Siberian hamster; Intracerebroventricular
Intracerebroventricular administration of Shiga toxin type 2 induces striatal neuronal death and glial alterations: An ultrastructural study
Keywords: HUS, hemolytic–uremic syndrome; i.c.v., intracerebroventricular; Stx, Shiga toxin; STEC, Shiga toxin from enterohemorrhagic Escherichia coli; TEM, transmission electron microscopyShiga toxin 2; Corpus striatum; Intracerebroventricular; Brain injury; Trans
Cardiovascular effects of centrally injected melittin in hemorrhaged hypotensive rats: The investigation of peripheral mechanisms
Keywords: Brain phospholipase A2 (PLA2); Melittin; Mean arterial pressure (MAP); Heart rate (HR); Catecholamine; Vasopressin; Renin activity; Hemorrhagic shock; Intracerebroventricular;
Sensitivity of pressor responses to central hypertonic saline is greatly enhanced even in pre-hypertensive spontaneously hypertensive rats
Keywords: Pressor response; Intracerebroventricular; Hypertonic saline; Phe-Met-Arg-Phe amide; Spontaneously hypertensive rats
Efficacy of olanzapine and haloperidol in an animal model of mania
Keywords: aCSF; artificial cerebrospinal fluid; ICV; intracerebroventricular; IM; Intramuscular; Na,K-ATPase or Na pump; sodium and potassium-activated adenosine triphosphatase; NMDA; N-methyl-d-aspartate; SEM; standard error of mean.; Bipolar disorder; Haloperidol
A role for corticotropin-releasing factor in the long-term expression of behavioral sensitization to cocaine
Keywords: Cocaine; Corticotropin-releasing factor; Pre-exposure; Sensitization; Locomotor activity; Intracerebroventricular
Centrally injected angiotensin II trans-synaptically activates angiotensin II-sensitive neurons in the anterior hypothalamic area of rats
Keywords: Angiotensin II; Intracerebroventricular; Hypothalamus; Unit discharge; W7; Rats
Type II glucocorticoid receptor involvement in habituated activation of lateral hypothalamic area orexin-A-immunopositive neurons during recurring insulin-induced hypoglycemia
Keywords: Type II glucocorticoid receptor; Recurrent insulin-induced hypoglycemia; Orexin-A; Lateral hypothalamic area; Intracerebroventricular; Fos immunocytochemistry
Supraspinally administered agmatine prevents the development of supraspinal morphine analgesic tolerance
Keywords: NMDA; Nitric oxide synthase; Neuroprotection; Intracerebroventricular
Effects of central infusion and immunoneutralization of growth hormone on the timing of puberty and plasma leptin levels in the female rat
Keywords: Immunoneutralization; Tail-nick; Intracerebroventricular
The role of the central thromboxane A2 in cardiovascular effects of a phospholipase A2 activator melittin administrated intracerebroventricularly in normotensive conscious rats
Keywords: Brain phospholipase A2; Melittin; Mean arterial pressure; Heart rate; Thromboxane A2; Intracerebroventricular
Chronic leptin infusion advances, and immunoneutralization of leptin postpones puberty onset in normally fed and feed restricted female rats
Keywords: Intracerebroventricular; Immunoneutralization;
Self-administration of estrogen and dihydrotestosterone in male hamsters
Keywords: Testosterone; Estrogen; Dihydrotestosterone; Anabolic agents; Operant behavior; Self-administration; Intracerebroventricular; Reinforcement; Hamster
Role of melanocortin in the long-term regulation of energy balance: Lessons from a seasonal model
Keywords: α-MSH; α-melanocyte stimulating hormone; AGRP; Agouti-related protein; ARC; arcuate nucleus; CART; cocaine- and amphetamine-regulated transcript; CRF; corticotrophin-releasing factor; icv; intracerebroventricular; LHA; lateral hypothalamus; MC3-R; melan
Involvement of phosphorylated Ca2+/calmodulin-dependent protein kinase II and phosphorylated extracellular signal-regulated protein in the mouse formalin pain model
Keywords: Phospho-CaMKII; Phospho-ERK; Formalin; Nociceptive behavior; Spinal cord; Hippocampus; Hypothalamus; Intrathecal; Intracerebroventricular;
Arginine vasopressin does not contribute to seizures induced by intracerebroventricularly-injected pilocarpine
Keywords: Arginine vasopressin; Pilocarpine; Seizure; Intracerebroventricular; Rat;
Leptin effects on food and water intake in lines of chickens selected for high or low body weight
Keywords: Chickens; Food intake; Intracerebroventricular; Human recombinant leptin; Water intake;
Succinate causes oxidative damage through N-methyl-d-aspartate-mediated mechanisms
Keywords: Disorders of the nervous system; Neurotoxicity; ANOVA; analysis of variance; AP5; d-2-amino-5-phosphonovaleric acid; ATP; adenosine triphosphate; DHBA; dihydroxybenzoic acid; DNPH; 2,4-dinitrophenylhydrazine; fEPSPs; field excitatory post-synaptic potenti
Cocaine pre-exposure enhances CRF-induced expression of c-fos mRNA in the central nucleus of the amygdala: An effect that parallels the effects of cocaine pre-exposure on CRF-induced locomotor activity
Keywords: Corticotropin-releasing factor; Central nucleus of the amygdala; Bed nucleus of the stria terminalis; Sensitization; Intracerebroventricular; Stress;
Investigation of the mechanisms involved in the central effects of glucagon-like peptide-1 on ethanol-induced gastric mucosal lesions
Keywords: Intracerebroventricular; Gastroprotection; Cholinergic system; Nitric oxide; Somatostatin; Rat;
The influence of NMDA receptor agonist and antagonist on morphine state-dependent memory of passive avoidance in mice
Keywords: Morphine; NMDA receptors; NMDA; dl-AP5; Passive avoidance task; Intracerebroventricular; Mice;
Increase of phosphorylation of calcium/calmodulin-dependent protein kinase-II in several brain regions by substance P administered intrathecally in mice
Keywords: Phospho CaMK-II; Substance P; Nociceptive behavior; Spinal cord; Hippocampus; Hypothalamus; Intrathecal; Intracerebroventricular;