Keywords: ISG ها; PRRSV; TLR7; Antivirus factor; ISGs; NF-κB;
مقالات ISI ISG ها (ترجمه نشده)
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Keywords: ISG ها; AD; Alzheimer's disease; TLRs; toll-like receptors; AβPP; amyloid-β protein precursor; NSAIDs; non-steroidal anti-inflammatory drugs; CNS; central nervous system; TNF-α; tumor necrosis factor-α; IL-1β; interleukin 1-β; IL-6; interleukin-6; NO; nit
Interferon α subtypes in HIV infection
Keywords: ISG ها; AIDS; acquired immune deficiency syndrome; APOBEC3G; apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like 3G; ART; antiretroviral therapy; BLT; bone marrow-liver-thymus; Dpi; days post infection; HIV; human immunodeficiency virus; IDO; indoleam
MCPIP1 is a positive regulator of type I interferons antiviral activity
Keywords: ISG ها; Interferon; Antiviral activity; MCPIP1; ISRE; ISGs;
Interferon induced Mx protein from Indian snow trout Schizothorax richardsonii (Gray) lacks critical functional features unlike its mammalian homologues
Keywords: ISG ها; ISGs; interferon stimulated genes; GED; GTPase effector domain; ORF; open reading frame; BSE; bundle signaling element; Poly (I:C); polyinosinic:polycytidylic acid; UTRs; untranslated regions; Schizothorax richardsonii; Interferon stimulated genes; Mx pro
ADAR1 and PKR, interferon stimulated genes with clashing effects on HIV-1 replication
Keywords: ISG ها; ADAR1; adenosine deaminase acting on RNA 1; AGS; Aicardi-Goutières syndrome; APOBEC3; apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3; ds; double-stranded; dsRBD; dsRNA binding domains; eIF2α; translation initiation factor2; HIV-1; hum
SAMHD1 deficient human monocytes autonomously trigger type I interferon
Keywords: ISG ها; SAMHD1; IFN; AGS; TBK1-IRF3; ISGs;
Association between Type I interferon and depletion and dysfunction of endothelial progenitor cells in C57BL/6 mice deficient in both apolipoprotein E and Fas ligand
Keywords: ISG ها; SLE; systemic lupus erythematosus; EPCs; endothelial progenitor cells; IFN-I; type I interferon; FACS; fluorescence-activated cell sorting; FITC-UEA-1; fluorescein isothiocyanate labeled Ulex europaeus agglutinin 1; DII-ac-LDL; 3â²-tetramethylindocarbocy
Identifying causal variants at the interferon lambda locus in case-control studies: Utilizing non-synonymous variant rs117648444 to probe the role of IFN-λ4
Keywords: ISG ها; IFNL or IFN-λ; interferon lambda; GWAS; genome-wide association studies; IFN-RBV; interferon-α-ribavirin; LD; linkage disequilibrium; HCV; Hepatitis c virus; SNP; Single nucleotide polymorphism; ISGs; interferon-stimulated-genes; UTR; untranslated regio
Identification of a novel porcine OASL variant exhibiting antiviral activity
Keywords: ISG ها; JEV; Japanese encephalitis virus; IFNs; interferons; ISGs; IFN-stimulated genes; OAS; 2',5'-oligoadenylate synthetase; PRRs; pattern-recognition receptors; RNase L; ribonuclease L; RIG-I; retinoic acid-inducible gene I; MDA5; melanoma differentiation-
The newly established bovine endometrial gland cell line (BEGC) forms gland acini in vitro and is only IFNÏ-responsive (MAPK42/44 activation) after E2 and P4-pre-incubation
Keywords: ISG ها; Implantation; Uterine glands; Endometrial gland cell culture; Progesterone; Estrogen; Interferon tau; GD; gestational day; TEER; Transepithelial electrical resistance; UG; uterine gland; CE; caruncular epithelium; F3; placental trophoblast cell line from
A potential robust antiviral defense state in the common vampire bat: Expression, induction and molecular characterization of the three interferon-stimulated genes -OAS1, ADAR1 and PKR
Keywords: ISG ها; Desmodus rotundus; Innate immunity; ISGs; OAS1a; OAS1b; ADAR1; PKR;
Interferon lambda receptor 1 (IFNL1R) transcript is highly expressed in rhinovirus bronchiolitis and correlates with disease severity
Keywords: ISG ها; IFN lambda receptor; IFN; ISGs; Bronchiolitis; Rhinovirus; RSV;
Identification of an interferon-stimulated gene, isg15, involved in host immune defense against viral infections in gilthead seabream (Sparus aurata L.)
Keywords: ISG ها; Teleost; isg15 gene; Antiviral activity; SJNNV; VHSV; IFN I; Phagocytes; AGs; acidophilic granulocytes; ANOVA; analysis of variance; CPE; cytoplasmic polyadenylation element; ENA; European Nucleotide Archive; EPC; epithelioma papulosum cyprini; FBS; foeta
Type I interferon and HIV: Subtle balance between antiviral activity, immunopathogenesis and the microbiome
Keywords: ISG ها; IFN; interferon; ISGs; IFNstimulated genes; HCV; hepatitis C virus; IL-10; interleukin-10; PDL-1; programmed death-ligand 1; LCMV; lymphocytic choriomeningitis virus; IFNAR; IFNA receptor; IRFs; IFN regulatory factors; pDCs; plasmacytoid dendritic cells;
Flaviviridae virus nonstructural proteins 5 and 5A mediate viral immune evasion and are promising targets in drug development
Keywords: ISG ها; AAF; IFN-α-activated factor; ATA; Aurintricarboxylic acid; BDV; border disease virus; BPgV; GBV-D; BVDV-1; bovine viral diarrhea virus-1; C; capsid protein; CLRs; C-type lectin receptors; Core; core protein; CSFV; classical swine fever virus; DENV; dengu
Transmissible gastroenteritis virus does not suppress IFN-β induction but is sensitive to IFN in IPEC-J2 cells
Keywords: ISG ها; TGEV; IFN-β; ISGs; Intestinal epithelial cells;
Molecular characterization and expression analysis of interferon-gamma in black seabream Acanthopagrus schlegelii
Keywords: ISG ها; Black seabream; IFN-gamma; Red spotted grouper nervous necrosis virus; JAK-STAT; ISG; AP-1; activator protein 1; bp; base pair; CaMKII; calcium/calmodulin kinase II; GAS; gamma IFN-activated sequences; ORF; open reading frame; GATA3; GATA-binding protein
The anticancer functions of RIG-I-like receptors, RIG-I and MDA5, and their applications in cancer therapy
Keywords: ISG ها; 5â²PP; 5â²-diphosphate; 5â²ppp; 5â²triphosphorylated; Bcl2; B-cell lymphoma-2; BIRC3; baculoviral IAP repeat-containing 3; CARDs; caspase activation and recruitment domains; CRC; colorectal cancer; CTD; C-terminal domain; CTLs; cytotoxic T lymphocytes
A conserved inhibitory role of suppressor of cytokine signaling 1 (SOCS1) in salmon antiviral immunity
Keywords: ISG ها; SOCS; JAK/STAT signaling; IPNV; SAV; Interferons; Atlantic salmon; bp; base pair; JAK; Janus kinase; IFN; Interferon; SH2; SRC-homology 2; ESS; extended SH2 domain; KIR; kinase inhibitory region; SOCS; suppressors of cytokine signaling; STAT; Signal Trans
Vitamin D increases the antiviral activity of bronchial epithelial cells in vitro
Keywords: ISG ها; Cathelicidin; Interferons; Respiratory viruses; 1α(OH)ase; 1-alpha-hydroxylase; 24(OH)ase; 24-hydroxylase; HPBECs; Human Primary Bronchial Epithelial Cells; IFN-β/IFN-λ; Interferon-β/-λ; ISGs; Interferon Stimulated Genes; IL-6/IL-8; Interleukin-6/-8;
Molecular cloning, characterization, and expression of duck 2â²-5â²-oligoadenylate synthetase-like gene
Keywords: ISG ها; OASs; 2â²-5â²-oligoadenylate synthetases; OASL; 2â²-5â²-Oligoadenylate synthetase-like protein; duOASL; duck 2â²-5â²-oligoadenylate synthetase-like protein; DTMUV; Duck Tembusu virus; NTase; nucleotidyltransferase; UBL; ubiquitin-like; IFN; interfer
Altered expression of interferon-stimulated genes is strongly associated with therapeutic outcomes in hepatitis B virus infection
Keywords: ISG ها; Chronic hepatitis B; Antiviral therapy; IFN signaling pathway; STAT1; MX; Peg-IFN; pegylated interferon; HBeAg; hepatitis B e antigen; HBsAg; hepatitis B surface antigen; NAs; nucleot(s)ide analogues; CHB; chronic hepatitis B; ETV; entecavir; ISGs; interf
Structural analysis and insight into Zika virus NS5 mediated interferon inhibition
Keywords: ISG ها; ZIKV; Zika virus; NS5; non-structural protein 5; SIAH2; seven in absentia homolog 2; STAT2; Signal Transducer and Activator of Transcription 2; MTase; methyltransferase; IFN; interferon; IRF9; Interferon Regulatory Factor 9; ISGF3; Interferon-Stimulated G
IL28B gene polymorphisms and Th1/Th2 cytokine levels might be associated with HTLV-associated arthropathy
Keywords: ISG ها; HAA; artropatia associada ao HTLV; HAM/TSP; Paraparesia Espástica Tropical/Mielopatia Associada ao HTLV-1; HTLV-1; human T-lymphotropic virus 1; HTLV-2; human T-lymphotropic virus 2; ISGs; interferon stimulated genes; SNPs; polimorfismos de nucleotÃdeo
Expression and biological activity of two types of interferon genes in medaka (Oryzias latipes)
Keywords: ISG ها; Type I interferon; ISGs; PolyI:C; NNV; Antiviral response; Medaka
Increased irritability, anxiety, and immune reactivity in transgenic Huntington's disease monkeys
Keywords: ISG ها; Emotion; Cytokines; Inflammation; IL-6; TNF-É; ISGs;
Rupestonic acid derivative YZH-106 suppresses influenza virus replication by activation of heme oxygenase-1-mediated interferon response
Keywords: ISG ها; IAV; influenza A virus; HO-1; heme oxygenase-1; Nrf2; erythroid 2-related factor 2; ISGs; IFN-stimulated genes; RdRp; RNA-dependent RNA polymerase; TLRs; toll-like receptors; RLR; RIG-I-like receptors; MKP5; MAPK phosphatase 5; IRF3; interferon regulatory
Comparative transcriptome analyses indicate enhanced cellular protection against FMDV in PK15 cells pretreated with IFN-γ
Keywords: ISG ها; IFN-γ; Interferon gamma; FMDV; Foot and mouth disease virus; ISGs; IFN-stimulated genes; FMD; Foot-and-mouth disease; DGE; Digital gene expression; FDR; False discovery rate; GO; Gene Ontology; KEGG; Kyoto Encyclopedia of Genes and Genomes; qRT-PCR; Quan
Unexpected high rate of early tumor recurrence in patients with HCV-related HCC undergoing interferon-free therapy
Keywords: ISG ها; HCV; hepatitis C virus; DAA; direct-acting antivirals; SVR; sustained virological response; MELD; model for end-stage liver disease; HCC; hepatocellular carcinoma; BCLC; Barcelona Clinic Liver Cancer group; LOD; limit of detection; EOT; end of treatment;
Roles of ITPA and IL28B genotypes in chronic Hepatitis C patients treated with peginterferon plus ribavirin in Tunisian population
Keywords: ISG ها; ITPA; inosine triphosphate; SVR; sustained virological response; HCV; hepatitis C virus; HCC; hepatocellular carcinoma; PEG-IFN; pegylated interferon; GWAS; Genome Wide Association Study; SNPs; single nucleotide polymorphisms; III IFN; interferon III; IL2
Research ArticleHepatitis Delta co-infection in humanized mice leads to pronounced induction of innate immune responses in comparison to HBV mono-infection
Keywords: ISG ها; HDV; Hepatitis Delta Virus; HBV; Hepatitis B Virus; ISGs; interferon stimulated genes; UPA; Urokinase Plasminogen activator; SCID; Severe combined immunodeficiency; HBV; HDV; ISG; uPA mice; Chronic viral hepatitis;
Research ArticleThe spliceosome factor SART1 exerts its anti-HCV action through mRNA splicing
Keywords: ISG ها; IFN; interferon; HCV; hepatitis C virus; ISGs; IFN stimulating genes; IEGs; IFN effector genes; mRNA-Seq; mRNA-sequencing; NGS; next generation DNA sequencing; IPA; ingenuity pathway analysis; ISRE; IRN stimulating response element; IRES; internal ribosom
An anti-interferon activity shared by paramyxovirus C proteins: Inhibition of Toll-like receptor 7/9-dependent alpha interferon induction
Keywords: ISG ها; IFN; interferon; PIVs; parainfluenza viruses; MeV; measles virus; NiV; Nipah virus; ORF; open reading frame; SeV; Sendai virus; ISGs; IFN-stimulated genes; ds; double stranded; PKR; protein kinase R; PAMPs; pathogen-associated molecular patterns; IRF; int
Interleukin-32α modulates promyelocytic leukemia zinc finger gene activity by inhibiting protein kinase CÉ-dependent sumoylation
Keywords: ISG ها; IL-32; interleukin-32; PLZF; promyelocytic leukemia zinc finger gene; PKC; protein kinase C; PMA; phorbol 12-myristate 13-acetate; SUMO-2; small ubiquitin-like modifier-2; ISGs; interferon-stimulated genes; Interleukin 32α; Promyelocytic leukemia zinc fi
Molecular cloning, expression and characterization of Pekin duck interferon-λ
Keywords: ISG ها; OASL; 2â²-5â²-oligoadenylate synthetase-like; chIFN-λ; chicken interferon-lambda; Ct; cycle threshold; C; cysteine; DHBV; duck hepatitis B virus; duIFN-λ; duck interferon-lambda; GAPDH; glyceraldehyde-6-phosphate dehydrogenase; HPAI; highly pathogenic
TRIM39R, but not TRIM39B, regulates type I interferon response
Keywords: ISG ها; BD; Behcet's disease; HLA; human leukocyte antigen; GWAS; genome-wide association study; IL; interleukin; TRIM; tripartite moti; LD; linkage disequilibrium; HEK; human embryonic kidney; PVDF; polyvinylidene difluoride; TBST; Tris-buffered saline contain
Different effects of three interferons L on Toll-like receptor-related gene expression in HepG2 cells
Keywords: ISG ها; Hepatitis C virus; IL28B; Innate immune response; ISGs; Toll-like receptor
Bat Mx1 and Oas1, but not Pkr are highly induced by bat interferon and viral infection
Keywords: ISG ها; Bats; Interferon; ISGs; Promoter; Viral infection
Human T Cell Leukemia Virus Type I Tax-Induced IκB-ζ Modulates Tax-Dependent and Tax-Independent Gene Expression in T Cells
Keywords: ISG ها; Abs; antibodies; AP-1; activator protein 1; ATL; adult T cell leukemia; Bcl3; B cell CLL/lymphoma 3; CBB; Coomassie brilliant blue; CREB; cyclic adenosine 3â²,5â²-monophosphate response element-binding protein; EGFP; enhanced green fluorescent protein;
The mitochondrial pathway and reactive oxygen species are critical contributors to interferon-α/β-mediated apoptosis in Ubp43-deficient hematopoietic cells
Keywords: ISG ها; ROS; reactive oxygen species; IFN; interferon; ISGs; interferon stimulated genes; NAC; N-acetylcysteine; FACS; fluorescence activated cell sorting; UBP43; USP18; Ubiquitin-like protein; ISG15; Interferon-α/β; Apoptosis; Mitochondrial pathway; Reactive o
The design and recombinant protein expression of a consensus porcine interferon: CoPoIFN-α
Keywords: ISG ها; PoIFN-α; porcine interferon alpha; MX1; interferon-induced myxovirus resistance protein 1; OAS1; 2â²,5â²-oligoadenylate synthetase 1; ISG; interferon stimulation gene; VSV; vesicular stomatitis virus; PRV; pseudorabies virus; PRRSV; porcine reproductiv
Dengue virus replication in infected human keratinocytes leads to activation of antiviral innate immune responses
Keywords: ISG ها; DENV; dengue virus; hpi; hours post infection; hBD; human β defensin; DC; dendritic cells; LC; Langerhans cells; MDDCs; myeloid DCs; RNase; Ribonuclease; IRF; interferon regulatory factor; RIG-I; Retinoic Acid Inducible Gene-I; MAD5; Melanoma Differentia
Evolutionary conserved pro-inflammatory and antigen presentation functions of zebrafish IFNγ revealed by transcriptomic and functional analysis
Keywords: ISG ها; B2M; β-2-microglobulin; COX-2; cyclooxygenase-2; dpf; days post-fertilization; dpi; days post-injection; EPC; epithelioma papulosum cyprinid; hpi; hours post-injection; HSCs; hematopoietic stem cells; ISGs; IFN-stimulated genes; IRF; IFN regulatory facto
Inhibition of woodchuck hepatitis virus gene expression in primary hepatocytes by siRNA enhances the cellular gene expression
Keywords: ISG ها; Hepadnavirus; Woodchuck; RNA interference; RNAi; IFN-stimulated genes; ISGs
Three-dimensional probabilistic maps of the occipital sulci of the human brain in standardized stereotaxic space
Keywords: ISG ها; sulcus; visual-cortex; morphology; lunate; calcarine; atlas; ACS; anterior calcarine sulcus; BCS; body of the calcarine sulcus; CSF; cerebrospinal fluid; IOS; inferior occipital sulcus; ISGS; inferior sagittal sulcus; LiS; lingual sulcus; LOS; lateral occ
MxA-independent inhibition of Hantaan virus replication induced by type I and type II interferon in vitro
Keywords: ISG ها; IFN; interferon; HTNV; Hantaan virus; N; nucleocapsid protein; HCPS; hantavirus cardiopulmonary syndrome; HFRS; hemorrhagic fever with renal syndrome; NE; nephropathia epidemica; STAT; signal transducer and activator of transcription; ISGs; IFN-stimulated
Interferons (IFNs) are key cytokines in both innate and adaptive antiviral immune responses-and viruses counteract IFN action
Keywords: ISG ها; Interferons; Innate antiviral immunity; Interferon-regulatory factor; Toll-like receptors; AP-1; activating protein 1; CARD; caspase recruitment domain; CpG DNA; unmethylated double-stranded DNA; DC; dendritic cell; dsRNA; double-stranded RNA; GAS; IFN ga