STAT3 expression in activating EGFR-driven adenocarcinoma of the lung
Keywords: Non-small cell lung cancer; Bronchioloalveolar carcinoma; Adenocarcinoma; STAT3; EGFR; JAK2;
مقالات ISI (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
SAR and in vivo evaluation of 4-aryl-2-aminoalkylpyrimidines as potent and selective Janus kinase 2 (JAK2) inhibitors
Keywords: JAK1; JAK2; JAK3; 4-Aryl-2-aminoalkylpyrimidine;
Androgen metabolism and JAK/STAT pathway genes and prostate cancer risk
Keywords: Androgen pathway; JAK2; HSD17B3; Prostate cancer; Polymorphisms; Genetic susceptibility;
Rapid identification of heterozygous or homozygous JAK2V617F mutations in myeloproliferative neoplasms using melting curve analysis
Keywords: essential thrombocythemia; JAK2; melting curve analysis; myeloproliferative neoplasms; polycythemia vera
New pieces of a puzzle: The current biological picture of MPN
Keywords: MPN; JAK2; Signaling; Epigenetics; STAT3; Leukemia;
Study to establish the role of JAK2 and SMAD1/5/8 pathways in the inhibition of hepcidin by polysaccharides from Angelica sinensis
Keywords: Angelica sinensis; Polysaccharides; Erythropoietin; Hepcidin; Phospho-SMAD1/5/8; JAK2;
Regulation of S100A4 expression via the JAK2-STAT3 pathway in rhomboid-phenotype pulmonary arterial smooth muscle cells exposure to hypoxia
Keywords: JAKs; Janus kinases; STATs; signal transducers and activators of transcription; HIF-1; hypoxia induced factor 1; PASMCs; pulmonary arterial smooth muscle cells; VSMCs; vascular smooth muscle cells; R-SMCs; rhomboid VSMCs; S-SMCs; spindle-shaped SMCs; PAH;
Identification of a HMGA2-EFCAB6 gene rearrangement following next-generation sequencing in a patient with a t(12;22)(q14.3;q13.2) and JAK2V617F-positive myeloproliferative neoplasm
Keywords: Myeloproliferative; HMGA2; EFCAB6; JAK2; V617F
Peroxisome proliferator-activated receptor-γ cross-regulation of signaling events implicated in liver fibrogenesis
Keywords: AdipoR; adiponectin receptor; AMPK; 5â²-AMP-activated protein kinase; AP1; activator protein 1; C/EBP; CCAAT/enhancer binding protein; CHB; chronic hepatitis B; Cidea; mitochondrial cell death-inducing DNA fragmentation factor α-like effector A; CTGF; c
Novel synthetic derivatives of the natural product berbamine inhibit Jak2/Stat3 signaling and induce apoptosis of human melanoma cells
Keywords: Berbamine derivatives (BBMDs); Jak2; Stat3; ApoptosisBBMDs, berbamine derivatives; STAT, signal transducer and activator of transcription; JAKs, Janus kinases; SFKs, Src family kinases; Tyk2, tyrosine kinase 2; CML, chronic myelogenous leukemia
Acquired Uniparental Disomy in Myeloproliferative Neoplasms
Keywords: Myeloproliferative neoplasm; Uniparental disomy; SNP array; TET2; CBL; EZH2; JAK2;
Mesenchymal stem cells enhance lung cancer initiation through activation of IL-6/JAK2/STAT3 pathway
Keywords: IL6; JAK2; STAT3; Lung cancer; Mesenchymal stem cell; Tumor initiation
CIKS (Act1 or TRAF3IP2) mediates Angiotensin-II-induced Interleukin-18 expression, and Nox2-dependent cardiomyocyte hypertrophy
Keywords: Act1; activator of NF-κB; ACM; adult cardiomyocytes; ANF; atrial natriuretic factor; AP-1; activator protein-1; AT1; angiotensin II type 1 receptor; ATRAP; AT1-receptor-associated protein; ARAP1; type 1 Ang II-receptor-associated protein 1; C/EBP; CCAAT/
Role of TET2 and ASXL1 Mutations in the Pathogenesis of Myeloproliferative Neoplasms
Keywords: ASXL1; TET2; Myelofibrosis; Myeloproliferative neoplasms; JAK2;
Clinical Predictors of Outcome in MPN
Keywords: Myelofibrosis; Polycythemia; Thrombocythemia; JAK2; Prognosis;
Disordered Signaling in Myeloproliferative Neoplasms
Keywords: Myeloproliferative neoplasms; JAK2; Erythropoietin-receptor; MPL; Signaling;
Genotype-Phenotype Interactions in the Myeloproliferative Neoplasms
Keywords: Myeloproliferative neoplasms; JAK2; MPL; Hematopoiesis;
Pyrrolo[1,2-f]triazines as JAK2 inhibitors: Achieving potency and selectivity for JAK2 over JAK3
Keywords: Kinase; Janus kinase; JAK; JAK2; JAK3; MPD; Myeloproliferative diseases; JAK-STAT
Two alternatively spliced 5′BCR/3′JAK2 fusion transcripts in a myeloproliferative neoplasm with a three-way t(9;18;22)(p23;p11.3;q11.2) translocation
Keywords: JAK2; BCR; unclassifiable MPN
Prolactin induces Jak2 phosphorylation of RUSHY195
Keywords: Prolactin; Jak2; RUSH; Uteroglobin; HLTF; Phosphorylation
Translocation t(1;9) is a recurrent cytogenetic abnormality associated with progression of essential thrombocythemia patients displaying the JAK2 V617F mutation
Keywords: Translocation; Essential thrombocythemia; JAK2; Myeloproliferative neoplasm; Derivative chromosome;
Actualités 2011 sur la physiopathologie des syndromes myéloprolifératifs classiques hors LMC (polyglobulie de Vaquez, thrombocytémie essentielle et myélofibrose primaire)
Keywords: SMP : syndrome myéloprolifératif; PV : polyglobulie de Vaquez; TE : thrombocytémie essentielle; MPF : myélofibrose primaire; JAK2 : Janus activated kinase 2; MPL : myeloproliferative leukemia (récepteur de la thrombopoiétine); TET2 : Ten eleven tran
Activation of JAK2/STAT pathway in cerebral cortex after experimental traumatic brain injury of rats
Keywords: JAK2; STAT1; STAT3; AG490; Traumatic brain injury; Neurological Severity Scores
2,7-Pyrrolo[2,1-f][1,2,4]triazines as JAK2 inhibitors: Modification of target structure to minimize reactive metabolite formation
Keywords: JAK2; Kinase inhibitors; Pyrrolotriazine; Glutathione
Association of FCGR2A, JAK2 or HNF4A variants with ulcerative colitis in Koreans
Keywords: FCGR2A; JAK2; Korean; HNF4A; Ulcerative colitis
Effects of Leukemia Inhibitory Factor on Proliferation and Odontoblastic Differentiation of Human Dental Pulp Cells
Keywords: Dental pulp cells; Jak2; leukemia inhibitory factor; odontoblast; Stat3
Aurora kinase A critically contributes to the resistance to anti-cancer drug cisplatin in JAK2 V617F mutant-induced transformed cells
Keywords: Aurka; Aurora kinase; Epo; erythropoietin; EpoR; erythropoietin receptor; JAK2; Janus kinase 2; MPNs; myeloproliferative neoplasms; RT-PCR; reverse transcriptase-polymerase chain reaction; STAT5; signal transducers and activators of transcription 5; TAE;
Erythropoietin protects retinal pigment epithelial cells against the increase of permeability induced by diabetic conditions: Essential role of JAK2/ PI3K signaling
Keywords: Erythropoietin; Diabetic macular edema; Permeability; Retinal pigment epithelial cells; JAK2; PI3K/AKT
The two faces of myeloproliferative neoplasms: Molecular events underlying lymphoid transformation
Keywords: Tyrosine kinase; FGFR1; JAK2; Lymphoblastic leukaemia; 8p11
The role of Janus kinase 2 (JAK2) activation in pneumococcal EstA protein-induced inflammatory response in RAW 264.7 macrophages
Keywords: Streptococcus pneumoniae; EstA; JAK2; NO; IFN; Cytokines;
Differential activities of the Drosophila JAK/STAT pathway ligands Upd, Upd2 and Upd3
Keywords: STAT92E; JAK2; Unpaired; Drosophila; RNAi;
Inhibition of JAK2 Signaling by TG101209 Enhances Radiotherapy in Lung Cancer Models
Keywords: Survivin; JAK2; Non-small cell lung carcinoma; Radiation
PLTP regulates STAT3 and NFκB in differentiated THP1 cells and human monocyte-derived macrophages
Keywords: ABCA1; ATP-binding cassette transporter A1; IFNγ; interferon gamma; IL1α; interleukin 1 alpha; JAK2; Janus kinase-2; LPS; lipopolysaccharides; MIP1α; macrophage inflammatory protein 1 alpha; NFκB; nuclear factor kappa-B; PLTP; phospholipid transfer pr
The potential role of JAK2/STAT3 pathway on the anti-apoptotic effect of recombinant human erythropoietin (rhEPO) after experimental traumatic brain injury of rats
Keywords: JAK2; STAT3; Anti-apoptotic; Recombinant human erythropoietin; Traumatic brain injury;
JAK inhibitors in myeloproliferative neoplasms: Rationale, current data and perspective
Keywords: Myelofibrosis; Polycythemia; Thrombocythemia; JAK2; Ruxolitinib; SAR302503; CYT387; Lestaurtinib; SB1518
Vascular smooth muscle Jak2 deletion prevents angiotensin II-mediated neointima formation following injury in mice
Keywords: Jak2; Neointima; Angiotensin II; Vascular injury; Vascular smooth muscle cells;
Virtual screening and synthesis of quinazolines as novel JAK2 inhibitors
Keywords: JAK2; Quinazolines; Virtual screening; SurflexDock; Apoptosis; Stem cell; AG490
Mesenchymal Stem Cells Promote Formation of Colorectal Tumors in Mice
Keywords: Marrow Stromal Cells; Cancer Stem Cells; JAK2; Tumor Development; αSMA; α-smooth muscle actin; CAF; cancer-associated fibroblasts; CCCs; colorectal cancer cells; CDX2; caudal-type homeobox transcription factor 2; DF; dermal fibroblast; EpCAM; epithelial
Pharmacophore filtering and 3D-QSAR in the discovery of new JAK2 inhibitors
Keywords: JAK2; Pharmacophore; 3D-QSAR; Docking
Shooting the messenger: Targeting signal transduction pathways in leukemia and related disorders
Keywords: Leukemia; Myeloproliferative disorders; Signaling pathways; Therapeutics; BCR-ABL; JAK2; STAT5; PI 3-kinase; HDAC
PGD2 and PGE2 regulate gene expression of Prx 6 in primary macrophages via Nrf2
Keywords: AACOCF3; arachidonyl trifluoromethyl ketone; AC; adenylate cyclase; AGC; cAMP-dependent protein kinase A/protein kinase G/protein kinase C; BMM; bone marrow-derived macrophages; CAPE; caffeic acid phenethyl ester; COX; cyclooxygenase; cPLA2; cytosolic pho
Role of Notch and its oncogenic signaling crosstalk in breast cancer
Keywords: 4T1 cells; mouse mammary cancer cell line; ADAM; a disintegrin and metalloprotease; Akt; protein kinase B; ALDH; aldehyde dehydrogenase; ANK; ankyrin; Axin2; the Axin-related protein; BALB/c; an albino, laboratory-bred strain of the house mouse; Bcl-2; B-
Kudzu root: Traditional uses and potential medicinal benefits in diabetes and cardiovascular diseases
Keywords: ACE2; angiotensin-converting enzyme 2; ADP; adenosine diphosphate; AGE; advanced glycation end-products; APV; DL-2-amino-5-phosphonovaleric acid; AT1; angiotensin II type I receptor; Aβ25-35; β-amyloid; Bcl-2; B-cell leukemia/lymphoma-2; BKCa; large-con
Diamino-1,2,4-triazole derivatives are selective inhibitors of TYK2 and JAK1 over JAK2 and JAK3
Keywords: Tyrosine kinase 2; TYK2; Janus associated kinase; JAK1; JAK2; JAK3
A novel chemotype of kinase inhibitors: Discovery of 3,4-ring fused 7-azaindoles and deazapurines as potent JAK2 inhibitors
Keywords: Azaindole; Deazapurine; JAK2; Kinase; Inhibitor
2-Amino-aryl-7-aryl-benzoxazoles as potent, selective and orally available JAK2 inhibitors
Keywords: Janus kinase; JAK1; JAK2; JAK3; Tyk2; Kinase inhibitors; JAK2 inhibitor
The discovery of tricyclic pyridone JAK2 inhibitors. Part 1: Hit to lead
Keywords: JAK2; Kinase; Ligand binding efficiency; Structure based design
Discovery and SAR of potent, orally available 2,8-diaryl-quinoxalines as a new class of JAK2 inhibitors
Keywords: Janus kinase; JAK1; JAK2; JAK3; Tyk2; Kinase inhibitors
Interleukin-6 upregulates the expression of PMP22 in cultured rat Schwann cells via a JAK2-dependent pathway
Keywords: Interleukin-6; Peripheral myelin protein 22; gp130; JAK2; STAT3; Schwann cell
Differential NOD/SCID mouse engraftment of peripheral blood CD34+ cells and JAK2V617F clones from patients with myeloproliferative neoplasms
Keywords: JAK2; Myeloproliferative disease; NOD/SCID mice; Polycythemia vera