دانلود مقالات ISI درباره پروتئین مرتبط با ECH کلچ 1 + ترجمه فارسی

α-Lipoic acid ameliorated oxidative stress induced by perilla oil, but the combination of these dietary factors was ineffective to cause marked deceases in serum lipid levels in rats

Keywords: پروتئین مرتبط با ECH کلچ 1; Perilla oil; α-Lipoic acid; α-Linolenic acid; Hepatic lipogenesis; Hepatic fatty oxidation; Antioxidant system; Rat; Apex nuclease 1; apurinic/apyrimidinic endodeoxyribonuclease 1; HPLC; high-performance liquid chromatography; Keap1; kelch-like ECH-asso

دانلود رایگان متن کامل مقاله ISI 64 صفحه سال انتشار : 2017 سفارش ترجمه

Isoprostanes, neuroprostanes and phytoprostanes: An overview of 25 years of research in chemistry and biology

Keywords: پروتئین مرتبط با ECH کلچ 1; Isoprostanes; Neuroprostanes; Phytoprostanes; Lipid Peroxidation; Polyunsaturated fatty acids; AA; Arachidonic acid; AD; Alzheimer's disease; AdA; Adrenic acid; ALA; α-Linolenic acid; APCI; Atmospheric pressure chemical ionization; BHT; Butylated hydroxy

دانلود رایگان متن کامل مقاله ISI 71 صفحه سال انتشار : 2017 سفارش ترجمه

Redox signaling in the gastrointestinal tract

Keywords: پروتئین مرتبط با ECH کلچ 1; HNE; 4-hydroxynonenal; 8-OHdG; 8-oxo-7,8-dihydro-2′-deoxyguanosine; AP-1; Activator protein 1; APC; Adenomatous polyposis coli; APE-1; Apurinic/apyrimidinic endonuclease 1; Math1; Atonal homolog 1; Bax; BCL2-associated X protein; β-TrCP; Beta-transduci

دانلود رایگان متن کامل مقاله ISI 150 صفحه سال انتشار : 2017 سفارش ترجمه

Synthesis of Keap1-phosphorylated p62 and Keap1-Nrf2 protein-protein interaction inhibitors and their inhibitory activity

Keywords: پروتئین مرتبط با ECH کلچ 1; p62/Sqstm1; p62; phosphorylated-p62; p-p62; protein-protein interaction; PPI; nuclear factor erythroid 2 related factor-2; Nrf2; Kelch-like ECH-associated protein 1; Keap1; human hepatocellular carcinoma; HCC; cerium ammonium nitrite; CAN; fluorescent pol

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Molecular evolution of antioxidant and hypoxia response in long-lived, cancer-resistant blind mole rats: The Nrf2-Keap1 pathway

Keywords: پروتئین مرتبط با ECH کلچ 1; Nrf2; nuclear factor erythroid 2-related factor 2; ROS; reactive oxygen species; ARE; antioxidant response element; EpRE; electrophile response element; Keap1; Kelch-like ECH-associated protein 1; EPO; erythropoietin; VEGF; vascular endothelial growth fac

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Oxidative stress-responsive transcription factor NRF2 is not indispensable for the human hepatic Flavin-containing monooxygenase-3 (FMO3) gene expression in HepG2 cells

Keywords: پروتئین مرتبط با ECH کلچ 1; FMO3; Flavin-containing monoxygenase-3; NRF2; Nuclear factor (erythroid-derived 2)-like 2; KEAP1; Kelch-like ECH-associated protein 1; NQO1; NAD(P)H:quinone oxidoreductase-1; HMOX1; heme oxygenase-1; tBHP; tert-butyl hydroperoxide; tBHQ; tert-butyl hydroq

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

ALS-FTLD associated mutations of SQSTM1 impact on Keap1-Nrf2 signalling

Keywords: پروتئین مرتبط با ECH کلچ 1; ALS; Amyotrophic lateral sclerosis; ARE; Antioxidant response element; FTLD; Frontotemporal lobar degeneration; IKKβ; Inhibitor of nuclear factor kappa-B kinase subunit beta; Keap1; Kelch-like ECH-associated protein 1; KIR; Keap1-interacting region; LIR;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Redox signaling regulated by an electrophilic cyclic nucleotide and reactive cysteine persulfides

Keywords: پروتئین مرتبط با ECH کلچ 1; Electrophilic signaling; 8-Nitro-cGMP; NO; Redox signaling; 15d-PGJ2; 15-deoxy-Δ12,14-prostaglandin J2; ERK; extracellular signal-regulated kinase; GSH; glutathione; GST; glutathione S-transferase; HNE; 4-hydroxy-2-nonenal; iNOS; inducible type of NO syn

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Sophoraflavanone G from Sophora alopecuroides inhibits lipopolysaccharide-induced inflammation in RAW264.7 cells by targeting PI3K/Akt, JAK/STAT and Nrf2/HO-1 pathways

Keywords: پروتئین مرتبط با ECH کلچ 1; SG; Sophoraflavanone G; LPS; lipopolysaccharide; NO; nitric oxide; PGE2; prostaglandin E2; iNOS; inducible nitric oxide synthase; COX-2; cyclooxygenase-2; TNF-α; tumor necrosis factor-α; IL-6; interleukin-6; IL-1β; interleukin-1β; PI3K; phosphoinositi

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

A novel nuclear factor erythroid 2-related factor 2 (Nrf2) activator RS9 attenuates brain injury after ischemia reperfusion in mice

Keywords: پروتئین مرتبط با ECH کلچ 1; ANOVA; analysis of variance; AREs; antioxidant-response elements; BARD; bardoxolone methyl; CCA; common carotid artery; HO-1; heme oxygenase-1; IRI; ischemia-reperfusion injury; Keap-1; Kelch-like ECH-associated protein 1; MCAO; middle cerebral artery o

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Hydrogen sulfide ameliorates learning memory impairment in APP/PS1 transgenic mice: A novel mechanism mediated by the activation of Nrf2

Keywords: پروتئین مرتبط با ECH کلچ 1; AD; Alzheimer's disease; Aβ; beta-amyloid; APP; beta-amyloid precursor protein; ARE; antioxidant response element; BACE1; β-site APP-cleaving enzyme 1; CBS; cystathionine-β-synthase; DG; dentate gyrus; GST; glutathione S-transferase; HO-1; heme oxygena

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Sulforaphane induces neurovascular protection against a systemic inflammatory challenge via both Nrf2-dependent and independent pathways

Keywords: پروتئین مرتبط با ECH کلچ 1; ARE; antioxidant response element; HBMEC-3; human brain micro-vascular endothelial cell-3; Keap1; Kelch-like ECH-associated protein 1; MCP-1; monocyte chemoattractant protein-1; Nrf2; NF-erythroid 2-related factor 2; SAE; sepsis-associated encephalopathy;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Increase in antioxidant activity by sheep/goat whey protein through nuclear factor-like 2 (Nrf2) is cell type dependent

Keywords: پروتئین مرتبط با ECH کلچ 1; Antioxidant; C2C12; EA.hy926; Nrf2; Whey protein; AREs; antioxidant response elements; ATF4; activating transcription factor 4; CAT; catalase; CDNB; 1-chloro-2,4-dinitrobenzene; DETAPAC; diethylenetriaminepentaactic acid; DTT; dithiothreitol; EDTA; ethyle

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Bach1 differentially regulates distinct Nrf2-dependent genes in human venous and coronary artery endothelial cells adapted to physiological oxygen levels

Keywords: پروتئین مرتبط با ECH کلچ 1; Bach1; BTB and CNC homology 1, basic leucine zipper transcription factor 1; DJ-1; Parkinson disease-associated protein; EC; Endothelial cells; GCL; Glutamate cysteine ligase; GCLM; Glutamate cysteine ligase modulatory subunit; HCAEC; Human coronary artery

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Epigallocatechin-3-gallate enhances key enzymatic activities of hepatic thioredoxin and glutathione systems in selenium-optimal mice but activates hepatic Nrf2 responses in selenium-deficient mice

Keywords: پروتئین مرتبط با ECH کلچ 1; ALT; alanine aminotransferase; AST; aspartate aminotransferase; BSO; buthionine sulfoximine; CDNB; 1-chloro-2, 4-dinitrobenzene; ECL; enhanced chemiluminescense; EDTA; ethylene diamine tetraacetic acid; EGCG; epigallocatechin-3-gallate; FoxO; Forkhead box

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Polyphenol compounds and PKC signaling

Keywords: پروتئین مرتبط با ECH کلچ 1; AP-1; activated protein-1; ARE; antioxidant response element; BBB; blood brain barrier; CAT; catalase; CHO; Chinese hamster ovary; DAG; diacylglycerol; EGFR; epidermal growth factor receptor; EGR; early growth response; ERK; extracellular signal-regulated

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Directly interact with Keap1 and LPS is involved in the anti-inflammatory mechanisms of (-)-epicatechin-3-gallate in LPS-induced macrophages and endotoxemia

Keywords: پروتئین مرتبط با ECH کلچ 1; Kelch-like ECH-associated protein 1; Nuclear factor erythroid-derived factor 2-related factor 2; Nuclear factor-kappa B; (-)-epicatechin-3-gallate; Reactive oxygen species; Hemeoxygenase-1;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2016 سفارش ترجمه

Coenzyme Q0 regulates NFκB/AP-1 activation and enhances Nrf2 stabilization in attenuation of LPS-induced inflammation and redox imbalance: Evidence from in vitro and in vivo studies

Keywords: پروتئین مرتبط با ECH کلچ 1; AP-1; activator protein-1; ARE; antioxidant response element; ATF2; activating transcription factor 2; CoQ0; coenzyme Q0; COX-2; cyclooxygenase-2; ERK; extracellular signal-regulated kinase; GSH; glutathione; HO-1; heme oxygenase-1; I-κB; inhibitor-κB;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2016 سفارش ترجمه

Impaired Nrf2 regulation of mitochondrial biogenesis in rostral ventrolateral medulla on hypertension induced by systemic inflammation

Keywords: پروتئین مرتبط با ECH کلچ 1; CCO; cytochrome c oxidase; ChIP; chromatin immunoprecipitation; CoQ10; coenzyme Q10; COX; cytochrome c; DHE; dihydroethidium; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; HPLC; high pressure liquid chromatography; HR; heart rate; IC; intracisternal; I

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2016 سفارش ترجمه

Novel RNA-binding activity of NQO1 promotes SERPINA1 mRNA translation

Keywords: پروتئین مرتبط با ECH کلچ 1; ARE; antioxidant response elements; A1AT; α-1-antitrypsin; COPD; chronic obstructive pulmonary disease; CR; coding region; FL; firefly luciferase; GRB; growth factor receptor-bound protein; IP; immunoprecipitation; Keap1; Kelch-like ECH-associated protei

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2016 سفارش ترجمه

Magnolia officinalis (Hou Po) bark extract stimulates the Nrf2-pathway in hepatocytes and protects against oxidative stress

Keywords: پروتئین مرتبط با ECH کلچ 1; ARE; antioxidant response element; GCLC; glutamate-cysteine ligase catalytic subunit; Hepa1c1c7; murine hepatoma cells; HepG2; human hepatoma cells; HMOX1; heme oxygenase-1; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; Keap1; Kelch-like ECH-associated

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2016 سفارش ترجمه

Lce1 Family Members Are Nrf2-Target Genes that Are Induced to Compensate for the Loss of Loricrin

Keywords: پروتئین مرتبط با ECH کلچ 1; CE; cornified cell envelope; EDC; epidermal differentiation complex; FLG; filaggrin; Gly/Ser; glycine/serine; Keap1; Kelch-like ECH-associated protein 1; Lce1; late cornified envelope 1; LKO; Lor knockout; LOR; loricrin; Nrf2; NF-E2-related factor 2; tBHQ

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2016 سفارش ترجمه

Regulation of the CNC-bZIP transcription factor Nrf2 by Keap1 and the axis between GSK-3 and β-TrCP

Keywords: پروتئین مرتبط با ECH کلچ 1; Nrf2; Keap1; GSK-3; PKB/Akt; PI3K; PTEN; β-TrCP; ARE; antioxidant response element; tBHQ; tert-butyl hydroquinone; bZIP; basic-region leucine zipper; CDDO-Im; 1[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole; CNC; cap'n'collar; Cul1; cullin-1; Cu

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2016 سفارش ترجمه

Withaferin A induces Nrf2-dependent protection against liver injury: Role of Keap1-independent mechanisms

Keywords: پروتئین مرتبط با ECH کلچ 1; Akt PKB; protein kinase B; APAP; acetaminophen; ALT; alanine aminotransferase; ARE; antioxidant response element; β-Trcp; beta-transducin repeat containing protein; CDDO-Im; 1[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole; Cul3; cullin-3; DMSO;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2016 سفارش ترجمه

S-propargyl-cysteine attenuates inflammatory response in rheumatoid arthritis by modulating the Nrf2-ARE signaling pathway

Keywords: پروتئین مرتبط با ECH کلچ 1; SPRC; S-propargyl-cysteine; CSE; cystathionine γ-synthase; FLS; fibroblast-like synoviocytes; AIA; adjuvant-induced arthritis; Nrf2; nuclear factor erythroid-2-related factor 2; ARE; antioxidant response element; Keap1; kelch-like ECH-associated protein

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2016 سفارش ترجمه

Synthesis, evaluation, and metabolism of novel [6]-shogaol derivatives as potent Nrf2 activators

Keywords: پروتئین مرتبط با ECH کلچ 1; ARE; antioxidant response element; br; broad; 6G; [6]-gingerol; GFP; green fluorescent protein; gstp 1; glutathione S-transferase pi 1; hpf; hours postfertilization; Keap1; Kelch-like ECH-associated protein 1; LC/MS; liquid chromatography-mass spectrome

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2016 سفارش ترجمه

Intermittent hypoxia confers pro-metastatic gene expression selectively through NF-κB in inflammatory breast cancer cells

Keywords: پروتئین مرتبط با ECH کلچ 1; ADAM19; a disintegrin and metalloproteinase 19; AP-1; activator protein-1; ARE; antioxidant response element; BSP; bisulfite sequencing PCR; CA9; carbonic anhydrase IX; CIH; chronic intermittent hypoxia; COX-2; cyclooxygenase-2; DCF; 2',7'-dichlorofluores

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2016 سفارش ترجمه

Redox biology and the interface between bioenergetics, autophagy and circadian control of metabolism

Keywords: پروتئین مرتبط با ECH کلچ 1; ARE; antioxidant response element; ATP; adenosine triphosphate; 5-hmC; hydroxymethylcytosine; ATG; AuTophaGy related; BNIP; Bcl-2/adenovirus E18 19-kDa-interacting protein; Drp1; dynamin related protein 1; EpRE; electrophile response element; eNOS; endoth

دانلود رایگان متن کامل مقاله ISI 57 صفحه سال انتشار : 2016 سفارش ترجمه

PF-4708671, a specific inhibitor of p70 ribosomal S6 kinase 1, activates Nrf2 by promoting p62-dependent autophagic degradation of Keap1

Keywords: پروتئین مرتبط با ECH کلچ 1; PF-4708671; p70 ribosomal S6 kinase 1 (S6K1); p62; Autophagy; Nuclear factor erythroid 2-related factor 2 (Nrf2); Kelch-like ECH-associated protein 1 (Keap1); GSTA1; glutathione S-transferase A1; Keap1; Kelch-like ECH-associated protein 1; MEF; mouse embr

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Nrf2 promotes survival following exposure to ionizing radiation

Keywords: پروتئین مرتبط با ECH کلچ 1; ARE; antioxidant response element; ARS; acute radiation syndrome; ATM; ataxia telangiectasia mutated; BRCA1; breast cancer type 1 susceptibility protein; ChIP; chromatin immunoprecipitation; CnC; cap 'n׳ collar family of basic leucine zipper transcript

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Selective antagonization of activated Nrf2 and inhibition of cancer cell proliferation by procyanidins from Cinnamomi Cortex extract

Keywords: پروتئین مرتبط با ECH کلچ 1; Nrf2; Cinnamomi Cortex; Cancer cells; Antiproliferation; Procyanidin; Suppression; ARE; antioxidant response element; CCE; Cinnamomi Cortex extract; GST; glutathione S-transferase; Keap1; Kelch-like ECH-associated protein 1; NQO1; NAD(P)H:quinone oxidored

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Activation of Nrf2/HO-1signaling pathway involves the anti-inflammatory activity of magnolol in Porphyromonas gingivalis lipopolysaccharide-stimulated mouse RAW 264.7 macrophages

Keywords: پروتئین مرتبط با ECH کلچ 1; LPS; lipopolysaccharide; P. gingivalis; Porphyromonas gingivalis; HO-1; heme oxygenase-1; ROS; reactive oxygen species; RANKL; receptor activator of nuclear factor-κB (RANKL); NF-Κb; nuclear factor-kappa B; Nrf-2; nuclear factor-erythroid 2-related fact

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Dieckol enhances the expression of antioxidant and detoxifying enzymes by the activation of Nrf2-MAPK signalling pathway in HepG2 cells

Keywords: پروتئین مرتبط با ECH کلچ 1; ALT; alanine aminotransferase; ARE; antioxidant response element; AST; aspartate aminotransferase; BSA; bovine serum albumin; DAPI; 4′,6-diamidino-2-phenylindole; DCF-DA; 2′,7′-dichlorofluorescein diacetate; DMSO; dimethyl sulfoxide; DPPH; 2,2-diphe

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Nrf2-dependent repression of interleukin-12 expression in human dendritic cells exposed to inorganic arsenic

Keywords: پروتئین مرتبط با ECH کلچ 1; Nrf2; nuclear factor-erythroid 2-related-2; As; arsenite; NQO1; NAD(P)H quinone oxidoreductase 1; DC; dendritic cells; BMDC; bone marrow-derived DC; Keap1; Kelch-like ECH-associated protein 1; IFN-γ; interferon-γ; TNF-α; tumor necrosis factor-a; Ab; an

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

The role of Nrf2 in protection against Pb-induced oxidative stress and apoptosis in SH-SY5Y cells

Keywords: پروتئین مرتبط با ECH کلچ 1; Lead; Neurotoxicity; Nrf2; Oxidative stress; Antioxidant gene; ARE; antioxidant response element; BSO; buthionine sulfoximine; DCFH-DA; 2′7′-dichlorodihydrofluorescein diacetate; DMSA; dimercaptosuccinic acid; DPI; diphenyliodonium chloride; EMSA; Ele

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Brusatol provokes a rapid and transient inhibition of Nrf2 signaling and sensitizes mammalian cells to chemical toxicity-implications for therapeutic targeting of Nrf2

Keywords: پروتئین مرتبط با ECH کلچ 1; AMC; 7-amino-4-methylcoumarin; CDDO-Me; methyl-2-cyano-3,12-dioxooleana-1, 9(11)dien-28-oate; DNCB; 2,4-dinitrochlorobenzene; Gclm; glutamate-cysteine ligase regulatory subunit; HIF-1α; hypoxia-inducible factor 1α; IAA; iodoacetamide; Keap1; Kelch-lik

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Quantitative in vitro to in vivo extrapolation of tissues toxicity

Keywords: پروتئین مرتبط با ECH کلچ 1; ADME; absorption, distribution, metabolism, and excretion; ARE; antioxidant responses elements; BBB; blood brain barrier; CsA; cyclosporine A; CYP; cytochrome P450; EPA; Environmental Protection Agency; GCL; glutamate cysteine ligase; GCLC; glutamate cyst

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Multiple binding modes of a small molecule to human Keap1 revealed by X-ray crystallography and molecular dynamics simulation

Keywords: پروتئین مرتبط با ECH کلچ 1; DTT; dithiothreitol; Keap1; Kelch-like ECH-associated protein 1; MD; molecular dynamics; Nrf2; Nuclear factor erythroid 2-related factor 2; PDB; Protein Data Bank; Oxidative stress; Antioxidant response; β-Propeller; Crystal packing; Fragment-based drug

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Regulation of Ahr signaling by Nrf2 during development: Effects of Nrf2a deficiency on PCB126 embryotoxicity in zebrafish (Danio rerio)

Keywords: پروتئین مرتبط با ECH کلچ 1; Ahr; aryl hydrocarbon receptor; Ahrr; aryl hydrocarbon receptor repressor; ARE; antioxidant response element; Cyp1a; cytochrome P540 1a; DLC; dioxin-like compound; DMSO; dimethyl sulfoxide; dpf; days post fertilization; hpf; hours post fertilization; Keap

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

Probing the structural requirements of non-electrophilic naphthalene-based Nrf2 activators

Keywords: پروتئین مرتبط با ECH کلچ 1; Nrf2; Keap1; Protein-protein interaction; Transcription factor; Cul3; Keap1/Nrf2 interaction; BTB; Broad complex, Tramtrack and Bric-à-Brac; LE; Ligand efficiency; DMEM; Dubecco's modified Eagle's medium; FBS; fetal bovine serum; HMOX1; heme oxygenase

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

The antioxidant function of sestrins is mediated by promotion of autophagic degradation of Keap1 and Nrf2 activation and by inhibition of mTORC1

Keywords: پروتئین مرتبط با ECH کلچ 1; Sesn; sestrin; ROS; reactive oxygen species; Prx; peroxiredoxin; Srx; sulfiredoxin; ERK; extracellular signal-regulated kinase; Nrf2; nuclear factor erythroid 2-related factor 2; Keap1; Kelch-like ECH-associated protein 1; mTORC1; mechanistic target of ra

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2015 سفارش ترجمه

Hypermethylation of the Keap1 gene inactivates its function, promotes Nrf2 nuclear accumulation, and is involved in arsenite-induced human keratinocyte transformation

Keywords: پروتئین مرتبط با ECH کلچ 1; ROS; reactive oxygen species; Nrf2; nuclear factor E2-related factor 2; ARE; antioxidant response element; HO-1; heme oxygenase 1; SOD; superoxide dismutase; CAT; catalase; Keap1; Kelch-like ECH-associated protein 1; Bach1; BTB and CNC homolog 1; FBS; fet

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2015 سفارش ترجمه

Dimethyl fumarate attenuates 6-OHDA-induced neurotoxicity in SH-SY5Y cells and in animal model of Parkinson's disease by enhancing Nrf2 activity

Keywords: پروتئین مرتبط با ECH کلچ 1; 6-OHDA; 6-hydroxydopamine; AD; Alzheimer's disease; ARE; antioxidant response elements; DA; dopamine; DMF; dimethyl fumarate; DOPAC; dihydroxyphenylacetic acid; GCLC; glutathione cysteine ligase regulatory subunit; GCLM; glutathione cysteine ligase modu

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2015 سفارش ترجمه

Influence of vitamin C and vitamin E on redox signaling: Implications for exercise adaptations

Keywords: پروتئین مرتبط با ECH کلچ 1; 5-LOX; 5-lipoxygenase; AP-1; activating protein 1; cGMP; cyclic guanosine monophosphate; ERK; extracellular signal-regulated kinase; GSH; glutathione (reduced); GSSG; glutathione (oxidized); H2O2; hydrogen peroxide; HIF-α; hypoxia inducible factor alpha;

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2015 سفارش ترجمه

Bioinformatics analyses provide insight into distant homology of the Keap1-Nrf2 pathway

Keywords: پروتئین مرتبط با ECH کلچ 1; ADT; AutoDock Tools; ARE; antioxidant response element; BLAST; Basic Local Alignment Search Tool; DHSP; Distant Homology Search Pipeline; NTMT; NCBI Taxonomy Mapping Tool; HMM; Hidden Markov Model; HMMER3; HMM-based utility version 3; Keap1; Kelch-like EC

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2015 سفارش ترجمه

Role of Nrf2 in the pathogenesis of atherosclerosis

Keywords: پروتئین مرتبط با ECH کلچ 1; ABCA1; ATP-binding cassette, sub-family A, member 1; ABCG1; ATP-binding cassette, sub-family G, member 1; ApoE; apolipoprotein E; ARE; antioxidant response element; ArgII; arginase II; CDDO-Im; 2-cyano-3,12 dioxooleana-1,9 dien-28-imidazolide; CXCL4; chem

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2015 سفارش ترجمه

Glutathione S-transferase pi expression regulates the Nrf2-dependent response to hormetic diselenides

Keywords: پروتئین مرتبط با ECH کلچ 1; Nrf2; nuclear factor erythroid 2-related factor 2; Keap1; Kelch-like ECH-associated protein 1; ARE; antioxidant response element; EpRE; electrophile response element; HO-1; heme oxygenase-1; ROS; reactive oxygen species; (PhSe)2; diphenyl diselenide; GSTP

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2015 سفارش ترجمه

Dermato-protective properties of ergothioneine through induction of Nrf2/ARE-mediated antioxidant genes in UVA-irradiated Human keratinocytes

Keywords: پروتئین مرتبط با ECH کلچ 1; γ-GCLC; γ-glutamate-cysteine ligage; △Ψm; mitochondrial membrane potential; ARE; antioxidant response element; DAPI; 4′,6-diamidino-2-phenylindole dihydrochloride; DCFH2-DA; 2′,7′-dichlorofluorescin-diacetate; EGT; ergothioneine; FBS; fetal bov

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2015 سفارش ترجمه

Lung endothelial barrier protection by resveratrol involves inhibition of HMGB1 release and HMGB1-induced mitochondrial oxidative damage via an Nrf2-dependent mechanism

Keywords: پروتئین مرتبط با ECH کلچ 1; HMGB1; high-mobility group box 1; VILI; ventilator-induced lung injury; LVT; low tidal volume; HVT; high tidal volume; MLVEC; mouse lung vascular endothelial cell; VE-cadherin; vascular endothelial cadherin; DAMP; damage-associated molecular pattern; ROS;

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2015 سفارش ترجمه

Chronic treatment with the mood-stabilizing drug lithium up-regulates nuclear factor E2-related factor 2 in rat pheochromocytoma PC12 cells in vitro

Keywords: پروتئین مرتبط با ECH کلچ 1; 4-HNE; 4-hydroxynonenal; bcl-2; B cell lymphoma protein-2; EDTA; ethylenediaminetetraacetic acid; EpRE; electrophile response element; ERK; extracellular signal-regulated kinase; GCL; glutamate cysteine ligase; GSK3β; glycogen synthase kinase 3β; GST; g

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه