Increased risk of premature coronary artery disease in Egyptians with ABCA1 (R219K), CETP (TaqIB), and LCAT (4886C/T) genes polymorphism
Keywords: PCAD; HDLc; ABCA1; CETP; LCAT;
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Apolipoprotein A-II is a key regulatory factor of HDL metabolism as appears from studies with transgenic animals and clinical outcomes
Keywords: Atherosclerosis; HDL; Apo A-I; Apo A-II; Lipases; ABCA1; ATP binding cassette transporter A1; ABCG1; ATP binding cassette transporter G1; apo; apolipoprotein; apo B-LP; apo B-containing lipoproteins; CE; cholesterol ester; CETP; CE transfer protein; CVD;
Role of white adipose lipolysis in the development of NASH induced by methionine- and choline-deficient diet
Keywords: Acaca; acetyl-coenzyme A carboxylase alpha; Acly; ATP citrate lyase; Adrb; β-adrenergic receptor; ALT; alanine aminotransferase; Apob; apolipoprotein B; ATGL; adipose triglyceride lipase; CD; choline-deficient diet; Ces3; carboxylesterase 3; Dgat; diacyl
Transcriptomics profiling and steroid production in mummichog (Fundulus heteroclitus) testes after treatment with 5α-dihydrotestosterone
Keywords: 11KT; 11-ketotestosterone; ABCC2; ATP-binding cassette, sub-family C (CFTR/MRP), member 2; ABCC3; ATP-binding cassette, sub-family C (CFTR/MRP), member 3; ABCG8; ATP-binding cassette, sub-family G (WHITE), member 8; ACY1; aminoacylase 1; ADAR; adenosine d
Apolipoprotein E derived HDL mimetic peptide ATI-5261 promotes nascent HDL formation and reverse cholesterol transport in vitro
Keywords: ABCA1; ATP binding cassette transporter A1; ABCG1; ATP binding cassette transporter G1; ATI-5261; Apolipoprotein mimetic peptide; CVD; Cardiovascular disease; SR-BI; Scavenger receptor B1; RCT; Reverse cholesterol transport; nHDL; Nascent high density lip
HDL and cognition in neurodegenerative disorders
Keywords: ABC; ATP-binding cassette transporter; AD; Alzheimer's disease; Akt; protein kinase B; ALS; amyotrophic lateral sclerosis; apo; apolipoprotein; Aβ; amyloid-β protein; BBB; blood-brain barrier; CAA; cerebral amyloid angiopathy; CE; cholesterol ester; C
Transfer of lipids to high-density lipoprotein (HDL) is altered in patients with familial hypercholesterolemia
Keywords: apo; apolipoprotein; CE; cholesteryl esters; CHD; coronary heart disease; FH; familial hypercholesterolemia; HDL-C; high-density lipoprotein-cholesterol; LCAT; lecithin-cholesterol-acyl-transferase; LDL-C; low-density lipoprotein-cholesterol; Lp(a); lipop
Impaired fluidity and oxidizability of HDL hydrophobic core and amphipathic surface in dyslipidemic men
Keywords: AAPH; 2,2â²-azobis(2-methylpropionamidine) dihydrochloride; BMI; body mass index; CE; cholesteryl esters; CETP; cholesterol ester transfer protein; CRP; C-reactive protein, CVD, cardiovascular diseases; DTPA; diethylene triamine pentaacetic acid; HOMA-IR
DYRK1A overexpression decreases plasma lecithin:cholesterol acyltransferase activity and apolipoprotein A-I levels
Keywords: Apo; apolipoprotein; BAC; bacterial artificial chromosome; BSA; bovine serum albumin; DS; Down syndrome; DYRKs; dual-specificity tyrosine-(Y)-phosphorylation regulated kinases; ES; embryonic stem; HDL; high-density lipoprotein; HRP; horseradish peroxidase
HDL drug carriers for targeted therapy
Keywords: HDL; high-density lipoprotein; SR-BI; scavenger receptor class B type I; eNOS; endothelial nitric oxide synthase; miRNAs; microRNAs; S1PRs; sphingosine 1-phosphate receptors; S1P; sphingosine 1-phosphate; PGI2; prostaglandin I2; COX-2; cyclooxygenase-2; F
DNA methylation variations at CETP and LPL gene promoter loci: New molecular biomarkers associated with blood lipid profile variability
Keywords: Candidate genes; Blood lipid profile; Missing heritability; DNA methylation; Familial hypercholesterolaemia; ABCA1; ATP-binding cassette A1; apoA1; apolipoprotein A1; apoB; apolipoproprotein B; APOE; apolipoprotein E; AU; arbitrary unit; BMI; body mass in
Fibrate treatment induced quantitative and qualitative HDL changes associated with an increase of SR-BI cholesterol efflux capacities in rabbits
Keywords: Fenofibrate; HDL structure; LCAT; Fatty acid profiles and phospholipid species; SR-BI cholesterol efflux;
Recombinant human LCAT normalizes plasma lipoprotein profile in LCAT deficiency
Keywords: LCAT; Familial LCAT deficiency; Lipoproteins; HDLapoA-I, apolipoprotein A-I; CE, cholesteryl esters; FLD, familial LCAT deficiency; FPLC, fast performance liquid chromatography; FED, fish-eye disease; LCAT, lecithin:cholesterol acyltransferase
L’huile des co-produits de poisson corrige la dyslipidémie, améliore le transport inverse du cholestérol et stimule l’activité de la paraoxonase-1 chez le rat obèse
Keywords: Rat; Obésité; Poisson; Co-produits; Huile; LCAT; Paraoxonase-1Rat; Obesity; Fish; By-products; Oil; LCAT; Paraoxonase-1
A novel modified paclitaxel-loaded discoidal recombinant high-density lipoproteins: Preparation, characterizations and in vivo evaluation
Keywords: Modified d-rHDLs; Structural modification; LCAT; Remodeling; Drug leakage; Targeted drug delivery
The logarithm of the triglyceride/HDL-cholesterol ratio is related to the history of cardiovascular disease in patients with familial hypercholesterolemia
Keywords: AIP; atherogenic index of plasma; APOB; apolipoprotein B gene; BMI; body-mass index; BP; blood pressure; CAD; coronary artery disease; CETP; cholesteryl-ester transfer protein; CVD; cardiovascular diseases; DM; diabetes mellitus; FER(HDL); fractional este
ATP-binding cassette transporter A1 and HDL metabolism: effects of fatty acids
Keywords: ApoA-I; apolipoprotein A-I; ABCA1; ATP-binding cassette transporter A1; CETP; cholesterol ester transfer protein; CHD; coronary heart disease; EPA; eicosapentaenoic acid; HDAC; histone deacetylase; HDL; high-density lipoprotein; HDL-C; HDL cholesterol; LC
Influence of large molecular polymeric pigments isolated from fermented Zijuan tea on the activity of key enzymes involved in lipid metabolism in rat
Keywords: LMPP; large molecular polymeric pigments; FC; free cholesterol; TC; total cholesterol; TG; triacylglycerol; HDL-C; high density lipoprotein-cholesterol; LDL-C; low density lipoprotein-cholesterol; HL; hepatic lipase; HSL; hormone-sensitive lipase; LCAT; l
Hypolipidaemic effects and mechanisms of the main component of Opuntia dillenii Haw. polysaccharides in high-fat emulsion-induced hyperlipidaemic rats
Keywords: ODPs; Opuntia dillenii Haw. polysaccharides; ODP-Ia; Opuntia dillenii Haw. polysaccharide-Ia; TC; total cholesterol; TG; triglyceride; LDL-C; low-density lipoprotein cholesterol; VLDL-C; very low-density lipoprotein cholesterol; AI; atherosclerosis index;
Genetic lecithin:cholesterol acyltransferase deficiency and cardiovascular disease
Keywords: LCAT; HDL; Cardiovascular disease;
Preparation, Characterizations, and In Vitro Metabolic Processes of Paclitaxel-Loaded Discoidal Recombinant High-Density Lipoproteins
Keywords: lipids/lipoproteins; discoidal rHDLs; paclitaxel; LCAT; particle size; structure; physical stability; transformation; remodeling; cancer chemotherapy; targeted drug delivery;
Rotational and hinge dynamics of discoidal high density lipoproteins probed by interchain disulfide bond formation
Keywords: apo; apolipoprotein; apoA-I/HDL; reconstituted HDL; DMPC; dimyristoylphosphatidylcholine; HDL; high density lipoproteins; LL5/5; double belt rotamer forming a pairwise helix 5 domain; LL5/6; double belt rotamer forming pairwise helix 5/6 domains; LL5/4; d
Fish oil supplementation maintains adequate plasma arachidonate in cats, but similar amounts of vegetable oils lead to dietary arachidonate deficiency from nutrient dilution
Keywords: AA; arachidonic acid; ALA; α-linolenic acid; ANOVA; analysis of variance; DHA; docosahexanoic acid; EC; esterified cholesterol; EPA; eicosapentaenoic acid; FA; fatty acid; LA; linoleic acid; LCAT; lecithin/cholesterol acyltransferase; LCn-3 PUFA; long-ch
Difference in lipid packing sensitivity of exchangeable apolipoproteins apoA-I and apoA-II: An important determinant for their distinctive role in lipid metabolism
Keywords: AFM; atomic force microscopy; ALPS; amphipathic lipid packing sensor; apoA-I; apolipoprotein A-I; CE; esterified cholesterol; DPPC; dipalmitoyl-phosphatidylcholine; DPPG; dipalmitoyl-phosphatidylglycerol; DOPC; dioleoyl-phosphatidylcholine; HDL; high dens
NO levels in diabetes mellitus: Effects of l-NAME and insulin on LCAT, Na+/K+ ATPase activity and lipid profile
Keywords: Diabetes; Nitric oxide; Na+/K+ ATPase; LCAT; l-NAME
Trimerized apolipoprotein A-I (TripA) forms lipoproteins, activates lecithin:cholesterol acyltransferase, elicits lipid efflux, and is transported through aortic endothelial cells
Keywords: apoA-I; apolipoprotein A-I; HDL; high-density lipoprotein; ABCA1; ATP-binding cassette transporter A1; ABCG1; ATP-binding cassette transporter G1; SR-BI; scavenger receptor BI; rHDL; reconstituted HDL; POPC; palmitoyl-2-oleyl-phosphatidylcholine; LCAT; le
Plasma levels of sphingosine-1-phosphate and apolipoprotein M in patients with monogenic disorders of HDL metabolism
Keywords: HDL; apoM; Sphingosine-1-phosphate; apoA-I; ABCA1; LCAT; CETP; SCARB1; Endothelial lipase; Hepatic lipase;
ESC/EAS Guidelines for the management of dyslipidaemias
Keywords: 4D Die; Deutsche Diabetes Dialyse Studie; 4S; Scandinavian Simvastatin Survival Study; ABC-1; ATP-binding cassette transporter 1; ACCORD; Action to Control Cardiovascular Risk in Diabetes; ACS; acute coronary syndrome; AIM-HIGH; Atherothrombosis Intervent
Profiles of inflammatory markers and lipoprotein subclasses in patients undergoing continuous ambulatory peritoneal dialysis
Keywords: ESRD (end-stage renal disease); CAPD (continuous ambulatory peritoneal dialysis); IDL; hs-CRP; SAA; LCAT
Lecithin cholesterol acyltransferase (LCAT) activity as a predictor for ketosis and parturient haemoglobinuria in Egyptian water buffaloes
Keywords: Egyptian buffaloes; LCAT; Ketosis; Metabolic diseases; Parturient-haemoglobinuria
Effect in vitro of apolipoprotein A-V on the structure and functions of recombinant high density lipoprotein
Keywords: ApoA-I; apolipoprotein A-I; ApoA-V; apolipoprotein A-V; DMPC; 1,2-dimyristoyl-sn-glycerol-3-phosphatidylcholine; HDL; high density lipoprotein; LCAT; lecithin:cholesterol acyltransferase; MDA; malondialdehyde; oxLDL; oxidized LDL; rHDL; recombinant high d
Substitution of vegetable oil for a partially-hydrogenated fat favorably alters cardiovascular disease risk factors in moderately hypercholesterolemic postmenopausal women
Keywords: Cardiovascular disease; Trans fatty acids; Polyunsaturated fatty acids; Lipoproteins; Partially-hydrogenated fat; Vegetable oil; LDL-cholesterol; HDL-cholesterol; hsCRP; CETP; LCAT
Preβ1-HDL is elevated in the fasting state, but markedly reduced postprandially in poorly controlled type 2 diabetic patients
Keywords: CVD; Cardiovascular disease; TG; Triglyceride; HDL-C; HDL-cholesterol; ApoAI; Apolipoprotein AI; TGRL; Triglyceride rich lipoprotein; LPL; Lipoprotein lipase; CETP; Cholesteryl ester transfer protein; LCAT; Lecithin cholesterol acyltransferase; Prebeta-HD
Plasma preβ1-HDL level is elevated in unstable angina pectoris
Keywords: Preβ1-HDL; Acute coronary syndrome; HDL; Reverse cholesterol transport; LCAT
Cholesterol homeostasis in ABCA1/LCAT double-deficient mouse
Keywords: Cholesterol; HDL; ABCA1; LCAT; Atherosclerosis
HbA1c negatively correlates with LCAT activity in type 2 diabetes
Keywords: HbA1c; LCAT; Type 2 diabetes; HDL
The role of lecithin cholesterol acyltransferase and organic substances from coal in the etiology of Balkan endemic nephropathy: A new hypothesis
Keywords: BEN; LCAT; Pliocene lignite; Organic compounds; Medical geology;
Probucol markedly reduces HDL phospholipids and elevated preβ1-HDL without delayed conversion into α-migrating HDL: Putative role of angiopoietin-like protein 3 in probucol-induced HDL remodeling
Keywords: ABCA1; Endothelial lipase; Inflammation; LCAT; Reverse cholesterol transport
Indices of reverse cholesterol transport in subjects with metabolic syndrome after treatment with rosuvastatin
Keywords: HDL; high density lipoprotein; LDL; low density lipoprotein; LpA-I; HDL containing mainly apoA-I rich particles; CETP; cholesteryl ester transfer protein; LCAT; lecithin cholesterol acyl transferase; Reverse cholesterol transport; Cholesterol efflux; CETP
Use of ProteinChip technology for identifying biomarkers of parasitic diseases: The example of porcine cysticercosis (Taenia solium)
Keywords: Pig; Taenia solium; Cysticercosis; Cestode; Biological markers; Surface Enhanced Laser Desorption-Ionization Time of Flight (SELDI-TOF); Apo A-I; apolipoprotein A-I; Apo A-IV; apolipoprotein A-IV; CHAPS; 3-[(3-cholamidopropyl)dimethylammonio]-1-propanes
Treadmill exercise enhances ABCA1 expression in rat liver
Keywords: Liver ABCA1; HDL-C; Male rats; Treadmill exercise; LCAT; Pre-β-HDL
A dual role for lecithin:cholesterol acyltransferase (EC 2.3.1.43) in lipoprotein oxidation
Keywords: LCAT; lecithin:cholesterol acyltransferase or phosphatidylcholine-sterol O-acyltransferase; au/min; absorbance units per minute; AAPH; 2,2â²-azobis-(2-amidinopropane) hydrochloride; [CD]max; maximum concentration of conjugated dienes; DTT; dithiothreitol
Intrinsic enzymes of high-density lipoprotein
Keywords: CETP; Enzymes; GPx; HDL; Inflammation; LCAT; Lp-PLA2; Oxidation; PLTP; PON1; Reverse cholesterol transport
ApoA-I induces a preferential efflux of monounsaturated phosphatidylcholine and medium chain sphingomyelin species from a cellular pool distinct from HDL3 mediated phospholipid efflux
Keywords: Tandem mass spectrometry; Stable isotope labeling; Electrospray ionization; Quantitative lipid analysis; Lipidomics; ABC; ATP-binding cassette; Ac-LDL; acetylated LDL; Apo; apolipoprotein; CE; cholesteryl ester; E-LDL; enzymatically modified LDL; FC; free
Dyslipidemia in chronic kidney disease: Causes and consequences
Keywords: apo A I; apo C III; hepatic lipase; LCAT; CETP; IDL;
Intraperitoneal leptin regulates lipid metabolism in ethanol supplemented Mus musculas heart
Keywords: Leptin; Cardiomyopathy; Ethanol; Obesity; HMG CoA-reductase; LCAT
Differential diagnosis of familial high density lipoprotein deficiency syndromes
Keywords: High density lipoproteins; HDL deficiency; ABCA1; Tangier disease; Apolipoprotein A-I; LCAT; Fish-eye disease; Monogenetic disease
Apolipoprotein A-I-dependent cholesterol esterification in patients with rheumatoid arthritis
Keywords: Haptoglobin; Apolipoprotein A-I; Cholesterol; LCAT; Rheumatoid arthritis;
Lipid transfer proteins (LTP) and atherosclerosis
Keywords: ACAT; LCAT; CETP; PLTP; Atherosclerosis; HDL;
Phosphatidylcholine-rich acceptors, but not native HDL or its apolipoproteins, mobilize cholesterol from cholesterol-rich insoluble components of human atherosclerotic plaques
Keywords: apo; apolipoproteins; CE; cholesterylester; CETP; cholesterylester transfer proteins; DMPC; dimyristoyl phosphatidylcholine; FC; free cholesterol; ICP; insoluble component of plaques; LCAT; lecithin:cholesterol acyltransferase; PC; phosphatidylcholine; PL