Keywords: لوکوترین C4; RPKM; reads per kilobase of transcript per million mapped reads; FGF; fibroblast growth factor; ETS; E26 transformation-specific or E-twenty-six; LTs; leukotrienes; ALOX5; arachidonate 5-lipoxygenase; LTA4; leukotriene A4; LTB4; leukotriene B4; LTC4; leuk
مقالات ISI لوکوترین C4 (ترجمه نشده)
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Keywords: لوکوترین C4; BAI1; brain-specific angiogenesis inhibitor 1; BDNF; brain derived neurotrophic factor; BRDU; bromodeoxyuridine; C3; complement component 3; CCL11; eotaxin; Cq1; complement component 1; CR3; complement receptor 3; CSF-1R; colony stimulating factor-1 recep
Keywords: لوکوترین C4; LTC4; leukotriene C4; 5-LOX; 5 lipoxygenase; NDGA; nordihydroguaiaretic acid; OA; ovalbumin; PTr; intra-tracheal pressure; SRAW; specific resistance of the airways; Nordihydroguaiaretic acid; Antigen; Airway responsiveness; Leukotrienes; Plethysmography;
Anti-inflammatory effects of luteolin: A review of in vitro, in vivo, and in silico studies
Keywords: لوکوترین C4; NF-κB; nuclear factor kappa B; AP-1; activator protein; STAT3; signal transducer and activator of transcription 3; NK cells; natural killer cells; TNF-α; tumor necrosis factor-α; NO; nitric oxide; iNOS; inducible nitric oxygen synthase; ROS; reactive o
Tanshinone IIA suppresses FcεRI-mediated mast cell signaling and anaphylaxis by activation of the Sirt1/LKB1/AMPK pathway
Keywords: لوکوترین C4; ACC; acetyl-CoA carboxylase; Ac-Lys; acetylated lysine; AMPK; AMP-activated protein kinase; BMMCs; bone marrow-derived mast cells; HSA; human serum albumin; IKK; IκB kinase; IL-6; interleukin-6; JNK; c-Jun N-terminal kinase; LAT; linker for activation of
Is Andrographis paniculata extract and andrographolide anaphylactic?
Keywords: لوکوترین C4; Andrographis paniculata extract; Andrographolide; Active systemic anaphylaxis; Anaphylactoid; β − Hexosaminidase; Leukotriene C4;
Identification, signaling, and functions of LTB4 receptors
Keywords: لوکوترین C4; AA; arachidonic acid; CLDN4; claudin-4; COX; cyclooxygenase; DGS3; desmoglein-3; DSS; dextran sodium sulfate; 5-LOX; 5-lipoxygenase; 5(S)-HETE; 5(S)-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid; 5(S)-HpETE; 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic a
Development of smart cell-free and cell-based assay systems for investigation of leukotriene C4 synthase activity and evaluation of inhibitors
Keywords: لوکوترین C4; 5-LOX; 5-Lipoxygenase; AA; Arachidonic acid; FLAP; 5-Lipoxygenase-activating protein; GSH; Glutathione; LT; Leukotriene; LTA4H; Leukotriene A4 hydrolase; cys-LTs; Cysteinyl leukotrienes; MAPEG; Membrane-associated protein in eicosanoid and glutathione met
Mechanisms of allergy and clinical immunologyRespiratory syncytial virus infection of primary human mast cells induces the selective production of type I interferons, CXCL10, and CCL4
Keywords: لوکوترین C4; Mast cells; viral infection; innate immunity; respiratory infection; chemokines; interferons; respiratory syncytial virus; CBMC; Human cord blood-derived mast cell; DC; Dendritic cell; ISG56; Interferon-stimulated gene 56; LTC4; Leukotriene C4; MOI; Mul
HAMI 3379, a CysLT2R antagonist, dose- and time-dependently attenuates brain injury and inhibits microglial inflammation after focal cerebral ischemia in rats
Keywords: لوکوترین C4; Blood-brain barrier; BBB; CSF; cerebrospinal fluid; CysLT1R; cysteinyl leukotriene receptor 1; CysLT2R; cysteinyl leukotriene receptor 2; CysLTs; cysteinyl leukotrienes; DMSO; dimethyl sulfoxide; GFAP; glial fibrillary acidic protein; Iba-1; ionized cal
Accelerated dissociation of IgE-FcεRI complexes by disruptive inhibitors actively desensitizes allergic effector cells
Keywords: لوکوترین C4; Allergy; basophils; mast cells; IgE; FcεRIα; designed ankyrin repeat proteins; inhibitors; DARPin; Designed ankyrin repeat protein; FITC; Fluorescein isothiocyanate; HRP; Horseradish peroxidase; HSA; Human serum albumin; ID50; Half-maximal disruptive co
Phytochemical and biological studies of Stachys species in relation to chemotaxonomy: A review
Keywords: لوکوترین C4; AA; arachidonic acid; COX-2; cyclooxygenase-2; DNP; dinitrophenyl; DPPH; 1,1-diphenyl 2-picryl hydrazyl; EPM; elevated plus-maze; IC50; inhibitory concentration 50%; IL; interleukin; LTC4; leukotriene C4; MIC; minimum inhibitory concentration; MPO; myelop
Oxidative stress potentially enhances FcεRI-mediated leukotriene C4 release dependent on the late-phase increase of intracellular glutathione in mast cells
Keywords: لوکوترین C4; FcεRI; high-affinity IgE receptor; LT; leukotriene; EP; prostaglandin E2 receptor; BSO; l-buthionine-S,R-sulfoximine; GSH; glutathione; GSSG; oxidized glutathione; GSH-OEt; glutathione reduced form ethyl ester; Mast cell; Glutathione; Leukotriene C4; Oxi
Substrate translocation and stimulated ATP hydrolysis of human ABC transporter MRP3 show positive cooperativity and are half-coupled
Keywords: لوکوترین C4; CDCF; 5(6)-carboxy-2â²,7â²-dichlorofluorescein; DDM; n-dodecyl β-d-maltoside; DMSO; dimethyl sulfoxide; DTT; dithiothreitol; E217βG; β-estradiol 17-(β-d-glucuronide); LTC4; leukotriene C4; MRP; multidrug resistance-associated protein; MTX; methotrex
Effect of endocannabinoids on IgE-mediated allergic response in RBL-2H3 cells
Keywords: لوکوترین C4; 2-AG; 2-arachidonoyl glycerol; 5-LO; 5-lipoxygenase; Akt; protein kinase B; CB; cannabinoid; COX-2; cyclooxygenase-2; cPLA2; cytosolic phospholipase A2; ERK1/2; extracellular signal-regulated kinase 1/2; FAAH; fatty acid amide hydrolase; Gab2; GRB2-associ
Omalizumab increases the intrinsic sensitivity of human basophils to IgE-mediated stimulation
Keywords: لوکوترین C4; Human; basophil; allergy; Fc receptors; ED50; Effective density for 50% maximum response; HR; Histamine release; HSA; Human serum albumin; IL-3R; IL-3 receptor; LTC4; Leukotriene C4; PAG; PIPES-albumin-glucose; PIPES; Piperazine-N,Nâ²-bis(2-ethanesulfoni
Impact of 5-lipoxygenase inhibitors on the spatiotemporal distribution of inflammatory cells and neuronal COX-2 expression following experimental traumatic brain injury in rats
Keywords: لوکوترین C4; 5-LOX; 5-lipoxygenase; ANOVA; analysis of variance; BP; band pass; CA3; region 3 of the hippocampal cornu ammonis; CCI; controlled cortical impact; COX-2; isoform 2 of cyclooxygenase; CSF; cerebrospinal fluid; Cy; carbocyanine; DG; hippocampal dentate gyr
Mangosteen xanthones, α-and γ-mangostins, inhibit allergic mediators in bone marrow-derived mast cell
Keywords: لوکوترین C4; Garcinia Mangostana; α-Mangostin; γ-Mangostin; Bone marrow derived mast cell; Interleukin-6; Prostaglandin D2; Leukotriene C4; Degranulation; Cyclooxygenase-2; Allergy;
Inula japonica extract inhibits mast cell-mediated allergic reaction and mast cell activation
Keywords: لوکوترین C4; IFE; Inulae Flos extract; BMMCs; bone marrow-derived mast cells; IL-3; interleukin-3; LTC4; leukotriene C4; SCF; stem cell factor; cPLA2; cytosolic phospholipase A2; MAPKs; mitogen-activated protein kinases; PLCγ; phospholipase Cγ; AA; arachidonic acid;
Saucerneol D inhibits eicosanoid generation and degranulation through suppression of Syk kinase in mast cells
Keywords: لوکوترین C4; Saucerneol D; Mast cell; Prostaglandin D2; Leukotriene C4; Syk kinase; Mitogen-activated protein kinase;
Coupling of UDP-glucuronosyltransferases and multidrug resistance-associated proteins is responsible for the intestinal disposition and poor bioavailability of emodin
Keywords: لوکوترین C4; AIC; Akaike's information criterion; UGT; UDP-glucuronosyltransferase; UDPGA; uridine diphosphoglucuronic acid; LTC4; leukotriene C4; NTP; National Toxicology Program; SD; Sprague-Dawley; DMEM; Dulbecco's modified Eagle's medium; AP; apical; BL; basolat
CRACM/Orai ion channel expression and function in human lung mast cells
Keywords: لوکوترین C4; CRACM; Orai; Ca2+; asthma; mast cell; histamine; leukotriene C4; cytokine; GSK-7975A; Synta-66; [Ca2+]i; Intracellular free Ca2+; CRAC; Ca2+ release-activated Ca2+; DMSO; Dimethyl sulfoxide; HLMCs; Human lung mast cells; LTC4; Leukotriene C4; MC; Mast c
ABCC6 does not transport vitamin K3-glutathione conjugate from the liver: Relevance to pathomechanisms of pseudoxanthoma elasticum
Keywords: لوکوترین C4; ABC; ATP binding cassette; GGCX; gamma-glutamyl carboxylase enzyme; LTC4; leukotriene C4; MRM; multiple reaction monitoring; PXE; pseudoxanthoma elasticum; VK1, VK2 and VK3; vitamin K1, 2 and 3, respectively; VK3GS; glutathione-mono-conjugate of vitamin K
Glutamine residues in Q-loops of multidrug resistance protein MRP1 contribute to ATP binding via interaction with metal cofactor
Keywords: لوکوترین C4; Sf21; Spodoptera frugiperda 21; ABC; ATP binding cassette; P-gp; P-glycoprotein; BCRP; breast cancer resistance protein; MRP1; multidrug resistance protein 1; NBD; nucleotide binding domain; TMD; transmembrane domain; LTC4; leukotriene C4; 8-N3ATP; 8-azid
Crucial role for autophagy in degranulation of mast cells
Keywords: لوکوترین C4; Mast cell; autophagy; CD63; degranulation; p62; light chain 3 (LC3); Atg; Autophagy related gene; BM; Bone marrow; BMMC; Bone marrow-derived mast cell; DC; Dendritic cell; FcεRI; High affinity receptor for IgE; GM-CSF; Granulocyte macrophage colony-sti
Natural anti-inflammatory products and leukotriene inhibitors as complementary therapy for bronchial asthma
Keywords: لوکوترین C4; Bronchial asthma; Leukotriene C4; Bosewilla serrata; Curcumin; licorice
Functional expression of single-chain antibody to leukotriene C4
Keywords: لوکوترین C4; Single-chain antibody; Leukotriene C4; Arachidonic acid; Monoclonal antibody
Transport of N-acetyl-S-(1,2-dichlorovinyl)-l-cysteine, a metabolite of trichloroethylene, by mouse multidrug resistance associated protein 2 (Mrp2)
Keywords: لوکوترین C4; AA3; aminoacylase 3; DCVC; S-(1,2-dichlorovinyl)-l-cysteine; Ac-DCVC; N-acetyl-S-(1,2-dichlorovinyl)-l-cysteine, Ac-DCVC; DDM; dodecyl β-d-maltopyranoside; E17bG; estradiol 17-β-d-glucuronide; HPLC; high performance liquid chromatography; GSH; reduced g
Cardiovascular disease risk associated with asthma and respiratory morbidity might be mediated by short-acting β2-agonists
Keywords: لوکوترین C4; Adrenergic β-agonists; asthma; cardiovascular system; epidemiology; lung diseases; obstructive; BMI; Body mass index; CATI; Computer-assisted telephone interview; CHD; Coronary heart disease; COPD; Chronic obstructive pulmonary disease; CVD; Cardiovascul
Lung mast cells are a source of secreted phospholipases A2
Keywords: لوکوترین C4; Lung mast cells; secreted phospholipase A2; leukotriene C4; arachidonic acid; BALF; Bronchoalveolar lavage fluid; BMMC; Bone marrow-derived mast cell; cPLA2; Cytosolic phospholipase A2; Ct; Cycle threshold; DTT; Dithiothreitol; GAPDH; Glyceraldehyde-3-p
Targeting Ca2+ release-activated Ca2+ channel channels and leukotriene receptors provides a novel combination strategy for treating nasal polyposis
Keywords: لوکوترین C4; Calcium channel; calcium signal; leukotrienes; cysteinyl leukotriene type I receptor; 5-lipoxygenase; nasal polyposis; Ca2+; Calcium ion; CRAC; Ca2+ release-activated Ca2+; IC50; Inhibitory concentration of 50%; La3+; Lanthanum ion; LTC4; Leukotriene C4
Secreted phospholipases A2: A proinflammatory connection between macrophages and mast cells in the human lung
Keywords: لوکوترین C4; AA; arachidonic acid; Akt; protein kinase B; BA; bronchial asthma; BAL; bronchoalveolar lavage; BBMCs; bone marrow-derived mast cells; COPD; chronic obstructive pulmonary disease; ERK1/2; extracellular-regulated kinase 1/2; HSPG; heparan sulfate proteogly
Vascular endothelial growth factors synthesized by human lung mast cells exert angiogenic effects
Keywords: لوکوترین C4; Human mast cells; vascular endothelial growth factors; vascular endothelial growth factor receptors; angiogenesis; prostaglandin E2; adenosine; chemotaxis; CAM; Chorioallantoic membrane; CBMC; Cord blood-derived mast cell; GAPDH; Glyceraldehyde-3-phosph
Antiinflammatory effects of Bu-zhong-yi-qi-tang in patients with perennial allergic rhinitis
Keywords: لوکوترین C4; Traditional Chinese medicine; Allergic rhinitis; Bu-zhong-yi-qi-tang; Immunoglobulin E; Prostaglandin E2; Leukotriene C4; Cyclooxygenase 2 mRNA
Diminished drug transport and augmented radiation sensitivity caused by loss of RLIP76
Keywords: لوکوترین C4; RLIP76 (RalBP1); Ral-interacting protein; GSH; glutathione; GS-E; glutathione-electrophile conjugates; DNP-SG; dinitrophenyl S-glutathione; COL; colchicine; DOX; doxorubicin; 4HNE; 4-hydroxynonenal; IOVs; inside-out vesicles; LTC4; leukotriene C4; MEFs;
Molecular cloning and functional characterization of cynomolgus monkey multidrug resistance-associated protein 2 (MRP2)
Keywords: لوکوترین C4; ABC; ATP-binding cassette; MRP; multidrug resistance-associated protein; CMV; canalicular membrane vesicles; E2-17βG; 17β-estradiol 17-(β-d-glucuronide); DNP-SG; 2,4-dinitrophenyl-S-glutathione; LTC4; leukotriene C4; ABC transporter; MRP2; Cynomolgus m
Role of proline 1150 in functional interactions between the membrane spanning domains and nucleotide binding domains of the MRP1 (ABCC1) transporter
Keywords: لوکوترین C4; MRP; multidrug resistance protein; ABC; ATP-binding cassette; MSD; membrane spanning domain; NBD; nucleotide binding domain; LTC4; leukotriene C4; E217βG; 17β-estradiol 17β-d-glucuronide; CL; cytoplasmic loop; MTX; methotrexate; HEK; human embryonic ki
Multidrug resistance protein 1 is not associated to detergent-resistant membranes
Keywords: لوکوترین C4; ABC; ATP-binding cassette; AMP; adenosine monophosphate; ATP; adenosine triphosphate; CFTR; cystic fibrosis transmembrane conductance regulator; CRAC; cholesterol recognition/interaction amino acid consensus; DRM; detergent-resistant membrane; HEK; human
Use of canalicular membrane vesicles (CMVs) from rats, dogs, monkeys and humans to assess drug transport across the canalicular membrane
Keywords: لوکوترین C4; Biliary clearance; Canalicular membrane vesicles; Cynmologus monkey; Dog; Drug transport; Estradiol-17β-d-glucuronide; Human; Leukotriene C4; Methods; Rat;
MRP1 mutated in the L0 region transports SN-38 but not leukotriene C4 or estradiol-17 (β-d-glucuronate)
Keywords: لوکوترین C4; ABC transporter; ATP-binding cassette transporter; ACNU; 3-[(4-amino-2-methyl-5-pyrimidinyl) methyl]-1-(2-chloroethyl)-1-nitrosourea; ADM; adriamycin; AG-A; agosterol A; azidoAG-A; [125I] 11-azidophenyl agosterol A; AZT; azidothymidine; BSO; buthionine su
Role of two adjacent cytoplasmic tyrosine residues in MRP1 (ABCC1) transport activity and sensitivity to sulfonylureas
Keywords: لوکوترین C4; ABC; ATP-binding cassette; MRP; multidrug resistance protein; BCRP; breast cancer resistance protein; LTC4; leukotriene C4; E217βG; 17β-estradiol-17-β-(d-glucuronide); NBD; nucleotide binding domain; MSD; membrane spanning domain; TM; transmembrane; CL
Limited modulation of the transport activity of the human multidrug resistance proteins MRP1, MRP2 and MRP3 by nicotine glucuronide metabolites
Keywords: لوکوترین C4; ABC; ATP-binding cassette; MRP; multidrug resistance protein; GSH; glutathione; MTX; methotrexate; LTC4; leukotriene C4; E217βG; 17β-estradiol 17β-(d-glucuronide); E13SO4; estrone 3-sulfate; NNAL; 4-(methylnitrosamino)1-(3-pyridyl)-1-butanol; DTT; dith
Nucleotide dissociation from NBD1 promotes solute transport by MRP1
Keywords: لوکوترین C4; P-gp; P-glycoprotein; MRP1; multidrug resistance-associated protein 1; NBD; nucleotide binding domain; LTC4; leukotriene C4; SDS; sodium dodecyl sulfate; EDTA; ethylenediaminetetraacetic acid; 8-N3ATP; 8-azidoadenosine 5â²-triphosphate; Sf21; Spodoptera
Cysteinyl Leukotrienes in Allergic Inflammation
Keywords: لوکوترین C4; asthma; cytokines; eosinophils; inflammation; leukotrienes; leukotriene receptor antagonists; remodeling; rhinitis; AR; allergic rhinitis; AUC; area under the FEV1-vs-time curve; CysLT; cysteinyl leukotriene; GM-CSF; granulocyte-macrophage colony-stimul