Keywords: کیناز کیناز B1; T2DM; Type 2 diabetes mellitus; NG; normal glucose concentration; HG; high glucose concentration; mTORC; mammalian target of rapamycin complex; GLUT; glucose transporters; LKB1; Liver kinase B1; AMPK; AMP-activated protein kinase; AKT; Protein kinase B; A
مقالات ISI کیناز کیناز B1 (ترجمه نشده)
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Keywords: کیناز کیناز B1; Methionine; Apoptosis; Lipid deposition; Lipid metabolism; Signaling pathway; AKT; RAC-alpha serine/threonine-protein kinase; AMPK; AMP-activated kinase; APO; Apolipoprotein; cAMP; Cyclic AMP; CPT-1; Carnitine palmitoyl transferase-1; CREBCyclic; AMP-resp
Keywords: کیناز کیناز B1; MS; mass-spectrometry; NMR; nuclear magnetic resonance spectroscopy; MRS; magnetic resonance spectroscopy; D-2-HG; D-2-hydroxyglutarate; α-KG; α-ketoglutarate; OAA; oxaloacetic acid; TET; ten-eleven translocation; GSH; glutathione; ROS; reactive oxygen
Keywords: کیناز کیناز B1; Sirt1; Sirtuin 1; SREBPs; Sterol regulatory element binding proteins; AMPK; AMP-activated protein kinase; ACC; Acetyl-CoA carboxylase; Fas; Fatty acid synthase; Nampt; Nicotinamide phosphoribosyltransferase; LKB1; Liver kinase B1; ER; Endoplasmic reticulu
Keywords: کیناز کیناز B1; â¢OH; hydroxyl radical; 2,2-BP; 2,2-bipyridyl; ABC; ATP-binding cassette; AIF; apoptosis-inducing factor; AMPK; AMP-activated protein kinase; AMPKK; AMPK kinase; ANT; adenine nucleotide translocase; AP-1; activator protein 1; Apaf-1; protease activating
Keywords: کیناز کیناز B1; AML; acute myeloid leukemia; BRCA; breast cancer; BRCC3; BRCA1/BRCA2-Containing Complex Subunit 3; C; constant; CLL; chronic lymphocytic leukemia; CML; chronic myeloid leukemia; CSC; cancer stem-like cell; EGFR; epidermal growth factor receptor; EMT; epit
Keywords: کیناز کیناز B1; 2-DG; 2-deoxyglucose; 2-HG; 2-hydroxyglutarate; 5mC; 5-methlycystosine; ACACA; acetyl-CoA carboxylase; AML; acute myeloid leukemia; AMPK; adenosine monophosphate-activated protein kinase; ATP; adenosine triphosphate; ALDH; aldehyde dehydrogenase; ADCs; an
Keywords: کیناز کیناز B1; CRP; C-reactive protein; HDL; high density lipoprotein; LDL; low density lipoprotein; PPARγ; peroxisome proliferator activated receptor-γ; DPP-4; dipeptidyl peptidase-4; GLP-1; glucagon like peptide-1; TRIB3; tribbles homolog 3; ATF-4; activating transc
Keywords: کیناز کیناز B1; ACC; acetyl CoA carboxylase; ALT; alanine aminotransferase; AMPK; 5' adenosine monophosphate-activated protein kinase; AST; aspartate transaminase; CRP; C-reactive protein; FAS; fatty acid synthase; HFD; high-fat diet; HMB; β-hydroxy-β-methyl-butyrate
Keywords: کیناز کیناز B1; ASCs; adipose stromal cells; CLS; crown-like structures; COX-2; cyclooxygenase-2; WAT; white adipose tissue; EP receptors; E prostanoid receptors; ER; estrogen receptor; IGF-I; insulin-like growth factor-I; NF-κB; nuclear factor kB; STAT3; signal transdu
Keywords: کیناز کیناز B1; ACLY; ATP citrate lyase; AKT; protein kinase B; ATP; adenosine triphosphate; ANT; adenine nucleotide translocator; AMPK; AMP-activated protein kinase; COX; cytochrome c oxidase; EGFR; epidermal growth factor receptor; ERRα; estrogen-related receptor alph
Keywords: کیناز کیناز B1; GLI1/2/3; glioma-associated oncogene homologue 1/2/3; PTCH; patched; SMO; smoothened; SUFU; suppressor of fused; CDO; CAM-related/downregulated by oncogenes; BOC; brother of CDO; GAS1; growth arrest-specific 1; PKA; protein kinase A; GSK3β; glycogen synt
Keywords: کیناز کیناز B1; ALDH2; aldehyde dehydrogenase 2; ANT; adenine nucleotide transportor; AR; aldose reductase; AMPK; AMP-activated protein kinase; ATF6; activating transcription factor 6; ATG; AuTophaGy; ATM; ataxia-telangiectasia mutate; COPD; chronic obstructive pulmonary
Keywords: کیناز کیناز B1; LKB1; liver kinase B1; AMPK; AMP-activated protein kinase; mTOR; mammalian target of rapamycin; ULK1/2; unc-51-like kinase1/2; FIP200; focal adhesion kinase family-interacting protein of 200Â kDa; PI; phosphatidylinositol; LC3; microtuble-associated prote
Liver kinase B1 induces browning phenotype in 3â¯T3-L1 adipocytes
Keywords: کیناز کیناز B1; LKB1; Liver kinase B1; WAT; white adipose tissue; BAT; brown adipose tissue; UCP1; uncoupling protein 1; AMPK; adenosine monophosphate-activated protein kinase; PPARγ; Peroxisome proliferator-activated receptor γ; PGC-1α; PPARγ coactivator-1α; PRDM16
Melanoma metabolism contributes to the cellular responses to MAPK/ERK pathway inhibitors
Keywords: کیناز کیناز B1; MAPK; mitogen-activated protein kinase; BRAF; v-raf murine sarcoma viral oncogene homolog B1; MEK; mitogen-activated protein/extracellular signal- regulated kinase kinase; ERK; extracellular signal-regulated kinase; HIF-1α; hypoxia inducible factor 1 alp
Gallotannin derivatives from mango (Mangifera indica L.) suppress adipogenesis and increase thermogenesis in 3T3-L1 adipocytes in part through the AMPK pathway
Keywords: کیناز کیناز B1; ATCC; American Type Culture Collection; AMPK; AMP-activated protein kinase; BAT; brown adipose tissue; C/EBPα; CCAAT/enhancer binding protein α; CPT1; carnitine palmitoyltransferase I; DCFH-DA; 2â²,7â²-dichlorofluorescein diacetate; DMEM; Dulbecco's
Exercise improves glucose uptake in murine myotubes through the AMPKα2-mediated induction of Sestrins
Keywords: کیناز کیناز B1; 2-NBDG; 2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2- Deoxyglucose; 3-MA; 3-Methyladenine; ACC; Acetyl-CoA Carboxylase; Ad; adenoviruses; AKT; Protein Kinase B, also known as AKT; AMPK; Adenosine 5â²-monophosphate (AMP)-activated protein kinase; AT
Vanadium(IV)-chlorodipicolinate alleviates hepatic lipid accumulation by inducing autophagy via the LKB1/AMPK signaling pathway in vitro and in vivo
Keywords: کیناز کیناز B1; 3-MA; 3-methyladenine; ALT; alanine aminotransferase; AMPK; adenosine monophosphate-activated protein kinase; AST; aspartate aminotransferase; BSOV; bis((5-hydroxy-4-oxo-4H-pyran-2-yl)methyl-2-hydroxy-benzoatato) oxovanadium (IV); DMEM; Dulbecco's modifie
Crystal structure of the kinase and UBA domains of SNRK reveals a distinct UBA binding mode in the AMPK family
Keywords: کیناز کیناز B1; SNRK; AMPK family; KD-UBA; Structural diversity; SNRK; sucrose non-fermenting (snf1)-related kinase; AMPK; AMP-activated protein kinase; BRSK; brain-specific kinase; MARK; microtubule affinity regulating kinase; SIK; salt-inducible kinase; NUAK; nuclear A
Differentially expressed novel alternatively spliced transcript variant of tumor suppressor Stk11 gene in mouse
Keywords: کیناز کیناز B1; STK11; Serine/threonine kinase 11; AMPK; Adenine monophosphate-activated protein kinase; Lkb1; Liver kinase b1; PJS; Peutz-Jeghers syndrome; STRAD; STe20-related adaptor protein; MO25; Mouse adaptor protein 25; NSCLC; Non-small cell lung cancer; IAEC; Ins
Tanshinone IIA suppresses FcεRI-mediated mast cell signaling and anaphylaxis by activation of the Sirt1/LKB1/AMPK pathway
Keywords: کیناز کیناز B1; ACC; acetyl-CoA carboxylase; Ac-Lys; acetylated lysine; AMPK; AMP-activated protein kinase; BMMCs; bone marrow-derived mast cells; HSA; human serum albumin; IKK; IκB kinase; IL-6; interleukin-6; JNK; c-Jun N-terminal kinase; LAT; linker for activation of
Balasubramide derivative 3C modulates microglia activation via CaMKKβ-dependent AMPK/PGC-1α pathway in neuroinflammatory conditions
Keywords: کیناز کیناز B1; AMPK; AMP-activated protein kinase; CaMKKβ; calcium/calmodulin-dependent protein kinase kinase beta; CBF; cerebral blood flow; CCA; common carotid artery; EBSS; glucose-free Earle's balanced salt solution; ECA; external carotid artery; ELISA; cytokine en
ERK1/2 activated PHLPP1 induces skeletal muscle ER stress through the inhibition of a novel substrate AMPK
Keywords: کیناز کیناز B1; 2-NBDG; 2-(N-[7-nitrobenz-2-oxa-1,3-diazol-4-yl]amino)-2-deoxyglucose; AICAR; 5-aminoimidazole-4-carboxamide-1-b-d-ribofuranoside; AMPK; AMP-activated protein kinase; AS160; Akt Substrate of 160â¯kDa; ATF4; Activating Transcription Factor 4; AUC; area un
The emerging role of AMP-activated protein kinase in cholestatic liver diseases
Keywords: کیناز کیناز B1; AMPK; AMP-activated protein kinase; PSC; primary sclerosing cholangitis; LKB1; Liver Kinase B1; CamKKβ; Ca2+-calmodulin-activated protein kinase beta; ERK1/2; extracellular signal-regulated kinase 1/2; FXR; farnesoid X receptor; BSEP; bile salt export pu
The impact of tau hyperphosphorylation at Ser262 on memory and learning after global brain ischaemia in a rat model of reversible cardiac arrest
Keywords: کیناز کیناز B1; Tau phosphorylation; Glycogen synthase Kinase-3β; Protein phosphatase 2A; Liver kinase B1; Adenosine monophosphate kinase protein kinase; Ischaemia/reperfusion;
Supplementation with Vitis vinifera L. skin extract improves insulin resistance and prevents hepatic lipid accumulation and steatosis in high-fat diet-fed mice
Keywords: کیناز کیناز B1; Grape skin, polyphenols; Hepatic steatosis; Insulin resistance, oxidative stress; ABCG5; ATP-biding cassette, subfamily G transporter 5; ABCG8; ATP-biding cassette, subfamily G transporter 8; ACH09; grape skin extract; AMPK; adenosine-monophosphate-acti
Sub-cellular localization specific SUMOylation in the heart
Keywords: کیناز کیناز B1; AMPK; adenosine monophosphate-activated protein kinase; CAMKK; calcium-calmodulin-activated protein kinase kinase; CHIP; carboxyl terminus of HSP70-interacting protein; CVD; cardiovascular disease; cTnI; cardiac troponin I; d-flow; disturbed flow; DeSI; d
Inhibitions of mTORC1 and 4EBP-1 are key events orchestrated by Rottlerin in SK-Mel-28 cell killing
Keywords: کیناز کیناز B1; Rottlerin; AMPK; mTOR; 4EBP-1; Autophagy; Protein synthesis; RPMI; Roswell Park Memorial Institute (RPMI); Becl-1; beclin-1; AMPK; AMP-activated protein kinase; ACC; acetyl-CoA carboxylase; mTOR; mammalian target of rapamycin; raptor; regulatory-associate
Lkb1 deletion upregulates Pax7 expression through activating Notch signaling pathway in myoblasts
Keywords: کیناز کیناز B1; AMPK; AMP-activated protein kinase; BAT; brown adipose tissue; DAPT; N-[N-(3,5-difluorophenacetyl-l-alanyl)]-S-phenylglycine t-butyl ester; FBS; fetal bovine serum; H&E; hematoxylin and eosin; Lkb1; Liver kinase B1; mTOR; mammalian target of rapamycin; N1
Recent progress in the identification of adenosine monophosphate-activated protein kinase (AMPK) activators
Keywords: کیناز کیناز B1; ACC; acetyl-CoA carboxylase; ADaM; allosteric drug and metabolite; AID; auto-inhibitory domain; α-RIM; α-regulatory interacting motif; AMPK; adenosine monophosphate-activated protein kinase; ASMS; affinity selection mass spectrometry; CamKKβ; Ca2+/calm
Hepatitis B virus (HBV) X protein-mediated regulation of hepatocyte metabolic pathways affects viral replication
Keywords: کیناز کیناز B1; HBV; Hepatitis B virus; HCC; Hepatocellular carcinoma; HBx; HBV X protein; cccDNA; Covalently closed circular DNA; ORF; Open reading frame; mTORC1; Mammalian target of rapamycin (mTOR) complex 1; TSC2; Tuberous-sclerosis complex-2; AMPK; AMP-activated pro
Rapamycin requires AMPK activity and p27 expression for promoting autophagy-dependent Tsc2-null cell survival
Keywords: کیناز کیناز B1; AMPK; 5â² AMP-activated protein kinase; Atg13; autophagy-related protein 13; CDK; cyclin-dependent kinase; DAPI; 4â²,6-diamidino-2-phenylindole; DMEM; Dulbecco's modified eagle's medium; DMSO; dimethyl sulfoxide; FDA; US Food and Drug Administration; GF
AMPK/Snf1 signaling regulates histone acetylation: Impact on gene expression and epigenetic functions
Keywords: کیناز کیناز B1; ACAT1; acetoacetyl-CoA thiolase; ACC; acetyl-CoA carboxylase; AICAR; 5-aminoimidazole-4-carboxamide ribonucleoside; AMPK; AMP-activated protein kinase; ATAC; Ada-two-A-containing; BET; bromodomains and extra-terminal motif; BMAL1; PAS domain-containing pr
Methylisoindigo preferentially kills cancer stem cells by interfering cell metabolism via inhibition of LKB1 and activation of AMPK in PDACs
Keywords: کیناز کیناز B1; Indirubin; Meisoindigo; Pancreatic cancer stem cell; CSC drug; LKB1 inactivation; AMPK activation; PDAC; CD133; 2-DG; 2-deoxyglucose; ACC; acetyl-CoA carboxylase; AMPK; 5â² AMP-activated protein kinase; CHK2; check point kinase 2; DM; Dorsomorphin; ESA;
Condensed catechins and their potential health-benefits
Keywords: کیناز کیناز B1; ACE; angiotensin I-converting enzyme; AMPK; AMP-activated protein kinase; AUC; area under the curve; BGL; blood glucose level; CaMKK; Ca2+/camodulin-dependent protein kinase kinase; COX; cyclooxygenases; EC; (â)-epicatechin; EDRF; endothelium derived-re
Activated AMPK boosts the Nrf2/HO-1 signaling axis-A role for the unfolded protein response
Keywords: کیناز کیناز B1; ACC; acetyl-CoA carboxylase; AMPK; AMP-activated kinase; ARE; antioxidant response element; βTrcP1; β-transducin-repeat containing protein 1; CaMKK; calcium calmodulin-dependent kinase kinase; CHO; Chinese hamster ovary; DCF; dichlorofluorescein; DMSO;
Honokiol activates the LKB1-AMPK signaling pathway and attenuates the lipid accumulation in hepatocytes
Keywords: کیناز کیناز B1; ACC; acetyl-CoA carboxylase; AMPK; AMP-activated protein kinase; ATGL; adipose triglyceride lipase; CaMKK; calcium/calmodulin-dependent protein kinase kinase; FAS; fatty acid synthase; FFA; free fatty acid; HFD; high fat diet; Hon; honokiol; LKB1; liver k
Integrative Genomic Analysis Reveals a High Frequency of LKB1 Genetic Alteration in Chinese Lung Adenocarcinomas
Keywords: کیناز کیناز B1; Liver kinase B1; Lung cancer; Multiplex ligation-dependent probe amplification;
Oxidative stress activates AMPK in cultured cells primarily by increasing cellular AMP and/or ADP
Keywords: کیناز کیناز B1; AMPK; AMP-activated protein kinase; CaMKK; calmodulin-dependent kinase kinase; GO; glucose oxidase; LKB1; liver kinase B1; AMP; ADP; AMP-activated protein kinase; Hydrogen peroxide; Oxidative stress;
Fluoxetine suppresses AMP-activated protein kinase signaling pathway to promote hepatic lipid accumulation in primary mouse hepatocytes
Keywords: کیناز کیناز B1; FLX; fluoxetine; SSRI; selective serotonin reuptake inhibitors; AMPK; AMP-activated protein kinase; LKB1; liver kinase B1; AICAR; 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside; Compound C; 6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo
Glabridin induces glucose uptake via the AMP-activated protein kinase pathway in muscle cells
Keywords: کیناز کیناز B1; ACC; acetyl CoA carboxylase; ACO; acyl CoA oxidase; AICAR; 5-amino-1-β-d-ribofuranosyl-imidazole-4-carboxamide; AMPK; adenosine monophosphate-activated protein kinase; AS160; Akt substrate 160 kDa; BSA; bovine serum albumin; CaMKII; Ca2+/calmodulin-depe
A high isoflavone diet decreases 5â² adenosine monophosphate-activated protein kinase activation and does not correct selenium-induced elevations in fasting blood glucose in mice
Keywords: کیناز کیناز B1; AMPK; Adenosine monophosphate-activated protein kinase; LKB1; Liver kinase B1; ACC; Acetyl-CoA carboxylase; Se; Selenium; GLUT4; Glucose transporter type 4; IR; Insulin resistance; Cyt C; Cytochrome c; UCP3; Uncoupling protein 3; SMSC; Se-methylselenocy
Cocoa flavonoids attenuate high glucose-induced insulin signalling blockade and modulate glucose uptake and production in human HepG2 cells
Keywords: کیناز کیناز B1; AKT/PKB; protein kinase B; AMPK; 5â²-AMP-activated protein kinase; BrdU; 5-bromo-2â²-deoxyuridine; CaMMK; Ca2+/calmodulin-dependent protein kinase kinase; CPE; cocoa phenolic extract; EC; (â)-epicatechin; EGCG; epigallocatechin gallate; ERK; extracell
Alpha-lipoic acid improves high-fat diet-induced hepatic steatosis by modulating the transcription factors SREBP-1, FoxO1 and Nrf2 via the SIRT1/LKB1/AMPK pathway
Keywords: کیناز کیناز B1; ACC; acetyl-CoA carboxylase; ALA; alpha-lipoic acid; ALT; alanine aminotransferase; AICAR; 5-aminoimidazole-4-carboxamide riboside; AMPK; AMP-activated protein kinase; AST; aspartate aminostransferase; ATGL; adipose triacylglycerol lipase; CaMKK; Ca2+/cal
AMPK-α1 functions downstream of oxidative stress to mediate neuronal atrophy in Huntington's disease
Keywords: کیناز کیناز B1; 3D; three-dimensional; ACC; acety-CoA carboxylase; AD; Alzheimer's disease; AICAR; aminoimidazole carboxamide riboside; AMPK; AMP-activated protein kinase; ALS; amyotrophic lateral sclerosis; ATM; ataxia telangiectasia mutated; CaMKII; Ca2Â +/calmodulin-d
New insights into Notch1 regulation of the PI3K-AKT-mTOR1 signaling axis: Targeted therapy of γ-secretase inhibitor resistant T-cell acute lymphoblastic leukemia
Keywords: کیناز کیناز B1; ADAM; a disintegrin and metalloprotease; AICAR; 5-aminoimidazole-4-carboxamide ribonucleotide; AKT; protein kinase B (PKB); ALL; acute lymphoblastic leukemia; AML; acute myeloid leukemia; AMPK; adenosine monophosphate (AMP) activated protein kinase; ANK;
Research ReportOver-expression of the Sirt3 sirtuin Protects neuronally differentiated PC12 Cells from degeneration induced by oxidative stress and trophic withdrawal
Keywords: کیناز کیناز B1; AMPK; AMP-activated protein kinase; AU; arbitrary units; GD; glucose deprivation; GFP; green fluorescent protein; HEK293; human embryonic kidney 293 cell line; LKB1; liver kinase B1; NGF; nerve growth factor; OGD; oxygen-glucose deprivation; PBS; phosph
mTOR signaling in tumorigenesis
Keywords: کیناز کیناز B1; mTOR; the mechanistic target of rapamycin or the mammalian target of rapamycin; PIKK; phosphoinositide 3-kinase related protein kinase; ATM; ataxia-telangiectasia mutated; ATR; ataxia-telangiectasia and rad3-related; DNAPK; DNA-dependent protein kinase; R
Molecular targets for cancer therapy in the PI3K/AKT/mTOR pathway
Keywords: کیناز کیناز B1; PI3K pathway; Targeted therapy; Predictive biomarkers; 4EBP1; 4E-binding protein 1; AKT; protein kinase-B; AMPK; AMP-activated protein kinase; COSMIC; Catalogue of Somatic Mutations in Cancer; eIF4E; eukaryotic initiation factor 4E; ERK; extracellular-sig