Keywords: محدودیت پایین تشخیص; Allergen; indoor; exposure; home; allergy; LLOD; Lower limit of detection; MARIA; Multiplex Array for Indoor Allergens; NCHS; National Center for Health Statistics; NHANES; National Health and Nutrition Examination Survey; NSLAH; National Survey of Lead a
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Keywords: محدودیت پایین تشخیص; Peanut; peanut foods; peanut butter; peanut flour; peanut allergens; oral immunotherapy; allergen dosing; risk assessment; allergen standardization; LLOD; Lower limit of detection; NIST SRM 2387; National Institute for Standards and Technology Peanut Butt
Keywords: محدودیت پایین تشخیص; CV; coefficient of variation; DHT; dihydrotestosterone; DHEA; dehydroepiandrosterone; GC-MS/MS; gas chromatography-tandem mass spectrometry; LC-MS; liquid chromatography-mass spectrometry; LOD; lower limit of detection; LOQ; lower limit of quantif
Keywords: محدودیت پایین تشخیص; BAFF; B-cell activating factor; BMI; body mass index; CI; confidence interval; CCL11; C-C motif ligand 11; CV; coefficient of variation; CXCL8; C-X-C motif ligand 8; GM-CSF; granulocytemacrophage colony-stimulating factor; HCV; hepatitis C virus; HIV; hum
Keywords: محدودیت پایین تشخیص; DWTP; drinking water treatment plant; FIB; fecal indicator bacteria; LLOD; lower limit of detection; MPN; most probable number; MST; microbial source tracking; WHO; World Health Organization; Escherichia coli; Bacteroides; Fecal coliforms; Regrowth; Post
Keywords: محدودیت پایین تشخیص; D/P system; dissolution/permeation system; DSC; differential scanning calorimetry; FaSSIF; fasted state simulated intestinal fluid; HCS; hydrocortisone; IS; internal standard; Jss; steady-state flux; LLOD; lower limit of detection; LLOQ; lower limit of qu
Keywords: محدودیت پایین تشخیص; Thyroid hormone metabolites; Tandem mass spectrometry; 3-Iodothyronamine; Iodothyronine; CLIA; Chemiluminescence immunoassays; 3,5-T2; 3,5-Diiodo-L-thyronine; 3,3â²-T2; 3,3'-Diiodo-L-thyronine; ELISA; Enzyme-linked immunosorbent assay; FDA; Food and Dr
Keywords: محدودیت پایین تشخیص; AA; Ascorbic Acid; Ab; Antibody; AFM; Atomic Force Microscopy; AFP; α-Fetoprotein; AgNPs; Silver Nanoparticles; APTES; 3-Aminopropyltriethoxysilane; AuNCs; Gold Nanocubes; AuNPs; Gold Nanoparticles; BN; Boron Nitride; BNS; Boron Nitride Nanosheets; BSA;
Keywords: محدودیت پایین تشخیص; EL; electroless; TMB-HCL; 3,3â²,5,5â²-tetramethylbenzidine dihydrochloride; NBS; N-bromosuccinimide; TFA; trifluoroacetic acid; ICP-OES; inductively coupled plasma optical emission spectrometry; SERS; surface enhanced Raman spectroscopy; LOQ; lower limi
Keywords: محدودیت پایین تشخیص; BiP; binding of immunoglobulin protein; BMI; body mass index; CHOP; CCAAT/enhancer-binding protein homologous protein; C-peptide; insulin connecting peptide; ER; endoplasmic reticulum; FPIR; first phase insulin response; GAD65; glutamic acid decarboxylase
Keywords: محدودیت پایین تشخیص; DCX; docetaxel; PK; phamacokinetic; PD; pharmacodynamic; HPLC; high-performance liquid chromatography; UV; ultraviolet; MS/MS; tandem mass spectrometry; UPLC; ultra-performance liquid chromatography; MTBE; methyl t-butyl ether; LC; liquid chromatography;
Keywords: محدودیت پایین تشخیص; Neonatal pertussis; Antibody transfer; Pregnancy; Vaccination; CDC; Centers for Disease Control and Prevention; CI; confidence interval; DTaP; diphtheria, tetanus and high antigenic load of acellular pertussis vaccine; DTwP; diphtheria, tetanus and whole-
Keywords: محدودیت پایین تشخیص; 6-MAM; 6-monoacetylmorphine; AAFS; American Academy of Forensic Sciences; APCI; atmospheric pressure chemical ionization; API; atmospheric pressure ionization; CAP; College of American Pathologists; CI; chemical ionization; CLSI; Clinical and Laboratory S
Keywords: محدودیت پایین تشخیص; ELSD; evaporative light scatter detector; NSAID; non-steroidal anti-inflammatory drug; HPTS; 8-hydroxypyrene-1,3,6-trisulfonate; 4,4'oBBV; 1,1'-bis(2-boronobenzyl)-4,4'-bipyridinium; 4,4'oMBV; 1-benzyl-1'-(2-boronobenzyl)-4,4'-bipyridinium, CV
Keywords: محدودیت پایین تشخیص; Bacillus anthracis; Anthrax; Anthrax Vaccine Adsorbed; AVA; Biothrax; Correlates of protection; Clinical trial; Non-clinical trial; Animal model; AE; adverse events; AUC; area under the receiving operator characteristic curve; AVA; Anthrax Vaccine Adsorbe
Keywords: محدودیت پایین تشخیص; DBS; dried blood spot; LC-MS/MS; liquid chromatography/tandem mass spectrometry; MRM; multiple reaction monitoring; ROP; retinopathy of prematurity; β-ARs; pharmacological blockade of beta-adrenoreceptors; HPLC; high-performance liquid chromatography;
Keywords: محدودیت پایین تشخیص; MARIA; multiplex array for indoor allergens; ELISA; enzyme-linked immunosorbent assay; CV; coefficient of variation; CCC; concordance correlation coefficient; LLOD; lower limit of detection; PBS; phosphate buffered saline; NAEPP; National Asthma Education
Quantitative determination of cyclic phosphatidic acid and its carba analog in mouse organs and plasma using LC-MS/MS
Keywords: محدودیت پایین تشخیص; 2ccPA; 2-carba-cyclic phosphatidic acid; ATX; autotaxin; BSA; bovine serum albumin; CID; collision-induced dissociation; CNS; central nervous system; cPA; cyclic phosphatidic acid; CV; coefficient of variation; EDTA-Na2; ethylenediaminetetraacetic acid di
Plasma pharmacokinetics and cerebral nuclei distribution of major constituents of Psoraleae fructus in rats after oral administration
Keywords: محدودیت پایین تشخیص; Psoraleae fructus; Pharmacokinetics; Cerebral nuclei distribution; Coumarins; Prenylflavonoids; LC-MS/MS; ACN; acetonitrile; AUC; area under curve; Aβ42; β-amyloid 42; CE; collision energy; Cmax; maximum drug concentration; CMC-Na; carboxymethyl cellulo
Cellulose-based amorphous solid dispersions enhance rifapentine delivery characteristics in vitro
Keywords: محدودیت پایین تشخیص; Rifapentine (PubChem CID: 6323497); Rifampicin (PubChem CID: 5458213); 3-Formylrifamycin (PubChem CID: 6438444); Hydroxypropylmethylcellulose acetate succinate (PubChem CID: 121950); ASD; amorphous solid dispersion; AUC; area under the curve; CASub; cellu
Description of analytical method and clinical utility of measuring serum 7-alpha-hydroxy-4-cholesten-3-one (7aC4) by mass spectrometry
Keywords: محدودیت پایین تشخیص; BAD; bile acid diarrhea; 7aC4; 7-alpha-hydroxy-4-cholesten-3-one; CV; coefficient of variation; IBS; irritable bowel syndrome; LC-MS/MS; liquid chromatography, tandem mass spectrometry; LLOD; lower limit of detection; LLOQ; lower limit of quantitation; 75
Evaluation of the accuracy of exchangeable copper and relative exchangeable copper (REC) in a mouse model of Wilson's disease
Keywords: محدودیت پایین تشخیص; WD; Wilson's disease; IHCu; intrahepatic copper; CuEXC; exchangeable copper; REC; relative exchangeable copper; Cus; total serum copper; LEC; Long-Evans Cinnamon; WT; wild type; ALT; serum alanine aminotransferase; AST; serum aspartate aminotransferase;
Pre-clinical and translational pharmacology of a human interleukin-22 IgG fusion protein for potential treatment of infectious or inflammatory diseases
Keywords: محدودیت پایین تشخیص; AUClast; Area under concentration-time curve; CL; Total clearance; COLO205; Intestinal epithelial cells; Cmax; Maximal serum concentration; DC; Dendritic Cells; DMEM; Dulbecco's modified Eagle's medium; DSS; Dextran sulfate sodium salt; EC50; Half max
Determination of edoxaban equivalent concentrations in human plasma by an automated anti-factor Xa chromogenic assay
Keywords: محدودیت پایین تشخیص; AE; Adverse events; aPTT; activated partial thromboplastin time; ANOVA; Analysis of variance; CI; Confidence interval; DOACs; Direct oral anticoagulants; FDA; Food and Drug Administration; FXa; Factor Xa; GLSM; Geometric least squares means; LC/MS/MS; Liq
Immune responses in DAA treated chronic hepatitis C patients with and without prior RG-101 dosing
Keywords: محدودیت پایین تشخیص; Chronic hepatitis C; DAA treatment; Immune response; miRNA-122; HCV; hepatitis C virus; IP-10; interferon gamma-induced protein; CHC; chronic hepatitis C; DAAs; direct acting antivirals; SVR; sustained virological response; miR-122; microRNA-122; RAS; res
Case reportLongitudinal monitoring of ctDNA EGFR mutation burden from urine correlates with patient response to EGFR TKIs: A case series
Keywords: محدودیت پایین تشخیص; ctDNA; circulating tumor DNA; LLoD; lower limit of detection; EGFR; Epidermal growth factor receptor; PCR; polymerase chain reaction; TKI; tyrosine kinase inhibitor; GEq; genome equivalent; CT; computerized tomography; q.d.; daily; MRI; magnetic response
Clinical development of a VAR2CSA-based placental malaria vaccine PAMVAC: Quantifying vaccine antigen-specific memory B & T cell activity in Beninese primigravidae
Keywords: محدودیت پایین تشخیص; ANV; antenatal visit; BD; Becton Dickinson; AEC; (3-amino-9-ethylcarbazole); CBA; cytometric bead array; CERPAGE; Centre d'Etude et de Recherche sur le Paludisme Associé à la Grossesse et à l'Enfance; CPDA; citrate phosphate dextrose adenine; IRD;
Memory B cell response to a PCV-13 booster in 3.5Â year old children primed with either PCV-7 or PCV-13
Keywords: محدودیت پایین تشخیص; ASC; antibody secreting cells; BCR; B cell receptor; BMEM; memory B cells; GC; germinal centre; LLD; lower limit of detection; MenC; group C meningococcus; OPA; opsonophagocytic activity; PBMCs; peripheral blood mononuclear cells; PBS; phosphate buffered
Autoantibodies of IgM and IgG classes show differences in recognition of multiple autoantigens in chronic obstructive pulmonary disease
Keywords: محدودیت پایین تشخیص; Aab; autoantibody; COPD; chronic obstructive pulmonary disease; FEV1%; forced expiratory volume in 1Â s as % of predicted; FVC; forced vital capacity; Hib; Haemophilus influenza b; LLoD; lower limit of detection; PBST; phosphate-buffered saline containing
A simple dilute and shoot approach incorporated with pentafluorophenyl (PFP) column based LC-MS/MS assay for the simultaneous determination of trimethylamine N-oxide and trimethylamine in spot urine samples with high throughput
Keywords: محدودیت پایین تشخیص; PFP; pentafluorophenyl; TMAO; trimethylamine N-oxide; TMA; trimethylamine; FMO3; flavin-containing monooxygenase 3; TMAU; trimethylaminuria; 1H NMR; proton nuclear magnetic resonance spectrometry; GC; gas chromatography; MS; mass spectrometer; LC; liquid
Detection and quantification of HIV-1 RNA with a fully automated transcription-mediated-amplification assay
Keywords: محدودیت پایین تشخیص; HIV RNA quantification; Lower limit of detection; Aptima HIV Quant Dx assay; Roche CAP/CTM HIV-1 version 2.0;
Simple and validated UHPLC-MS/MS analysis of nimodipine in plasma and cerebrospinal fluid of patients with subarachnoid haemorrhage
Keywords: محدودیت پایین تشخیص; NIM; nimodipine; LCS; lacosamide; I.S.; internal standard; SAH; aneurysmal subarachnoid haemorrhage; UHPLC; MS/MS ultra high performance liquid chromatography-tandem mass spectrometry; LLE; liquid-liquid extraction; CSF; cerebrospinal fluid; aCSF; artific
A new real-time RT-qPCR assay for the detection, subtyping and quantification of human respiratory syncytial viruses positive- and negative-sense RNAs
Keywords: محدودیت پایین تشخیص; 6-FAM; 6-carboxyfluorescein; BHQ; black hole quencher; CT; threshold cycle; hMPV; human metapneumovirus; hPIV; human parainfluenza virus; L-LOD; lower limit of detection; LNA; locked nucleic acid; MGB-NFQ; minor-groove binder non-fluorescence quencher; QC
The development and application of a high-sensitivity immunoassay for cardiac myosin-binding protein C
Keywords: محدودیت پایین تشخیص; ACS; acute coronary syndrome; AMI; acute myocardial infarction; cMyC; cardiac myosin-binding protein C; cTn; cardiac troponin; CV; coefficient of variation; DE; detected event; LoB; limit of blank; LoD; lower limit of detection; LLoQ; lower limit of qua
An improved micro-method for the measurement of steroid profiles by APPI-LC-MS/MS and its use in assessing diurnal effects on steroid concentrations and optimizing the diagnosis and treatment of adrenal insufficiency and CAH
Keywords: محدودیت پایین تشخیص; DHEA; dehydroepiandrosterone; DHT; dihydrotestosterone; 17 OHP; 17α-hydroxyprogesterone; 21-OHD; 21-hydroxylase deficiency; CAH; ongenital adrenal hyperplasia; HSD; 3α-hydroxysteroid dehydrogenase; LC-MS/MS; liquid chromatography-tandem mass spectro
An UPLC-MS/MS method coupled with automated on-line SPE for quantification of tacrolimus in peripheral blood mononuclear cells
Keywords: محدودیت پایین تشخیص; TAC; tacrolimus; TDM; therapeutic drug monitoring; MS; mass; MS/MS; tandem mass; UPLC; ultra performance liquid chromatography; HPLC; high performance liquid chromatography; LC; liquid; ESI+; positive electrospray ionization; PBMC; peripheral blood mononu
Research ArticleOmbitasvir/paritaprevir/r and dasabuvir plus ribavirin in HCV genotype 1-infected patients on methadone or buprenorphine
Keywords: محدودیت پایین تشخیص; HCV; hepatitis C virus; CYP3A4; cytochrome P450 isoform 3A4; RNA; ribonucleic acid; HIV; human immunodeficiency virus; LLOD; lower limit of detection; LLOQ; lower limit of quantitation; MedDRA; Medical Dictionary for Regulatory Activities; MEMS; Medicatio
Clinical and serum-based markers are associated with death within 1 year of de novo implant in primary prevention ICD recipients
Keywords: محدودیت پایین تشخیص; AUC; area under the curve; BNP; brain natriuretic peptide; CI; confidence interval; CK-MB; creatine kinase MB; CRP; C-reactive protein; cTnI; cardiac troponin I; cTnT; cardiac troponin T; CV; coefficient of variation; eGFR; estimated glomerular filtration
Evaluation of a chromogenic commercial assay using VWF-73 peptide for ADAMTS13 activity measurement
Keywords: محدودیت پایین تشخیص; ADAMTS13; A disintegrin and metalloprotease with thrombospondin type 1 repeats, member 13; CV; Coefficient of variation; FRETS-VWF73; Fluorescence resonance energy transfer-VWF73; HELLP; Hemolysis elevated liver enzymes low platelet count; HUS; Hemolytic
Hepatitis B virus DNA quantification with the three-in-one (3io) method allows accurate single-step differentiation of total HBV DNA and cccDNA in biopsy-size liver samples
Keywords: محدودیت پایین تشخیص; ALT; alanine transaminase; cccDNA; covalently closed circular DNA; FFPE tissue; formalin-fixed, paraffin-embedded tissue; gDNA; genomic DNA; hACTB; human β-actin gene; HBeAg; hepatitis B e antigen; HBsAg; hepatits B surface antigen; HBV; hepatitis B viru
HCV RNA detection in HCV antibody-positive patients with the COBAS® AmpliPrep/COBAS® TaqMan® HCV test, v2.0 in comparison with FDA-approved nucleic acid tests
Keywords: محدودیت پایین تشخیص; CHC; chronic HCV infection; DAA; direct acting antiviral; HCV; hepatitis C virus; LLOD; lower limit of detection; LOD; limit of detection; NPA; negative percent agreement; PCR; polymerase chain reaction; PPA; positive percent agreement; RGT; response guid
Emergence of resistance-associated variants after failed triple therapy with vaniprevir in treatment-experienced non-cirrhotic patients with hepatitis C-genotype 1 infection: A population and clonal analysis
Keywords: محدودیت پایین تشخیص; DAA; directly acting antiviral agent; HCV; hepatitis C virus; IC50; inhibitory concentration 50%; IU/mL; international units per milliliter; LLD; lower limit of detection; LLQ; lower limit of quantification; P/R; peginterferon alfa/ribavirin; SVR; sustain
Research ArticleLimited impact of IL28B genotype on response rates in telaprevir-treated patients with prior treatment failure
Keywords: محدودیت پایین تشخیص; DAA; direct-acting antiviral; HBV; hepatitis B virus; HCV; hepatitis C virus; HIV; human immunodeficiency virus; LLOD; lower limit of detection; LLOQ; lower limit of quantification; NS3; non-structural protein 3; OR; odds ratio; PCR; polymerase chain reac
G protein-coupled receptor quantification using peptide group-specific enrichment combined with internal peptide standard reporter calibration
Keywords: محدودیت پایین تشخیص; 5-HT; 5-hydroxytryptamine (serotonin); ESI; electrospray ionization; GPCR; G-protein coupled receptor; IPA; isopropyl alcohol; iTRAQ®; isobaric tag for relative and absolute quantification; LC-MS; liquid chromatography-mass spectrometry; LLOD; lower
Enhancing selectivity in spectrofluorimetric determination of tryptophan by using graphene oxide nanosheets
Keywords: محدودیت پایین تشخیص; GO; graphene oxide; Trp; l-tryptophan; Asn; l-asparagine; His; l-histidine; Phe; l-phenylalanine; Arg; l-arginine; Tyr; l-tyrosine; Lys; l-lysine; FD; formaldehyde; THCAs; 1,2,3,4-tetrahydro-β-carboline-3-carboxylic acids; LOD; lower limit of detection;
A fast, sensitive, and high throughput method for the determination of cefuroxime lysine in dog plasma by UPLC-MS/MS
Keywords: محدودیت پایین تشخیص; UPLC-ESI-MS/MS; ultra-performance liquid chromatography-electrospray ionization tandem mass spectrometric; PPT; protein precipitation; LLE; liquid-liquid extraction; MRM; multiple reaction monitoring; ESI; electrospray ionization; LLOQ; lower limi
Optimization and qualification of a multiplex bead array to assess cytokine and chemokine production by vaccine-specific cells
Keywords: محدودیت پایین تشخیص; 5PL; Five parameter log-logistic curve; HVTN; HIV Vaccine Trials Network; ICS; intracellular cytokine staining; LLOD; lower limit of detection; LOD; limit of detection; LOQ; limit of quantitation; MBA; multiplex bead array; PTE; potential T-cell epitope;
New Virologic Tools for Management of Chronic Hepatitis B and C
Keywords: محدودیت پایین تشخیص; Diagnostic Assay; Real-Time Polymerase Chain Reaction; Real-Time Transcription-Mediated Amplification; Next-Generation Sequencing; Antigen Quantification; Point-of-Care Tests; ALT; alanine aminotransferase; bp; base pair; DAA; direct-acting antiviral; DBS
A novel approach for long-term oral drug administration in animal research
Keywords: محدودیت پایین تشخیص; %RSD; % relative standard deviation; ESI; electrospray ionization; LLOD; lower limit of detection; LLOQ; lower limit of quantification; MRM; multiple reaction monitoring; QCs; quality controls; Anastrozole; Hydration gel; Liquid chromatography-mass spec
Correlation between Serum Caffeine Levels and Changes in Cytokine Profile in a Cohort of Preterm Infants
Keywords: محدودیت پایین تشخیص; AR; Adenosine receptor; BPD; Bronchopulmonary dysplasia; BUN; Blood urea nitrogen; cAMP; Cyclic adenosine monophosphate; CBC; Complete blood count; ETT; Endotracheal tube; GA; Gestational age; GM-CSF; Granulocyte and macrophage-colony stimulating factor;