Esculentoside A inhibits LPS-induced BV2 microglia activation through activating PPAR-γ
Keywords: Esculentoside A; LPS; Inflammatory response; PPAR-γ;
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Piperine attenuates lipopolysaccharide (LPS)-induced inflammatory responses in BV2 microglia
Keywords: Piperine; LPS; Inflammatory mediators; NF-κB; Nrf2;
Ozone exposure effect on systemic prostaglandin F2α in rat plasma and urine may not reveal pulmonary damage through inflammation
Keywords: PGF2α; prostaglandin F2α; 8-iso-PGF2α; 8-iso-prostaglandin F2α; CCL4; carbon tetrachloride; LPS; lipopolysaccharide; ROS; reactive oxygen species; TXB2; thromboxane B2; COPD; chronic obstructive pulmonary disease; Ozone; Prostaglandins; Cyclooxygenase
Muscle-specific deletion of SOCS3 does not reduce the anabolic response to leucine in a mouse model of acute inflammation
Keywords: SOCS3-MKO; SOCS3 muscle-specific knockout; LPS; lipopolysaccharide; SOCS3; Inflammation; Anabolic signaling; Protein synthesis;
Vitamin A differentially regulates cytokine expression in respiratory epithelial and macrophage cell lines
Keywords: LETs; respiratory tract epithelial cell line LET1; MACs; macrophage cell line MAC INF429; SeV; Sendai virus; LPS; lipopolysaccharide; RA; retinoic acid; RAR; retinoic acid receptor; RXR; retinoid X receptor; RARE; retinoic acid response element; Vitamin A
Platycodin D suppressed LPS-induced inflammatory response by activating LXRα in LPS-stimulated primary bovine mammary epithelial cells
Keywords: Platycodin D; BMEC; LPS; LXRα; NF-κB;
Corynoline attenuates LPS-induced acute lung injury in mice by activating Nrf2
Keywords: Corynoline; LPS; Lung injury; Nrf2;
Induction of heme oxygenas-1 attenuates NLRP3 inflammasome activation in lipopolysaccharide-induced mastitis in mice
Keywords: Mastitis; LPS; NLRP3 inflammasome; TXNIP; HO-1;
Asiatic acid inhibits LPS-induced inflammatory response in human gingival fibroblasts
Keywords: Asiatic acid; Human gingival fibroblasts; LPS; PPAR-γ;
Mangiferin inhibits mastitis induced by LPS via suppressing NF-ĸB and NLRP3 signaling pathways
Keywords: Mangiferin; LPS; Mastitis; NLRP3;
Characterization of the changes in eicosanoid profiles of activated macrophages treated with 20(S)-ginsenoside Rg3
Keywords: LPS; lipopolysaccharide; Rg3; 20(S)-ginsenoside Rg3; UPLC; ultra performance liquid chromatography; MS; mass spectrometry; PG; prostaglandin; LT; leukotriene; COX-2; cyclooxygenase-2; ELISA; enzyme-linked immunosorbent assays; NO; nitric oxide; TNF-α; tu
Fetal DNA does not induce preeclampsia-like symptoms when delivered in late pregnancy in the mouse
Keywords: Preeclampsia; Cell-free DNA; Fetal hypotrophy; Fetal nucleic acid; Pregnancy complication; GD; gestation day; LPS; lipopolysaccharide; TLR9; toll-like receptor 9;
Polysaccharides isolated from Hedyotis diffusa inhibits the aggressive phenotypes of laryngeal squamous carcinoma cells via inhibition of Bcl-2, MMP-2, and μPA
Keywords: HDP; Hedyotis diffusa polysaccharides; SCC; Squamous cell carcinoma; TCM; traditional Chinese medicine; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide; LPS; lipopolysaccharide; BSA; bovine serum albumin; DMSO; dimethyl sulfoxide; FB
Roles of alternatively activated M2 macrophages in allergic contact dermatitis
Keywords: Contact hypersensitivity; mannose receptor; MMP12; M2 macrophages; SOCS3; BM; bone marrow; CHS; contact hypersensitivity; DNFB; 2,4-dinitrofluorobenzene; GO; Gene Ontology; LPS; lipopolysaccharide; MerTK; Mer receptor tyrosine kinase; MMP12; matrix metall
Esculentoside A inhibits LPS-induced acute kidney injury by activating PPAR-γ
Keywords: Acute kidney injury; Esculentoside A; LPS; NF-κB; PPAR-γ;
Resveratrol inhibits LPS-induced mice mastitis through attenuating the MAPK and NF-κB signaling pathway
Keywords: Mastitis; Resveratrol; LPS; MAPK pathway;
Activation of neonatal microglia can be influenced by other neural cells
Keywords: P; postnatal day; LPS; lipopolysaccharide; IL-1β; interleukin-1β; IL-6; interleukin-6; TLR-4; Toll-like receptor 4; CD11b/c; cluster differentiation factor 11b/c; E. coli; Escherichia coli; DPBS; Dulbecco's phosphate buffered saline; qPCR; quantitativ
Research paperProfiling of cytosolic and mitochondrial H2O2 production using the H2O2-sensitive protein HyPer in LPS-induced microglia cells
Keywords: DPI; diphenyleneiodonium; ERK; extracellular signal-regulated kinases; JNK; c-Jun N-terminal kinases; LPS; lipopolysaccharide; NAC; N-acetyl-l-cysteine; NADPH oxidase; nicotinamide adenine dinucleotide phosphate oxidase; p38 MAPK; p38 mitogen-activated pr
In vivo and in vitro anti-sepsis effects of physcion 8-O-β-glucopyranoside extracted from Rumex japonicus
Keywords: Anti-sepsis; TLR-4; TLR-2; Pro-inflammatory cytokines; LPS;
Differential regulation of IL-23 production in M1 macrophages by TIR8/SIGIRR through TLR4- or TLR7/8-mediated signaling
Keywords: Granulocyte-macrophage colony-stimulating factor; IL-12p40; IL-23; Interferon regulatory factor 5; Single immunoglobulin interleukin-1 receptor-related molecule; ELISA; enzyme-linked immunosorbent assay; GMâCSF; granulocytemacrophage colony-stimulatin
C1q/TNF-related protein-3 exerts the chondroprotective effects in IL-1β-treated SW1353 cells by regulating the FGFR1 signaling
Keywords: OA; osteoarthritis; CTRP3; C1q/TNF-related protein-3; LPS; lipopolysaccharide; FGFs; fibroblast growth factors; EPCs; endothelial progenitor cells; SDF-1α; stromal cell-derived factor 1α; FGF-2; fibroblast growth factor-2; FGFR1; fibroblast growth facto
Synthesis and cytotoxic effects of (E)-3-(2,3-dimethoxyphenyl)-1-(5-methylfuran-2-yl) prop-2-en-1-one in MDA-MB231 and MCF-7 breast cancer cell lines
Keywords: ANOVA; one-way analysis of variance; DMMF; (E)-3-(2,3-dimethoxyphenyl)-1-(5-methylfuran-2-yl) prop-2-en-1-one; FTIR; Fourier transform infrared spectroscopy; IARC; International Agency for Research; IC50; half-maximal inhibition concentration; IFN-γ; Int
Original articleThe effects of desipramine, fluoxetine, or tianeptine on changes in bulbar BDNF levels induced by chronic social instability stress and inflammation
Keywords: Antidepressants; BDNF; Chronic social stress; LPS; Olfactory bulbs;
The common genetic variants in IL-1Î and IL-1RN may have no predisposition to alcoholic liver disease: A meta-analysis
Keywords: ALD; alcoholic liver disease; AWLD; alcoholics without liver disease; ALC; alcoholic liver cirrhosis; CD14; cluster of differentiation 14; CIs; confidence intervals; HCs; healthy controls; IL-1β; interleukin-1β; IL1-Ra; interleukin-1 receptor antagonist
Overexpression of MicA induces production of OmpC-enriched outer membrane vesicles that protect against Salmonella challenge
Keywords: Outer membrane vesicles; MicA; Salmonella; Immunity; Vaccine; OMV; outer membrane vesicle; OMP; outer membrane protein; sRNA; small RNA; LPS; lipopolysaccharide; IP; intraperitoneal; CFU; colony forming units; p.o; per os;
Deubiquitinase USP12 promotes LPS induced macrophage responses through inhibition of IκBα
Keywords: USP12; LPS; Macrophages; Inflammation; CYLD; Cylindromatosis; DUBA; deubiquitinating enzyme A; iNOS; inducible nitric oxide synthase; PTMs; Post translational modifications; TRAF3; TNF receptor associated factor 3; TRAF6; TNF receptor associated factor 6;
Alleviation of lipopolysaccharide/d-galactosamine-induced liver injury in leukocyte cell-derived chemotaxin 2 deficient mice
Keywords: LECT2; leukocyte cell-derived chemotaxin 2; LPS; lipopolysaccharide; d-GalN; d-galactosamine; GPT; glutamic pyruvic transaminase; MNC; mononuclear cell; Leukocyte cell-derived chemotaxin 2; LPS/d-GalN-induced liver injury; Interferon-γ;
Exposure to Porphyromonas gingivalis LPS during macrophage polarisation leads to diminished inflammatory cytokine production
Keywords: Macrophage; Porphyromonas gingivalis; Periodontitis; Cytokine; LPS;
Identification and functional characterization of a novel member of low-density lipoprotein receptor-related protein (LRP)-like family in amphioxus
Keywords: BSA; bovine serum albumin; CRD; carbohydrate-recognition domain; DNA; deoxyribonucleic acid; DTT; dithiothreitol; EDTA; ethylenediaminetetraacetic acid; h; hour; HRP; horseradish peroxidase; IPTG; isopropyl β-d-thiogalactoside; KDa; kilodalton(s); LB; Lu
Quinacrine Suppresses Tumor Necrosis Factor-α and IFN-α in Dermatomyositis and Cutaneous Lupus Erythematosus
Keywords: CLE; cutaneous lupus erythematosus; CpG; cytosine phosphodiester guanine; CQ; chloroquine; DM; dermatomyositis; HCQ; hydroxychloroquine; LPS; lipopolysaccharide; mDC; myeloid dendritic cell; MFI; mean fluorescence intensity; PBMC; peripheral blood mononuc
Immunomodulatory effect of APS and PSP is mediated by Ca2+-cAMP and TLR4/NF-κB signaling pathway in macrophage
Keywords: APS; astragalus polysaccharides; PSP; polysaccharopeptide; TLR4; toll like receptors 4; NF-κB; nuclear factor-κB; LPS; lipopolysaccharide; cAMP; cyclic adenosine monophosphate; DAG; diacylglycerol; IP3; inositol 1, 4, 5-triphosphate; PKC; protein kinase
Anti-CD24 neutralizing antibody exacerbates Concanavalin A-induced acute liver injury in mice via liver M1 macrophages
Keywords: Con A; concanavalin A; TNF-α; tumor necrosis factor alpha; LPS; lipopolysaccharide; M1; classically activated macrophage; M2; alternatively activated macrophage; CD24; Concanavalin A (Con A); Acute liver injury; Liver M1 macrophage; TNF-α;
Research articleKrüppel-like factor 4 regulates amyloid-β (Aβ)-induced neuroinflammation in Alzheimer's disease
Keywords: AD; Alzheimer's disease; Aβ; amyloid-β; Klf 4; Krüppel-like factor 4; TNF-α; tumor necrosis factor-a; IL-1β; interleukin-1β; iNOS; inducible nitric oxide synthase; COX-2; cyclooxygenase-2; CNS; central neural system; LPS; lipopolysaccharide; HFIP;
Macrophage C-type lectin is essential for phagosome maturation and acidification during Escherichia coli-induced peritonitis
Keywords: MCL; E. coli-induced peritonitis; Macrophage; Bacterial killing; Phagosome maturation; Phagosome acidification; MCL; macrophage C-type lectin; CLRs; C-type lectin receptors; CRD; carbohydrate recognition domains; PRRs; pattern recognition receptors; TLRs
CD200 selectively upregulates prostaglandin E2 and D2 synthesis in LPS-treated bone marrow-derived macrophages
Keywords: CD200; Cluster of Differentiation 200 also named OX-2 membrane glycoprotein; CD200R; CD200 receptor; CFA; Complete Freund's Adjuvant; COX; cyclooxygenase; HPGDS; hematopoietic PGD synthase; IL; interleukin; IFNγ; interferon γ; LPGDS; Lipocalin-type PG
Glibenclamide inhibits NLRP3 inflammasome-mediated IL-1β secretion in human trophoblasts
Keywords: Inflammasome; TLR4; NLRP3; Caspase-1; Trophoblast; AS; Antisense; ASC; Apoptosis-associated speck-like protein containing a caspase recruitment domain; CAM; Chorioamnionitis; COX; Cyclooxygenase; Db-cAMP; N6, 2â² -0-Dibutyryladenosine 3â², 5â²-cyclic m
Short communicationsÏ-3 polyunsaturated fatty acid supplementation ameliorates lipopolysaccharide-induced behavioral deficits and modulates neurotrophic factors in rats: Focus on tPA/PAI-1 system and BDNF-TrkB signaling
Keywords: BDNF; brain-derived neurotrophic factor; LPS; lipopolysaccharide; NGF; nerve growth factor; PAI-1; plasminogen activator inhibitor-1; PUFA; polyunsaturated fatty acid; tPA; tissue plasmogen activator; SSRI; selective serotonin reuptake inhibitor; TrkB; tr
CD14 is not involved in the uptake of synthetic CpG oligonucleotides
Keywords: EDTA; ethylenediamine tetra-acetic acid disodium salt; PE; phycoerythrin; SA; streptavidin; PBS; phosphate buffered saline; i.v.; intravenous; LPS; lipopolysaccharide; Dendritic cells; CD14; CpG; DNA receptor; Pathogen pattern recognition receptor;
Research ArticleIn vivo modulation of LPS induced leukotrienes generation and oxidative stress by sesame lignans
Keywords: LPS; Inflammation; Cytokines; Leukotrienes; Sesamol; Sesamin;
Research PaperDidox (3,4-dihydroxybenzohydroxamic acid) suppresses IL-33-induced cytokine production in primary mouse mast cells
Keywords: BMMC; bone marrow derived mast cell; HU; hydroxyurea; LPS; lipopolysaccharide; NAC; N-acetylcysteine; RNR; ribonucleotide reductase; Didox; IL-33; Mast cells; NFκB; AP-1; Allergic inflammation;
Research paperSodium azide suppresses LPS-induced expression MCP-1 through regulating IκBζ and STAT1 activities in macrophages
Keywords: LPS; MCP-1; Signaling; Macrophage; STAT1; IκBζ;
iTRAQ-based quantitative proteomic analysis reveals Bai-Hu-Tang enhances phagocytosis and cross-presentation against LPS fever in rabbit
Keywords: TCM; traditional Chinese medicine; BHT; Bai-Hu-Tang; LPS; lipopolysaccharide; iTRAQ; isobaric tags for relative and absolute quantification; LC-MS/MS; liquid chromatography - tandem mass spectrometry; DEPs; differently expressed proteins; GO; Gene Ontolog
Palmatine inhibits TRIF-dependent NF-κB pathway against inflammation induced by LPS in goat endometrial epithelial cells
Keywords: Palmatine; LPS; anti-inflammatory mechanism; TLR4; NF-κB pathway;
Protective effect of zerumbone reduces lipopolysaccharide-induced acute lung injury via antioxidative enzymes and Nrf2/HO-1 pathway
Keywords: ALI; Acute lung injury; AOE; antioxidative enzymes; BALF; bronchoalveolar lavage fluid; CAT; catalase; DMSO; dimethyl sulfoxide; GPx; glutathione peroxidase; HO-1; heme oxygenase; IP; intraperitoneal; IT; intratracheal; LPS; Lipopolysaccharide; MDA; malon
Research PaperA double blind randomized experimental study on the use of IgM-enriched polyclonal immunoglobulins in an animal model of pneumonia developing shock
Keywords: ABG; arterial blood gas; BAL; bronchoalveolar lavage; CTR; control group; FiO2; fraction of inspiratory oxygen; IFN-γ; interferon-γ; IgG; Immunoglobulin G; IgM; Immunoglobulin M; IL; interleukin; LDH; lactate dehydrogenase; LPS; lipopolysaccharide; MAP;
Research paperAdhesion attenuates respiratory burst induced by different modes of triggering in resting or LPS-primed neutrophils
Keywords: BSA; bovine serum albumin; fMLP; N-formyl-methionyl-leucyl-phenylalanine; IL-8; interleukin-8; LPS; lipopolysaccharide; O2â; superoxide anion; Pam3CSK4; tripalmitoyl-S-glyceryl-l-Cys-Ser-(Lys)4; PBS; phosphate buffered saline; poly HEMA; polyhydroxyl-et
Vaccination with Shigella flexneri 2a conjugate induces type 2a and cross-reactive type 6 antibodies in humans but not in mice
Keywords: Shigella flexneri; LPS; Antibody; Cross-reactivity; Vaccine;
Development, phenotype, and function of non-conventional B cells
Keywords: ATA; anti T cell antigen; BCR; B cell receptor; IGHV; immunoglobulin heavy chain variable gene; LPS; lipopolysaccharide; MDA; malondialdehyde; MZ; marginal Zone; MFI; mean fluorescence intensity; N-nucleotide; non-template nucleotide; OVA; ovalbumin; PC;
Genome-guided transcriptome analysis of miiuy croaker provides insights into pattern recognition receptors and cytokines in response to Vibrio anguillarum
Keywords: Transcriptome; Vibrio anguillarum; Pattern recognition receptors; Cytokines; LPS; Macrophage;
Molecular characterisation, evolution and expression analysis of g-type lysozymes in Ciona intestinalis
Keywords: Ascidian; Lysozymes g-type; Inflammation; LPS; Ciona intestinalis;