Activation of microglia by aggregated β-amyloid or lipopolysaccharide impairs MHC-II expression and renders them cytotoxic whereas IFN-γ and IL-4 render them protective
Keywords: Aβ(1-40); β-amyloid (1-40) peptide; APC; antigen-presenting cell; CIITA; MHC class II transactivator; CNS; central nervous system; FCS; fetal calf serum; IB4; isolectin-B4; IGF-I; insulin-like growth factor I; IFN; interferon; IL; interleukin; Ii; i