کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9009971 | 1560417 | 2005 | 15 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Medicinal use of Cochlospermum tinctorium in Mali
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کلمات کلیدی
XylDMTConAarabinogalactan type IIHPAEC-PADGlcAPectic arabinogalactanArabinoseGlcRHAFucoseFucBioactive polysaccharidesAlkaline phosphatase assayCochlospermaceaeFPLCPMIIDPPHCochlospermum tinctoriumFBSAGIILPSPBSAnti-IgMGalacturonic acid - اسید گالاکاتورونیکGlucuronic acid - اسید گلوکورونیکImmunomodulation - تنظیم ایمنی ARA - در حال حاضرrhamnose - رامنوزRadical scavenging - ریخته گری رادیکالfetal bovine serum - سرم جنین گاوAnti-ulcer - ضد زخمphycoerythrin - فایکوئیریدینFerulic acid - فرولیک اسیدDulbecco's phosphate buffered saline - فسفات باسیل نمک Dulbeccolipopolysaccharide - لیپوپلی ساکاریدMali - مالزیMannose - مانوزMan - مردPolyphenols - پلیفنلهاhigh performance anion exchange chromatography with pulsed amperometric detection - کروماتوگرافی مبدل آنیون با عملکرد بالا با تشخیص آمپومتریک پالسGal - گالGalA - گالاGalactose - گالاکتوزمی Xylose - گزیلوزGlucose - گلوکز
موضوعات مرتبط
علوم پزشکی و سلامت
داروسازی، سم شناسی و علوم دارویی
داروشناسی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Cochlospermum tinctorium A. Rich. (Cochlospermaceae) is a widely used medicinal plant in the West African country, Mali. An ethnopharmacological survey was conducted and 106 traditional practitioners interviewed. The roots were the part of the plant reported to be the most frequently used for medicinal purposes. The main indications were to treat jaundice (41), gastro intestinal diseases or ailments (28), malaria (12), schistosomiasis (10) and dysurea (6). A high-molecular weight water extract (25, 50 and 100Â mg/kg, body weight) significantly inhibited HCl/ethanol-induced gastric lesions in mice. The extract showed DPPH-radical scavenging- and immunomodulating activities in vitro. The main components of the extract were identified as polysaccharides (59.3%) and polyphenols (9.3%). The polysaccharides were purified and characterised as highly complex pectic arabinogalactans type II. As parts of the polyphenol compounds gallotannins and ferulic acids were identified. This study shows that the polysaccharides are partly responsible for the bioactivities observed in vitro. Both polysaccharides and polyphenols may be responsible for the anti-ulcer activities observed.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Ethnopharmacology - Volume 96, Issues 1â2, 4 January 2005, Pages 255-269
Journal: Journal of Ethnopharmacology - Volume 96, Issues 1â2, 4 January 2005, Pages 255-269
نویسندگان
Cecilie Sogn Nergard, Drissa Diallo, Kari Inngjerdingen, Terje Einar Michaelsen, Tsukasa Matsumoto, Hiroaki Kiyohara, Haruki Yamada, Berit Smestad Paulsen,