دانلود مقالات ISI درباره Lxr + ترجمه فارسی

28-Homocastasterone down regulates blood glucose, cholesterol, triglycerides, SREBP1c and activates LxR expression in normal & diabetic male rat

Keywords: 28-Homocastasterone; Blood glucose; Cholesterol; Triglyceride; Liver x Receptor; 28-HC; 28-homocastasterone; LxR; Liver x Receptor; ABCT; ATP-binding cassette transporters; SREBP1c; sterol regulatory element binding protein-1c; TNF-α; Tumor necrosis fact

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Full Length Article1α-Hydroxy derivatives of 7-dehydrocholesterol are selective liver X receptor modulators

Keywords: LXR; liver X receptor; 24,25-EC; 24(S),25-epoxycholesterol; 22R-HC; 22(R)-hydroxycholesterol; RXR; retinoid X receptor; ABC; ATP-binding cassette; SREBP-1c; sterol regulatory element-binding protein 1c; 7-DHC; 7-dehydrocholesterol; 1,25(OH)2D3; 1α,25-dih

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Regulated efflux of photoreceptor outer segment-derived cholesterol by human RPE cells

Keywords: ABCA1; RPE; Cholesterol efflux; HDL; LXR; ApoA-I;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Ligand-dependent and -independent regulation of human hepatic sphingomyelin phosphodiesterase acid-like 3A expression by pregnane X receptor and crosstalk with liver X receptor

Keywords: DR; direct repeat; EMSA; electrophoretic mobility shift assay; ER; everted repeat; LXR; liver X receptor; PXR; pregnane X receptor; RXR; retinoid X receptor; SMPDL; sphingomyelin phosphodiesterase acid-like; Rifampin (PubChem CID: 6243627); GW3965 hydroch

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Characterization of stem cell-derived liver and intestinal organoids as a model system to study nuclear receptor biology

Keywords: ChIP; chromatin immunoprecipitation; DIC; differential interference contrast; DM; differentiation medium; DSG; Di(N-succinimidyl) glutarate; EM; expansion medium; Fxr; farnesoid x receptor; IPA; Ingenuity Pathway Analysis; Lxr; Liver x receptor; NR; nucle

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

Metabolic roles of poly(ADP-ribose) polymerases

Keywords: ABCA1; ATP-binding cassette sub-family A member 1; ACACA; acetyl-CoA carboxylase alpha; ACBD3; acyl-CoA binding domain containing 3; ACLY; ATP citrate lyase; ADP; adenosine diphosphate; ADPR; ADP-ribose; AFLD; alcoholic fatty liver disease; AIF; apoptosis

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2017 سفارش ترجمه

Protective effects of gomisin N against hepatic steatosis through AMPK activation

Keywords: Gomisin N; Nonalcoholic fatty liver disease; Lipogenesis; AMP-activated protein kinase; Sterol regulatory element-binding protein 1c; High-fat diet; ACC; Acetyl-CoA carboxylase; AMPK; Adenosine monophosphate (AMP)-activated protein kinase; CPT 1; Carnitin

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2017 سفارش ترجمه

Role of the liver X receptors in skin physiology: Putative pharmacological targets in human diseases

Keywords: ABCA1; ATP-binding cassette 1; ABCA12; ATP-binding cassette 12; ABCG1; ATP binding cassette subfamily G member 1; Apo; apolipoprotein; CAT; catalase; COX-2; cyclo-oxygenase-2; DR4; direct repeat 4; EGCG; epigallocatechin-3-gallate; ERK; extracellular sign

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2017 سفارش ترجمه

Circulating oxysterol metabolites as potential new surrogate markers in patients with hormone receptor-positive breast cancer: Results of the OXYTAM study

Keywords: BC; breast cancer; Tam; tamoxifen; AEBS; antiestrogen binding site; ET; endocrine therapy; OS; oxysterol; AI; aromatase inhibitors; 24-HC; 24-hydroxycholesterol; 25-HC; 25-hydroxycholesterol; 27-HC; 27-hydroxycholesterol; 7α-HC; 7α-hydroxycholesterol; 7

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه

Effect of dietary fatty acid composition on growth, fatty acids composition and hepatic lipid metabolism in juvenile turbot (Scophthalmus maximus L.) fed diets with required n3 LC-PUFAs

Keywords: LC-PUFA; Long-chain polyunsaturated fatty acid; HDL-c/LDL-c; Ratio of high- to low-density lipoprotein cholesterol; LPL; Lipoprotein lipase; G6PD; Glucose-6-phosphate dehydrogenase; ME; Malic enzyme; ApoB-100; Apolipoprotein B-100; PPARα; Peroxisome prol

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2017 سفارش ترجمه

Ageing sensitized by iPLA2β deficiency induces liver fibrosis and intestinal atrophy involving suppression of homeostatic genes and alteration of intestinal lipids and bile acids

Keywords: ACC; acetyl-CoA carboxylase; ATF6; activating transcription factor6; AB-PAS; alcian blue-periodic acidschiff; ACC; acetyl-CoA carboxylase; ACSL; long-chain acyl-CoA synthetase; Bad; Bcl-2-associated death promoter; Bax; Bcl-2-like protein 4; Bcl-2; B-cell

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2017 سفارش ترجمه

Dual signaling evoked by oxidized LDLs in vascular cells

Keywords: AAPH; 2,2'-azobis(2-amidinopropane) dihydrochloride; AIF; apoptotic inducing factor; AMVN; 2,4-dimethylvaleronitrile; AP-1; activator protein 1; ATF6; activating transcription factor 6; CDE; clathrin-dependent endocytosis; CCL2; chemokine ligand 2 (or MCP

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2017 سفارش ترجمه

G0S2: A small giant controller of lipolysis and adipose-liver fatty acid flux

Keywords: G0S2; G0/G1 switch gene 2; HSL; hormone-sensitive lipase; ATGL; adipose triglyceride lipase; TG; triacylglycerol/triglyceride; FA; fatty acid; BAT; brown adipose tissue; WAT; white adipose tissue; PPAR; peroxisome proliferator-activated receptor; PPRE; PP

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2017 سفارش ترجمه

PPARα-independent transcriptional targets of perfluoroalkyl acids revealed by transcript profiling

Keywords: AhR; aryl hydrocarbon receptor; CAR; constitutive activated receptor; DEHP; di-(2-ethylhexyl)phthalate; ERα; estrogen receptor α; ERE; estrogen response element; GH; growth hormone; LXR; liver X receptor; Nrf2; nuclear factor erythroid-2-related factor

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2017 سفارش ترجمه

Molecular aspects of lipid metabolism, digestibility and antioxidant status of Atlantic bluefin tuna (T. thynnus L.) larvae during first feeding

Keywords: ABT; Atlantic bluefin tuna; aco; acyl coA oxidase; alp; alkaline phosphatase; amy; amylase; anpep; amino peptidase; ARA; arachidonic acid (20:4n-6); bal1; bile salt activated lipase 1; bal2; bile salt activated lipase 2; C; free cholesterol; cat; catalase

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2017 سفارش ترجمه

Indazole-based ligands for estrogen-related receptor α as potential anti-diabetic agents

Keywords: Estrogen-related receptor α; ERRα; Nuclear receptor; Anti-diabetic; Metabolic syndrome; Indazole; Thiazolidenedione; TZD; Insulin resistance; ERR; estrogen-related receptor; ER; estrogen receptor; ERE; estrogen response element; ERRE; estrogen-related r

دانلود رایگان متن کامل مقاله ISI 73 صفحه سال انتشار : 2017 سفارش ترجمه

Genome-Wide Association Studies Candidate Gene to Dual Modifier of Nonalcoholic Steatohepatitis and Atherosclerosis

Keywords: atherosclerosis; fatty liver; genome-wide association studies; LXR; steatohepatitis;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Promiscuous activity of the LXR antagonist GSK2033 in a mouse model of fatty liver disease

Keywords: Nuclear receptor; LXR; Transcription; NASH; Lipogenesis; Drug discovery;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Radioligand binding assay for accurate determination of nuclear retinoid X receptors: A case of triorganotin endocrine disrupting ligands

Keywords: ATRA; all-trans retinoic acid; Bmax; maximal binding capacity (pmol/mg); DNA; deoxyribonucleic acid; DR; direct repeat; DTT; 1,4-dithiothreitol; FXR; farnesoid X receptor; Ka; affinity (l/mol); LBD; ligand-binding domain; LXR; liver X receptor; PMSF; phen

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

The macrophage and its related cholesterol efflux as a HDL function index in atherosclerosis

Keywords: ABC; ATP-binding cassette; ABCA-1; ATP-binding cassette A-1; ABCG-1; ATP-binding cassette G-1; CKD; chronic kidney disease; CVD; cardiovascular disease; HDL; high-density lipoprotein; IL; interleukin; IQR; interquartile range; LDL; low-density lipoprotein

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Hepatic maturation of human iPS cell-derived hepatocyte-like cells by ATF5, c/EBPα, and PROX1 transduction

Keywords: Human induced pluripotent stem cells; Hepatocyte; Drug metabolism; ATF5; c/EBPα; PROX1; Human iPS-HLCs; Human induced pluripotent stem cells-derived hepatocyte-like cells; HLCs; Hepatocyte-like cells; ATF5; Activating transcription factor 5; c/EBPα; CCA

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

LXR activation protects hippocampal microvasculature in very old triple transgenic mouse model of Alzheimer's disease

Keywords: AD; Alzheimer's disease; BBB; blood brain barrier; Aβ; Amyloid beta; LRP1; low-density lipoprotein related protein 1; LXR; liver X receptor; GFAP; glial fibrillary acidic protein; Iba1; ionized calcium-binding adapter molecule 1; GW3965; Alzheimer's

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Transcriptional regulation of the human Liver X Receptor α gene by Hepatocyte Nuclear Factor 4α

Keywords: LXR; HNF-4α; Gene regulation; HDL; Oxysterols; ABCA1; ATP Binsing Cassette Transporter A1; ChIP; Chromatin Immunoprecipitation; ChIP-seq; Chromatin Immunoprecipitation followed by sequencing; DNAP; DNA Affinity Precipitation; HNF-4; Hepatocyte Nuclear Fa

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Brain penetrant liver X receptor (LXR) modulators based on a 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole core

Keywords: LXR; Structure-based drug design; Alzheimer's disease; Brain;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

LXR agonist rescued the deficit in the proliferation of the cerebellar granule cells induced by dexamethasone

Keywords: Dexamethasone; Cerebellum; Development; Proliferation; LXR;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

MicroRNAs in brain cholesterol metabolism and their implications for Alzheimer's disease

Keywords: AAV; adeno associated virus; ABC; ATP-binding cassette; ABCA1; ABC transporter A1; AD; Alzheimer's disease; APOA-I; apolipoprotein A1; APOE; apolipoprotein E; APP; amyloid β precursor protein; BBB; blood-brain barrier; CE; cholesteryl ester; CETP; chol

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Pleiotropic effects of antitumour alkylphospholipids on cholesterol transport and metabolism

Keywords: ABCA1; ATP-binding cassette transporter isoform A1; APL; alkylphospholipid; apoA1; apolipoprotein A1; CETP; cholesteryl ester transfer protein; CYP7A1; cholesterol 7α-hydroxylase; CYP27; sterol 27-hydroxylase; DHCR7; 7-dehydrocholesterol reductase; ER; e

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Nrf2 antioxidant defense is involved in survival signaling elicited by 27-hydroxycholesterol in human promonocytic cells

Keywords: ARE; antioxidant response element; CYP27A1; 27-hydroxylase; DAPI; 4,6-diamidino-2-phenylindole; DPI; diphenyleneiodonium chloride; ERK; extracellular signal-regulated kinase; GPx; glutathione peroxidase; GSR; glutathione reductase; HO-1; heme oxygenase-1;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Crabapple fruit extracts lower hypercholesterolaemia in high-fat diet-induced obese mice

Keywords: Crabapple; Hyperlipidaemia; Hypercholesterolaemia; Metabolic syndrome; Anti-oxidation; CYP7A1; Procyanidin (PubChem CID: 107876); Epicatechin (PubChem CID: 72276); Isoastilbin (PubChem CID: 10114809); Quercetin 3-O-glucoside (PubChem CID: 44258003); Avicu

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

miRNA and cholesterol homeostasis

Keywords: miRNA; microRNA; SREBP; sterol regulatory element-binding protein; SCAP; SREBP cleavage-activating protein; Ago; Argonaute family protein; RISC; RNA-induced-silencing-complex; Fbxw7; F-box and WD repeat domain containing 7; NAFLD; non-alcoholic fatty live

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2016 سفارش ترجمه

Liver X Receptor Regulates Triglyceride Absorption Through Intestinal Down-regulation of Scavenger Receptor Class B, Type 1

Keywords: Hypertriglyceridemia; Lipid-Sensing; Fat Absorption; Triglyceride-Rich Lipoproteins; apoB; apolipoprotein B; BBM; brush-border membrane; CM; chylomicron; DMSO; dimethyl sulfoxide; LXR; liver X receptor; mRNA; messenger RNA; PDZK1; PDZ-containing kidney pr

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2016 سفارش ترجمه

MEK1/2 inhibitors activate macrophage ABCG1 expression and reverse cholesterol transport-An anti-atherogenic function of ERK1/2 inhibition

Keywords: ABCG1; Atherosclerosis; LXR; MEK1/2; RCT; SIRT1;

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2016 سفارش ترجمه

HDL functionality in reverse cholesterol transport - Challenges in translating data emerging from mouse models to human disease

Keywords: ABC; ATP-binding cassette transporter; Apo; apolipoprotein; apobec1; apoB mRNA editing enzyme; ASBT; apical sodium-dependent bile acid transporter; BA; bile acids; BAT; bile acid CoA:amino acid N-acyltransferase; BSEP; bile salt export pump; CEC; choleste

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2016 سفارش ترجمه

Oxysterols: From cholesterol metabolites to key mediators

Keywords: ABC; ATP-binding cassette; ACAT; acyl-coenzyme A cholesterol acyltransferase; C4; 7-hydroxycholestenone; CA; cholestanoic acid; CH25H; cholesterol-25-hydroxylase; ChEH; cholesterol epoxide hydrolase; CNS; central nervous system; CSF; cerebrospinal fluid;

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2016 سفارش ترجمه

The LXR inverse agonist SR9238 suppresses fibrosis in a model of non-alcoholic steatohepatitis

Keywords: NASH; Fibrosis; Lipogenesis; LXR; InflammationNASH, non-alcoholic steatohepatitis; LXR, Liver-X-Receptor; HTF, high trans-fat diet; NR, nuclear receptor

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

RIP140 triggers foam-cell formation by repressing ABCA1/G1 expression and cholesterol efflux via liver X receptor

Keywords: ABCA1; ATP-binding cassette transporter A1; ABCG1; ATP-binding cassette transporter G1; apoA-I; apolipoprotein A-I; CD36; cluster of differentiation 36; ERR; estrogen receptor-related receptor; HDL; high-density lipoprotein; LXR; liver X receptor; LXRE; l

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Regulation of retinoid X receptor gamma expression by fed state in mouse liver

Keywords: RXRγ; Liver; Feeding; Glucose; Lipid metabolism; RXR; retinoid X receptor; PPARγ; peroxisome proliferator-activated receptor gamma; RAR; retinoic acid receptor; FXR; farnesoid X receptor; LXR; liver X receptor; SREBP-1c; sterol regulatory element-bindin

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Regulation of retinoid mediated cholesterol efflux involves liver X receptor activation in mouse macrophages

Keywords: Retinoids; LXR; ABCA1; StAR; HSL; Cholesterol efflux; Macrophages;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

LXR ligands sensitize EGFR-TKI-resistant human lung cancer cells in vitro by inhibiting Akt activation

Keywords: LXR; Gefitinib; Drug resistance; Lung cancer;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Liver X Receptor (LXR) partial agonists: Biaryl pyrazoles and imidazoles displaying a preference for LXRβ

Keywords: SWBBNSPWRVCYAE-UHFFFAOYSA-N; WZMZHHPXANSLBG-UHFFFAOYSA-N; KMTFPMRUPSWRTQ-UHFFFAOYSA-N; DIRKHQVAVLSYMA-UHFFFAOYSA-N; XQWURCYLMCTAFE-UHFFFAOYSA-N; STNGIHCHDLCYEV-UHFFFAOYSA-N; VOOZJAGZCXOELE-UHFFFAOYSA-N; ZXTOKWKHXXGVMT-UHFFFAOYSA-N; SALZQMSOIKCKNM-UHFFFAOY

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Basic ScienceABCG8 polymorphisms and renal disease in type 2 diabetic patients

Keywords: ABCG; ATP-binding-cassette, subfamily G; LXR; liver X receptor; FXR; farnesoid X receptor; MAF; minor allele frequency; SBP; systolic blood pressure; DBP; diastolic blood pressure; UAE; urinary albumin excretion; CRP; C-reactive protein; Diabetic nephropa

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Research ArticleHepatic estrogen receptor α improves hepatosteatosis through upregulation of small heterodimer partner

Keywords: NAFLD; Non-alcoholic fatty liver disease; ERα; estrogen receptor α; FXR; farnesoid X receptor; SHP; small heterodimer partner; TG; Triglyceride; LXR; liver X receptor; ERβ; estrogen receptor β; HFD; High-Fat Diet; SREBP-1c; sterol regulatory element b

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

RIP140 contributes to foam cell formation and atherosclerosis by regulating cholesterol homeostasis in macrophages

Keywords: LDL; low density lipoprotein; HDL; high density lipoprotein; RIP140; receptor interacting protein 140; ABCA1; ATP-binding membrane cassette transporter A-1; ABCG1; ATP-binding membrane cassette transporter G-1; RCT; reverse cholesterol transport; oxLDL; o

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Liver X receptors at the intersection of lipid metabolism and atherogenesis

Keywords: Nuclear receptor; Atherosclerosis; LXR; Lipid metabolism;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Behavioral stress reduces RIP140 expression in astrocyte and increases brain lipid accumulation

Keywords: ABCA; ATP-binding cassette transporter; ABCG1; ATP-binding cassette sub-family G; ApoE; Apolipoprotein E; CYP46; cholesterol 24S-hydroxylase; CYP51; Sterol 14 alpha-demethylase; ER; endoplasmic reticulum; FSS; forced swim stress; H2O2; Hydrogen peroxide;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Tunicate pregnane X receptor (PXR) orthologs: Transcript characterization and natural variation

Keywords: AF-1; transcription activation function 1; AR; androgen receptor; BsVDR/PXRα; Botryllus schlosseri VDR/PXR ortholog α; BSA; bovine serum albumin; bp; base pair; CAR; constitutive androstane receptor; CiVDR/PXRα; Ciona intestinalis VDR/PXR ortholog α;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Glucocorticoids enhance prolonged clearance of apoptotic cells by upregulating liver X receptor, peroxisome proliferator-activated receptor-δ and UCP2

Keywords: BMDM; bone marrow derived macrophage; C1qb; complement 1qb; C/EBP; CCAAT/enhancer binding protein; CFDA; carboxyfluorescein diacetate succinimidyl ester; CHX; cycloheximide; CMTMR; 5-(and-6)-(((4-chloromethyl)benzoylamino)tetramethylrhodamine); CYP27; a m

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Cytokines in atherosclerosis: Key players in all stages of disease and promising therapeutic targets

Keywords: Atherosclerosis; Cytokines; Chemokines; Inflammation; Therapeutic avenues; ABC; ATP-binding cassette; ACAT-1; acyl-CoA acyl transferase-1; ADRP; adipocyte differentiation related protein; Apo; apolipoprotein; BMT; bone marrow transplantation; CANTOS; Cana

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Caloric restriction, resveratrol and melatonin: Role of SIRT1 and implications for aging and related-diseases

Keywords: Aβ; amyloid β protein; AMPK; adenosine monophosphate activated protein kinase; CGNs; cerebellar granule neurons; ETC; electron transport chain; H2O2; hydrogen peroxide; HO-1; heme oxygenase-1; LXR; liver X receptor; MAPK; mitogen-activated protein kinas

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Destabilization of the torsioned conformation of a ligand side chain inverts the LXRβ activity

Keywords: ABCG1; ATP-binding cassette sub-family G member 1; FASN; Fatty Acid Synthase gene; LBP; Ligand binding pocket; LXR; Liver X receptor; MD; Molecular Dynamics; NR; Nuclear receptor; SREBP-1a/c; Sterol Response Element Binding Protein1 isoforms a and c; Live

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2015 سفارش ترجمه